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Pyridines From Lab To Production

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Pyridines from lab to production

Pyridines  from lab to production Book
Author : Eric F.V. Scriven
Publisher : Academic Press
Release : 2013-01-08
ISBN : 0123852366
Language : En, Es, Fr & De

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Book Description :

Provides a synthetic armory of tools to aid the practicing chemist by reviewing the most reliable historical methods alongside new methods/ Written by scientists who have actually used these in synthesis. By emphasizing tricks and tips to optimize reactions for the best yields and purity, which are often missing from the primary literature, this book provides another dimension for the synthetic chemist. A combined academic and industrial approach evaluates the best methods for different scales of reaction and discusses practical tips (e.g. when to stop a reaction early to maximize purity or when to re-use side products). Chapters also assess whether to make or source starting materials, how to connect them and what are the best synthetic routes. The book is designed to be a stand-alone reference, but also provides cross references to leading reviews and the Comprehensive Heterocyclic Chemistry reference works for those who want to learn more. Reviews tried and tested practical methods to help the reader select the best method for their research Includes tips, tricks and hints to enable the reader to get the best yield or cleanest product out of their reaction for synthesising or transforming a pyridine derivative Written by both academic researchers and industry leaders this provides a unique view of how to get the most out of a reaction no matter what scale you are running this on

Asymmetric Dearomatization Reactions

Asymmetric Dearomatization Reactions Book
Author : Shu-Li You
Publisher : John Wiley & Sons
Release : 2016-06-03
ISBN : 3527698469
Language : En, Es, Fr & De

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Book Description :

The first comprehensive account of the rapidly growing field of asymmetric dearomatization reactions with a focus on catalytic methods. It introduces the concept of dearomatization and describes recent progress in asymmetric reaction procedures with different catalyst systems, such as organocatalysts, transition metal catalysts, and enzymes. Chapters on dearomatizations of electron-deficient aromatic rings, dearomatization reactions via transition metal-catalyzed cross-couplings as well as dearomatization strategies in the synthesis of complex natural products are also included. Written by pioneers in the field, this is a highly valuable source of information not only for professional synthetic chemists in academia and industry but also for all those are interested in asymmetric methodologies and organic synthesis in general.

Best Synthetic Methods

Best Synthetic Methods Book
Author : Chris Timperley
Publisher : Newnes
Release : 2014-12-01
ISBN : 0080982247
Language : En, Es, Fr & De

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Book Description :

Best Synthetic Methods: Organophosphorus (V) Chemistry provides systematic coverage of the most common classes of pentavalent organophosphorus compounds and reagents (including phosphonyl, phosphoryl, and organophosphates), and allows researchers an easy point of entry into this complex and economically important field. The book follows the Best Synthetic Methods format, containing practical methods, synthetic tips, and shortcuts. Where relevant, articles include toxicity data and historical context for the reactions. Typical analytical and spectroscopic data are also presented to enable scientists to identify key compound characteristics. The book is a valuable companion to research chemists in both academia and industry, summarizing the best practical methods (often originating in difficult-to-access, foreign-language primary literature) in one place. It is ideally suited for those working on industrial applications of these compounds, including insecticides, herbicides, flame retardants, and plasticizers. Includes a mixture of tried and tested, historical methods that are proven to work, alongside new methods to provide scientists with a quick, time-saving resource of reliable methods Includes tips and tricks to get reactions to work; important information often missing from other sources Includes key analytical data for compounds, so scientists have one handy resource to select, perform, and analyze the best reaction

Synthetic Methods in Drug Discovery

Synthetic Methods in Drug Discovery Book
Author : David C. Blakemore,Paul M. Doyle,Yvette M. Fobian
Publisher : Royal Society of Chemistry
Release : 2016-05-30
ISBN : 1849738033
Language : En, Es, Fr & De

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Book Description :

The number of available synthetic methods can be overwhelming. In order to create novel motifs and templates which confer new and potentially valuable drug-like properties, it is important to know which synthetic methodologies will give the best results. Similarly, which methodologies are used to progress potential drug candidates from leads through the development process? What are the current industrial research problems and how can they be resolved in an industrial setting? This book highlights key methods that have real impact in drug discovery and facilitate delivery of drug molecules. Synthetic Methods in Drug Discovery Volume 1 focuses on the hugely important area of transition metal mediated methods used in industry. Current methods of importance such as the Suzuki-Miyaura coupling, Buchwald-Hartwig couplings and CH activation are discussed. In addition, exciting emerging areas such as decarboxylative coupling, and the uses of iron and nickel in coupling reactions are also covered. This book provides both academic and industrial perspectives on some key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Edited and authored by leading scientists from both academia and industry, this book will be a valuable reference for all chemists involved in drug discovery as well as postgraduate students in medicinal chemistry.

