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Sarcopenia

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Sarcopenia

Sarcopenia Book
Author : Kunihiro Sakuma
Publisher : Elsevier
Release : 2021-07-22
ISBN : 0128226579
Language : En, Es, Fr & De

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Book Description :

Sarcopenia: Molecular Mechanism and Treatment Strategies provides answers and guidance on a disease that has serious health consequences in terms of fractures, frailty, disability and diminished quality of life. Written by experts around the world, this book is for all those that care for aging populations. As the global population ages, sarcopenia remains a therapeutic challenge and major public health concern. Difficulties in defining sarcopenia as a clinical phenotype remain and have hindered treatment. Covers physical, dietary and pharmacological strategies to maintain adequate muscle mass to ensure healthy aging Provides a complete and up-to-date reference on molecular mechanisms of sarcopenia Presents a clear definition of sarcopenia, along with the latest research in one volume

Sarcopenia

Sarcopenia Book
Author : Alfonso J. Cruz-Jentoft,John E. Morley
Publisher : John Wiley & Sons
Release : 2021-06-15
ISBN : 1119597900
Language : En, Es, Fr & De

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Book Description :

SARCOPENIA An in-depth examination of sarcopenia’s underexplored yet widespread impact within the field of gerontology Sarcopenia is common in older men and women, and yet awareness of its clinical relevance is still relatively low. Only formally included in the International Classification of Diseases in 2016, the condition may impact societies with serious health-related and financial consequences unless consistent, effective methods of identification and management are adopted. This second edition of Sarcopenia provides geriatricians and other healthcare professionals with a revised and expanded examination of this understudied and underdiagnosed condition. Edited by two leading authorities on the subject, it covers the epidemiology and diagnosis of sarcopenia, as well as treatment options and possible prevention strategies. Eight newly written chapters build upon existing knowledge with fresh data on topics including sarcopenia’s biomarkers and its impact on the healthcare economy. This important text: Defines sarcopenia and explains its clinical relevance Covers all recent scientific evidence Outlines treatment options Considers prevention strategies Discusses sarcopenia as a public health priority Features eight new chapters covering topics such as sarcopenia’s clinical management, its biomarkers, and its financial impact Containing vital information for clinicians and other professionals working in geriatric care, nursing homes, nutrition, cancer, endocrinology, surgery, sports medicine and many other specialties, Sarcopenia, second edition, is a groundbreaking and essential new resource.

Sarcopenia

Sarcopenia Book
Author : Dominique Meynial-Denis
Publisher : CRC Press
Release : 2019-11-20
ISBN : 0429531974
Language : En, Es, Fr & De

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Book Description :

Sarcopenia: Molecular, Cellular, and Nutritional Aspects describes the progressive loss of skeletal muscle mass and strength, defined by Rosenberg in 1997 as a hallmark of aging and referred to as “sarcopenia.” As life expectancy continues to increase worldwide, sarcopenia has become a major public health issue. The condition worsens in the presence of chronic diseases accelerating its progression. Sarcopenia is not considered to be “a process of normative aging” but according to the International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM), as a disease. As sarcopenia is an ineluctable process, prevention and management are the only options to promote healthy aging; these actions should perhaps be taken during youth. Included in this book: · Features essential information on sarcopenia, its current definition, and molecular and cellular aspects of this disease · Discusses the development of physical frailty, a complication of sarcopenia, and predicts its occurrence in the older population · Presents alterations in muscle protein turnover and mitochondrial dysfunction in the aging process · Provides data on the negative involvement of sarcopenia in certain chronic diseases · Describes presbyphagia or age-related changes in the swallowing mechanism in older people · Details possible strategies to combat muscle wasting in healthy older adults and their limits This book features information collected from pioneers or experts on human aging from around the globe, including Europe, Brazil, Canada, Japan and the United States. It is a valuable source of information for nutritional scientists, medical doctors, sports scientists, food scientists, dietitians, students in these fields, and for anyone interested in nutrition. We hope this book provides a better understanding of sarcopenia which inevitably occurs with aging without weight loss. Moreover, this book will supply information outlining strategies to prevent or limit muscle wasting due to normal aging in order to promote successful aging.

