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Realizing The Promise Of Precision Medicine

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Realizing the Promise of Precision Medicine

Realizing the Promise of Precision Medicine Book
Author : Paul Cerrato,John Halamka
Publisher : Academic Press
Release : 2017-08-24
ISBN : 0128116366
Language : En, Es, Fr & De

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Book Description :

Realizing the Promise of Precision Medicine: The Role of Patient Data, Mobile Technology, and Consumer Engagement explains the potential of personalized medicine and the value of those approaches in making that potential a reality. The book helps transform one-size-fits-all healthcare into a system that focuses on individual needs and the unique needs of each family member, discussing topics such as U.S. sponsored precision medicine initiative, genomics, the role of electronic health records and mobile medicine, patient engagement and empowerment, health information exchange and patient data protection. In addition, the book discusses the barriers and limitations of precision medicine and how to overcome them. Readers will find valuable insights into how big data, patient engagement, mobile technology, and genomics help individualize medical care and offer a pathway to help detect many undiscovered causes of diseases. Provides drawings and flow charts to help readers visualize the breadth and depth of precision medicine Includes sidebars with more details on specific topics for a complementary, deeper understanding of the main text Uses case studies to turn abstract concepts into flesh and blood examples of how personalized medicine benefits patients

Continuing Americas Leadership

Continuing Americas Leadership Book
Author : United States. Congress,Committee on Health Education Labor and Pensions,United States Senate
Publisher : Unknown
Release : 2017-08-20
ISBN : 9781974656646
Language : En, Es, Fr & De

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Book Description :

Continuing America's leadership : realizing the promise of precision medicine for patients : hearing of the Committee on Health, Education, Labor, and Pensions, United States Senate, One Hundred Fourteenth Congress, first session ... May 5, 2015.

Continuing America s leadership

Continuing America s leadership Book
Author : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions
Publisher : Unknown
Release : 2017
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Continuing America s leadership book written by United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Transformative Power of Mobile Medicine

The Transformative Power of Mobile Medicine Book
Author : Paul Cerrato,John Halamka
Publisher : Academic Press
Release : 2019-01-23
ISBN : 0128149248
Language : En, Es, Fr & De

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Book Description :

The Transformative Power of Mobile Medicine: Leveraging Innovation, Seizing Opportunities, and Overcoming Obstacles of mHealth addresses the rapid advances taking place in mHealth and their impact on clinicians and patients. It provides guidance on reliable mobile health apps that are based on sound scientific evidence, while also offering advice on how to stay clear of junk science. The book explores the latest developments, including the value of blockchain, the emerging growth of remote sensors in chronic patient care, the potential use of Amazon Alexa and Google Assistant as patient bedside assistants, the use of Amazon’s IoT button, and much more. This book enables physicians and nurses to gain a deep understanding of the strengths and weaknesses of mobile health and helps them choose evidence-based mobile medicine tools to improve patient care. Provides clinicians and technologists with an update on the latest mobile health initiatives and tools, including the work done at Beth Israel Deaconess Medical Center/Harvard Medical School Encompasses case studies with real-world examples to turn abstract concepts into flesh and blood examples of how mHealth benefits the public Presents drawings, graphics and flow charts to help readers visualize the functionality and value of mobile medicine

Economic Dimensions of Personalized and Precision Medicine

Economic Dimensions of Personalized and Precision Medicine Book
Author : Ernst R. Berndt,Dana P. Goldman,John Rowe
Publisher : University of Chicago Press
Release : 2019-04-22
ISBN : 022661123X
Language : En, Es, Fr & De

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Book Description :

Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.

Law and Economics of Personalized Medicine

Law and Economics of Personalized Medicine Book
Author : Karin Bosshard
Publisher : Springer
Release : 2018-05-14
ISBN : 3658220740
Language : En, Es, Fr & De

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Book Description :

The book adds to the discussion about strategic approaches towards the translation of personalized medicine into clinical practice. It stresses the importance of non-science related, institutional barriers. A Law and Economics perspective is applied in order to examine the incentives induced by the barriers. An applied part identifies and evaluates policy levers to foster the translation of personalized medicine into Swiss clinical practice.

