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Research In The Biomedical Sciences

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Research in the Biomedical Sciences

Research in the Biomedical Sciences Book
Author : Michael Curtis,Michael Williams
Publisher : Academic Press
Release : 2017-06-01
ISBN : 9780128047255
Language : En, Es, Fr & De

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Book Description :

Research in the Biomedical Sciences: Transparent and Reproducible documents the widespread concerns related to reproducibility in biomedical research and provides a best practices guide to effective and transparent hypothesis generation, experimental design, reagent standardization (including validation and authentication), statistical analysis, and data reporting. The book addresses issues in the perceived value of the existing peer review process and calls for the need for improved transparency in data reporting. It reflects new guidelines for publication that include manuscript checklists, replication/reproducibility initiatives, and the potential consequences for the biomedical research community and societal health and well-being if training, mentoring, and funding of new generations of researchers and incentives for publications are not improved. This book offers real world examples, insights, and solutions to provide a thought-provoking and timely resource for all those learning about, or engaged in, performing and supervising research across the biomedical sciences. Provides a "big picture" perspective that includes the scope of the replicability issue and covers initiatives that have the potential to act as effective solutions Offers real world research context for transparent, replicable experimental design and execution and reporting of biomedical research with the potential to address aspects of the translational gap in drug discovery Highlights the importance of reproducibility and the necessary changes in biomedical and pharmaceutical research training and incentives to ensure sustainability

Research Training in the Biomedical Behavioral and Clinical Research Sciences

Research Training in the Biomedical  Behavioral  and Clinical Research Sciences Book
Author : National Research Council,Policy and Global Affairs,Board on Higher Education and Workforce,Committee to Study the National Needs for Biomedical, Behavioral, and Clinical Research Personnel
Publisher : National Academies Press
Release : 2011-03-28
ISBN : 0309159652
Language : En, Es, Fr & De

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Book Description :

Comprehensive research and a highly-trained workforce are essential for the improvement of health and health care both nationally and internationally. During the past 40 years the National Research Services Award (NRSA) Program has played a large role in training the workforce responsible for dramatic advances in the understanding of various diseases and new insights that have led to more effective and targeted therapies. In spite of this program, the difficulty obtaining jobs after the postdoc period has discouraged many domestic students from pursuing graduate postdoc training. In the United States, more than 50 percent of the postdoc workforce is made up of individuals who obtained their Ph.D.s from other countries. Indeed, one can make a strong argument that the influx of highly trained and creative foreigners has contributed greatly to U.S. science over the past 70 years. Research Training in the Biomedical, Behavioral, and Clinical Research Sciences discusses a number of important issues, including: the job prospects for postdocs completing their training; questions about the continued supply of international postdocs in an increasingly competitive world; the need for equal, excellent training for all graduate students who receive NIH funding; and the need to increase the diversity of trainees. The book recommends improvements in minority recruiting, more rigorous and extensive training in the responsible conduct of research and ethics, increased emphasis on career development, more attention to outcomes, and the requirement for incorporating more quantitative thinking in the biomedical curriculum.

Reporting and Publishing Research in the Biomedical Sciences

Reporting and Publishing Research in the Biomedical Sciences Book
Author : Peush Sahni,Rakesh Aggarwal
Publisher : Springer
Release : 2018-08-21
ISBN : 9811070628
Language : En, Es, Fr & De

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Book Description :

This book eases the task of converting research work into a manuscript, and covers the recent developments in publishing that often stump budding researchers. Few researchers in the biomedical sciences are trained in the essential skills of reporting their results, and they seek help in writing a paper that will be acceptable for publication in the ‘right’ journal, and in presenting their results ‘effectively’ at a meeting. As well as covering the basic aspects of preparing manuscripts for publication, the book discusses best practices and issues relating to the publication of biomedical research, including topics such as peer-review, authorship, plagiarism, conflicts of interest, publication misconduct, electronic publishing and open-access journals. With more than two decades of experience in conducting workshops on writing scientific papers, the editors have brought together the expertise of 29 authors from seven countries to produce this one-stop guide to publishing research in biomedical sciences. This book is intended for young researchers who are beginning their careers and wish to hone their skills and understand the rigors of research writing and publishing.