Sarcopenia Age Related Muscle Wasting and Weakness

Sarcopenia     Age Related Muscle Wasting and Weakness Book
Author : Gordon S. Lynch
Publisher : Springer Science & Business Media
Release : 2010-11-30
ISBN : 9048197139
Language : En, Es, Fr & De

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Book Description :

Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. There is an urgent need to better understand the neuromuscular mechanisms underlying age-related muscle wasting and to develop therapeutic strategies that can attenuate, prevent, or ultimately reverse sarcopenia. Significant research and development in academic and research institutions and in pharmaceutical companies is being directed to sarcopenia and to related health issues in order to develop and evaluate novel therapeutics. This book provides the latest information on sarcopenia from leading international researchers studying the cellular and molecular mechanisms underlying age-related changes in skeletal muscle and identifies strategies to combat sarcopenia and related muscle wasting conditions and neuromuscular disorders. The book provides a vital resource for researchers and practitioners alike, with information relevant to gerontologists, geriatricians, sports medicine physicians, physiologists, neuroscientists, cell biologists, endocrinologists, physical therapists, allied health and musculoskeletal practitioners, strength and conditioning specialists, athletic trainers, and students of the medical and biomedical sciences.

Sarcopenia

Sarcopenia Book
Author : Nicola Veronese,Charlotte Beaudart,Shaun Sabico
Publisher : Springer Nature
Release : 2021-08-27
ISBN : 3030800385
Language : En, Es, Fr & De

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Book Description :

This book offers a concise and updated guide for all readers (physicians and non-physicians) interested in gaining a comprehensive and precise understanding of sarcopenia. Over the last several years, sarcopenia has increasingly developed from being a concept known only in research settings to one that is commonly explored in journals and scientific meetings for various disciplines, such as geriatrics, rheumatology and rehabilitation medicine. Thus, all domains of sarcopenia, from molecular aspects to clinical management, represent highly active areas of research and clinical practice for health professionals in a variety of fields, including geriatric medicine, nutrition, and epidemiology. Despite being a relatively new concept in medicine, sarcopenia is increasingly being recognized as an important determinant of other health conditions, including mortality and disability. This book, written by experts from around the globe, covers several core aspects of sarcopenia management, from molecular mechanisms to genetics, epidemiology, diagnosis and finally treatment, including the clinical impact of sarcopenia as a risk factor, the known genetic and molecular aspects that can aid in predicting sarcopenia, and selected treatment and therapy concepts, including indications for nutrition and physical exercise. Sharing data from the latest studies, it will be of considerable interest not only for geriatricians, but also for a wide range of other readers.

Frailty and Sarcopenia

Frailty and Sarcopenia Book
Author : Yannis Dionyssiotis
Publisher : BoD – Books on Demand
Release : 2017-08-30
ISBN : 9535134833
Language : En, Es, Fr & De

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Book Description :

Frailty is considered a multisystem impairment that makes an individual vulnerable to external or internal stressors. Sarcopenia, the age-dependent loss of muscle mass and function, is proposed as the biological substrate and the pathway whereby the consequences of physical frailty develop. These syndromes are associated with a negative impact in quality of life and can lead to the occurrence of disability, institutionalization, and even mortality. The book focuses upon all the related aspects of frailty and sarcopenia and the new advancements in the related treatments including complex issues and research. It includes high-quality chapters in all related aspects for the syndromes of sarcopenia and frailty, which adversely affect the function and overall effectiveness of the musculoskeletal system and interventions to promote rehabilitation.

Clinical Nutrition and Aging

Clinical Nutrition and Aging Book
Author : Chad Cox
Publisher : CRC Press
Release : 2017-10-02
ISBN : 1315361957
Language : En, Es, Fr & De

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Book Description :

This title includes a number of Open Access chapters. Sarcopenia—the loss of muscle mass and strength that occurs with advancing age—is a major health challenge, particularly in North America, Europe, and Japan, which have large aging populations. This compendium volume is a valuable addition to the existing literature, providing state-of-the-art information on the most effective prevention and treatment options. Included are research articles on nutrition management and the prevention of sarcopenia; protein therapy for sarcopenia; effect of exercise on sarcopenia; and other therapeutic strategies, including antioxidants and steroids.

