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Protein Physics

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Protein Physics

Protein Physics Book
Author : Alexei V. Finkelstein,Oleg Ptitsyn
Publisher : Elsevier
Release : 2016-06-22
ISBN : 0081012365
Language : En, Es, Fr & De

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Book Description :

Protein Physics: A Course of Lectures covers the most general problems of protein structure, folding and function. It describes key experimental facts and introduces concepts and theories, dealing with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states. The book systematically summarizes and presents the results of several decades of worldwide fundamental research on protein physics, structure, and folding, describing many physical models that help readers make estimates and predictions of physical processes that occur in proteins. New to this revised edition is the inclusion of novel information on amyloid aggregation, natively disordered proteins, protein folding in vivo, protein motors, misfolding, chameleon proteins, advances in protein engineering & design, and advances in the modeling of protein folding. Further, the book provides problems with solutions, many new and updated references, and physical and mathematical appendices. In addition, new figures (including stereo drawings, with a special appendix showing how to use them) are added, making this an ideal resource for graduate and advanced undergraduate students and researchers in academia in the fields of biophysics, physics, biochemistry, biologists, biotechnology, and chemistry. Fully revised and expanded new edition based on the latest research developments in protein physics Written by the world's top expert in the field Deals with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states Summarizes, in a systematic form, the results of several decades of worldwide fundamental research on protein physics and their structure and folding Examines experimental data on protein structure in the post-genome era

Protein Physics

Protein Physics Book
Author : Alexei V. Finkelstein,Oleg Borisovich Ptit︠s︡yn
Publisher : Academic Press
Release : 2002-05-14
ISBN : 9780122567810
Language : En, Es, Fr & De

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Book Description :

"Covers the most general problems of protein structure, folding and function and introduces the concepts and theories. It deals with fibrous, membrane and especially water-soluble globular proteins, in both their native and denatured states. The book summarizes and presents in a systematic way the results of several decades of worldwide fundamental research on protein physics, structure and folding"--Back cover.

The Physics of Proteins

The Physics of Proteins Book
Author : Hans Frauenfelder
Publisher : Springer Science & Business Media
Release : 2010-05-30
ISBN : 1441910441
Language : En, Es, Fr & De

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Book Description :

Provides an introduction to the structure and function of biomolecules --- especially proteins --- and the physical tools used to investigate them The discussion concentrates on physical tools and properties, emphasizing techniques that are contributing to new developments and avoiding those that are already well established and whose results have already been exploited fully New tools appear regularly - synchrotron radiation, proton radiology, holography, optical tweezers, and muon radiography, for example, have all been used to open new areas of understanding

Monte Carlo Methods in Chemical Physics

Monte Carlo Methods in Chemical Physics Book
Author : David M. Ferguson,J. Ilja Siepmann,Donald G. Truhlar
Publisher : John Wiley & Sons
Release : 2009-09-09
ISBN : 0470142170
Language : En, Es, Fr & De

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Book Description :

In Monte Carlo Methods in Chemical Physics: An Introduction to the Monte Carlo Method for Particle Simulations J. Ilja Siepmann Random Number Generators for Parallel Applications Ashok Srinivasan, David M. Ceperley and Michael Mascagni Between Classical and Quantum Monte Carlo Methods: "Variational" QMC Dario Bressanini and Peter J. Reynolds Monte Carlo Eigenvalue Methods in Quantum Mechanics and Statistical Mechanics M. P. Nightingale and C.J. Umrigar Adaptive Path-Integral Monte Carlo Methods for Accurate Computation of Molecular Thermodynamic Properties Robert Q. Topper Monte Carlo Sampling for Classical Trajectory Simulations Gilles H. Peslherbe Haobin Wang and William L. Hase Monte Carlo Approaches to the Protein Folding Problem Jeffrey Skolnick and Andrzej Kolinski Entropy Sampling Monte Carlo for Polypeptides and Proteins Harold A. Scheraga and Minh-Hong Hao Macrostate Dissection of Thermodynamic Monte Carlo Integrals Bruce W. Church, Alex Ulitsky, and David Shalloway Simulated Annealing-Optimal Histogram Methods David M. Ferguson and David G. Garrett Monte Carlo Methods for Polymeric Systems Juan J. de Pablo and Fernando A. Escobedo Thermodynamic-Scaling Methods in Monte Carlo and Their Application to Phase Equilibria John Valleau Semigrand Canonical Monte Carlo Simulation: Integration Along Coexistence Lines David A. Kofke Monte Carlo Methods for Simulating Phase Equilibria of Complex Fluids J. Ilja Siepmann Reactive Canonical Monte Carlo J. Karl Johnson New Monte Carlo Algorithms for Classical Spin Systems G. T. Barkema and M.E.J. Newman