The Biomedical Sciences in Society

The Biomedical Sciences in Society Book
Author : Iain Crinson
Publisher : Springer Nature
Release : 2021-03-02
ISBN : 9811595232
Language : En, Es, Fr & De

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Book Description :

This textbook provides a comprehensive introduction to the interdisciplinary field of the Social Studies of Science and Technology (SSST). Over the past two decades, the biomedical sciences have transformed our understanding of the relationship between the social and natural worlds, while its ‘promissory visions’ are seen to offer extraordinary opportunities for economic and social development. But alongside these scientific innovations have emerged new, and frequently unanticipated social, political, bioethical, and legal dilemmas and challenges. This cutting-edge text explores ‘post-genomic’ developments in the field of pharmacogenomics and the prospects for a new ‘precision’ or personalised medicine; the potential of environmental epigenetics to reconfigure the boundaries of the social and natural worlds; the emergence of an array of ‘neuro-disciplines’, seeking to identify the neural basis of a whole range of social and economic behaviours; and the challenges of constructing a coherent and robust governance framework for the conduct of biomedical science research and innovation, responsive to the social and health needs of the whole population.

Advancing the Nation s Health Needs

Advancing the Nation s Health Needs Book
Author : National Research Council,Policy and Global Affairs,Board on Higher Education and Workforce,Committee for Monitoring the Nation's Changing Needs for Biomedical, Behavioral, and Clinical Personnel
Publisher : National Academies Press
Release : 2005-08-13
ISBN : 0309094275
Language : En, Es, Fr & De

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Book Description :

This report is the twelfth assessment of the National Institutes of Health National Research Service Awards program. The research training needs of the country in basic biomedical, clinical, and behavioral and social sciences are considered. Also included are the training needs of oral health, nursing, and health services research. The report has been broadly constructed to take into account the rapidly evolving national and international health care needs. The past and present are analyzed, and predictions with regard to future needs are presented.

A Guide to Methods in the Biomedical Sciences

A Guide to Methods in the Biomedical Sciences Book
Author : Ronald B. Corley
Publisher : Springer Science & Business Media
Release : 2006-01-16
ISBN : 0387228454
Language : En, Es, Fr & De

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Book Description :

Thousands of methods have been developed in the various biomedical disciplines, and those covered in this book represent the basic, essential and most widely used methods in several different disciplines.

Interpreting Biomedical Science

Interpreting Biomedical Science Book
Author : Ülo Maiväli
Publisher : Academic Press
Release : 2015-06-12
ISBN : 0124199569
Language : En, Es, Fr & De

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Book Description :

Interpreting Biomedical Science: Experiment, Evidence, and Belief discusses what can go wrong in biological science, providing an unbiased view and cohesive understanding of scientific methods, statistics, data interpretation, and scientific ethics that are illustrated with practical examples and real-life applications. Casting a wide net, the reader is exposed to scientific problems and solutions through informed perspectives from history, philosophy, sociology, and the social psychology of science. The book shows the differences and similarities between disciplines and different eras and illustrates the concept that while sound methodology is necessary for the progress of science, we cannot succeed without a right culture of doing things. Features theoretical concepts accompanied by examples from biological literature Contains an introduction to various methods, with an emphasis on statistical hypothesis testing Presents a clear argument that ties the motivations and ethics of individual scientists to the success of their science Provides recommendations on how to safeguard against scientific misconduct, fraud, and retractions Arms young scientists with practical knowledge that they can use every day

Large Scale Biomedical Science

Large Scale Biomedical Science Book
Author : National Research Council,Division on Earth and Life Studies,Institute of Medicine,National Cancer Policy Board,Committee on Large-Scale Science and Cancer Research
Publisher : National Academies Press
Release : 2003-07-19
ISBN : 0309089123
Language : En, Es, Fr & De

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Book Description :

The nature of biomedical research has been evolving in recent years. Technological advances that make it easier to study the vast complexity of biological systems have led to the initiation of projects with a larger scale and scope. In many cases, these large-scale analyses may be the most efficient and effective way to extract functional information from complex biological systems. Large-Scale Biomedical Science: Exploring Strategies for Research looks at the role of these new large-scale projects in the biomedical sciences. Though written by the National Academies' Cancer Policy Board, this book addresses implications of large-scale science extending far beyond cancer research. It also identifies obstacles to the implementation of these projects, and makes recommendations to improve the process. The ultimate goal of biomedical research is to advance knowledge and provide useful innovations to society. Determining the best and most efficient method for accomplishing that goal, however, is a continuing and evolving challenge. The recommendations presented in Large-Scale Biomedical Science are intended to facilitate a more open, inclusive, and accountable approach to large-scale biomedical research, which in turn will maximize progress in understanding and controlling human disease.