Flow and Microreactor Technology in Medicinal Chemistry

Flow and Microreactor Technology in Medicinal Chemistry Book
Author : Esther Alza
Publisher : John Wiley & Sons
Release : 2022-06-13
ISBN : 3527824618
Language : En, Es, Fr & De

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Book Description :

Learn to master a powerful technology to enable a faster drug discovery workflow The ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled automated syntheses that rely on miniature flow reactors—with integrated analysis of the resulting products—provide a workable technology for synthesizing new chemical substances very quickly and with minimal effort. In Flow and Microreactor Technology in Medicinal Chemistry, early adopters of this ground-breaking technology describe its current and potential uses in medicinal chemistry. Based on successful examples of the use of flow and microreactor synthesis for drug-like compounds, the book introduces current as well as emerging uses for automated synthesis in a drug discovery context. Flow and Microreactor Technology in Medicinal Chemistry readers will also find: Numerous case studies that address the most common applications of this technology in the day-to-day work of medicinal chemists How to integrate flow synthesis with drug discovery How to perform enantioselective reactions under continuous flow conditions Flow and Microreactor Technology in Medicinal Chemistry is a valuable practical reference for medicinal chemists, organic chemists, and natural products chemists, whether they are working in academia or in the pharmaceutical industry.

U S Government Research Reports

U S  Government Research Reports Book
Author : Anonim
Publisher : Unknown
Release : 1962
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download U S Government Research Reports book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease Book
Author : Anonim
Publisher : U.S. Government Printing Office
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Organophosphorus Chemistry

Organophosphorus Chemistry Book
Author : David W Allen,David Loakes,John C Tebby
Publisher : Royal Society of Chemistry
Release : 2019-04-10
ISBN : 1788014995
Language : En, Es, Fr & De

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Book Description :

This annual review of the literature presents a comprehensive and critical survey of the vast field of study involving organophosphorus compounds, from phosphines and related P-C bonded compounds to phosphorus acids, phosphine chalcogenides and nucleotides. The Editors have added to the content with a timely chapter on the recent developments in green synthetic approaches in organophosphorus chemistry to reflect current interests in the area. With an emphasis on interdisciplinary content, this book is aimed at the worldwide organic chemistry and engineering research communities.

Ignition

Ignition  Book
Author : John Drury Clark
Publisher : Rutgers University Press
Release : 2018-05-23
ISBN : 0813599199
Language : En, Es, Fr & De

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Book Description :

This newly reissued debut book in the Rutgers University Press Classics Imprint is the story of the search for a rocket propellant which could be trusted to take man into space. This search was a hazardous enterprise carried out by rival labs who worked against the known laws of nature, with no guarantee of success or safety. Acclaimed scientist and sci-fi author John Drury Clark writes with irreverent and eyewitness immediacy about the development of the explosive fuels strong enough to negate the relentless restraints of gravity. The resulting volume is as much a memoir as a work of history, sharing a behind-the-scenes view of an enterprise which eventually took men to the moon, missiles to the planets, and satellites to outer space. A classic work in the history of science, and described as “a good book on rocket stuff…that’s a really fun one” by SpaceX founder Elon Musk, readers will want to get their hands on this influential classic, available for the first time in decades.

Clinical Environmental Health and Toxic Exposures

Clinical Environmental Health and Toxic Exposures Book
Author : John Burke Sullivan,Gary R. Krieger
Publisher : Lippincott Williams & Wilkins
Release : 2001
ISBN : 9780683080278
Language : En, Es, Fr & De

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Book Description :

Now in its revised and updated Second Edition, this volume is the most comprehensive and authoritative text in the rapidly evolving field of environmental toxicology. The book provides the objective information that health professionals need to prevent environmental health problems, plan for emergencies, and evaluate toxic exposures in patients.Coverage includes safety, regulatory, and legal issues; clinical toxicology of specific organ systems; emergency medical response to hazardous materials releases; and hazards of specific industries and locations. Nearly half of the book examines all known toxins and environmental health hazards. A Brandon-Hill recommended title.