Soft Condensed Matter Physics in Molecular and Cell Biology

Soft Condensed Matter Physics in Molecular and Cell Biology Book
Author : W.C.K. Poon,David Andelman
Publisher : CRC Press
Release : 2006-01-13
ISBN : 142000333X
Language : En, Es, Fr & De

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Book Description :

Soft condensed matter physics, which emerged as a distinct branch of physics in the 1990s, studies complex fluids: liquids in which structures with length scale between the molecular and the macroscopic exist. Polymers, liquid crystals, surfactant solutions, and colloids fall into this category. Physicists deal with properties of soft matter system

Lectures on Statistical Physics and Protein Folding

Lectures on Statistical Physics and Protein Folding Book
Author : Kerson Huang
Publisher : World Scientific
Release : 2005-05-30
ISBN : 9814481068
Language : En, Es, Fr & De

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Book Description :

' This book introduces an approach to protein folding from the point of view of kinetic theory. There is an abundance of data on protein folding, but few proposals are available on the mechanism driving the process. Here, presented for the first time, are suggestions on possible research directions, as developed by the author in collaboration with C C Lin. The first half of this invaluable book contains a concise but relatively complete review of relevant topics in statistical mechanics and kinetic theory. It includes standard topics such as thermodynamics, the Maxwell-Boltzmann distribution, and ensemble theory. Special discussions include the dynamics of phase transitions, and Brownian motion as an illustration of stochastic processes. The second half develops topics in molecular biology and protein structure, with a view to discovering mechanisms underlying protein folding. Attention is focused on the energy flow through the protein in its folded state. A mathematical model, based on the Brownian motion of coupled harmonic oscillators, is worked out in the appendix. Contents:EntropyMaxwell–Boltzmann DistributionFree EnergyChemical PotentialPhase TransitionsKinetics of Phase TransitionsThe Order ParameterCorrelation FunctionStochastic ProcessesLangevin EquationThe Life ProcessSelf-AssemblyKinetics of Protein FoldingPower Laws in Protein FoldingSelf-Avoiding Walk and TurbulenceConvergent Evolution in Protein Folding Readership: Graduate students, researchers and academics interested in statistical physics and molecular biology. Keywords:Statistical Physics;Protein Folding;BiophysicsReviews:“My particularly favorite is the chapter on order parameters, explaining with simplicity and clarity this subject so frequently difficult and confusing for the beginning students … the book makes a strong attempt to place the protein folding problem where it really belongs — in the context of fundamental statistical mechanics. Whether the attempt is successful or not is a matter of a reader's opinion, but the very direction is both timely and welcome.”Professor Alexander Grosberg University of Minnesota '

Physics of Charged Macromolecules

Physics of Charged Macromolecules Book
Author : Murugappan Muthukumar
Publisher : Cambridge University Press
Release : 2023-02-28
ISBN : 0521864879
Language : En, Es, Fr & De

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Book Description :

A clear and intuitive introduction to the physics of charged macromolecules, from fundamentals to the latest research developments.

From Protein Structure to Function with Bioinformatics

From Protein Structure to Function with Bioinformatics Book
Author : Daniel John Rigden
Publisher : Springer Science & Business Media
Release : 2008-12-11
ISBN : 1402090587
Language : En, Es, Fr & De

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Book Description :

Proteins lie at the heart of almost all biological processes and have an incredibly wide range of activities. Central to the function of all proteins is their ability to adopt, stably or sometimes transiently, structures that allow for interaction with other molecules. An understanding of the structure of a protein can therefore lead us to a much improved picture of its molecular function. This realisation has been a prime motivation of recent Structural Genomics projects, involving large-scale experimental determination of protein structures, often those of proteins about which little is known of function. These initiatives have, in turn, stimulated the massive development of novel methods for prediction of protein function from structure. Since model structures may also take advantage of new function prediction algorithms, the first part of the book deals with the various ways in which protein structures may be predicted or inferred, including specific treatment of membrane and intrinsically disordered proteins. A detailed consideration of current structure-based function prediction methodologies forms the second part of this book, which concludes with two chapters, focusing specifically on case studies, designed to illustrate the real-world application of these methods. With bang up-to-date texts from world experts, and abundant links to publicly available resources, this book will be invaluable to anyone who studies proteins and the endlessly fascinating relationship between their structure and function.

Protein Actions Principles and Modeling

Protein Actions  Principles and Modeling Book
Author : Ivet Bahar,Robert L. Jernigan,Ken A. Dill
Publisher : Garland Science
Release : 2017-02-14
ISBN : 1351815016
Language : En, Es, Fr & De

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Book Description :

Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.