Relevance of Health Literacy to Precision Medicine

Relevance of Health Literacy to Precision Medicine Book
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Roundtable on Health Literacy
Publisher : National Academies Press
Release : 2016-12-04
ISBN : 0309447321
Language : En, Es, Fr & De

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Book Description :

On January 20, 2015, President Obama announced the Precision Medicine Initiative (PMI) in his State of the Union address. The PMI, by developing new approaches for detecting, measuring, and analyzing a wide range of biomedical information including molecular, genomic, cellular, clinical, behavioral, physiological, and environmental parameters, is intended to enable a new era of medicine in which researchers, providers, and patients work together to develop individualized care. Part of this effort included the creation of a national, large-scale research participant group, or cohort. The PMI Cohort Program is aimed at extending precision medicine to many diseases, including both rare and common diseases such as diabetes, heart disease, Alzheimer's disease, obesity, and mental illnesses such as depression, bipolar disorder, and schizophrenia, by building a national research cohort of 1 million or more U.S. participants. An important challenge to assembling the PMI Cohort will be to reach individuals who are socioeconomically disadvantaged. Individuals who are socioeconomically disadvantaged have lower health literacy; often belong to racial, ethnic, and minority communities; and are often less likely to participate in research studies and biorepositories. To explore possible strategies and messaging designs, the Roundtable on Health Literacy formed an ad hoc committee charged with planning and conducting a 1-day public workshop on the intersection of health literacy and precision medicine. The workshop participants discussed a variety of topics including an overview of precision medicine and its potential, the relevance of health literacy to the success of precision medicine efforts, and perspectives and understanding of different groups, such as health care providers, consumers, and insurers. This publication summarizes the presentations and discussions from the workshop.

Reinventing Clinical Decision Support

Reinventing Clinical Decision Support Book
Author : Paul Cerrato,John Halamka
Publisher : Taylor & Francis
Release : 2020-01-15
ISBN : 1000055558
Language : En, Es, Fr & De

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Book Description :

This book takes an in-depth look at the emerging technologies that are transforming the way clinicians manage patients, while at the same time emphasizing that the best practitioners use both artificial and human intelligence to make decisions. AI and machine learning are explored at length, with plain clinical English explanations of convolutional neural networks, back propagation, and digital image analysis. Real-world examples of how these tools are being employed are also discussed, including their value in diagnosing diabetic retinopathy, melanoma, breast cancer, cancer metastasis, and colorectal cancer, as well as in managing severe sepsis. With all the enthusiasm about AI and machine learning, it was also necessary to outline some of criticisms, obstacles, and limitations of these new tools. Among the criticisms discussed: the relative lack of hard scientific evidence supporting some of the latest algorithms and the so-called black box problem. A chapter on data analytics takes a deep dive into new ways to conduct subgroup analysis and how it’s forcing healthcare executives to rethink the way they apply the results of large clinical trials to everyday medical practice. This re-evaluation is slowly affecting the way diabetes, heart disease, hypertension, and cancer are treated. The research discussed also suggests that data analytics will impact emergency medicine, medication management, and healthcare costs. An examination of the diagnostic reasoning process itself looks at how diagnostic errors are measured, what technological and cognitive errors are to blame, and what solutions are most likely to improve the process. It explores Type 1 and Type 2 reasoning methods; cognitive mistakes like availability bias, affective bias, and anchoring; and potential solutions such as the Human Diagnosis Project. Finally, the book explores the role of systems biology and precision medicine in clinical decision support and provides several case studies of how next generation AI is transforming patient care.