Sarcopenia

Sarcopenia Book
Author : Alfonso J. Cruz-Jentoft,John E. Morley
Publisher : John Wiley & Sons
Release : 2021-07-06
ISBN : 1119597870
Language : En, Es, Fr & De

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Book Description :

SARCOPENIA An in-depth examination of sarcopenia’s underexplored yet widespread impact within the field of gerontology Sarcopenia is common in older men and women, and yet awareness of its clinical relevance is still relatively low. Only formally included in the International Classification of Diseases in 2016, the condition may impact societies with serious health-related and financial consequences unless consistent, effective methods of identification and management are adopted. This second edition of Sarcopenia provides geriatricians and other healthcare professionals with a revised and expanded examination of this understudied and underdiagnosed condition. Edited by two leading authorities on the subject, it covers the epidemiology and diagnosis of sarcopenia, as well as treatment options and possible prevention strategies. Eight newly written chapters build upon existing knowledge with fresh data on topics including sarcopenia’s biomarkers and its impact on the healthcare economy. This important text: Defines sarcopenia and explains its clinical relevance Covers all recent scientific evidence Outlines treatment options Considers prevention strategies Discusses sarcopenia as a public health priority Features eight new chapters covering topics such as sarcopenia’s clinical management, its biomarkers, and its financial impact Containing vital information for clinicians and other professionals working in geriatric care, nursing homes, nutrition, cancer, endocrinology, surgery, sports medicine and many other specialties, Sarcopenia, second edition, is a groundbreaking and essential new resource.

Sarcopenia

Sarcopenia Book
Author : Dominique Meynial-Denis
Publisher : CRC Press
Release : 2019-11-20
ISBN : 1498765149
Language : En, Es, Fr & De

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Book Description :

Sarcopenia: Molecular, Cellular, and Nutritional Aspects describes the progressive loss of skeletal muscle mass and strength, defined by Rosenberg in 1997 as a hallmark of aging and referred to as “sarcopenia.” As life expectancy continues to increase worldwide, sarcopenia has become a major public health issue. The condition worsens in the presence of chronic diseases accelerating its progression. Sarcopenia is not considered to be “a process of normative aging” but according to the International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM), as a disease. As sarcopenia is an ineluctable process, prevention and management are the only options to promote healthy aging; these actions should perhaps be taken during youth. Included in this book: · Features essential information on sarcopenia, its current definition, and molecular and cellular aspects of this disease · Discusses the development of physical frailty, a complication of sarcopenia, and predicts its occurrence in the older population · Presents alterations in muscle protein turnover and mitochondrial dysfunction in the aging process · Provides data on the negative involvement of sarcopenia in certain chronic diseases · Describes presbyphagia or age-related changes in the swallowing mechanism in older people · Details possible strategies to combat muscle wasting in healthy older adults and their limits This book features information collected from pioneers or experts on human aging from around the globe, including Europe, Brazil, Canada, Japan and the United States. It is a valuable source of information for nutritional scientists, medical doctors, sports scientists, food scientists, dietitians, students in these fields, and for anyone interested in nutrition. We hope this book provides a better understanding of sarcopenia which inevitably occurs with aging without weight loss. Moreover, this book will supply information outlining strategies to prevent or limit muscle wasting due to normal aging in order to promote successful aging.

Fragility Fracture Nursing

Fragility Fracture Nursing Book
Author : Karen Hertz,Julie Santy-Tomlinson
Publisher : Springer
Release : 2018-06-15
ISBN : 3319766813
Language : En, Es, Fr & De

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Book Description :

This open access book aims to provide a comprehensive but practical overview of the knowledge required for the assessment and management of the older adult with or at risk of fragility fracture. It considers this from the perspectives of all of the settings in which this group of patients receive nursing care. Globally, a fragility fracture is estimated to occur every 3 seconds. This amounts to 25 000 fractures per day or 9 million per year. The financial costs are reported to be: 32 billion EUR per year in Europe and 20 billon USD in the United States. As the population of China ages, the cost of hip fracture care there is likely to reach 1.25 billion USD by 2020 and 265 billion by 2050 (International Osteoporosis Foundation 2016). Consequently, the need for nursing for patients with fragility fracture across the world is immense. Fragility fracture is one of the foremost challenges for health care providers, and the impact of each one of those expected 9 million hip fractures is significant pain, disability, reduced quality of life, loss of independence and decreased life expectancy. There is a need for coordinated, multi-disciplinary models of care for secondary fracture prevention based on the increasing evidence that such models make a difference. There is also a need to promote and facilitate high quality, evidence-based effective care to those who suffer a fragility fracture with a focus on the best outcomes for recovery, rehabilitation and secondary prevention of further fracture. The care community has to understand better the experience of fragility fracture from the perspective of the patient so that direct improvements in care can be based on the perspectives of the users. This book supports these needs by providing a comprehensive approach to nursing practice in fragility fracture care.

