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Regenerative Engineering Of Musculoskeletal Tissues And Interfaces

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Regenerative Engineering of Musculoskeletal Tissues and Interfaces

Regenerative Engineering of Musculoskeletal Tissues and Interfaces Book
Author : Syam Nukavarapu,Joseph Freeman,Cato Laurencin
Publisher : Woodhead Publishing
Release : 2015-04-24
ISBN : 1782423141
Language : En, Es, Fr & De

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Book Description :

Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces. Comprehensive review of the repair and regeneration of musculoskeletal individual tissues and tissue interfaces Presents recent developments, fundamentals and progress in the field of engineering tissues Reviews progress and advances in tissue vascularization and innervation

Regenerative Engineering

Regenerative Engineering Book
Author : Cato T. Laurencin,Yusuf Khan
Publisher : CRC Press
Release : 2013-06-20
ISBN : 1482216833
Language : En, Es, Fr & De

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Book Description :

Distinct from tissue engineering, which focuses primarily on the repair of tissues, regenerative engineering focuses on the regeneration of tissues: creating living, functional tissue that has the ability to replace organs that are dysfunctional. The challenge of working in an area like regenerative engineering lies, in part, in the breadth of information required to truly appreciate and begin to think about this field. Regenerative Engineering introduces the field through the presentation of fundamental concepts of cell biology, stem cell science, materials science, and cell-material interactions. It also focuses on specific organ and tissue types and presents up-to-date examples of ongoing work, often in the context of a specific clinical need. Regenerative medicine focuses on the biological aspects of tissue regeneration via stem cells, factors, and cytokines, while tissue engineering focuses on the integration of materials science and life sciences. This book integrates these two areas, presenting each concept in the framework of regenerative engineering. Features: Covers a number of cutting-edge topics related to regenerative medicine and tissue engineering Includes an introductory chapter on materials science Features a number of the contributors who are world-class researchers, one of whom is Dr. Anthony Atala, whose work dealing with organ regenerative engineering was featured on Sixty Minutes Incorporates problem-based learning throughout the text, which is not hypothetical but based on actual biological, engineering, or clinical scenarios Combining science, engineering and medicine, Regenerative Engineering incorporates all of the essential elements needed for further advancement in this field. The book explores the development and examination of vital organs and tissue types and addresses concerns as it relates to the regenerative engineering of various organ tissues, vascular tissues, bone, ligament, neural tissue, and the interfaces between tissues.

Bio Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine

Bio Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine Book
Author : Justin Brown,Sangamesh Kumbar,Brittany Banik
Publisher : Academic Press
Release : 2016-11-03
ISBN : 0128033991
Language : En, Es, Fr & De

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Book Description :

Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics. Presents a self-contained work for the field of musculoskeletal tissue engineering and regenerative medicine Focuses on how materials of structures can be designed to be resistant while promoting viable grafts Contains major tissue types that are covered with a strategy for each material and structure

Nanoengineering in Musculoskeletal Regeneration

Nanoengineering in Musculoskeletal Regeneration Book
Author : Mehdi Razavi
Publisher : Academic Press
Release : 2020-08
ISBN : 0128202629
Language : En, Es, Fr & De

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Book Description :

Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation. Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of therapeutic pipeline from biomedical discovery to clinical implementation, improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus and bone. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in the musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues.

Racing for the Surface

Racing for the Surface Book
Author : Bingyun Li,Thomas Fintan Moriarty,Thomas Webster,Malcolm Xing
Publisher : Springer Nature
Release : 2020-02-28
ISBN : 3030344711
Language : En, Es, Fr & De

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Book Description :

This book covers the key basics of tissue engineering as well as the latest advances in the integration of both antimicrobial and osteoinductive properties. Topics covered include osteoconductive and osteoinductive biomaterials (calcium phosphate, bone morphogenetic protein, peptides, antibodies, bioactive glasses, nanomaterials, etc.) and scaffolds. Research integrating both antimicrobial/biofilm-inhibiting and osteoinductive/osteoconductive properties and their co-delivery is detailed and their roles in clinical success are discussed. Combined with its companion volume, Racing for the Surface: Antimicrobial and Interface Tissue Engineering, this book bridges the gap between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in tissue engineering and regeneration, infection, and biomaterials and devices.

