Skip to main content

Rearrangements With Migration To Electrophilic Heteroatomic Centers

Download Rearrangements With Migration To Electrophilic Heteroatomic Centers Full eBooks in PDF, EPUB, and kindle. Rearrangements With Migration To Electrophilic Heteroatomic Centers is one my favorite book and give us some inspiration, very enjoy to read. you could read this book anywhere anytime directly from your device.

Rearrangements with Migration to Electrophilic Heteroatomic Centers

Rearrangements with Migration to Electrophilic Heteroatomic Centers Book
Author : Sosale Chandrasekhar
Publisher : Elsevier
Release : 2022-01-15
ISBN : 9780128237434
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Rearrangements with Migration to Electrophilic Heteroatomic Centers: Timeless Classics in Organic Synthesis covers the basic principles and synthetic applications of a critically important class of organic reactions that date back to the founding period of organic chemistry. These reactions are not only of historical and pedagogical interest, but also have great practical value to this day, being inevitable in any strategy concerning the introduction of nitrogen and oxygen functionality. The book is made up of three parts, dealing with the Beckmann reaction, the Hoffmann family of reactions and the Baeyer-Villiger reaction. Each part begins with a brief historical introduction followed by a mechanistic discussion. The synthetic applications are then discussed in detail, focusing on current developments and improvements. The book strikes a balance between delineation and exhaustiveness, with up-to-date refences for readers requiring in-depth coverage. Relevant industrial applications, including pharmaceutical processes, are included. This reference will be a key resource for organic synthesis researchers and students, working in academia and industry. Summarizes mechanistic background with an emphasis on synthetic applications Up to date references allow for locating original papers for experimental procedures Applications in the synthesis of complex molecules and natural products are included to judge the scope and limitations of each reaction

Modern Physical Organic Chemistry

Modern Physical Organic Chemistry Book
Author : Eric V. Anslyn,Dennis A. Dougherty
Publisher : University Science Books
Release : 2006
ISBN : 9781891389313
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

In additionto covering thoroughly the core areas of physical organic chemistry -structure and mechanism - this book will escort the practitioner of organic chemistry into a field that has been thoroughlyupdated.

Advances in Heterocyclic Chemistry

Advances in Heterocyclic Chemistry Book
Author : Anonim
Publisher : Elsevier
Release : 2000-07-04
ISBN : 0080493564
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

Organic Reactions Volume 102

Organic Reactions  Volume 102 Book
Author : Anonim
Publisher : John Wiley & Sons
Release : 2020-07-08
ISBN : 1119651220
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

The 102nd volume in this series for organic chemists in academia and industry presents critical discussions of widely used organic reactions or particular phases of a reaction. The material is treated from a preparative viewpoint, with emphasis on limitations, interfering influences, effects of structure and the selection of experimental techniques. The work includes tables that contain all possible examples of the reaction under consideration. Detailed procedures illustrate the significant modifications of each method.

Organic Syntheses Based on Name Reactions and Unnamed Reactions

Organic Syntheses Based on Name Reactions and Unnamed Reactions Book
Author : Alfred Hassner,C Stumer
Publisher : Elsevier
Release : 2013-10-22
ISBN : 1483287343
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find. In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form. In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions. Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Shazia Anjum,Elena Soriano,José Luis Marco-Contelles
Publisher : Elsevier Inc. Chapters
Release : 2013-06-25
ISBN : 0128084685
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Molecular rearrangements occupy center stage in the development of organic synthesis and, consequently, in the impressive achievements that have resulted in the total synthesis of many complex natural products in the last decades. The purpose of this chapter, in this volume of a book series dedicated to the Studies in Natural Product Chemistry, is to show a set of selected and organized molecular rearrangements based on a personal choice of expertise related to the synthesis of complex bioactive molecules. Our selection addresses [3,3]-sigmatropic rearrangements, which continue to provide excellent opportunities for reaching high chemical diversity, operating in efficient synthetic schemes. [3,3]-Sigmatropic rearrangements, such as the Cope and Claisen rearrangements, are among the most basic and useful transformations in synthetic organic chemistry. This is possibly due to the fact that these rearrangements are efficient methods for the synthesis of quaternary, sterically hindered chiral centers, and for the stereoselective formation of carbon–carbon and carbon–heteroatom bonds. In addition, [3,3]-sigmatropic rearrangements can be easily integrated in, and adapted to, cascade processes as a simple method to prepare complex molecules in atom-efficient reactions. Consequently, in the context of [3,3]-sigmatropic rearrangements, we focus on the transformations of propargylic esters, whose rearrangements, in different experimental conditions, have been largely exploited for the synthesis of interesting key and useful intermediates. The rearrangements can be promoted by protic acids, Lewis acids, and noble metals such as Pt, Au, or Cu salts, or complexes that have recently emerged as the most popular and potent electrophilic activators of alkynes toward a number of nucleophilic agents, under homogeneous conditions.