Problem Solving through Precision Oncology

Problem Solving through Precision Oncology Book
Author : Peter Selby
Publisher : EBN Health, an imprint of Evidence-based Networks Ltd
Release : 2016-11-07
ISBN : 184692653X
Language : En, Es, Fr & De

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Book Description :

Winner of the BMA Oncology Book of the Year Award. This practical learning and reference handbook provides an overview of the latest progress in the developing field of precision oncology, plus a ground breaking collection of case studies ("Problems") showing precision oncology in practice. The book includes a clear, readable summary of developments, alongside real-life case studies, providing a valuable update for all involved in the oncology community. The editors lead research and clinical teams at four UK centres of excellence in the field.

The Genetic and Environmental Basis for Diseases in Understudied Populations

The Genetic and Environmental Basis for Diseases in Understudied Populations Book
Author : Nicola Mulder,Zané Lombard,Mayowa Ojo Owolabi,Solomon Fiifi Ofori-Acquah
Publisher : Frontiers Media SA
Release : 2020-12-15
ISBN : 2889661687
Language : En, Es, Fr & De

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Book Description :

Download The Genetic and Environmental Basis for Diseases in Understudied Populations book written by Nicola Mulder,Zané Lombard,Mayowa Ojo Owolabi,Solomon Fiifi Ofori-Acquah, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Personalized Medicine in Healthcare Systems

Personalized Medicine in Healthcare Systems Book
Author : Nada Bodiroga-Vukobrat,Daniel Rukavina,Krešimir Pavelić,Gerald G. Sander
Publisher : Springer
Release : 2019-08-02
ISBN : 3030164659
Language : En, Es, Fr & De

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Book Description :

This book gathers scientific contributions on comprehensive approaches to personalized medicine. In a systematic and clear manner, it provides extensive information on the methodological, technological, and clinical aspects of high-throughput analytics, nanotechnology approaches, microbiota/human interactions, in-vitro fertilization and preimplantation, and various diseases like cancer.Moreover, the book analyzes the social and legal aspects of social security systems, healthcare systems and EU law – e.g. the role of solidarity, regulatory possibilities and obstacles, justice and equality, privacy/disclosure of data, and the right to know – from an interdisciplinary perspective. Lastly, it explores the economical and ethical context in the fields of business models, intellectual property issues, the patient/physician relationship, and price discrimination.

Socio economics of Personalized Medicine in Asia

Socio economics of Personalized Medicine in Asia Book
Author : Shirley Sun
Publisher : Routledge
Release : 2016-07-01
ISBN : 1134989199
Language : En, Es, Fr & De

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Book Description :

The second decade of the twenty-first century has witnessed a surging interest in personalized medicine with the concomitant promise to enable more precise diagnosis and treatment of disease and illness, based upon an individual’s unique genetic makeup. In this book, my goal is to contribute to a growing body of literature on personalized medicine by tracing and analyzing how this field has blossomed in Asia. In so doing, I aim to illustrate how various social and economic forces shape the co-production of science and social order in global contexts. This book shows that there are inextricable transnational linkages between developing and developed countries and also provides a theoretically guided and empirically grounded understanding of the formation and usage of particular racial and ethnic human taxonomies in local, national and transnational settings. The Open Access version of this book, available at http://www.taylorfrancis.com/doi/view/10.4324/9781315537177 has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.

Out of the Crucible

Out of the Crucible Book
Author : Arthur Kellermann,Eric Elster,Charles Babington,Racine Harris
Publisher : Government Printing Office
Release : 2017
ISBN : 9780160941795
Language : En, Es, Fr & De

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Book Description :

Out of the Crucible: How the U.S. Military Transformed Combat Casualty Care in Iraq and Afghanistan edited by Arthur L. Kellermann, MD and MPH, and Eric Elster, MD is now available by the US Army, Borden Institute. This comprehensive resource, part of the renowned Textbooks of Military Medicine series, documents one of the most extraordinary achievements in the history of American medicine - the dramatic advances in combat casualty care developed during Operations Enduring Freedom and Operation Iraqi Freedom. Each chapter is written by one or more military health professionals who played an important role in bringing the advancement to America's military health system. Written in plain English and amply illustrated with informative figures and photographs, Out of the Crucible engages and informs the American public and policy makers about how America's military health system, devised, tested and widely adopted numerous inventions, innovations, technologies that collectively produced the highest survival rate from battlefield trauma in the history of warfare.

