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Regenerative Nephrology

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Regenerative Nephrology

Regenerative Nephrology Book
Author : Michael S. Goligorsky
Publisher : Academic Press
Release : 2021-06-12
ISBN : 0128233192
Language : En, Es, Fr & De

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Book Description :

Since the publication of the first edition of this book in 2010, an explosion of spectacular discoveries in the field of regeneration has compelled the current revisit of the field of Regenerative Nephrology. This second edition features subjects as diverse as age and gender influencing regenerative processes; mechanisms and pathways of premature cell senescence affecting kidney regeneration; the ways intrinsic regenerative processes can become subverted by noxious stressors eventuating in disease progression; novel mechanistic and engineering efforts to recreate functional kidney or its component parts; cell reprogramming and reconditioning as emerging tools of future regenerative efforts; and effects of various biologicals on kidney regeneration. These newer additions to the armamentarium of Regenerative Medicine and Nephrology have become an integral part of the second edition of the book. Cutting-edge investigations are summarized by the constellation of the most experienced contributing authors coming together from around the world under the umbrella of the second edition. A significant expansion of section on induced pluripotent cells and trajectories of their differentiation. This will be followed by mechanisms and modalities of cell reprogramming for therapeutic purposes A new section on tissue engineering of the kidney of interest to nephrologists and urologists An entire section dedicated to causes of regenerative failure with the emphasis on recent discoveries of senescent cells in kidney disease, pathologic effects of senescent cells, advents in senotherapies and rejuvenation therapies A vastly expanded section on pharmacotherapies promoting kidney regeneration, trials of engineered organs, manufacturing in regenerative medicine and smooth transition to the clinical trials, with an update on some ethical issues

Perspectives in Regenerative Medicine

Perspectives in Regenerative Medicine Book
Author : Ena Ray Banerjee
Publisher : Springer
Release : 2014-10-20
ISBN : 8132220536
Language : En, Es, Fr & De

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Book Description :

The information given in this book tries to capture the essence of the sheer dynamicity of the cell along with useful tips on how to address critical rate limiting steps in the process of exploration and investigation of its capacity to regenerate, rebuild and replenish from within. The definitions of stem cells, stemness, and the niche concept continue to undergo revisions. In adult vertebrates, hematopoietic and some non-hematopoietic progenitors are synthesized within specialized niches of bone marrow. They migrate to designated tissues, and are either trans-differentiated or become quiescent and settle down. These form the stem cell niche reservoir in all tissues. Not only the primary hematopoietic tissue but all organs and tissues are also capable of generating progenitors which are either synthesized from these migrants or are direct recruits from other tissues. In the niches, the cells settle down and await their turn to either make more clones like themselves or differentiate and mobilize in an exigency. Thus progenitors are important reserves, to be multiplied and deployed or travel as important message bearing molecules via blood as circulating progenitors which can home to their allocated destinations. Upon reaching, specific integrins and selectins help them “dock” and “port” and they may be reprogrammed to induce further differentiation and help repopulate the denuded tissue. In pulmonary fibrosis and asthma, progenitors from both systemic circulation and local stem cell niches have been found to participate in the myriad ramifications of repair, replacement and regeneration of lost or diseased tissue. Whether they are lung specific or global in origin and role remain to be explored. Research tools, fundamental concepts, techniques, methodologies and standard operating protocols and animal models and human extrapolations, have been discussed in a concise way along with detailed description and discussion on the appropriate rationale to introduce the subject to the casual reader and provide valuable tactical information to the specialist in Regenerative Medicine. I sincerely hope you enjoy the work and appreciate the hard work that has gone into designing and executing elegant experiments by many researchers in the field. The branch is multi-disciplinary and I hope that the readers will not be limited to biologists alone.

