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Recent Advances In Medicinal Chemistry

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Recent Advances in Medicinal Chemistry

Recent Advances in Medicinal Chemistry Book
Author : Atta-ur-Rahman,Muhammad Iqbal Choudhary,George Perry
Publisher : Elsevier
Release : 2015-06-16
ISBN : 0128039620
Language : En, Es, Fr & De

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Book Description :

Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more. Edited and written by leading experts in medicinal chemistry research Reviews recent advances in the field, including the characterization of inorganic nanomaterials as therapeutic vehicles Covers a variety of topical areas, such as HPLC and in the analysis of tricyclic antidepressants in biological samples, and tannins and their influence on health

Recent Advances in Medicinal Chemistry

Recent Advances in Medicinal Chemistry Book
Author : Anonim
Publisher : Unknown
Release : 1974
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Recent Advances in Medicinal Chemistry book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Recent Advances in Medicinal Chemistry

Recent Advances in Medicinal Chemistry Book
Author : Mark Bamford (Fellow of the association for the advancement of science)
Publisher : Unknown
Release : 2013
ISBN : 9789382220459
Language : En, Es, Fr & De

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Book Description :

Download Recent Advances in Medicinal Chemistry book written by Mark Bamford (Fellow of the association for the advancement of science), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Recent Advances in Bioorganic and Medicinal Chemistry

Recent Advances in Bioorganic and Medicinal Chemistry Book
Author : Dale L. Boger
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Recent Advances in Bioorganic and Medicinal Chemistry book written by Dale L. Boger, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Recent Advances in Phytochemistry

Recent Advances in Phytochemistry Book
Author : V. Runeckles
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1468408232
Language : En, Es, Fr & De

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Book Description :

For centuries it has been recognized that plants relate to human health and well-being in many ways beyond their fundamental role as primary sources of food and energy. Many of the unique plant constituents have pronounced effects on animal systems or in the human body; some of them are potentially harmful and represent a risk in the use of a parttcular plant or in the exposure to it, others are useful as medicinal agents in the treatment of diseases. Many of the latter are extracted from plant materials on a large scale for marketing as drugs and even more of them have served as structural prototypes which inspired chemists to synthesize analog drugs with even more desirable properties. Clearly, today's drug therapy had its origins in the explora tion and exploitation of pharmacologically active plant con stituents. It is therefore appropriate that a symposium of the Phytochemical Society of tlorth America \'1as devoted to this subject. The present volume consists of eleven rapers dealing with various aspects of the topic "Phytochemistry as Related to Disease and Medicine", which were presented at the Four teenth Annual Meeting of the Phytochemical Society of tlorth America held tn August 1974 at Hestern Carol ina University in Cullowhee, N.C. Plant hallucinogens are the subject of the first three chapters. The first, by Schultes, reviews the occurrence of hallucinogenic agents in plants, in tabular form. Emphasis is on plants from Central and South America.

Advances in Medicinal Chemistry Research

Advances in Medicinal Chemistry Research Book
Author : Edeildo Ferreira Da Silva, Jr.
Publisher : Unknown
Release : 2019-10-15
ISBN : 9781536163681
Language : En, Es, Fr & De

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Book Description :

Advances in Medicinal Chemistry Research is a book addressed to undergraduate and postgraduate students, where recent advances in the discovery and development of effective agents against the most remarkable wide-reaching diseases are presented, divided into seven chapters. This first edition of Advances in Medicinal Chemistry Research offers insights into medicinal chemistry that arguably have the most significant impact on our lives than any other. It draws together research on therapeutic agents from natural, synthetic, and virtual screening sources as starting points for the design of drugs against obesity, multidrug-resistant bacteria, neglected tropical diseases, Alzheimer, and cancer. From the prediction of promising hits and identification of active compounds to the extraction of more complex molecules, this book explores a range of essential topics to support the development of novel, economical, and efficacious therapeutics for these diseases, which currently affect a billion people worldwide. Beginning with an overview of obesity, showing the current research landscape, the books shows the importance of natural and synthetic products as promising anti-obesity agents. Subsequently, the medicinal chemistry of modulation of bacterial resistance is presented, focusing on the MFS, RND, ABC, and MATE superfamilies. The book goes on to discuss such topics as antituberculosis, antileishmanial, and anti-hepatitis thiophene-containing compounds, under the medicinal chemistry point of view. Also, potent human glutaminyl cyclase inhibitors are deeply discussed and displayed as hopeful anti-Alzheimer's agents. The last three chapters are focused on the development of researches involving new anticancer agents, initializing with LBDD, SBDD, QSAR, and QM/MM methods applied to the identification of novel promising anticancer compounds. Moreover, IDO1 inhibitors are exhaustively explored and analyzed as a new promise for the immunotherapy of cancer. Finally, a great update on Eg5 kinesin inhibitors is provided, exploring different chemical classes of synthetic and natural compounds, including miscellanea as a new approach for Eg5 inhibition. Combining the expertise of researchers from around the world, this volume aims to support and encourage researches for the development of novel, safe, and active agents against lipase enzyme, bacteria, neglected tropical diseases, Alzheimer, and cancer. The clear narrative truly engages the reader, holding their attention right from the opening of a chapter, and maintaining interest and understanding as a chapter leads into more complex material. Advances in Medicinal Chemistry Research is a book that reviews ongoing developments and recent cutting-edge advances in medicinal chemistry of the most relevant diseases found nowadays, underlining how medicinal chemistry research continues to make significant contributions to the discovery and development of new therapeutic entities. Key Features â¢Chapters written by active specialists and leading experts deeply engaged in the research field of most deadly and limiting diseases for drug discovery. â¢Draws together cutting-edge research advances in medicinal chemistry focused at the obesity, multidrug-resistant microorganisms, Alzheimer, and cancer in a single volume. â¢Highlights the future potential of researches for the medicinal chemistry of most impactful diseases today. â¢Contents addressed to medicinal chemistry, biochemistry, biology, and pharmacy students, professors, and researchers.