Out of the Crucible

Out of the Crucible Book
Author : Arthur L. Kellermann,Eric Elster,Borden Institute
Publisher : Government Printing Office
Release : 2018-01-30
ISBN : 9780160943621
Language : En, Es, Fr & De

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Book Description :

Out of the Crucible: How the U.S. Military Transformed Combat Casualty Care in Iraq and Afghanistan edited by Arthur L. Kellermann, MD and MPH, and Eric Elster, MD is now available by the US Army, Borden Institute. This comprehensive resource, part of the renowned Textbooks of Military Medicine series, documents one of the most extraordinary achievements in the history of American medicine - the dramatic advances in combat casualty care developed during Operations Enduring Freedom and Operation Iraqi Freedom. Each chapter is written by one or more military health professionals who played an important role in bringing the advancement to America's military health system. Written in plain English and amply illustrated with informative figures and photographs, Out of the Crucible engages and informs the American public and policy makers about how America's military health system, devised, tested and widely adopted numerous inventions, innovations, technologies that collectively produced the highest survival rate from battlefield trauma in the history of warfare.

Advances in Multidisciplinary Medical Technologies Engineering Modeling and Findings

Advances in Multidisciplinary Medical Technologies     Engineering  Modeling and Findings Book
Author : Abdeldjalil Khelassi,Vania Vieira Estrela
Publisher : Springer Nature
Release : 2020-11-07
ISBN : 3030575527
Language : En, Es, Fr & De

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Book Description :

This book collects the proceedings of the International Congress on Health Sciences and Medical Technologies (ICHSMT), held in Tlemcen, Algeria, from December 5 to 7, 2019. The proceedings present a forum for the latest projects and research in scientific and technological development with an emphasis on smart healthcare system design and future technologies. ICHSMT brings together researchers, students, and professionals from the healthcare, corporate, and academic sectors. It includes a far-reaching program supported by a variety of technical tracks that seek to promote medical technologies and innovation at a nationwide level.

Precision Haematological Cancer Medicine

Precision Haematological Cancer Medicine Book
Author : Tariq Mughal
Publisher : CRC Press
Release : 2018-09-27
ISBN : 1498747019
Language : En, Es, Fr & De

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Book Description :

Many experts now consider genetic evaluation to be pivotal for the optimal diagnosis, classification, risk stratification, and therapeutic decision-making for persons diagnosed with blood cancer. This new text specifically focuses on the genetic alterations essential for establishing diagnosis and assesses how they might impact the precision oncology standard of care. Providing an authoritative review of the state of the art, this is essential reading for physicians, hematologists, and oncologists for optimal management of individual patients.

Biotechnology Entrepreneurship

Biotechnology Entrepreneurship Book
Author : Craig Shimasaki
Publisher : Academic Press
Release : 2020-05-16
ISBN : 0128155868
Language : En, Es, Fr & De

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Book Description :

This second edition of Biotechnology Entrepreneurship: Leading, Managing, and Commercializing Innovative Technologies is an authoritative, easy-to-read guide covering biotechnology entrepreneurship and the process of commercializing innovative biotechnology products. This best practice resource is for professional training programs, individuals starting a biotech venture, and for managers and experienced practitioners leading biotech enterprises. It is a valuable resource for those working at any level in the biotech industry, and for professionals who support and provide essential resources and services to the biotech industry. This practical, “how-to book is written by seasoned veterans experienced in each of the operational functions essential for starting, managing, and leading a successful biotech company. Biotechnology Entrepreneurship explains the biotech business components and underlying strategies, interspersed with practical lessons from successful biotech entrepreneurs, educators, and experienced practitioners. These veteran contributors share their insights on how to be successful in this challenging but exciting industry. Subjects range from technology licensing and translating an idea into a viable business, forming your legal company entity, securing angel and venture capital, navigating product development, FDA regulatory approval, and biomanufacturing. This book is a user-friendly guide to decision-making and overall strategy written as a hands-on management tool for leaders and managers of these dynamic biotechnology ventures. If you are contemplating starting a biotech company, are a manager at any level, a seasoned veteran, or service provider in the biotech industry, this book is a “must read. This second edition includes several new chapters on topics such as: What you need to know about valuation and term sheets Investor presentations and what you need in a biotech investor pitch deck Mentorship and why you need mentors Artificial intelligence applications in biotech and pharma Common biotech entrepreneur mistakes and how to avoid them

