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Scientific Principles Of Adipose Stem Cells

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Scientific Principles of Adipose Stem Cells

Scientific Principles of Adipose Stem Cells Book
Author : Lauren Kokai,Kacey Marra,J. Peter Rubin
Publisher : Elsevier
Release : 2021-09-15
ISBN : 012819376X
Language : En, Es, Fr & De

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Book Description :

Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. Coverage of basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche Includes important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype An entire section dedicated to ASC biology, additional sections will be devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications

Scientific Principles of Adipose Stem Cells

Scientific Principles of Adipose Stem Cells Book
Author : Lauren Kokai,Kacey Marra,J. Peter Rubin
Publisher : Academic Press
Release : 2021-09-01
ISBN : 0128193778
Language : En, Es, Fr & De

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Book Description :

Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. Coverage of basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche Includes important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype An entire section dedicated to ASC biology, additional sections will be devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications

Principles of Regenerative Medicine

Principles of Regenerative Medicine Book
Author : Anthony Atala,Robert Lanza,Tony Mikos,Robert Nerem
Publisher : Academic Press
Release : 2018-08-09
ISBN : 0128098937
Language : En, Es, Fr & De

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Book Description :

Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue. Contributions from a stellar cast of researchers cover the biological and molecular basis of regenerative medicine, highlighting stem cells, wound healing and cell and tissue development. Advances in cell and tissue therapy, including replacement of tissues and organs damaged by disease and previously untreatable conditions, such as diabetes, heart disease, liver disease and renal failure are also incorporated to provide a view to the future and framework for additional studies. Comprehensively covers the interdisciplinary field of regenerative medicine with contributions from leaders in tissue engineering, cell and developmental biology, biomaterials sciences, nanotechnology, physics, chemistry, bioengineering and surgery Includes new chapters devoted to iPS cells and other alternative sources for generating stem cells as written by the scientists who made the breakthroughs Edited by a world-renowned team to present a complete story of the development and promise of regenerative medicine

Regenerative Engineering

Regenerative Engineering Book
Author : Yusuf Khan,Cato T. Laurencin
Publisher : CRC Press
Release : 2018-04-19
ISBN : 1351647393
Language : En, Es, Fr & De

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Book Description :

This book focuses on advances made in both materials science and scaffold development techniques, paying close attention to the latest and state-of-the-art research. Chapters delve into a sweeping variety of specific materials categories, from composite materials to bioactive ceramics, exploring how these materials are specifically designed for regenerative engineering applications. Also included are unique chapters on biologically-derived scaffolding, along with 3D printing technology for regenerative engineering. Features: Covers the latest developments in advanced materials for regenerative engineering and medicine. Each chapter is written by world class researchers in various aspects of this medical technology. Provides unique coverage of biologically derived scaffolding. Includes separate chapter on how 3D printing technology is related to regenerative engineering. Includes extensive references at the end of each chapter to enhance further study.

Progenitor and Stem Cell Technologies and Therapies

Progenitor and Stem Cell Technologies and Therapies Book
Author : Anthony Atala
Publisher : Elsevier
Release : 2012-03-15
ISBN : 0857096079
Language : En, Es, Fr & De

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Book Description :

Progenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application. Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. These include human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells. Part two discusses wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies. The final part of the book considers the therapeutic use of stem and progenitor cells. Chapters review the use of adipose tissue-derived stem cells, umbilical cord blood (UCB) stem cells, bone marrow, auditory and oral cavity stem cells. Other chapters cover the use of stem cells in therapies in various clinical areas, including lung, cartilage, urologic, nerve and cardiac repair. With its distinguished editor and international team of contributors, Progenitor and stem cell technologies and therapies is a standard reference for both those researching in cell and tissue biology and engineering as well as medical practitioners investigating the therapeutic use of this important technology. Reviews the range of progenitor and stem cells available and outlines their therapeutic application Examines the basic principles for the culture of stem cells before discussing technologies for particular cell types, including human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells Includes a discussion of wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies

Biomaterials and Stem Cells in Regenerative Medicine

Biomaterials and Stem Cells in Regenerative Medicine Book
Author : Murugan Ramalingam,Seeram Ramakrishna,Serena Best
Publisher : CRC Press
Release : 2012-07-03
ISBN : 1439879257
Language : En, Es, Fr & De

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Book Description :

Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent research on suitable cell scaffolds and substrates for tissue repair and reconstruction. Featuring contributions by experts in the field, the book explores important scientific and clinical aspects. It covers the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications of biomaterials and stem cells. Topics include: Polymeric systems for stem cell delivery The potential of membranes and porous scaffolds in tissue repair, including myocardial, periodontal, ophthalmic, and bone tissues The optimization of the interaction between stem cells and biomaterial substrates The source and nature of stem cells for tissue engineering applications The clinical translation of stem cell–based tissue engineering for regenerative medicine From fundamental principles to recent advances at the macro, micro, nano, and molecular scales, the book brings together current knowledge on biomaterials and stem cells in the context of regenerative medicine. It also stimulates discussion about future research directions. This unique book offers a valuable benchmark for the current status of clinically relevant research and development in stem cells and regenerative medicine. It bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for graduate students, researchers, and practitioners working in the multidisciplinary field of biomedical research.