Kidney Development Disease Repair and Regeneration

Kidney Development  Disease  Repair and Regeneration Book
Author : Melissa Helen Little
Publisher : Academic Press
Release : 2015-08-06
ISBN : 012800438X
Language : En, Es, Fr & De

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Book Description :

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology. Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally Explains the underlying developmental mechanisms which influence the kidney’s inherent repair capacity Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine

Kidney Transplantation Bioengineering and Regeneration

Kidney Transplantation  Bioengineering  and Regeneration Book
Author : Giuseppe Orlando,Giuseppe Remuzzi,David F. Williams
Publisher : Academic Press
Release : 2017-06-08
ISBN : 0128018364
Language : En, Es, Fr & De

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Book Description :

Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney. Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function

Exploring the State of the Science in the Field of Regenerative Medicine

Exploring the State of the Science in the Field of Regenerative Medicine Book
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Regenerative Medicine
Publisher : National Academies Press
Release : 2017-07-16
ISBN : 0309455081
Language : En, Es, Fr & De

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Book Description :

Regenerative medicine holds the potential to create living, functional cells and tissues that can be used to repair or replace those that have suffered potentially irreparable damage due to disease, age, traumatic injury, or genetic and congenital defects. The field of regenerative medicine is broad and includes research and development components of gene and cell therapies, tissue engineering, and non-biologic constructs. Although regenerative medicine has the potential to improve health and deliver economic benefits, this relatively new field faces challenges to developing policies and procedures to support the development of novel therapies are both safe and effective. In October 2016, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop with the goal of developing a broad understanding of the opportunities and challenges associated with regenerative medicine cellular therapies and related technologies. Participants explored the state of the science of cell-based regenerative therapies within the larger context of patient care and policy. This publication summarizes the presentations and discussions from the workshop.

Stem Cell Biology and Regenerative Medicine

Stem Cell Biology and Regenerative Medicine Book
Author : Mehdi Razavi
Publisher : Bentham Science Publishers
Release : 2017-10-02
ISBN : 168108578X
Language : En, Es, Fr & De

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Book Description :

Tissue engineering is an interdisciplinary field which involves the fabrication of tissues by using a porous protein scaffold, cells and bioactive molecules. The aim of tissue engineering is to enhance medical applications and procedures. This volume introduces the reader to the basics of employing pluripotent stem cells in tissue engineering. Successive chapters present knowledge about relevant tissue engineering techniques in different medical and physiological specialties including dentistry, cardiovascular physiology, hepatology, nephrology, dermatology and orthopedics. The text offers a wealth of information that will be of use to all students, bioengineers, materials scientists, chemists, physicians and surgeons concerned with the properties, performance, and the application of tissue engineering scaffolds in clinical settings.

Comprehensive Nephrology Nursing

Comprehensive Nephrology Nursing Book
Author : Cleo J. Richard
Publisher : Unknown
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Comprehensive Nephrology Nursing book written by Cleo J. Richard, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Organ Repair and Regeneration

Organ Repair and Regeneration Book
Author : Giuseppe Orlando,Shaf Keshavjee
Publisher : Academic Press
Release : 2021-01-14
ISBN : 0128194529
Language : En, Es, Fr & De

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Book Description :

Organ Repair and Regeneration: Preserving Organs in the Regenerative Medicine Era encompasses updates on all organs, from the kidneys, to the lungs, liver, pancreas, intestines, and beyond. Chapters cover the pathophysiology of ischemia-reperfusion, repairing organs with MSC, repairing cardiac allografts in situ, and much more. The book conceptualizes the idea that the modern approach to organ preservation is ante literam, a form of organ repair and regeneration which, per se, is referred to as a field of health sciences under the umbrella of regenerative medicine. This book demonstrates the merging of regenerative medicine and organ transplantation. Covers all aspects of organ preservation, repair and regeneration Addresses the repair of organs that experience an Ischemia/Reperfusion (I/R) injury, those that are intended for transplantation, and specific issues related to each organ Presented by editors and authors who are physicians, surgeons and researchers in the field of organ transplantation and regenerative medicine

Textbook of Nephrology

Textbook of Nephrology Book
Author : Shaul G. Massry,Richard J. Glassock
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Textbook of Nephrology book written by Shaul G. Massry,Richard J. Glassock, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Kidney Development Disease Repair and Regeneration