Protecting Patient Information

Protecting Patient Information Book
Author : Paul Cerrato
Publisher : Syngress
Release : 2016-04-14
ISBN : 012804411X
Language : En, Es, Fr & De

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Book Description :

Protecting Patient Information: A Decision-Maker's Guide to Risk, Prevention, and Damage Control provides the concrete steps needed to tighten the information security of any healthcare IT system and reduce the risk of exposing patient health information (PHI) to the public. The book offers a systematic, 3-pronged approach for addressing the IT security deficits present in healthcare organizations of all sizes. Healthcare decision-makers are shown how to conduct an in-depth analysis of their organization’s information risk level. After this assessment is complete, the book offers specific measures for lowering the risk of a data breach, taking into account federal and state regulations governing the use of patient data. Finally, the book outlines the steps necessary when an organization experiences a data breach, even when it has taken all the right precautions. Written for physicians, nurses, healthcare executives, and business associates who need to safeguard patient health information Shows how to put in place the information security measures needed to reduce the threat of data breach Teaches physicians that run small practices how to protect their patient’s data Demonstrates to decision-makers of large and small healthcare organizations the urgency of investing in cybersecurity

Advances in Molecular Pathology E Book 2021

Advances in Molecular Pathology  E Book 2021 Book
Author : Gregory J. Tsongalis
Publisher : Elsevier Health Sciences
Release : 2021-10-13
ISBN : 0323813364
Language : En, Es, Fr & De

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Book Description :

Advances in Molecular Pathology is an annual review publication that covers the current practices and latest developments in the field of Molecular Pathology. Each issue is divided into sections for comprehensive coverage of all subspecialty areas within molecular pathology, including, Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid Tumors, and special topics on COVID-19. The Editor-in-Chief of the publication is Dr. Gregory Tsongalis, a leading expert in the field. Topics covered this year include but are not limited to: Phenotype Association and Variant Pathogenicity Prediction Tools in Genomic Analysis; The application of noninvasive prenatal screening to detect copy number variations; Next generation cytogenomics using optical mapping; Review of molecular in APL; NGS for MRD in acute leukemia; Review of emerging technologies as they pertain to infectious disease testing; Germline genetic variants that predict drug response; Nutrigenomics; PGx of hypertension; Genomic data for blood typing, specifically both through NGS and arrays; Preanalytic Variables and Tissue Stewardship for Reliable Next-Generation Sequencing (NGS) Clinical Analysis; and Cell-free nucleic acids in cancer: Current approaches, challenges, and future directions.

Informed Consent and Health

Informed Consent and Health Book
Author : Thierry Vansweevelt,Nicola Glover-Thomas
Publisher : Edward Elgar Publishing
Release : 2020-04-24
ISBN : 1788973429
Language : En, Es, Fr & De

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Book Description :

Informed consent is the legal instrument that purports to protect an individual’s autonomy and defends against medical arbitrariness. This illuminating book investigates our evolving understanding of informed consent from a range of comparative and international perspectives, demonstrating the diversity of its interpretations around the world. Chapters offer a nuanced analysis of the problems that impede the understanding and implementation of the concept of informed consent and explore the contemporary challenges that continue to hinder both the patient and the medical community.