Computational Methods for Protein Structure Prediction and Modeling

Computational Methods for Protein Structure Prediction and Modeling Book
Author : Ying Xu,Dong Xu,Jie Liang
Publisher : Springer Science & Business Media
Release : 2007-08-24
ISBN : 0387683720
Language : En, Es, Fr & De

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Book Description :

Volume One of this two-volume sequence focuses on the basic characterization of known protein structures, and structure prediction from protein sequence information. Eleven chapters survey of the field, covering key topics in modeling, force fields, classification, computational methods, and structure prediction. Each chapter is a self contained review covering definition of the problem and historical perspective; mathematical formulation; computational methods and algorithms; performance results; existing software; strengths, pitfalls, challenges, and future research.

Advances in Protein Chemistry

Advances in Protein Chemistry Book
Author : Anonim
Publisher : Academic Press
Release : 1980-01-23
ISBN : 0080582060
Language : En, Es, Fr & De

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Book Description :

Advances in Protein Chemistry

Proceedings of 8th European Chemistry Congress 2018

Proceedings of 8th European Chemistry Congress 2018 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2023-01-30
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

June 21-23, 2018 Paris, France Key Topics : Organic Chemistry, Inorganic Chemistry, Analytical Chemistry, Green Chemistry, Physical Chemistry, Theoretical Chemistry, Environmental Chemistry, Materials Chemistry, Medicinal Chemistry, Medical Biochemistry, Biological Chemistry, Nuclear Chemistry, Petro Chemicals, Multi-disciplinary Chemistry, Chemistry Education,

Geometry Driven Statistics

Geometry Driven Statistics Book
Author : Ian L. Dryden,John T. Kent
Publisher : John Wiley & Sons
Release : 2015-07-22
ISBN : 1118866614
Language : En, Es, Fr & De

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Book Description :

A timely collection of advanced, original material in the area of statistical methodology motivated by geometric problems, dedicated to the influential work of Kanti V. Mardia This volume celebrates Kanti V. Mardia's long and influential career in statistics. A common theme unifying much of Mardia’s work is the importance of geometry in statistics, and to highlight the areas emphasized in his research this book brings together 16 contributions from high-profile researchers in the field. Geometry Driven Statistics covers a wide range of application areas including directional data, shape analysis, spatial data, climate science, fingerprints, image analysis, computer vision and bioinformatics. The book will appeal to statisticians and others with an interest in data motivated by geometric considerations. Summarizing the state of the art, examining some new developments and presenting a vision for the future, Geometry Driven Statistics will enable the reader to broaden knowledge of important research areas in statistics and gain a new appreciation of the work and influence of Kanti V. Mardia.

Single Molecule Spectroscopy in Chemistry Physics and Biology

Single Molecule Spectroscopy in Chemistry  Physics and Biology Book
Author : Astrid Graslund
Publisher : Springer Science & Business Media
Release : 2010-04-17
ISBN : 3642025986
Language : En, Es, Fr & De

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Book Description :

Written by the leading experts in the field, this book describes the development and current state of the art in single molecule spectroscopy. The application of this technique, which started 1989, in physics, chemistry and biosciences is displayed.

Memorial Volume For Kerson Huang

Memorial Volume For Kerson Huang Book
Author : Hwee Boon Low,Kok Khoo Phua,Chi Xiong
Publisher : #N/A
Release : 2017-07-14
ISBN : 9813207442
Language : En, Es, Fr & De

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Book Description :

Professor Kerson Huang was a well respected theoretical physicist, who was also well versed in English and Chinese literature. He was born in Nanning, China, on 15 March 1928, and he was a fellow at the IAS, Princeton, from 1955-1957 before joining the faculty of MIT. He remained there until he retired from teaching in 1999. His research in theoretical physics included works on Bose-Einstein condensation and quantum field theory. In his long and illustrious career, Prof. Huang has worked with many prominent physicists. In 1957, he published a theory known as the hard-sphere model for Bose gases with Nobel Laureates Chen-Ning Yang and Tsung-Dao Lee. With Noble Laureate Steven Weinberg, he studied the ultimate temperature and the thermodynamics of early universe. While he was at Princeton, he also worked with atomic bomb developer J. Robert Oppenheimer. In recently years, Prof. Huang had been a visiting professor at Nanyang Technological University in Singapore, and worked on both biophysics and quantum cosmology.This memorial volume is dedicated to Prof. Huang who passed away peacefully at home on September 1, 2016 at the age of 88. The volume features the recollections of Prof. Huang by his former colleagues and students, including Profs Chen-Ning Yang and Samuel Ting, as well as their reflections on Prof. Huang's achievements in the various subdivisions of physics.