Silver Catalysis in Organic Synthesis 2 Volume Set

Silver Catalysis in Organic Synthesis  2 Volume Set Book
Author : Chao-Jun Li,Xihe Bi
Publisher : John Wiley & Sons
Release : 2019-04-29
ISBN : 3527342818
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Covers all the aspects of the recent achievements in silver catalyzed reactions Silver catalysis has emerged as a powerful tool in the field of organic synthesis. This comprehensive book systematically explores the unique performance of silver catalysis, introducing all the recent progress of silver catalysis in organic synthesis. It clearly emphasizes the unique features of silver catalysis and provides the reaction mechanism involved. This two-volume book also provides vivid schematics and tables throughout to enhance the accessibility to the relevant theory and mechanisms. Silver Catalysis in Organic Synthesis begins with an introduction to Silver Chemistry before moving on to chapters covering: Silver-Catalyzed Cycloaddition Reactions; Silver-Catalyzed Cyclizations; Silver-Mediated Radical Reactions; Silver-Mediated Fluorination, Perfluoroalkylation and Trifluoromethylthiolation Reactions; Coupling Reactions and C-H Functionalization; Silver-Catalyzed CO2 Incorporation; Silver-Catalyzed Carbene, Nitrene, and Silylene Transfer Reactions; Asymmetric Silver-Catalyzed Reactions; Silver-Catalyzed Reduction and Oxidation of Aldehydes and Their Derivatives; Silver Complexes in Organic Transformations; and Silver Nanoparticles in Organic Transformations. -Covers recently developed organic reactions catalyzed by silver, along with their reaction mechanism -Introduces many new reactions and mechanisms related to silver catalysis -Offers professionals and newcomers in the related fields a survey of new advances in silver catalysis in organic synthesis Silver Catalysis in Organic Synthesis will appeal to a wide readership including chemists, biochemists, pharmaceutical scientists, biomedical researchers, agriculture scientists, and graduate students in the related fields.

Strategic Applications of Named Reactions in Organic Synthesis

Strategic Applications of Named Reactions in Organic Synthesis Book
Author : Laszlo Kurti,Barbara Czako
Publisher : Elsevier
Release : 2005-04-29
ISBN : 0080575412
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding * 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples * An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools * Extensive index quickly locates information using words found in text and drawings

Applied Organic Chemistry

Applied Organic Chemistry Book
Author : Surya K. De
Publisher : John Wiley & Sons
Release : 2021-03-08
ISBN : 3527347852
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

An indispensable guide for all synthetic chemists who want to learn about the most relevant reactions and reagents employed to synthesize important heterocycles and drugs! The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin. Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry. Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry. Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin. Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area. User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions. Applied Organic Chemistry is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.

Advanced Organic Chemistry

Advanced Organic Chemistry Book
Author : Bernard Miller
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This text covers the principles of mechanisms of organic reactions in a qualitative way and features a chapter on heterocyclic chemistry. End of chapter exercises feature references to current literature

Vinyl Cations

Vinyl Cations Book
Author : Peter Stang
Publisher : Elsevier
Release : 2012-12-02
ISBN : 0323147089
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Vinyl Cations provides a comprehensive and detailed treatment of the reactive intermediate in which the electron-deficient carbon is an integral part of a ? unsaturation. This book emphasizes that the reaction through vinyl cations is a viable pathway among the multitude of mechanistic routes for vinylic substitution. The aryl, ethynyl, and allenyl cations from the viewpoint of direct solvolytic generation from appropriate allenyl precursors are briefly discussed. Other topics include the preparative aspects of electrophilic additions to alkynes, participation of allenyl bonds in solvolyses, and vinyl cations generated through diazonium ions. The nature of the cationic intermediates, migrations across the double bond, thiirenium ions, and species related to vinyl cations are likewise elaborated. This publication is beneficial to chemists and researchers concerned with vinyl cations.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Anonim
Publisher : Newnes
Release : 2013-06-25
ISBN : 0444626328
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products. Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable resource for natural products and medicinal chemistry

Dynamic Stereochemistry of Chiral Compounds

Dynamic Stereochemistry of Chiral Compounds Book
Author : Christian Wolf
Publisher : Royal Society of Chemistry
Release : 2008
ISBN : 0854042466
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

A comprehensive overview of fundamental concepts of asymmetric synthesis along with in-depth discussion. Recent developments that address important synthetic challenges are presented and highlighted with hundreds of examples.