Current Topics in Biomedical Research

Current Topics in Biomedical Research Book
Author : Reinhard Kurth,Walther K. Schwerdtfeger
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642770797
Language : En, Es, Fr & De

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Book Description :

A select group of highly renowned scientists - among them four Nobel Prize Winners - have been asked to summarize significant developments of their ownrecent research in the life sciences at a workshop organized on the occasionof the opening of the new Paul-Ehrlich-Institut in Langen near Frankfurt/ Main. They do this in a comparative fashion evaluating similar achievements in adjacent fields. Their intellectual state-of-the-art analysis and fascinating outlook on future perspectives provides exciting and stimulating reading. The authors address areas in virology, immunology, oncology and evolution. Intelligent design of vaccines and other immunologial drugs, virus evolution and viruses as nature's engineers, pathology of chronic autoimmune and central nervous system diseases and the biology of mammary cancer belong to the topics discussed. A book easy to read for scientists, doctors and students interested in rapidly developing fields in the life sciences.

A Practical Guide to Biomedical Research

A Practical Guide to Biomedical Research Book
Author : Peter Agger,Robert S. Stephenson,J. Michael Hasenkam
Publisher : Springer
Release : 2017-10-27
ISBN : 3319635824
Language : En, Es, Fr & De

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Book Description :

This book advises and supports novice researchers in taking their first steps into the world of scientific research. Through practical tips and tricks presented in a clear, concise and step-wise manner, the book describes the entire research process from idea to publication. It also gives the reader insight into the vast opportunities a research career can provide. The books target demographic is aspiring researchers within the biomedical professions, be it medical students, young doctors, nurses, engineers, physiotherapists etc. The book will help aspirational inexperienced researchers turn their intentions into actions, providing crucial guidance for successful entry into the field of biomedical research.

Planning a Career in Biomedical and Life Sciences

Planning a Career in Biomedical and Life Sciences Book
Author : Avrum I. Gotlieb
Publisher : Academic Press
Release : 2014-12-08
ISBN : 0128025700
Language : En, Es, Fr & De

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Book Description :

Planning a Career in Biomedical and Life Sciences presents useful information, insights, and tips to those pursuing a career in the biomedical and life sciences. The book focuses on making educated choices during schooling, training, and job searching in both the academic and non-academic sectors. The premise of Planning a Career in Biomedical and Life Sciences is that by understanding the full path of a career in either the biomedical or life science fields, you can proactively plan your career, recognize any opportunities that present themselves, and be well prepared to address important aspects of your own professional development. Topics include choosing your training path, selecting the best supervisor/mentor, and negotiating a job offer. Provides strategies on evaluating biomedical and life sciences education and professional development opportunities in a thorough and systematic fashion. Discusses possible pitfalls and offers insight into how to navigate them successfully at various points of a scientist’s career. Offers valuable advice on how to make the best choices for yourself at any stage in your career.

Career Advice for Young Scientists in Biomedical Research

Career Advice for Young Scientists in Biomedical Research Book
Author : Béla Z. Schmidt
Publisher : Springer
Release : 2021-11-01
ISBN : 9783030855703
Language : En, Es, Fr & De

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Book Description :

Pursuing a career in biomedical research can be daunting, considering the stiffer competition and uncertain career prospects in academia. This book summarizes career advice gathered during in-depth interviews with 106 biomedical scientists who lead their own laboratories. The participating principal investigators are from 44 research institutions in 11 countries. This book is unique in that it provides a glimpse into the mindset of principal investigators. Here, the reader will learn about common thought patterns and values, as well as the range of opinions and ways of thinking to be found among a large group of active principal investigators – without having to read more than a hundred individual autobiographies. The book will benefit all PhD students who want to learn more about their supervisor’s mindset in order to successfully complete their projects. It can help freshly graduated PhDs planning to pursue an academic career, and MDs contemplating a career in research, to decide whether they truly want to embark on this path. Lastly, it can offer young principal investigators a source of inspiration on how to succeed and achieve their goals.