Regenerative Engineering

Regenerative Engineering Book
Author : Yusuf Khan,Cato T. Laurencin
Publisher : CRC Press
Release : 2018-04-19
ISBN : 1498738257
Language : En, Es, Fr & De

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Book Description :

This book focuses on advances made in both materials science and scaffold development techniques, paying close attention to the latest and state-of-the-art research. Chapters delve into a sweeping variety of specific materials categories, from composite materials to bioactive ceramics, exploring how these materials are specifically designed for regenerative engineering applications. Also included are unique chapters on biologically-derived scaffolding, along with 3D printing technology for regenerative engineering. Features: Covers the latest developments in advanced materials for regenerative engineering and medicine. Each chapter is written by world class researchers in various aspects of this medical technology. Provides unique coverage of biologically derived scaffolding. Includes separate chapter on how 3D printing technology is related to regenerative engineering. Includes extensive references at the end of each chapter to enhance further study.

Regenerative Medicine and Tissue Engineering

Regenerative Medicine and Tissue Engineering Book
Author : Daniel Eberli
Publisher : IntechOpen
Release : 2011-08-29
ISBN : 9789533076638
Language : En, Es, Fr & De

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Book Description :

Tissue Engineering may offer new treatment alternatives for organ replacement or repair deteriorated organs. Among the clinical applications of Tissue Engineering are the production of artificial skin for burn patients, tissue engineered trachea, cartilage for knee-replacement procedures, urinary bladder replacement, urethra substitutes and cellular therapies for the treatment of urinary incontinence. The Tissue Engineering approach has major advantages over traditional organ transplantation and circumvents the problem of organ shortage. Tissues reconstructed from readily available biopsy material induce only minimal or no immunogenicity when reimplanted in the patient. This book is aimed at anyone interested in the application of Tissue Engineering in different organ systems. It offers insights into a wide variety of strategies applying the principles of Tissue Engineering to tissue and organ regeneration.

Mesenchymal Stem Cells Basics and Clinical Application II

Mesenchymal Stem Cells   Basics and Clinical Application II Book
Author : Birgit Weyand,Massimo Dominici,Ralf Hass,Roland Jacobs,Cornelia Kasper
Publisher : Springer
Release : 2014-07-08
ISBN : 3642379443
Language : En, Es, Fr & De

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Book Description :

Engineered MSCs from Patient-Specific iPS Cells, by Irina Eberle, Mohsen Moslem, Reinhard Henschler, Tobias Cantz Fate of Intravenously Injected Mesenchymal Stem Cells and Significance for Clinical Application, by Beate Wagner, Reinhard Henschler The Implications of Stem Cell Applications for Diseases of the Respiratory System, by Mei Ling Lim, Philipp Jungebluth, Paolo Macchiarini Potential of Mesenchymal Stem Cell Applications in Plastic and Reconstructive Surgery, by Birgit Weyand, Peter M. Vogt General Principles for the Regeneration of Bone and Cartilage, by Michael Jagodzinski, C. Haasper Adult Mesenchymal Stem Cells Explored in the Dental Field, by K. M. Fawzy El-Sayed, C. Dörfer, F. Fändrich, F. Gieseler, M. H. Moustafa, H. Ungefroren Mesenchymal Stem Cell Therapy and Lung Diseases, by Khondoker M. Akram, Sohel Samad, Monica Spiteri, Nicholas R. Forsyth Mesenchymal Stem Cells as Cellular Immunotherapeutics in Allogeneic Hematopoietic Stem Cell Transplantation, by Claudia Papewalis, Daniela Topolar, Barbara Götz, Stefan Schönberger, Dagmar Dilloo New Cell-Based Therapy Paradigm: Induction of Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells into Pro-Inflammatory MSC1 and Anti-inflammatory MSC2 Phenotypes, by Aline M. Betancourt Interactions Between Mesenchymal Stem Cells and Dendritic Cells, by Grazia Maria Spaggiari, Lorenzo Moretta MSC and Tumors: Homing, Differentiation, and Secretion Influence Therapeutic Potential, by Naomi D’souza, Jorge Sans Burns, Giulia Grisendi, Olivia Candini, Elena Veronesi, Serena Piccinno, Edwin M. Horwitz, Paolo Paolucci, Pierfranco Conte, Massimo Dominici Sources of Mesenchymal Stem Cells: Current and Future Clinical Use, by Michela Pozzobon, Martina Piccoli, Paolo De Coppi Role of the EU Framework in Regulation of Stem Cell-Based Products, by Giovanni Migliaccio, Cristina Pintus