Nanocomposites for Musculoskeletal Tissue Regeneration

Nanocomposites for Musculoskeletal Tissue Regeneration Book
Author : Huinan Liu
Publisher : Woodhead Publishing
Release : 2016-03-01
ISBN : 9781782424529
Language : En, Es, Fr & De

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Book Description :

Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced biomaterials scientists are exploring for use as tools to mimic the structure of musculoskeletal tissues. Bone and other musculoskeletal tissues naturally have a nanocomposite structure, therefore nanocomposites are ideally suited as a material for replacing and regenerating these natural tissues. In addition, biological properties such as biointegration and the ability to tailor and dope the materials make them highly desirable for musculoskeletal tissue regeneration. Provides a comprehensive discussion on the design and advancements made in the use of nanocomposites for musculoskeletal tissue regeneration Presents an In-depth coverage of material properties Includes discussions on polymers, ceramics, and glass

Nanotechnology and Regenerative Engineering

Nanotechnology and Regenerative Engineering Book
Author : Cato T. Laurencin,Lakshmi S. Nair
Publisher : CRC Press
Release : 2014-10-28
ISBN : 1466585382
Language : En, Es, Fr & De

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Book Description :

Nanotechnology and regenerative engineering have emerged to the forefront as the most versatile and innovative technologies to foster novel therapeutic techniques and strategies of the twenty-first century. The first edition of Nanotechnology and Tissue Engineering: The Scaffold was the first comprehensive source to explain the developments in nanostructured biomaterials for tissue engineering, the relevance of nanostructured materials in tissue regeneration, and the current applications of nanostructured scaffolds for engineering various tissues. This fully revised second edition, renamed Nanotechnology and Regenerative Engineering: The Scaffold, provides a thorough update to the existing material, bringing together these two unique areas to give a perspective of the emerging therapeutic strategies for a wide audience. New coverage includes: Updated discussion of the importance of scaffolds in tissue engineering Exploration of cellular interactions at the nanoscale Complete range of fabrication processes capable of developing nanostructured scaffolds for regenerative engineering Applications of nanostructured scaffolds for neural, skin, cardiovascular, and musculoskeletal regenerative engineering FDA approval process of nanostructure scaffolds Products based on nanostructured scaffolds Due to the unique and tissue-mimic properties of the nanostructured scaffolds, the past five years have seen a tremendous growth in nanostructured materials for biological applications. The revised work presents the current state-of-the-art developments in nanostructured scaffolds for regenerative engineering.

3D Bioprinting in Regenerative Engineering

3D Bioprinting in Regenerative Engineering Book
Author : Ali Khademhosseini,Gulden Camci-Unal
Publisher : CRC Press
Release : 2018-04-17
ISBN : 1315280477
Language : En, Es, Fr & De

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Book Description :

This book is comprehensive in nature with contributions by leading world experts in 3D bioprinting related to regenerative engineering. It includes history, incorporating the process and methods used in bioprinting. Significant sections will be reserved for the applications of the types of tissues generated by using bioprinting, along with an overview of different technologies used in bioprinting. In addition to equipment, the book also describes the different biomaterials and cells used in these approaches. Overall this is a book that includes both entry-level knowledge and advanced methods and techniques. Applications will emphasize engineering and clinical principles.

Surfaces and Interfaces for Biomaterials

Surfaces and Interfaces for Biomaterials Book
Author : Pankaj Vadgama
Publisher : Elsevier
Release : 2005-05-27
ISBN : 184569080X
Language : En, Es, Fr & De

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Book Description :

Given such problems as rejection, the interface between an implant and its human host is a critical area in biomaterials. Surfaces and interfaces for biomaterials summarises the wealth of research on understanding the surface properties of biomaterials and the way they interact with human tissue. The first part of the book reviews the way biomaterial surfaces form. Part Two discusses ways of monitoring and characterising surface structure and behaviour. The final two parts of the book look at a range of in vitro and in vivo studies of the complex interactions between biomaterials and the body. Chapters cover such topics as bone and tissue regeneration, the role of interface interactions in biodegradable biomaterials, microbial biofilm formation, vascular tissue engineering and ways of modifying biomaterial surfaces to improve biocompatibility. Surfaces and interfaces for biomaterials is a standard work on how to understand and control surface processes in ensuring biomaterials are used successfully in medicine. Complete coverage on the fundamentals of surface structure and forming to biological and clinical outcomes Includes reviews of key surface analytical techniques Edited by a renowned expert and written by an international team of authors

Micro and Nanotechnologies in Engineering Stem Cells and Tissues

Micro and Nanotechnologies in Engineering Stem Cells and Tissues Book
Author : Murugan Ramalingam,Esmaiel Jabbari,Seeram Ramakrishna,Ali Khademhosseini
Publisher : John Wiley & Sons
Release : 2013-05-10
ISBN : 111857480X
Language : En, Es, Fr & De

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Book Description :

A cutting-edge look at the application of micro andnanotechnologies in regenerative medicine The area at the interface of micro/nanotechnology and stemcells/tissue engineering has seen an explosion of activity inrecent years. This book provides a much-needed overview of theseexciting developments, covering all aspects of micro andnanotechnologies, from the fundamental principles to the latestresearch to applications in regenerative medicine. Written and edited by the top researchers in the field, Microand Nanotechnologies in Engineering Stem Cells and Tissuesdescribes advances in material systems along with currenttechniques available for cell, tissue, and organ studies. Readerswill gain tremendous insight into the state of the art of stemcells and tissue engineering, and learn how to use the technologyin their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissuegrowth Various engineering approaches for stem cell, vascular tissue,and bone regeneration The design and processing of biocompatible polymers and otherbiomaterials Characterization of the interactions between cells andbiomaterials Unrivaled among books of this kind, Micro andNanotechnologies in Engineering Stem Cells and Tissues is theultimate forward-looking reference for researchers in numerousdisciplines, from engineering and materials science to biomedicine,and for anyone wishing to understand the trends in thistransformative field.

Osteochondral Tissue Engineering

Osteochondral Tissue Engineering Book
Author : J. Miguel Oliveira,Sandra Pina,Rui L. Reis,Julio San Roman
Publisher : Springer
Release : 2018-04-24
ISBN : 3319767119
Language : En, Es, Fr & De

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Book Description :

This book reviews the most recent developments in the field of osteochondral tissue engineering (OCTE) and presents challenges and strategies being developed that face not only bone and cartilage regeneration, but also establish osteochondral interface formation in order to translate it into a clinical setting. Topics include nanotechnology approaches and biomaterials advances in osteochondral engineering, advanced processing methodology, as well as scaffolding and surface engineering strategies in OCTE. Hydrogel systems for osteochondral applications are also detailed thoroughly. Osteochondral Tissue Engineering: Nanotechnology, Scaffolding-Related Developments and Translation is an ideal book for biomedical engineering students and a wide range of established researchers and professionals working in the orthopedic field.

Polymers for Regenerative Medicine

Polymers for Regenerative Medicine Book
Author : Carsten Werner
Publisher : Springer Verlag
Release : 2006-07-20
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Table of contents - T. Freier - Biopolyesters in Tissue Engineering Applications.- C. Werner, T. Pompe, K. Salchert - Modulating Extracellular Matrix at Interfaces of Polymeric Materials.- S. Varghese, J.H. Elisseeff - Hydrogels for Musculoskeletal Tissue Engineering.- X. Zhao, S. Zhang - Self-Assembling Nanopeptides Become a New Type of Biomaterials.- A.J. Garcia - Interfaces to Control Cell-Biomaterial Adhesive Interactions.- C. Fischbach, D.J. Mooney - Polymeric Systems for Bioinspired Delivery of Angiogenic Molecules.

Biomaterials Science

Biomaterials Science Book
Author : William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski
Publisher : Academic Press
Release : 2020-05-23
ISBN : 0128161388
Language : En, Es, Fr & De

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Book Description :

The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for each chapter

Functional Tissue Engineering

Functional Tissue Engineering Book
Author : Farshid Guilak,David L. Butler,Steven A. Goldstein,David Mooney
Publisher : Springer Science & Business Media
Release : 2006-04-20
ISBN : 0387215476
Language : En, Es, Fr & De

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Book Description :

-Softcover reprint of a successful hardcover reference (370 copies sold) -Price to be accessible to the rapidly increasing population of students and investigators in the field of tissue engineering -Chapters written by well-known researchers discuss issues in functional tissue engineering as well as provide guidelines and a summary of the current state of technology