Today s Curiosity is Tomorrow s Cure

Today s Curiosity is Tomorrow s Cure Book
Author : Steve Caplan
Publisher : CRC Press
Release : 2021-11-10
ISBN : 1000471004
Language : En, Es, Fr & De

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Book Description :

Basic curiosity-driven biomedical science has delivered many of today’s most significant medical advances. This book provides clearly explained examples from recent biomedical history and includes convincing arguments for sustaining a robust portfolio of basic research. Intended as an engaging read, which will delight undergraduate and graduate students, as well as scientific researchers, it is full-throated advocacy of basic science. Illustrations and examples include the discoveries of penicillin and insulin, and the breakthrough elucidation of the genetic code. Providing both compelling rationale in support of basic science, and a fascinating look through the history of modern biomedical research, this book highlights with stirring examples why basic biomedical research is so important, and how so many key advances in medicine are derived from basic research. The book also offers a rationale for scientific inquiry and a broader understanding of the history of modern biomedical research missing from today’s classrooms. Key Features 1) Provides clear explanations of great scientific discoveries 2) Illustrates connections between basic research findings and modern medicine 3) Includes compelling graphics/diagrams/illustrations 4) Accessible to the general public 5) Offers background for more specialized readers, including researchers as well as those with advanced degrees. Related Titles Staddon, J. Scientific Method: How Science Works, Fails to Work, and Pretends to Work (ISBN 978-1-1382-9536-0) Helliwell, J. R. Skills for Scientific Life (ISBN 978-1-4987-6875-7) MacRitchie, F. Scientific Research as a Career (ISBN 978-1-4398-6965-9)

Enhancing the Vitality of the National Institutes of Health

Enhancing the Vitality of the National Institutes of Health Book
Author : National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Organizational Structure of the National Institutes of Health
Publisher : National Academies Press
Release : 2003-07-29
ISBN : 0309167116
Language : En, Es, Fr & De

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Book Description :

The report says that important organizational changes are needed at the National Institutes of Health to ensure the agency meets future challenges effectively. In particular, the report advises NIH to devote additional resources to innovative interdisciplinary research that reflects its strategic objectives and cuts across all agency's institutes and centers. The report recommends that Congress should establish a formal process for determining how specific proposals for changes in the number of NIH agencies and centers should be addressed.

Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research Book
Author : P. Michael Conn
Publisher : Springer Science & Business Media
Release : 2008-03-07
ISBN : 1597452858
Language : En, Es, Fr & De

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Book Description :

The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

The Next Generation of Biomedical and Behavioral Sciences Researchers

The Next Generation of Biomedical and Behavioral Sciences Researchers Book
Author : National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Board on Higher Education and Workforce,Committee on the Next Generation Initiative
Publisher : National Academies Press
Release : 2018-07-18
ISBN : 0309471370
Language : En, Es, Fr & De

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Book Description :

Since the end of the Second World War, the United States has developed the world's preeminent system for biomedical research, one that has given rise to revolutionary medical advances as well as a dynamic and innovative business sector generating high-quality jobs and powering economic output and exports for the U.S. economy. However, there is a growing concern that the biomedical research enterprise is beset by several core challenges that undercut its vitality, promise, and productivity and that could diminish its critical role in the nation's health and innovation in the biomedical industry. Among the most salient of these challenges is the gulf between the burgeoning number of scientists qualified to participate in this system as academic researchers and the elusive opportunities to establish long-term research careers in academia. The patchwork of measures to address the challenges facing young scientists that has emerged over the years has allowed the U.S. biomedical enterprise to continue to make significant scientific and medical advances. These measures, however, have not resolved the structural vulnerabilities in the system, and in some cases come at a great opportunity cost for young scientists. These unresolved issues could diminish the nation's ability to recruit the best minds from all sectors of the U.S. population to careers in biomedical research and raise concerns about a system that may favor increasingly conservative research proposals over high-risk, innovative ideas. The Next Generation of Biomedical and Behavioral Sciences Researchers: Breaking Through evaluates the factors that influence transitions into independent research careers in the biomedical and behavioral sciences and offers recommendations to improve those transitions. These recommendations chart a path to a biomedical research enterprise that is competitive, rigorous, fair, dynamic, and can attract the best minds from across the country.