Kidney Development  Disease  Repair and Regeneration Book
Author : Melissa H. Little
Publisher : Academic Press
Release : 2015-09-03
ISBN : 9780128001028
Language : En, Es, Fr & De

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Book Description :

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology. Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally Explains the underlying developmental mechanisms which influence the kidney's inherent repair capacity Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine

International Urology and Nephrology

International Urology and Nephrology Book
Author : Anonim
Publisher : Unknown
Release : 1987
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download International Urology and Nephrology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Acute Kidney Injury and Regenerative Medicine

Acute Kidney Injury and Regenerative Medicine Book
Author : Yoshio Terada,Takashi Wada,Kent Doi
Publisher : Springer
Release : 2020-05-15
ISBN : 9789811511073
Language : En, Es, Fr & De

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Book Description :

This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis.Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.

Clinical Nephrology

Clinical Nephrology Book
Author : Anonim
Publisher : Unknown
Release : 2009-07
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Clinical Nephrology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Harrison s Nephrology and Acid Base Disorders

Harrison s Nephrology and Acid Base Disorders Book
Author : J. Larry Jameson,Joseph Loscalzo
Publisher : McGraw Hill Professional
Release : 2010-06-04
ISBN : 9780071663403
Language : En, Es, Fr & De

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Book Description :

Market: internal medicine clinicians (75,000), internal medicine residents (23,000), second and third year medical students (18,000/year), family practice residents and clinicians (55,000), nephrologists and fellows (5,000)

Harrison s Nephrology and Acid Base Disorders 2e

Harrison s Nephrology and Acid Base Disorders  2e Book
Author : J. Larry Jameson,Joseph Loscalzo
Publisher : McGraw Hill Professional
Release : 2013-03-22
ISBN : 0071814973
Language : En, Es, Fr & De

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Book Description :

Nephrology and Acid-Base Disorders – as only Harrison’s can cover it Featuring a superb compilation of chapters related to kidney function that appear in Harrison’s Principles of Internal Medicine, Eighteenth Edition, this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find content from renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation. Features Sections that reflect the scope of nephrology: Introduction to the Renal System; Alterations of Renal Function and Electrolytes; Acute Kidney Injury and Chronic Renal Failure; Glomerular and Tubular Disorders; Renal Vascular Disease; Urinary Tract Infections and Obstruction; and Cancer of the Kidney and Urinary Tract Complete coverage of a broad spectrum of topics, including acid-base and electrolyte disorders, vascular injury to the kidney, and specific diseases of the kidney Integration of pathophysiology with clinical management 41 high-yield questions and answers drawn from Harrison’s Principles of Internal Medicine Self-Assessment and Board Review, 18e Content updates and new developments since the publication of Harrison’s Principles of Internal Medicine, 18e 22 chapters written by physicians who are recognized experts in the field of nephrology and acid-base disorders Helpful appendix of laboratory values of clinical importance

Tissue Engineering for Artificial Organs

Tissue Engineering for Artificial Organs Book
Author : Anwarul Hasan
Publisher : John Wiley & Sons
Release : 2017-03-28
ISBN : 352768994X
Language : En, Es, Fr & De

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Book Description :

A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.

American Journal of Physiology

American Journal of Physiology Book
Author : Anonim
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Volumes for 1898-1941, 1948-56 include the Society's proceedings (primarily abstracts of papers presented at the 10th-53rd annual meetings, and the 1948-56 fall meetings).

Tissue Repair and Regeneration

Tissue Repair and Regeneration Book
Author : Leonard Eleazar Glynn
Publisher : Elsevier-North-Holland Biomedical Press
Release : 1981
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Tissue Repair and Regeneration book written by Leonard Eleazar Glynn, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Principles of Regenerative Medicine

Principles of Regenerative Medicine Book
Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publisher : Academic Press
Release : 2010-12-16
ISBN : 9780123814234
Language : En, Es, Fr & De

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Book Description :

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Seminars in Nephrology

Seminars in Nephrology Book
Author : Anonim
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Seminars in Nephrology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.