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Quantitative Mri Of The Spinal Cord

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Quantitative MRI of the Spinal Cord

Quantitative MRI of the Spinal Cord Book
Author : Julien Cohen-Adad,Claudia Wheeler-Kingshott
Publisher : Academic Press
Release : 2014-01-16
ISBN : 0123972825
Language : En, Es, Fr & De

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Book Description :

Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory’s applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord. Chapters authored by international experts in the field of MRI of the spinal cord Contains “cooking recipes —examples of imaging parameters for each quantitative technique—designed to aid researchers and clinicians in using them in practice Ideal for clinical settings

Quantitative MRI of the Brain

Quantitative MRI of the Brain Book
Author : Mara Cercignani,Nicholas G. Dowell,Paul S. Tofts
Publisher : CRC Press
Release : 2018-01-12
ISBN : 1315363569
Language : En, Es, Fr & De

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Book Description :

Building on the success of the first edition of this book, the winner of the 2004 British Medical Association Radiology Medical Book Competition, Quantitative MRI of the Brain: Principles of Physical Measurement gives a unique view on how to use an MRI machine in a new way. Used as a scientific instrument it can make measurements of a myriad of physical and biological quantities in the human brain and body. For each small tissue voxel, non-invasive information monitors how tissue changes with disease and responds to treatment. The book opens with a detailed exposition of the principles of good practice in quantification, including fundamental concepts, quality assurance, MR data collection and analysis and improved study statistical power through minimised instrumental variation. There follow chapters on 14 specific groups of quantities: proton density, T1, T2, T2*, diffusion, advanced diffusion, magnetisation transfer, CEST, 1H and multi-nuclear spectroscopy, DCE-MRI, quantitative fMRI, arterial spin-labelling and image analysis, and finally a chapter on the future of quantification. The physical principles behind each quantity are stated, followed by its biological significance. Practical techniques for measurement are given, along with pitfalls and examples of clinical applications. This second edition of this indispensable 'how to' manual of quantitative MR shows the MRI physicist and research clinician how to implement these techniques on an MRI scanner to understand more about the biological processes in the patient and physiological changes in healthy controls. Although focussed on the brain, most techniques are applicable to characterising tissue in the whole body. This book is essential reading for anyone who wants to use the gamut of modern quantitative MRI methods to measure the effects of disease, its progression, and its response to treatment. Features: The first edition was awarded the book prize for Radiology by the British Medical Association in 2004 Written by an authority in the field: Professor Tofts has an international reputation for quantification in MRI Gives specific ‘how to’ information for implementation of MRI measurement sequence techniques

Quantitative MRI of the Brain

Quantitative MRI of the Brain Book
Author : Paul Tofts
Publisher : John Wiley & Sons
Release : 2005-08-19
ISBN : 0470869496
Language : En, Es, Fr & De

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Book Description :

2004 BMA Medical Book Competition Winner (Radiology category) “This is an exciting book, with a new approach to use of the MRI scanner. It bridges the gap between clinical research and general neuro-radiological practice. It is accessible to the clinical radiologist, and yet thorough in its treatment of the underlying physics and of the science of measurement. It is likely to become a classic.” British Medical Association This indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. It contains both the methodology and clinical applications, reflecting the increasing interest in quantitative MR in studying disease and its progression. The editor is an MR scientist with an international reputation for high quality research The contributions are written jointly by MR physicists and MR clinicians, producing a practical book for both the research and medical communities A practical book for both the research and medical communities “Paul Tofts has succeeded brilliantly in capturing the essence of what needs to become the future of radiology in particular, and medicine in general – quantitative measurements of disease.” Robert I. Grossman, M.D. New York, University School of Medicine (from the Foreword)

Quantitative Magnetic Resonance Imaging

Quantitative Magnetic Resonance Imaging Book
Author : Nicole Seiberlich,Vikas Gulani,Adrienne Campbell-Washburn,Steven Sourbron,Mariya Ivanova Doneva,Fernando Calamante,Houchun Harry Hu
Publisher : Academic Press
Release : 2020-11-27
ISBN : 0128170581
Language : En, Es, Fr & De

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Book Description :

Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Spinal Cord Injury

Spinal Cord Injury Book
Author : Joost Verhaagen,John W. McDonald III
Publisher : Newnes
Release : 2012-12-31
ISBN : 0444535071
Language : En, Es, Fr & De

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Book Description :