A Roadmap to Nonhematopoietic Stem Cell Based Therapeutics

A Roadmap to Nonhematopoietic Stem Cell Based Therapeutics Book
Author : Xiao-Dong Chen
Publisher : Academic Press
Release : 2018-08-31
ISBN : 0128119217
Language : En, Es, Fr & De

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Book Description :

A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent. Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies

Mesenchymal Stem Cells in Cancer Therapy

Mesenchymal Stem Cells in Cancer Therapy Book
Author : Khalid Shah
Publisher : Elsevier
Release : 2013-12-18
ISBN : 0124166652
Language : En, Es, Fr & De

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Book Description :

With the thorough understanding of stem cell biology and the advent of targeted therapeutics for cancer, stem cell-based therapeutic strategies are being increasingly explored for the treatment of various cancer types. Mesenchymal Stem Cells in Cancer Therapy sheds light on current stem cell based targeted therapies for cancer, by focusing on the application of mesenchymal stem cells (MSC) in various cancers with emphasis on a number of aspects that are critical to the success of future stem cell based therapies for cancer. Sections of this publication are devoted to developing stem cell based therapies for cancer with the main focus on tumoritrophic properties of stem cells, engineering targeted therapeutics, utilization of imaging techniques and the recent combination studies utilizing currently employed therapeutics with stem cells. Mesenchymal Stem Cells in Cancer Therapy informs readers about critical and cutting edge stem cell therapies for cancer and also enables them to appreciate the vast plain of unresolved questions in stem cell research for cancer therapeutics. Includes biological foundation on key sources of mesenchymal stem cells and the various ways they can be utilized to treat cancer. Provides examples of current MSC based cancer therapies and prospects for the future with insights from the leading lab on cancer cell therapies. Technically advanced topic written for widespread understanding for clinical and research audiences.

Principles of Tissue Engineering

Principles of Tissue Engineering Book
Author : Robert Lanza,Robert Langer,Joseph P. Vacanti,Anthony Atala
Publisher : Academic Press
Release : 2020-03-26
ISBN : 0128214015
Language : En, Es, Fr & De

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Book Description :

Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field. Organized into twenty-three parts, covering the basics of tissue growth and development, approaches to tissue and organ design, and a summary of current knowledge by organ system Introduces a new section and chapters on emerging technologies in the field Full-color presentation throughout

Adipose Derived Stem Cells ASCs for Tissue Engineering

Adipose Derived Stem Cells  ASCs  for Tissue Engineering Book
Author : Mathias Tremp,Daniel Eberli,Rita Gobet,Souzan Salemi,Tullio Sulser
Publisher : Unknown
Release : 2011
ISBN : 9789533076638
Language : En, Es, Fr & De

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Book Description :

Download Adipose Derived Stem Cells ASCs for Tissue Engineering book written by Mathias Tremp,Daniel Eberli,Rita Gobet,Souzan Salemi,Tullio Sulser, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biomaterials Science and Tissue Engineering

Biomaterials Science and Tissue Engineering Book
Author : Bikramjit Basu
Publisher : Cambridge University Press
Release : 2017-09-15
ISBN : 1108246230
Language : En, Es, Fr & De

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Book Description :

A comprehensive text in the field of biomaterials science and tissue engineering, covering fundamental principles and methods related to processing-microstructure-property linkages as applied to biomaterials science. Essential concepts and techniques of the cell biology are discussed in detail, with a focus quantitatively and qualitatively evaluating cell-material interaction. It gives detailed discussion on the processing, structure and properties of metals, ceramics and polymers, together with techniques and guidelines. Comprehensive coverage of in vitro and in vivo biocompatibility property evaluation of materials for bone, neural as well as cardiovascular tissue engineering applications, together with representative protocols. Supported by several multiple-choice questions, fill in the blanks, review questions, numerical problems and solutions to selected problems, this is an ideal text for undergraduate and graduate students in understanding fundamental concepts and the latest developments in the field of biomaterials science.

Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist Oncologist

Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist Oncologist Book
Author : Valerie I. Brown
Publisher : Springer
Release : 2017-12-22
ISBN : 3319631462
Language : En, Es, Fr & De

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Book Description :

This volume provides a comprehensive and state-of-the-art review on pediatric hematopoietic stem cell transplantation (HSCT). The book covers such topics as graft versus host disease (GVHD), HSC mobilization, stem cell selection, and HSCT-relevant laboratory assays and techniques. The text is specially formatted so that the scientific basis of HSCT and ethical considerations are integrated into the relevant clinical framework. Each chapter also includes diagrams, illustrations, and tables that summarize key points and concepts that can be used as a quick visual reference for the reader. Written by experts in the field, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist is a valuable resource on pediatric HSCT suited for pediatric hematologists-oncologists, fellows, advanced practitioners, clinical nurses, and other referring physicians.

Stem Cell Bioprocessing and Manufacturing

Stem Cell Bioprocessing and Manufacturing Book
Author : Joaquim M. S. Cabral,Cláudia Lobato da Silva,Maria Margarida Diogo
Publisher : MDPI
Release : 2021-01-20
ISBN : 3039430386
Language : En, Es, Fr & De

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Book Description :

The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the potential, and early products have shown the power of such therapies, there is an immediate and long-term need for expertise with the necessary skills to face the engineering and life science challenges before the predicted benefits in human healthcare can be realized. Specifically, there is a need for the development of bioprocess technology for the successful transfer of laboratory-based practice of stem cell and tissue culture to the clinic as therapeutics through the application of engineering principles and practices. This Special Issue of Bioengineering on Stem Cell Bioprocessing and Manufacturing addresses the central role in defining the engineering sciences of cell-based therapies, by bringing together contributions from worldwide experts on stem cell biology and engineering, bioreactor design and bioprocess development, scale-up, and manufacturing of stem cell-based therapies.

Tissue Engineering

Tissue Engineering Book
Author : Norbert Pallua,Christoph V. Suschek
Publisher : Springer Science & Business Media
Release : 2010-12-16
ISBN : 9783642028243
Language : En, Es, Fr & De

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Book Description :

Tissue engineering is a multidisciplinary field incorporating the principles of biology, chemistry, engineering, and medicine to create biological substitutes of native tissues for scientific research or clinical use. Specific applications of this technology include studies of tissue development and function, investigating drug response, and tissue repair and replacement. This area is rapidly becoming one of the most promising treatment options for patients suffering from tissue failure. This abundantly illustrated and well-structured guide serves as a reference for all clinicians and researchers dealing with tissue engineering issues in their daily practice.

The Principles and Practice of Antiaging Medicine for the Clinical Physician

The Principles and Practice of Antiaging Medicine for the Clinical Physician Book
Author : Vincent C. Giampapa
Publisher : River Publishers
Release : 2012-11
ISBN : 8792329438
Language : En, Es, Fr & De

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Book Description :

This book takes a whole new perspective concerning the approach to treating aging process. Most doctors feel they have no other options but to operate on the physical processes that occur as we grow older. Now, for the first time, there is another scientific approach that impacts on the causes of aging and not just on the effects. The basic principles and practice of anti-aging medicine and age management clearly and succinctly explains the solid scientific research behind doctor Giampapa's revolutionary theories, revealing that a key number of bio chemical processes at the cellular level can be clinically manipulated to successfully improve the physical signs of aging even without surgery. Dr. Giampapa gives the clinical dermatologist and plastic surgeon the knowledge and tools to successfully incorporate anti-aging medicine into their practice. These tools not only improve the longevity of their cosmetic procedures but markedly enhance the quality of life and health that patients can experience. Throughout the book a new concept of aging is built around preserving DNA function and replication. Treatment concepts are centered around: Controlling blood sugar levels and glycation; Inhibiting cellular inflammation; Supplying the correct combination of antioxidants; Improving gene regulation and methylation; Following a simple diet guide and exercise plan; Regulating age-related hormonal declines; Improving DNA repair and decreasing DNA damage. Containing hundreds of scientific medical references as a valuable resource for future investigation and information, this book is an essential addition to the cosmetic physicians library.

Principles of Gender Specific Medicine

Principles of Gender Specific Medicine Book
Author : Marianne J. Legato
Publisher : Academic Press
Release : 2017-05-15
ISBN : 0128035420
Language : En, Es, Fr & De

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Book Description :

The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols

Stem Cells and Human Diseases

Stem Cells and Human Diseases Book
Author : Rakesh K. Srivastava,Sharmila Shankar
Publisher : Springer Science & Business Media
Release : 2012-02-01
ISBN : 940072800X
Language : En, Es, Fr & De

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Book Description :

The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy. In addition, the role of cancer stem cells in cancer initiation, progression and drug resistance are discussed. The cell signaling pathways and microRNA regulating stem cell self-renewal, tissue homeostasis and drug resistance are also mentioned. Overall, these reviews will provide a new understanding of the influence of stem cells in tissue regeneration, disease regulation, therapy and drug resistance in several human diseases.