Scientific and Technical Aerospace Reports

Scientific and Technical Aerospace Reports Book
Author : Anonim
Publisher : Unknown
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Scientific and Technical Aerospace Reports book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Alkaloids

Alkaloids Book
Author : Joanna Kurek
Publisher : BoD – Books on Demand
Release : 2019-11-13
ISBN : 1789845769
Language : En, Es, Fr & De

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Book Description :

"Alkaloids" is intended for by chemistry, biochemistry, pharmacy, and other medical students, biologists, chemists, biochemists, and other professionals involved in the field of alkaloids. All chapters in this book are written by professionals in the areas of alkaloid chemistry, biology, pharmacy, and other interesting applications. The chapters cover interesting and less obvious information about different groups of alkaloids.

Chemical Week

Chemical Week Book
Author : Anonim
Publisher : Unknown
Release : 1952
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Some vols. include Buyer's guide.

A text book of practical organic chemistry

A text book of practical organic chemistry Book
Author : Arthur I. Vogel
Publisher : Unknown
Release : 1972
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download A text book of practical organic chemistry book written by Arthur I. Vogel, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chemistry for Pharmacy Students

Chemistry for Pharmacy Students Book
Author : Professor Satyajit D. Sarker,Lutfun Nahar
Publisher : John Wiley & Sons
Release : 2013-05-28
ISBN : 1118687531
Language : En, Es, Fr & De

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Book Description :

"This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student... the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read." –Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life, with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry required for all pharmacy degree courses student-friendly and written at a level suitable for non-chemistry students includes learning objectives at the beginning of each chapter focuses on the physical properties and actions of drug molecules

Technical Abstract Bulletin

Technical Abstract Bulletin Book
Author : Defense Documentation Center (U.S.)
Publisher : Unknown
Release : 1961-10
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Technical Abstract Bulletin book written by Defense Documentation Center (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nitro Compounds and Their Derivatives in Organic Synthesis

Nitro Compounds and Their Derivatives in Organic Synthesis Book
Author : Nagatoshi Nishiwaki
Publisher : Unknown
Release : 2020-09-16
ISBN : 9783039431489
Language : En, Es, Fr & De

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Book Description :

Nitro chemistry plays an important role in organic synthesis to construct new frameworks. This is due to the diverse properties of the nitro group. The strong electron-withdrawing ability of the nitro group reduces the electron density of the scaffold, facilitating reactions with nucleophiles or electron transfer. In addition, the -hydrogen of the nitro group is highly acidic, giving a stable anion, which facilitates reactions with both electrophilic and nucleophilic reagents. In addition, the nitro group also serves as a good leaving group, which facilitates transformation to a wide variety of functional groups. Despite the substantial contributions of many researchers, nitro chemistry is still an exciting and challenging research area. This book brings together recent original research and review articles contributed by an international team of leading experts and pioneers in organic synthesis using nitro groups. It is sure to provide useful information and promising insights for researchers.

Target Sites of Herbicide Action

Target Sites of Herbicide Action Book
Author : Peter Boger,Gerhard Sandmann
Publisher : CRC Press
Release : 2020-11-25
ISBN : 1000103110
Language : En, Es, Fr & De

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Book Description :

This publication is based on the plant processes and reaction sites for which reliable knowledge on both their physiology and biochem-istry and the mode of herbicidal action is available. Targets of the agrochemical research, such as enzymes of biosynthetic pathways or herbicide-binding peptides in the photosynthetic membrane, are highlighted. Detailed knowledge about the target sites will allow bio-chemical model systems to evaluate the biological activity of newly synthesized compounds before their conventional screening in the greenhouse. Quantitative structure/activity relationships should be performed more reliably with simple biological species or enzymol-ogy assays, to aid in the rational design of pesticides. This text is highly valuable for plant physiologists, pathologists, and chemists in the agrochemical industry and universities.

Selected Water Resources Abstracts

Selected Water Resources Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Selected Water Resources Abstracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Energy Research Abstracts

Energy Research Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 1994-11
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Energy Research Abstracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.