Cells and Biomaterials in Regenerative Medicine

Cells and Biomaterials in Regenerative Medicine Book
Author : Daniel Eberli
Publisher : BoD – Books on Demand
Release : 2014-11-26
ISBN : 9535117319
Language : En, Es, Fr & De

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Book Description :

This book serves as a good starting point for anyone interested in the application of tissue engineering. It offers a colorful mix of topics, which explain the obstacles and possible solutions for TE applications. The first part covers the use of adult stem cells and their applications. The following chapters offer an insight into the development of a tailored biomaterial for organ replacement and highlight the importance of cell-biomaterial interaction. In summary, this book offers insights into a wide variety of cells, biomaterials, interfaces and applications of the next generation biotechnology, which is tissue engineering.

Nanostructures for the Engineering of Cells Tissues and Organs

Nanostructures for the Engineering of Cells  Tissues and Organs Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2018-02-14
ISBN : 0128136669
Language : En, Es, Fr & De

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Book Description :

Nanostructures for the Engineering of Cells: Tissues and Organs showcases recent advances in pharmaceutical nanotechnology, with particular emphasis on tissue engineering, organ and cell applications. The book provides an up-to-date overview of organ targeting and cell targeting using nanotechnology. In addition, tissue engineering applications, such as skin regeneration are also discussed. Written by a diverse range of international academics, this book is a valuable research resource for researchers working in the biomaterials, medical and pharmaceutical industries. Explains how nanomaterials regulate different cell behavior and function as a carrier for different biomolecules Shows how nanobiomaterials and nanobiodevices are used in a range of treatment areas, such as skin tissue, wound healing and bone regeneration Discusses nanomaterial preparation strategies for pharmaceutical application and regenerative medicine

Journal of the Royal Society Interface

Journal of the Royal Society Interface Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Journal of the Royal Society Interface book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

An Introduction to Biomaterials Second Edition

An Introduction to Biomaterials  Second Edition Book
Author : Jeffrey O. Hollinger
Publisher : CRC Press
Release : 2011-11-28
ISBN : 1439812578
Language : En, Es, Fr & De

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Book Description :

A practical road map to the key families of biomaterials and their potential applications in clinical therapeutics, Introduction to Biomaterials, Second Edition follows the entire path of development from theory to lab to practical application. It highlights new biocompatibility issues, metrics, and statistics as well as new legislation for intellectual property. Divided into four sections (Biology, Biomechanics, Biomaterials Interactions; Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property; Biomaterials Compositions; and Biomaterials Applications), this dramatically revised edition includes both new and revised chapters on cells, tissues, and signaling molecules in wound healing cascades, as well as two revised chapters on standardized materials testing with in vitro and in vivo paradigms consistent with regulatory guidelines. Emphasizing biocompatibility at the biomaterial-host interface, it investigates cell-cell interactions, cell-signaling and the inflammatory and complement cascades, specific interactions of protein-adsorbed materials, and other inherent biological constraints including solid-liquid interfaces, diffusion, and protein types. Unique in its inclusion of the practicalities of biomaterials as an industry, the book also covers the basic principles of statistics, new U.S. FDA information on the biomaterials-biology issues relevant to patent applications, and considerations of intellectual property and patent disclosure. With nine completely new chapters and 24 chapters extensively updated and revised with new accomplishments and contemporary data, this comprehensive introduction discusses 13 important classes of biomaterials, their fundamental and applied research, practical applications, performance properties, synthesis and testing, potential future applications, and commonly matched clinical applications. The authors include extensive references, to create a comprehensive, yet manageable didactic work that is an invaluable desk references and instructional text for undergraduates and working professionals alike.

Tissue Engineering in Musculoskeletal Clinical Practice

Tissue Engineering in Musculoskeletal Clinical Practice Book
Author : Linda Jo Sandell,Alan J. Grodzinsky
Publisher : Amer Academy of Orthopaedic
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Gain new insight into the potential for tissue engineering as a biological solution to the critical need for human tissues. A compilation of proceedings from the "Tissue Engineering in Musculoskeletal Clinical Practice" workshop held in Santa Fe, NM, in January 2003.