Handbook of Clinical Neurology: Spinal Cord Injury summarizes advances in the clinical diagnosis, monitoring, prognostication, treatment, and management of spinal cord injuries. More specifically, it looks at new and important developments in areas such as high-resolution noninvasive neuroimaging, surgery, and electrical stimulation of motor, respiratory, bladder, bowel, and sexual functions. It also reviews the latest insights into spontaneous regeneration and recovery of function following rehabilitation, with emphasis on novel therapeutic strategies, such as gene therapy, transcranial stimulation, brain-machine interfaces, pharmacological approaches, molecular target discovery, and the use of olfactory ensheathing cells, stem cells, and precursor cells. Organized in five sections, the book begins with an overview of the development, maturation, biomechanics, and anatomy of the spinal cord before proceeding with a discussion of clinical diagnosis and prognosis as well as natural recovery, ambulation, and function following spinal cord injury. It then examines clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury; medical, surgical and rehabilitative management of spinal cord trauma; and some new approaches for improving recovery in patients, including restoration of function by electrical stimulation, locomotor training, and the use of robotics. Other chapters cover cell transplantation, artificial scaffolds, experimental pharmacological interventions, and molecular and combinatorial strategies for repairing the injured spinal cord. This volume should be of interest to neuroscience and clinical neurology research specialists and practicing neurologists. Comprehensive coverage of the latest scientific understanding of spinal cord injuries Detailed coverage of current treatment best practices and potential future treatments Connects leading edge research programs to future treatment opportunities

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma Book
Author : Michael Fehlings,Brian Kwon,Alexander Vaccaro,F. Cumhur Oner
Publisher : Academic Press
Release : 2022-02-17
ISBN : 0128198362
Language : En, Es, Fr & De

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Book Description :

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout. These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma. Contains contributions by international authors Covers recent clinical trial advancements and findings and updates on ongoing trials Presents an overview of clinical practice guidelines for the management of traumatic spinal cord injury featured Provides the reader with insights regarding the translation of research from bench to bedside and the skills needed to understand the translational pathway using real-life examples

The Neuroscience of Spinal Cord Injury

The Neuroscience of Spinal Cord Injury Book
Author : Rajkumar Rajendram,Victor R. Preedy,Colin R. Martin
Publisher : Academic Press
Release : 2022-05-27
ISBN : 0323995764
Language : En, Es, Fr & De

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Book Description :

Diagnosis and Treatment of Spinal Cord Injury will enhance readers’ understanding of the complexities of the diagnosis and management of spinal cord injuries. Featuring chapters on drug delivery, exercise, and rehabilitation, this volume discusses in detail the impact of the clinical features, diagnosis, management, and long-term prognosis of spinal cord injuries on the lives of those affected. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand spinal cord injuries. Spinal injury affects about 10 million people annually worldwide, impacting on the family unit and causing lifelong disabilities, with varied symptoms including paresthesia, spasticity, loss of motor control, and often severe pain. Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury will enhance readers’ understanding of the biological and psychological effects of spinal cord injury. Featuring chapters on gene expression, metabolic effects, and behavior, this volume discusses in detail the impact of spinal cord injury to better understand the underlying pathways and processes. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries. Diagnosis and Treatment of Spinal Cord Injury: Covers both the diagnosis and treatment of spinal cord injury Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding Features chapters on epidemiology and pain Includes MRI usage, biomarkers, and stem cell and gene therapy for management of spinal cord injury Discusses pain reduction, drug delivery, and rehabilitation Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury: Summarizes the neuroscience of spinal cord injury, including cellular and molecular biology Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding Features chapters on signaling and hormonal events Includes plasticity and gene expression Examines health and stress behaviors after spinal cord injury

Cellular Molecular Physiological and Behavioral Aspects of Spinal Cord Injury

Cellular  Molecular  Physiological  and Behavioral Aspects of Spinal Cord Injury Book
Author : Rajkumar Rajendram,Victor R. Preedy,Colin R. Martin
Publisher : Academic Press
Release : 2022-05-10
ISBN : 0128224282
Language : En, Es, Fr & De

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Book Description :

Spinal injury affects about 10 million people annually worldwide, impacting on the family unit and causing lifelong disabilities, with varied symptoms including paresthesia, spasticity, loss of motor control, and often severe pain. Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury will enhance readers’ understanding of the biological and psychological effects of spinal cord injury. Featuring chapters on gene expression, metabolic effects, and behavior, this volume discusses in detail the impact of spinal cord injury to better understand the underlying pathways and processes. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries. Summarizes the neuroscience of spinal cord injury, including cellular and molecular biology Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding Features chapters on signaling and hormonal events Includes plasticity and gene expression Examines health and stress behaviors after spinal cord injury

Quantitative MRI in Cancer

Quantitative MRI in Cancer Book
Author : Thomas E. Yankeelov,David R. Pickens,Ronald R. Price
Publisher : Taylor & Francis
Release : 2011-09-13
ISBN : 1439820589
Language : En, Es, Fr & De

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Book Description :

Propelling quantitative MRI techniques from bench to bedside, Quantitative MRI in Cancer presents a range of quantitative MRI methods for assessing tumor biology. It includes biophysical and theoretical explanations of the most relevant MRI techniques as well as examples of these techniques in cancer applications. The introductory part of the book covers basic cancer biology, theoretical aspects of NMR/MRI physics, and the hardware required to form MR images. Forming the core of the book, the next three parts illustrate how to characterize tissue properties with endogenous and exogenous contrast mechanisms and discuss common image processing techniques relevant for cancer. The final part explores emerging areas of MR cancer characterization, including radiation therapy planning, cellular and molecular imaging, pH imaging, and hyperpolarized MR. Each of the post-introductory chapters describes the salient qualitative and quantitative aspects of the techniques before proceeding to preclinical and clinical applications. Each chapter also contains references for further study. Leading the way toward more personalized medicine, this text brings together existing and emerging quantitative MRI techniques for assessing cancer. It provides a self-contained overview of the theoretical and experimental essentials and state of the art in cancer MRI.

Computed Tomography Magnetic Resonance Imaging Of The Whole Body E Book

Computed Tomography   Magnetic Resonance Imaging Of The Whole Body E Book Book
Author : John R. Haaga,Daniel Boll
Publisher : Elsevier Health Sciences
Release : 2016-06-06
ISBN : 0323278167
Language : En, Es, Fr & De

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Book Description :

Over 5,200 high quality CT, MR, and hybrid technology images in one definitive reference. For the radiologist who needs information on the latest cutting-edge techniques in rapidly changing imaging technologies, such as CT, MRI, and PET/CT, and for the resident who needs a comprehensive resource that gives a broad overview of CT and MRI capabilities. Brand-new team of new international associate editors provides a unique global perspective on the use of CT and MRI across the world. Completely revised in a new, more succinct presentation without redundancies for faster access to critical content. Vastly expanded section on new MRI and CT technology keeps you current with continuously evolving innovations.

Cervical Myelopathy An Issue of Neurosurgery Clinics of North America E Book

Cervical Myelopathy  An Issue of Neurosurgery Clinics of North America  E Book Book
Author : Michael G. Fehlings,Junichi Mizuno
Publisher : Elsevier Health Sciences
Release : 2017-12-01
ISBN : 0323570666
Language : En, Es, Fr & De

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Book Description :

This issue of Neurosurgery Clinics, edited by Dr. Michael G. Fehlings and Dr. Junichi Mizuno, focuses on Cervical Myelopathy. Topics include, but are not limited to, Epidemiology and overview of the clinical spectrum of degenerative cervical myelopathy; Pathobiology of degenerative cervical myelopathy; Natural history of degenerative cervical myelopathy; Imaging evaluation of degenerative cervical myelopathy: current state of the art and future directions; Pathophysiology of CPPD and OYL(OLF); Radiological evaluation of OPLL with dural ossification; Relationship of OALL, OPLL and OYL (OLF); Importance of sagittal alignment of the cervical spine in the management of degenerative cervical myelopathy; Anterior cervical options to manage degenerative cervical myelopathy; Laminectomy with or without fusion to manage degenerative cervical myelopathy; History and evolution of laminoplasty; Prediction of outcomes in managing degenerative cervical myelopathy; Neurological complications in managing degenerative cervical myelopathy; Options to manage the patient with mild degenerative cervical myelopathy; Management of the patient with cervical cord compression but no evidence of myelopathy; Intraoperative neurophysiological monitoring for CDD; Future Directions and New Technology, and more!

Advances in Central Nervous System Research and Treatment 2013 Edition

Advances in Central Nervous System Research and Treatment  2013 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2013-06-21
ISBN : 1481669850
Language : En, Es, Fr & De

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Book Description :

Advances in Central Nervous System Research and Treatment: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Meninges. The editors have built Advances in Central Nervous System Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Meninges in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Central Nervous System Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Adult and Pediatric Spine Trauma An Issue of Neurosurgery Clinics of North America E Book

Adult and Pediatric Spine Trauma  An Issue of Neurosurgery Clinics of North America  E Book Book
Author : Douglas L. Brockmeyer,Andrew T. Dailey
Publisher : Elsevier Health Sciences
Release : 2016-11-26
ISBN : 0323482848
Language : En, Es, Fr & De

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Book Description :

This issue will focus on both adult and pediatric spine trauma. Featured articles are as follows: Pharmacologic Treatment of SCI; Classification of Adult Subaxial Cervical Trauma; Classification and Management of Pediatric Craniocervical Injuries; Classification and Management of Pediatric Subaxial Injuries; Classification of Adult Thoracolumbar Injuries; Management of Pediatric Thoracolumber Injuries; Treatment of Odontoid Fractures in the Aging Population; Treatment of Facet Fractures in the Cervical Spine; and many more!

Imaging of Neuromuscular Diseases

Imaging of Neuromuscular Diseases Book
Author : Massimiliano Filosto,Anna Pichiecchio,Jordi Diaz-Manera,Francesco Santini
Publisher : Frontiers Media SA
Release : 2022-01-20
ISBN : 2889741109
Language : En, Es, Fr & De

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Book Description :

Download Imaging of Neuromuscular Diseases book written by Massimiliano Filosto,Anna Pichiecchio,Jordi Diaz-Manera,Francesco Santini, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Advances in Spinal Cord Epidural Stimulation for Motor and Autonomic Functions Recovery After Severe Spinal Cord Injury

Advances in Spinal Cord Epidural Stimulation for Motor and Autonomic Functions Recovery After Severe Spinal Cord Injury Book
Author : Enrico Rejc,Ronaldo M. Ichiyama,Claudia A. Angeli
Publisher : Frontiers Media SA
Release : 2022-02-14
ISBN : 2889743918
Language : En, Es, Fr & De

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Book Description :

Download Advances in Spinal Cord Epidural Stimulation for Motor and Autonomic Functions Recovery After Severe Spinal Cord Injury book written by Enrico Rejc,Ronaldo M. Ichiyama,Claudia A. Angeli, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Canine Intervertebral Disc Disease The Current State of Knowledge

Canine Intervertebral Disc Disease  The Current State of Knowledge Book
Author : Natasha J. Olby,Andrea Tipold
Publisher : Frontiers Media SA
Release : 2021-05-04
ISBN : 2889667405
Language : En, Es, Fr & De

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Book Description :

Download Canine Intervertebral Disc Disease The Current State of Knowledge book written by Natasha J. Olby,Andrea Tipold, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Multiple Sclerosis An Issue of Neurologic Clinics E Book

Multiple Sclerosis  An Issue of Neurologic Clinics  E Book Book
Author : Darin T. Okuda
Publisher : Elsevier Health Sciences
Release : 2017-11-27
ISBN : 0323569935
Language : En, Es, Fr & De

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Book Description :

This issue of Neurologic Clinics, edited by Dr. Darin T. Okuda, focuses on Multiple Sclerosis. Topics include, but are not limited to, Myelin and Axonal Repair Strategies in Multiple Sclerosis; Common Clinical and Imaging Conditions Misdiagnosed as Multiple Sclerosis; Topographical Model for Multiple Sclerosis: A Novel Approach to Understanding Clinical Phenotypes and Disease Activity; Incidental Anomalies Characteristic of CNS Demyelination: Radiologically Isolated Syndrome; Pediatric Multiple Sclerosis: From Recognition to Practical Clinical Management; Progressive Forms of Multiple Sclerosis: Distinct Entity or Time Dependent Phenomena; Advanced Symptom Management Strategies in Multiple Sclerosis, Ethnic Considerations and Multiple Sclerosis Disease Variability; The Dynamics of the Gut Microbiome in Multiple Sclerosis in Relation to Disease; Spinal Cord Imaging in Relation to Clinical Status in Multiple Sclerosis, and more.

Issues in CNS Diseases and Disorders 2013 Edition

Issues in CNS Diseases and Disorders  2013 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2013-05-01
ISBN : 1490108793
Language : En, Es, Fr & De

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Book Description :

Issues in CNS Diseases and Disorders / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Neuromuscular Disease. The editors have built Issues in CNS Diseases and Disorders: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neuromuscular Disease in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in CNS Diseases and Disorders: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Mammalian Spinal Cord

The Mammalian Spinal Cord Book
Author : Charles Watson,Gulgun Sengul,George Paxinos
Publisher : Academic Press
Release : 2021-12-22
ISBN : 0128141476
Language : En, Es, Fr & De

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Book Description :

The Mammalian Spinal Cord provides a comprehensive account of the anatomy and histology of the spinal cord. The text covers the cytoarchitecture, chemoarchitecture, motor neuron distribution, long tracts, autonomic outflow, and gene expression in the spinal cord. A feature of the book is the inclusion of segment-by-segment atlases of the spinal cords of rat, mouse, newborn mouse, marmoset, rhesus monkey, and human. This book is an essential reference for researchers studying the spinal cord. Includes full-color photographic images of Nissl-stained sections from every spinal cord segment in each of two rodent and three primate species, over 160 Nissl plates Contains comprehensively labeled diagrams to accompany each Nissl-stained section, over 160 diagrams Provides more than 500 photographic images of sections stained for AChE, ChAT, parvalbumin, NADPH- diaphorase, calretinin, or other markers to supplement the Nissl-stained images

Advances in Central Nervous System Research and Treatment 2011 Edition

Advances in Central Nervous System Research and Treatment  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464921296
Language : En, Es, Fr & De

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Book Description :

Advances in Central Nervous System Research and Treatment: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Central Nervous System. The editors have built Advances in Central Nervous System Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Central Nervous System in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Central Nervous System Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.