Sarcopenia Frailty and Nutrition in Liver Diseases

Sarcopenia  Frailty and Nutrition in Liver Diseases Book
Author : Speranta Iacob,Susanne Beckebaum,Dan Lucian Dumitrascu,Liana Gheorghe
Publisher : Frontiers Media SA
Release : 2022-07-01
ISBN : 2889764710
Language : En, Es, Fr & De

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Book Description :

Download Sarcopenia Frailty and Nutrition in Liver Diseases book written by Speranta Iacob,Susanne Beckebaum,Dan Lucian Dumitrascu,Liana Gheorghe, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Reducing the Burden of Age related Disease in relation to Osteoporosis Sarcopenia and Osteosarcopenia

Reducing the Burden of Age related Disease in relation to Osteoporosis  Sarcopenia and Osteosarcopenia Book
Author : Bagher Larijani,An Pan,Farshad Farzadfar,Ramin Heshmat,Arshed Ali Quyyumi,Afshin Ostovar
Publisher : Frontiers Media SA
Release : 2022-05-09
ISBN : 2889761622
Language : En, Es, Fr & De

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Book Description :

Download Reducing the Burden of Age related Disease in relation to Osteoporosis Sarcopenia and Osteosarcopenia book written by Bagher Larijani,An Pan,Farshad Farzadfar,Ramin Heshmat,Arshed Ali Quyyumi,Afshin Ostovar, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Reverse Sarcopenia

Reverse Sarcopenia Book
Author : Joseph Tieri
Publisher : Simon and Schuster
Release : 2019-07-26
ISBN : 1612439187
Language : En, Es, Fr & De

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Book Description :

Take control of your physical and brain health with low-level strength training We all know that we lose muscle mass as we age. But did you know that sarcopenic obesity (a.k.a. being “skinny fat”) is linked to increasing your risk of developing dementia and/or Alzheimer’s? Not only is losing muscle bad for your body, it’s also bad for your brain. Don’t let muscle deterioration negatively affect your future. It’s time to take your physical and brain health into your own hands with strength training. This book is full of tips, techniques, and easy-to-follow strength-training routines to fight sarcopenia. From beginners to those already comfortable using weights, this book has solutions for everyone. Lose fat, improve muscle tone, and strengthen bones while guarding against sarcopenia and its negative impact on your body and your brain. This book makes it easy to regain the muscle mass you need to live a healthier and longer life.

Prevention and Treatment of Sarcopenia

Prevention and Treatment of Sarcopenia Book
Author : Gianluca Testa
Publisher : Mdpi AG
Release : 2021-11-19
ISBN : 9783036515366
Language : En, Es, Fr & De

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Book Description :

Sarcopenia represents the decline in skeletal muscle mass and function with age, characterized by the muscle fiber's quality, strength, muscle endurance, and metabolic ability decreasing, as well as the fat and connective tissue growing. Reduction of muscle strength with aging leads to loss of functional capacity, causing disability, mortality, and other adverse health outcomes. Because of the increase of the proportion of elderly in the population, sarcopenia-related morbidity will become an increasing area of health care resource utilization. Diagnostic screening consists of individuation of body composition, assessed by DEXA, anthropometry, bioelectrical impedance, MRI, or CT scan. Management is possible with resistance training exercise and vibration therapy, nutritional supplements, and pharmacological treatment. The book includes articles from different nationalities, treating the experimental and medical applications of sarcopenia. The consequences of sarcopenia in frailty are treated in relation to other associated pathologies or lesions, as femoral neck fractures and hepatocellular carcinoma.

Oxford Textbook of Geriatric Medicine

Oxford Textbook of Geriatric Medicine Book
Author : Jean-Pierre Michel,Jeremy D. Walston
Publisher : Oxford University Press
Release : 2017-12-14
ISBN : 0198701594
Language : En, Es, Fr & De

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Book Description :

Over the past two decades there has been a marked change in global age demographics, with the number of over-60s increasing by 82% and the number of centenarians by 715%. This new-found longevity is testament to the success of recent advances in medicine, but poses significant challenges to multiple areas of health care concerning older patients. Building upon its predecessor's reputation as the definitive resource on the subject, this new edition of the Oxford Textbook of Geriatric Medicine offers a comprehensive and multinational examination of the field. Fully revised to reflect the current state of geriatric medicine, it examines the medical and scientific basis of clinical issues, as well as the ethical, legal, and socio-economic concerns for healthcare policy and systems. Over 170 chapters are broken up into 16 key sections, covering topics ranging from policy and key concepts through to infection, cancer, palliative medicine, and healthy ageing. New material includes focus on the evolving concepts of malnutrition, sarcopenia, frailty, and related geriatric syndromes and integration of geriatric principles from public health, primary and specialized care, and transitional stages from home to emergency, medicine and surgery, rehabilitation, and long term care. The Oxford Textbook of Geriatric Medicine brings together specialists from across the globe to provide every physician involved in the care of older patients with a comprehensive resource on all the clinical problems they are likely to encounter, as well as on related psychological, philosophical, and social issues.