Advances in Medicinal Chemistry

Advances in Medicinal Chemistry Book
Author : Bruce E. Maryanoff
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Advances in Medicinal Chemistry book written by Bruce E. Maryanoff, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry Book
Author : Camille Georges Wermuth,David Aldous,Pierre Raboisson,Didier Rognan
Publisher : Elsevier
Release : 2015-07-01
ISBN : 012417213X
Language : En, Es, Fr & De

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Book Description :

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research An image bank is available for instructors at www.textbooks.elsevier.com

Progress in Medicinal Chemistry

Progress in Medicinal Chemistry Book
Author : F... D... King,A. W. Oxford
Publisher : Elsevier Science Limited
Release : 2000-01-01
ISBN : 9780444502940
Language : En, Es, Fr & De

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Book Description :

Hardbound. This volume reviews recent advances in five important areas of medicinal chemistry which will be of interest both to chemists and to scientists of other disciplines engaged in medicines research and development. Included are accounts of successful drug discovery programmes, disease targets of unmet medical need, and recent progress in new technologies which are considered by many to hold the key to future developments in medicinal chemistry.The style and organisation of chapters follow a similar pattern to previous volumes but references, where appropriate, now include website addresses of the World Wide Web.

Handbook of Research on Medicinal Chemistry

Handbook of Research on Medicinal Chemistry Book
Author : Debarshi Kar Mahapatra,Sanjay Kumar Bharti
Publisher : Taylor & Francis
Release : 2017-11-20
ISBN : 1771885459
Language : En, Es, Fr & De

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Book Description :

This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and nutraceuticals. The editors keep the drug molecule as the central component of the volume and aim to explain the associated features essential to exhibiting pharmacological activity. With a unique combination of chapters in biology, clinical aspects, biochemistry, synthetic chemistry, medicine and technology, the volume provides broad exposure to the essential aspect of pharmaceuticals. The volume many important aspects of medicinal chemistry, including techniques in drug discovery pharmacological aspects of natural products chemical mediators: druggable targets advances in medicinal chemistry The field of medicinal chemistry is growing at an unprecedented pace, and this volume takes an interdisciplinary approach, covering a range of new research and new practices in the field. The volume takes into account the latest therapeutic guidelines put forward by the World Health Organization and the U.S Food and Drug Administration.. Topics include: drug design drug discovery natural products and supplements and nutraceuticals pharmaceutical approaches to sexual dysfunction drug resistance parasites new natural compounds and identification of new targets stereochemistry aspects in medicinal chemistry common drug interactions in daily practices Handbook of Research on Medicinal Chemistry: Innovations and Methodologies will be a valuable addition to the bookshelves of pharmaceutical scientists and faculty as well as for industry professionals.

Recent Advances in Medicinal Chemistry

Recent Advances in Medicinal Chemistry Book
Author : Atta-ur-Rahman,Muhammad Iqbal Choudhary,George Perry
Publisher : Bentham Science Publishers
Release : 2015-12-01
ISBN : 1681081717
Language : En, Es, Fr & De

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Book Description :

Recent Advances in Medicinal Chemistry is a book series focused on leading-edge research on developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The series presents highly cited contributions first published in the impact factor journal Mini-Reviews in Medicinal Chemistry. Contributors to this volume have updated their work with new experimental data and references following their initial research. Each volume highlights a number of important topics in current research in medicinal chemistry. Selected chapters in this volume include: - A brief review of polyphenols as phytotherapeutic agents - Flavonoids in foods and biological samples - Cannabinoid use in treating Parkinson’s Disease symptoms … And much more.