Molecular Modeling at the Atomic Scale

Molecular Modeling at the Atomic Scale Book
Author : Ruhong Zhou
Publisher : CRC Press
Release : 2014-08-21
ISBN : 1466562951
Language : En, Es, Fr & De

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Book Description :

Although molecular modeling has been around for a while, the groundbreaking advancement of massively parallel supercomputers and novel algorithms for parallelization is shaping this field into an exciting new area. Developments in molecular modeling from experimental and computational techniques have enabled a wide range of biological applications. Responding to this renaissance, Molecular Modeling at the Atomic Scale: Methods and Applications in Quantitative Biology includes discussions of advanced techniques of molecular modeling and the latest research advancements in biomolecular applications from leading experts. The book begins with a brief introduction of major methods and applications, then covers the development of cutting-edge methods/algorithms, new polarizable force fields, and massively parallel computing techniques, followed by descriptions of how these novel techniques can be applied in various research areas in molecular biology. It also examines the self-assembly of biomacromolecules, including protein folding, RNA folding, amyloid peptide aggregation, and membrane lipid bilayer formation. Additional topics highlight biomolecular interactions, including protein interactions with DNA/RNA, membrane, ligands, and nanoparticles. Discussion of emerging topics in biomolecular modeling such as DNA sequencing with solid-state nanopores and biological water under nanoconfinement round out the coverage. This timely summary contains the perspectives of leading experts on this transformation in molecular biology and includes state-of-the-art examples of how molecular modeling approaches are being applied to critical questions in modern quantitative biology. It pulls together the latest research and applications of molecular modeling and real-world expertise that can boost your research and development of applications in this rapidly changing field.

The Monte Carlo Approach To Biopolymers And Protein Folding

The Monte Carlo Approach To Biopolymers And Protein Folding Book
Author : Peter Grassberger,Walter Nadler,G T Barkema
Publisher : World Scientific
Release : 1998-11-06
ISBN : 9814544272
Language : En, Es, Fr & De

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Book Description :

Information on our detailed genetic code is increasing at a dramatic pace. We need to understand how that is translated into the three-dimensional structure of proteins in order to make use of the information. Progress in this field is hampered by the lack of precise force fields and of efficient codes for finding equilibrium configurations of heteropolymers. However, there has been rapid advance in recent years, and this volume discusses that.

Handbook of Porphyrin Science Volumes 16 20 With Applications to Chemistry Physics Materials Science Engineering Biology and Medicine

Handbook of Porphyrin Science  Volumes 16     20   With Applications to Chemistry  Physics  Materials Science  Engineering  Biology and Medicine Book
Author : Karl M Kadish,Kevin M Smith,Roger Guilard
Publisher : World Scientific
Release : 2012-06-08
ISBN : 9814462241
Language : En, Es, Fr & De

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Book Description :

This is the fourth set of Handbook of Porphyrin Science.Porphyrins, phthalocyanines and their numerous analogues and derivatives are materials of tremendous importance in chemistry, materials science, physics, biology and medicine. They are the red color in blood (heme) and the green in leaves (chlorophyll); they are also excellent ligands that can coordinate with almost every metal in the Periodic Table. Grounded in natural systems, porphyrins are incredibly versatile and can be modified in many ways; each new modification yields derivatives, demonstrating new chemistry, physics and biology, with a vast array of medicinal and technical applications.As porphyrins are currently employed as platforms for study of theoretical principles and applications in a wide variety of fields, the Handbook of Porphyrin Science represents a timely ongoing series dealing in detail with the synthesis, chemistry, physicochemical and medical properties and applications of polypyrrole macrocycles. Professors Karl Kadish, Kevin Smith and Roger Guilard are internationally recognized experts in the research field of porphyrins, each having his own separate area of expertise in the field. Between them, they have published over 1500 peer-reviewed papers and edited more than three dozen books on diverse topics of porphyrins and phthalocyanines. In assembling the new volumes of this unique handbook, they have selected and attracted the very best scientists in each sub-discipline as contributing authors.This handbook will prove to be a modern authoritative treatise on the subject as it is a collection of up-to-date works by world-renowned experts in the field. Complete with hundreds of figures, tables and structural formulas, and thousands of literature citations, all researchers and graduate students in this field will find the Handbook of Porphyrin Science an essential, major reference source for many years to come.

Protein Normal Modes

Protein Normal Modes Book
Author : William C. Reisdorf
Publisher : Unknown
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Protein Normal Modes book written by William C. Reisdorf, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.