Metabolomics for Biomedical Research

Metabolomics for Biomedical Research Book
Author : Jerzy Adamski, PhD
Publisher : Academic Press
Release : 2020-04-04
ISBN : 0128127848
Language : En, Es, Fr & De

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Book Description :

Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research. Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects. The book discusses topics such as biomarkers and their requirements to be used in medical research, with the parameters and approaches on how to validate their quality; and animal models and other approaches, as stem cells and organoid culture. Additionally, it explains how metabolomics may be applied in prediction of individual response to drug or disease progression. This book is a valuable source for researchers on systems biology and other members of biomedical field interested in metabolism-oriented studies for medical research. Focuses on metabolomics in translational and medical research Provides basics for, and concepts of, contemporary translational personalized medicine research with metabolomics Brings the major recent progresses on design, analytics, biostatistics and bioinformatics relating to the success of metabolomics research

Research in Medical and Biological Sciences

Research in Medical and Biological Sciences Book
Author : Petter Laake,Haakon Breien Benestad
Publisher : Academic Press
Release : 2015-06-05
ISBN : 0128001542
Language : En, Es, Fr & De

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Book Description :

Research in Medical and Biological Sciences covers the wide range of topics that a researcher must be familiar with in order to become a successful biomedical scientist. Perfect for aspiring as well as practicing professionals in the medical and biological sciences, this publication discusses a broad range of topics that are common yet not traditionally considered part of formal curricula, including philosophy of science, ethics, statistics, and grant applications. The information presented in this book also facilitates communication across conventional disciplinary boundaries, in line with the increasingly multidisciplinary nature of modern research projects. Covers the breadth of topics that a researcher must understand in order to be a successful experimental scientist Provides a broad scientific perspective that is perfect for students with various professional backgrounds Contains easily accessible, concise material about diverse methods Includes extensive online resources such as further reading suggestions, data files, statistical tables, and the StaTable application package Emphasizes the ethics and statistics of medical and biological sciences

Career Options for Biomedical Scientists

Career Options for Biomedical Scientists Book
Author : Kaaren A. Janssen,Richard Sever
Publisher : Unknown
Release : 2014-04-30
ISBN : 9781936113729
Language : En, Es, Fr & De

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Book Description :

Most people who do a PhD and postdoctoral work in the biomedical sciences do not end up as principal investigators in a research lab. Despite this, graduate courses and postdoctoral fellowships tend to focus almost exclusively on training for bench science rather than other career paths. This book plugs the gap by providing information about a wide variety of different careers that individuals with a PhD in the life sciences can pursue. Covering everything from science writing and grant administration to patent law and management consultancy, the book includes firsthand accounts of what the jobs are like, the skills required, and advice on how to get a foot in the door. It will be a valuable resource for all life scientists considering their career options and laboratory heads who want to give career advice to their students and postdocs.

Trends in Biomedical Research

Trends in Biomedical Research Book
Author : Mieczyslaw Pokorski
Publisher : Springer Nature
Release : 2020-02-28
ISBN : 3030412199
Language : En, Es, Fr & De

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Book Description :

This book addresses hot issues in the research and management of difficult-to-treat medical disorders that are commonly encountered, but for which the underlying mechanisms are often unknown. These include the adverse effects of hemodialysis and its biocompatibility in chronic kidney insufficiency, particularly related to malnutrition and inflammation, or the vulnerability of cancer patients to bacterial meningitis, the infection that remains underdiagnosed due to limited expression of symptoms. The book also covers other key topics, such as the psychological care of lung cancer patients; difficulties in the diagnosis of diffuse axonal injury in traumatic brain injury – a disorder with a poor prognosis and high mortality rate; and the virological aspects of seasonal influenza epidemic outbreaks – a perennial modern scourge. Further, it addresses recent developments in targeted drug delivery from titanium implants and a novel integrated thermal approach to rehabilitation of neurodegeneration-related disabilities. Featuring the latest interdisciplinary trends in biomedicine, this book connects research, theory and practice to help alleviate suffering caused by a variety of diseases. It is a resource for medical professionals, including academics, practitioners and all allied healthcare workers.