Recent advances in the chemistry of anti infective agents

Recent advances in the chemistry of anti infective agents Book
Author : Anonim
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Recent advances in the chemistry of anti infective agents book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Recent Advances in Vitamin D Chemistry and Pharmacological Activity

Recent Advances in Vitamin D Chemistry and Pharmacological Activity Book
Author : M. R. Uskokovic
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Recent Advances in Vitamin D Chemistry and Pharmacological Activity book written by M. R. Uskokovic, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Recent Advances in the DNA Binding Agents

Recent Advances in the DNA Binding Agents Book
Author : Robert S. Coleman
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Recent Advances in the DNA Binding Agents book written by Robert S. Coleman, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Recent Advances in Mechanism based Enzyme Inhibitors

Recent Advances in Mechanism based Enzyme Inhibitors Book
Author : Chi-Huey Wong
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Recent Advances in Mechanism based Enzyme Inhibitors book written by Chi-Huey Wong, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Medicinal Chemistry Third Edition

Medicinal Chemistry Third Edition Book
Author : Gerardus Blokdyk
Publisher : 5starcooks
Release : 2018-05-12
ISBN : 9780655192848
Language : En, Es, Fr & De

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Book Description :

At what point will vulnerability assessments be performed once Medicinal chemistry is put into production (e.g., ongoing Risk Management after implementation)? How does the Medicinal chemistry manager ensure against scope creep? Who will provide the final approval of Medicinal chemistry deliverables? To what extent does management recognize Medicinal chemistry as a tool to increase the results? What would happen if Medicinal chemistry weren't done? Defining, designing, creating, and implementing a process to solve a challenge or meet an objective is the most valuable role... In EVERY group, company, organization and department. Unless you are talking a one-time, single-use project, there should be a process. Whether that process is managed and implemented by humans, AI, or a combination of the two, it needs to be designed by someone with a complex enough perspective to ask the right questions. Someone capable of asking the right questions and step back and say, 'What are we really trying to accomplish here? And is there a different way to look at it?' This Self-Assessment empowers people to do just that - whether their title is entrepreneur, manager, consultant, (Vice-)President, CxO etc... - they are the people who rule the future. They are the person who asks the right questions to make Medicinal chemistry investments work better. This Medicinal chemistry All-Inclusive Self-Assessment enables You to be that person. All the tools you need to an in-depth Medicinal chemistry Self-Assessment. Featuring 700 new and updated case-based questions, organized into seven core areas of process design, this Self-Assessment will help you identify areas in which Medicinal chemistry improvements can be made. In using the questions you will be better able to: - diagnose Medicinal chemistry projects, initiatives, organizations, businesses and processes using accepted diagnostic standards and practices - implement evidence-based best practice strategies aligned with overall goals - integrate recent advances in Medicinal chemistry and process design strategies into practice according to best practice guidelines Using a Self-Assessment tool known as the Medicinal chemistry Scorecard, you will develop a clear picture of which Medicinal chemistry areas need attention. Your purchase includes access details to the Medicinal chemistry self-assessment dashboard download which gives you your dynamically prioritized projects-ready tool and shows your organization exactly what to do next. Your exclusive instant access details can be found in your book.

Fluorinated Pharmaceuticals

Fluorinated Pharmaceuticals Book
Author : Andrew D. Westwell
Publisher : Unknown
Release : 2015
ISBN : 9781909453968
Language : En, Es, Fr & De

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Book Description :

Download Fluorinated Pharmaceuticals book written by Andrew D. Westwell, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Advances in Medicinal Chemistry

Advances in Medicinal Chemistry Book
Author : A.B. Reitz,S.L. Dax
Publisher : Elsevier
Release : 1999-12-27
ISBN : 9780080526775
Language : En, Es, Fr & De

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Book Description :

Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.

Ion Channel Drug Discovery

Ion Channel Drug Discovery Book
Author : Brian Cox,Martin Gosling
Publisher : Royal Society of Chemistry
Release : 2014-09-03
ISBN : 1849735085
Language : En, Es, Fr & De

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Book Description :

Ion channel drug discovery is a rapidly evolving field fuelled by recent, but significant, advances in our understanding of ion channel function combined with enabling technologies such as automated electrophysiology. The resurgent interest in this target class by both pharmaceutical and academic scientists was clearly highlighted by the over-subscribed RSC/BPS 'Ion Channels as Therapeutic Targets' symposium in February 2009. This book builds on the platform created by that meeting, covering themes including advances in screening technology, ion channel structure and modelling and up-to-date case histories of the discovery of modulators of a range of channels, both voltage-gated and non-voltage-gated channels. The editors have built an extensive network of contacts in the field through their first-hand scientific experience, collaborations and conference participation and the organisation of the meeting at Novartis, Horsham, increased the network enabling the editors to draw on the experience of eminent researchers in the field. Interest and investment in ion channel modulation in both industrial and academic settings continues to grow as new therapeutic opportunities are identified and realised for ion channel modulation. This book provides a reference text by covering a combination of recent advances in the field, from technological and medicinal chemistry perspectives, as well as providing an introduction to the new 'ion channel drug discoverer'. The book has contributions from highly respected academic researchers, industrial researchers at the cutting edge of drug discovery and experts in enabling technology. This combination provides a complete picture of the field of interest to a wide range of readers.