Osteosarcopenia Bone Muscle and Fat Interactions

Osteosarcopenia  Bone  Muscle and Fat Interactions Book
Author : Gustavo Duque
Publisher : Springer Nature
Release : 2019-11-06
ISBN : 3030258904
Language : En, Es, Fr & De

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Book Description :

This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap. This overlap between osteoporosis and sarcopenia has major negative effects not only on our older adults but also on health systems worldwide. Readers will find a highly translational approach that starts with a summary of recent discoveries on stem cells biology, muscle and bone interactions – including the role of local bone and muscle fat – followed by comprehensive reviews on myokines (i.e. myostatin), osteokines (i.e. osteocalcin) and adipokines (i.e. interleukins) as major players and determinants of bone and muscle loss with aging. In addition, the role of sex steroids (i.e. estrogens, androgens), and calciotropic hormones (i.e. parathyroid hormone, vitamin D) in the pathogenesis of this syndrome is also reviewed. Moreover, using practical diagnostic and therapeutic tips, this book summarizes the clinical characteristics of osteosarcopenic patients thus facilitating the diagnosis and treatment of this syndrome in clinical practice. Finally, the book presents the case for the Falls and Fractures Clinic as the optimal model of care for this syndrome, aimed to avoid fragmentation and optimize osteosarcopenia care, and simultaneously prevent falls and fractures in older persons. This book offers relevant information on the mechanisms of osteosarcopenia, and a practical guide on how to identify and treat this geriatric syndrome and its adverse outcomes, which are dramatically affecting our aging population. The work is written by leaders in the field and is especially suited not only to any researcher in the musculoskeletal arena but also to medical specialists and allied health professionals involved in the care of older persons.

Nutritional Aspects of Kidney Disease

Nutritional Aspects of Kidney Disease Book
Author : Alice Sabatino,Carla Maria Avesani
Publisher : Frontiers Media SA
Release : 2022-01-10
ISBN : 2889740056
Language : En, Es, Fr & De

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Book Description :

Download Nutritional Aspects of Kidney Disease book written by Alice Sabatino,Carla Maria Avesani, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Plasticity of Skeletal Muscle

The Plasticity of Skeletal Muscle Book
Author : Kunihiro Sakuma
Publisher : Springer
Release : 2017-03-01
ISBN : 9811032920
Language : En, Es, Fr & De

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Book Description :

This book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis. The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It also explains the roles of biological mediators such as PGC-1, transient receptor potential cation channels (TRPC), and AMPK in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome biogenesis, and redox regulation of mechanotransduction to modulate skeletal muscle mass are also covered. It is an essential resource for physicians, researchers, post-docs as well as graduate students in the field of sports science including rehabilitation therapy, exercise physiology, exercise biochemistry, and molecular biology dealing with skeletal muscle.

Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy A Translational Approach

Pathophysiological Mechanisms of Sarcopenia in Aging and in Muscular Dystrophy  A Translational Approach Book
Author : Luciano Merlini,Paolo Bonaldo,Emanuele Marzetti
Publisher : Frontiers Media SA
Release : 2016-01-18
ISBN : 2889196844
Language : En, Es, Fr & De

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Book Description :

Loss of muscle mass and increased fibrosis characterize both sarcopenia of aging and muscular dystrophy. Research is increasingly showing that these two conditions also share several pathophysiological mechanisms, including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and abnormal regulation of signaling and stress response pathways. This Research Topic will cover several mechanisms involved in aging and dystrophic sarcopenia and explore the therapeutic potential of various strategies for intervention.

Muscle Atrophy

Muscle Atrophy Book
Author : Junjie Xiao
Publisher : Springer
Release : 2018-11-02
ISBN : 9811314357
Language : En, Es, Fr & De

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Book Description :

The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book’s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology.