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Quantitative Magnetic Resonance Imaging

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Theory of Quantitative Magnetic Resonance Imaging

Theory of Quantitative Magnetic Resonance Imaging Book
Author : Hernán Jara
Publisher : World Scientific Publishing Company
Release : 2013-04-04
ISBN : 9814518387
Language : En, Es, Fr & De

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Book Description :

qMRI is a rapidly evolving scientific field of high current interest because it has the potential of radically changing the clinical and research practices of magnetic resonance imaging (MRI). This focuses solely on the theoretical aspects of qMRI, which are treated and analyzed at three different spatial scales, specifically: i) the quantum physics scale of individual spins; ii) the semi-classical physics scale of spin packets; and iii) the imaging scale of voxels. Topics are presented paying particular attention to theoretical unification and mathematical uniformity.

Quantitative Magnetic Resonance Imaging

Quantitative Magnetic Resonance Imaging Book
Author : Nicole Seiberlich,Vikas Gulani,Adrienne Campbell-Washburn,Steven Sourbron,Mariya Ivanova Doneva,Fernando Calamante,Houchun Harry Hu
Publisher : Academic Press
Release : 2020-11-27
ISBN : 0128170581
Language : En, Es, Fr & De

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Book Description :

Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Fast Quantitative Magnetic Resonance Imaging

Fast Quantitative Magnetic Resonance Imaging Book
Author : Guido Buonincontri,Joshua Kaggie,Martin Graves
Publisher : Morgan & Claypool Publishers
Release : 2020-02-20
ISBN : 1681736950
Language : En, Es, Fr & De

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Book Description :

Among medical imaging modalities, magnetic resonance imaging (MRI) stands out for its excellent soft-tissue contrast, anatomical detail, and high sensitivity for disease detection. However, as proven by the continuous and vast effort to develop new MRI techniques, limitations and open challenges remain. The primary source of contrast in MRI images are the various relaxation parameters associated with the nuclear magnetic resonance (NMR) phenomena upon which MRI is based. Although it is possible to quantify these relaxation parameters (qMRI) they are rarely used in the clinic, and radiological interpretation of images is primarily based upon images that are relaxation time weighted. The clinical adoption of qMRI is mainly limited by the long acquisition times required to quantify each relaxation parameter as well as questions around their accuracy and reliability. More specifically, the main limitations of qMRI methods have been the difficulty in dealing with the high inter-parameter correlations and a high sensitivity to MRI system imperfections. Recently, new methods for rapid qMRI have been proposed. The multi-parametric models at the heart of these techniques have the main advantage of accounting for the correlations between the parameters of interest as well as system imperfections. This holistic view on the MR signal makes it possible to regress many individual parameters at once, potentially with a higher accuracy. Novel, accurate techniques promise a fast estimation of relevant MRI quantities, including but not limited to longitudinal (T1) and transverse (T2) relaxation times. Among these emerging methods, MR Fingerprinting (MRF), synthetic MR (syMRI or MAGIC), and T1‒T2 Shuffling are making their way into the clinical world at a very fast pace. However, the main underlying assumptions and algorithms used are sometimes different from those found in the conventional MRI literature, and can be elusive at times. In this book, we take the opportunity to study and describe the main assumptions, theoretical background, and methods that are the basis of these emerging techniques. Quantitative transient state imaging provides an incredible, transformative opportunity for MRI. There is huge potential to further extend the physics, in conjunction with the underlying physiology, toward a better theoretical description of the underlying models, their application, and evaluation to improve the assessment of disease and treatment efficacy.

Quantitative MRI in Cancer

Quantitative MRI in Cancer Book
Author : Thomas E. Yankeelov,David R. Pickens,Ronald R. Price
Publisher : Taylor & Francis
Release : 2011-09-13
ISBN : 1439820589
Language : En, Es, Fr & De

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Book Description :

Propelling quantitative MRI techniques from bench to bedside, Quantitative MRI in Cancer presents a range of quantitative MRI methods for assessing tumor biology. It includes biophysical and theoretical explanations of the most relevant MRI techniques as well as examples of these techniques in cancer applications. The introductory part of the book covers basic cancer biology, theoretical aspects of NMR/MRI physics, and the hardware required to form MR images. Forming the core of the book, the next three parts illustrate how to characterize tissue properties with endogenous and exogenous contrast mechanisms and discuss common image processing techniques relevant for cancer. The final part explores emerging areas of MR cancer characterization, including radiation therapy planning, cellular and molecular imaging, pH imaging, and hyperpolarized MR. Each of the post-introductory chapters describes the salient qualitative and quantitative aspects of the techniques before proceeding to preclinical and clinical applications. Each chapter also contains references for further study. Leading the way toward more personalized medicine, this text brings together existing and emerging quantitative MRI techniques for assessing cancer. It provides a self-contained overview of the theoretical and experimental essentials and state of the art in cancer MRI.

Quantitative Magnetic Resonance Imaging and Spectroscopy of Vertebral Bone Marrow Addressing Confounding Effects in the Measurement of Fat Fraction and Apparent Diffusion Coefficient

Quantitative Magnetic Resonance Imaging and Spectroscopy of Vertebral Bone Marrow  Addressing Confounding Effects in the Measurement of Fat Fraction and Apparent Diffusion Coefficient Book
Author : Michael Dieckmeyer
Publisher : Unknown
Release : 2019
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Quantitative Magnetic Resonance Imaging and Spectroscopy of Vertebral Bone Marrow Addressing Confounding Effects in the Measurement of Fat Fraction and Apparent Diffusion Coefficient book written by Michael Dieckmeyer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Quantitative Magnetic Resonance Imaging of Ultrasound Acoustic Fields

Quantitative Magnetic Resonance Imaging of Ultrasound Acoustic Fields Book
Author : Conrad Leigh Walker
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Quantitative Magnetic Resonance Imaging of Ultrasound Acoustic Fields book written by Conrad Leigh Walker, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Quantitative Magnetic Resonance Imaging Biomarkers for Diffuse Liver Disease Technical Development and Validation

Quantitative Magnetic Resonance Imaging Biomarkers for Diffuse Liver Disease  Technical Development and Validation Book
Author : Xiaoke Wang
Publisher : Unknown
Release : 2019
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Non-alcoholic fatty liver disease (NAFLD) is a common liver disorder hallmarked by abnormal deposition of fat, i.e.: hepatic steatosis. NAFLD can take the form of non-alcoholic steatohepatitis (NASH) or isolated steatosis. Both forms of NAFLD can cause chronic liver injuries which leads to the progression into liver fibrosis. At the same time, NAFLD is a known risk factor of type-II diabetes and premature cardiovascular diseases. Although liver fibrosis is less common than NAFLD, it has serious complications such as liver failure. Cirrhosis as a form of advanced fibrosis is a risk factor of hepatocellular carcinoma. Effective treatments are emerging for NAFLD and liver fibrosis. Lifestyle intervention has been demonstrated to reduce hepatic steatosis and inflammation. In the case of viral hepatitis, treatment for hepatitis C virus infection often leads to the reversal of liver fibrosis (even in patients with cirrhosis). The accurate evaluation of hepatic steatosis and fibrosis using non-invasive magnetic resonance imaging (MRI) methods are needed to improve the diagnosis and treatment monitoring of patients afflicted by these conditions. Chemical shift encoded (CSE)-MRI has been established as a quantitative imaging biomarker (QIB) for hepatic steatosis. In this dissertation, the effect of non-standardized spectral model of fat was evaluated such that meaningful comparisons can be made between results obtained at different research and clinical sites. A T[subscript 1]-corrected variable flip angle (VFA) CSE-MRI was also proposed and rigorously evaluated for fat quantification in the hope of improving the precision of CSE-MRI fat quantification. Quantitative diffusion MRI using an intra-voxel incoherent motion (IVIM) model and T[subscript 2] mapping have shown promise for the evaluation of liver fibrosis. However, some additional development and validation is required for them to be recognized as QIBs. In this dissertation, a novel acetone-based diffusion phantom was proposed to provide a controlled environment for the development of quantitative diffusion MRI techniques. Further, to enable the quantification of T[subscript 2] from the water signal (parenchyma) and simultaneous quantification of R[subscript 2]*, a novel phase-based T[subscript 2] mapping technique was developed with its feasibility in the liver demonstrated.

Quantitative MRI of the Spinal Cord

Quantitative MRI of the Spinal Cord Book
Author : Julien Cohen-Adad,Claudia Wheeler-Kingshott
Publisher : Academic Press
Release : 2014-01-16
ISBN : 0123972825
Language : En, Es, Fr & De

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Book Description :

Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory’s applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord. Chapters authored by international experts in the field of MRI of the spinal cord Contains “cooking recipes —examples of imaging parameters for each quantitative technique—designed to aid researchers and clinicians in using them in practice Ideal for clinical settings

The Parietal Lobe and Schizophrenia

The Parietal Lobe and Schizophrenia Book
Author : Robert Matthew Donnino
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Parietal Lobe and Schizophrenia book written by Robert Matthew Donnino, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Quantitative Magnetic Resonance Measurements of Porous Media

Quantitative Magnetic Resonance Measurements of Porous Media Book
Author : Sarah Vashaee
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"Magnetic resonance imaging (MRI) is a powerful tool for the non-destructive measurement of fluid content and fluid behavior in porous media. The essential factor in quantitative MRI of such systems is a reliable measure of fluid quantity in the pore space. Quantitative imaging is impaired in many cases by non-uniform B1 fields in the sample space. In this thesis a novel method is described for mapping B1 inhomogeneities based on measurement of the B1 field employing centric-scan pure phase encode MRI measurements. The resultant B1 map is employed to correct B1 related non-uniformities in MR profiles, which leads to quantitative density profiling. The new B1 mapping technique is also employed to investigate B1 induced MRI artifacts by analyzing image distortions surrounding two geometrically identical metallic strips of aluminum and lead. Quantitative density profiles may be acquired in porous media with a spatially selective adiabatic inversion pulse, which is immune to B1 field non-uniformities. The pulse is applied in the presence of a slice selective magnetic field gradient to restrict the field of view to a region of interest in which the B1 field is fairly uniform. This is advantageous in axial profiling of petroleum reservoir core samples and core plugs in which the sample of interest may be much longer than the natural field of view defined by the RF probe and region of constant magnetic field gradient. The adiabatic slice selection lends itself to a spatially selective T2 distribution measurement when a CPMG pulse sequence follows the slice selection. This method is an alternative to MRI-based techniques for T2 mapping in porous media when T2 is required to be measured at only a few positions along the sample, and a resolution of 5 mm is acceptable. The above T2 distribution mapping method is compared with spin-echo SPI (SESPI) and DANTE-Z CPMG methods in terms of spatial resolution, minimum observable T2 and sensitivity. Finally, multi-slice T2 measurement employing the longitudinal Hadamard encoding technique and adiabatic inversion pulses is discussed. The method has an inherent sensitivity advantage over corresponding slice-by-slice local T2 measurements."--Pages ii-iii.

Quantitative MRI of the Brain

Quantitative MRI of the Brain Book
Author : Paul Tofts
Publisher : John Wiley & Sons
Release : 2005-08-19
ISBN : 0470869496
Language : En, Es, Fr & De

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Book Description :

2004 BMA Medical Book Competition Winner (Radiology category) “This is an exciting book, with a new approach to use of the MRI scanner. It bridges the gap between clinical research and general neuro-radiological practice. It is accessible to the clinical radiologist, and yet thorough in its treatment of the underlying physics and of the science of measurement. It is likely to become a classic.” British Medical Association This indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. It contains both the methodology and clinical applications, reflecting the increasing interest in quantitative MR in studying disease and its progression. The editor is an MR scientist with an international reputation for high quality research The contributions are written jointly by MR physicists and MR clinicians, producing a practical book for both the research and medical communities A practical book for both the research and medical communities “Paul Tofts has succeeded brilliantly in capturing the essence of what needs to become the future of radiology in particular, and medicine in general – quantitative measurements of disease.” Robert I. Grossman, M.D. New York, University School of Medicine (from the Foreword)

Quantitative MRI Morphology of Invasive Breast Cancer Correlation with Immunohistochemical Biomarkers and Subtypes

Quantitative MRI Morphology of Invasive Breast Cancer  Correlation with Immunohistochemical Biomarkers and Subtypes Book
Author : Anonim
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Background: Breast cancer is a heterogeneous disease with intrinsic molecular subtypes. The different biology and histology of breast cancer exhibit different tumor morphology at breast magnetic resonance imaging (MRI). However, few studies have examined the quantitative relationship between the MRI morphological and immunohistochemical features in breast cancer. Purpose: To investigate the correlations between tumor roundness, as quantitatively assessed with MRI and biomarkers or subtypes of breast cancer. Material and Methods: A total of 280 women (mean age, 51 years; range, 28–79 years) with 282 invasive breast cancers (

MRI of the Knee An Issue of Magnetic Resonance Imaging Clinics of North America E Book

MRI of the Knee  An Issue of Magnetic Resonance Imaging Clinics of North America  E Book Book
Author : Kirkland W. Davis
Publisher : Elsevier Health Sciences
Release : 2014-11-13
ISBN : 0323323804
Language : En, Es, Fr & De

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Book Description :

This issue, edited by Dr. Kirkland Davis, will comprehensively review imaging of the knee. Articles will include: Magnetic Resonance Imaging of the Meniscus; MRI of Cruciate Ligaments; Magnetic Resonance Imaging of the Extensor Mechanism; Quantitative Magnetic Resonance Imaging of the Articular Cartilage of the Knee Joint; Magnetic Resonance Imaging of the Pediatric Knee; MRI of Extra-Synovial Inflammation and Impingement about the Knee; A Biomechanical Approach to Interpreting MRI of Knee Injuries; MRI Assessment of Arthritis of the Knee; MRI of the Post-Operative Meniscus; MR Imaging of Cartilage Repair Procedures; Imaging the Knee in the Setting of Metal Hardware, and more!

Quantitative Dynamic Contrast enhanced Magnetic Resonance Imaging of the Breast

Quantitative Dynamic Contrast enhanced Magnetic Resonance Imaging of the Breast Book
Author : Greg O. Cron
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Quantitative Dynamic Contrast enhanced Magnetic Resonance Imaging of the Breast book written by Greg O. Cron, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Magnetic Resonance in Food Science

Magnetic Resonance in Food Science Book
Author : Francesco Capozzi,Luca Laghi,Peter S. Belton
Publisher : Royal Society of Chemistry
Release : 2015-04-16
ISBN : 1782620311
Language : En, Es, Fr & De

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Book Description :

Magnetic Resonance has become an established technique to improve the understanding of food systems. Capturing contributions from a whole range of applications in food and representing the latest technical innovations, this will be a contemporary book on the topic. Based on a conference which has established an international reputation as the forum for advances in applications of magnetic resonance to food, the coverage will be dedicated to multiscale definition of food, quantitative NMR (qNMR), foodomics, on-line non-invasive NMR (dedicated to Brian P. Hills), quality and safety and new developments in the area. It is aimed at academics and industrialists who are committed to the utilisation of MR tools to improve our understanding of food.