Target Organ Toxicity

Target Organ Toxicity Book
Author : Cohen
Publisher : CRC Press
Release : 1986-08-31
ISBN : 9780849357756
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.

Target Organ Toxicity

Target Organ Toxicity Book
Author : Gerald M. Cohen
Publisher : CRC Press
Release : 2019-07-17
ISBN : 1000694194
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

First published in 1986: The purpose of these volumes is to provide a valuable reference for established investigators and postgraduate students in toxicology.

Target Organ Toxicity Volume I

Target Organ Toxicity  Volume I Book
Author : Gerald M. Cohen
Publisher : CRC Press
Release : 2020-01-29
ISBN : 1000714543
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.

Organometallic Chemistry of the Transition Elements

Organometallic Chemistry of the Transition Elements Book
Author : Florian P. Pruchnik
Publisher : Springer Science & Business Media
Release : 2013-06-29
ISBN : 1489920765
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Organometallic chemistry belongs to the most rapidly developing area of chemistry today. This is due to the fact that research dealing with the structure of compounds and chemical bonding has been greatly intensified in recent years. Additionally, organometallic compounds have been widely utilized in catalysis, organic synthesis, electronics, etc. This book is based on my lectures concerning basic organometallic chemistry for fourth and fifth year chemistry students and on my lectures concerning advanced organometallic chemistry and homogeneous catalysis for Ph.D. graduate students. Many recent developments in the area of organometallic chemistry as weIl as homogeneous catalysis are presented. Essential research results dealing with a given class of organometallic compounds are discussed briefly. Results of physicochemical research methods of various organometallic compounds as weIl as their synthesis, properties, structures, reactivities, and applications are discussed more thoroughly. The selection of tabulated data is arbitrary because, often, it has been impossible to avoid omissions. Nevertheless, these data can be very helpful in understanding properties of organometaIlic compounds and their reactivities. All physical data are given in SI units; the interatomic distances are given in pm units in figures and tables. I am indebted to Professor S. A. Duraj for translating and editing this book. His remarks, discussions, and suggestions are greatly appreciated. I also express gratitude to Virginia E. Duraj for editing and proofreading.

Ball Milling Towards Green Synthesis

Ball Milling Towards Green Synthesis Book
Author : Brindaban Ranu,Achim Stolle
Publisher : Royal Society of Chemistry
Release : 2014-11-26
ISBN : 1782621989
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Ball milling has emerged as a powerful tool over the past few years for effecting chemical reactions by mechanical energy. Allowing a variety of reactions to occur at ambient temperatures and in solvent-free conditions, ball milling presents a greener route for many chemical processes. Compared to the use of microwave and ultrasound as energy sources for chemical reactions, ball milling is not as familiar to chemists and yet it holds great potential. This book will introduce practicing chemists to the technique and will highlight its importance for green transformations. Current applications of ball milling will be covered in detail as well as its origin, recent developments and future scope, challenges and prospects. Chemical transformations covered include carbon-carbon and carbon-heteroatom bond formation, oxidation by solid oxidants, asymmetric organo-catalytic reactions, dehydrogenative coupling, peptide syntheses and polymeric material syntheses. The book will provide a valuable guide for organic, inorganic and organometallic chemists, material scientists, polymer scientists, reaction engineers and postgraduate students in chemistry.

Organic Reaction Mechanisms

Organic Reaction Mechanisms Book
Author : Michael Edenborough
Publisher : CRC Press
Release : 2017-12-21
ISBN : 1482295342
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This text is designed to teach students how to write organic reaction mechanisms. It starts from the absolute basics - counting the numbers of electrons around a simple atom. Then, in small steps, the text progresses to advanced mechanisms. the end, all the major mechanistic routes have been covered. The text is in the form of interactive sections, which are designed to facilitate the assimilation of the information conveyed, so that by the end the student should already know the contents without the need for extensive revision.

The Art of Writing Reasonable Organic Reaction Mechanisms

The Art of Writing Reasonable Organic Reaction Mechanisms Book
Author : Robert B. Grossman
Publisher : Springer Science & Business Media
Release : 2007-07-31
ISBN : 0387954686
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Intended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and "common error alerts" are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set.