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Protein Modificomics

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Protein Modificomics

Protein Modificomics Book
Author : Tanveer Ali Dar,Laishram Rajendrakumar Singh
Publisher : Academic Press
Release : 2019-05-18
ISBN : 0128119500
Language : En, Es, Fr & De

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Book Description :

Protein Modificomics: From Modifications to Clinical Perspectives comprehensively deals with all of the most recent aspects of post-translational modification (PTM) of proteins, including discussions on diseases involving PTMs, such as Alzheimer’s, Huntington’s, X-linked spinal muscular atrophy-2, aneurysmal bone cyst, angelman syndrome and OFC10. The book also discusses the role PTMs play in plant physiology and the production of medicinally important primary and secondary metabolites. The understanding of PTMs in plants helps us enhance the production of these metabolites without greatly altering the genome, providing robust eukaryotic systems for the production and isolation of desired products without considerable downstream and isolation processes. Provides thorough insights into the post translational modifications (PTMs) of proteins in both the plant and animal kingdom Presents diagrammatic representations of various protein modification and estimation mechanisms in four-color Includes coverage of diseases involving post translational modifications

Nitric Oxide in Plant Biology

Nitric Oxide in Plant Biology Book
Author : Vijay Pratap Singh,Samiksha Singh,Durgesh Kumar Tripathi,Maria C. Romero-Puertas,Luisa María Sandalio
Publisher : Academic Press
Release : 2021-09-19
ISBN : 0128187980
Language : En, Es, Fr & De

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Book Description :

Nitric Oxide in Plant Biology: An Ancient Molecule with Emerging Roles is an extensive volume which provides a broad and detailed overview of Nitric Oxide (NO) in plant biology. The book covers the entirety of the crucial role NO plays in the plant lifecycle, from the regulation of seed germination and growth to synthesis, nitrogen fixation and stress response. Beginning with NO production and NO homeostasis, Nitric Oxide in Plant Biology goes on to cover a variety of NO roles, with a focus on NO signalling, crosstalk and stress responses. Edited by leading experts in the field and featuring the latest research from laboratories from across the globe, it is a comprehensive resource of interest to students and researchers working in plant physiology, agriculture, biotechnology, and the pharmaceutical and food industries. Provides a broad and detailed overview on NO in plant biology, including NO production, NO signaling, NO homeostasis, crosstalk and stress responses Edited by leading experts in the field Features the latest research from laboratories from across the globe

Extracellular Matrix Omics

Extracellular Matrix Omics Book
Author : Sylvie Ricard-Blum
Publisher : Springer Nature
Release : 2021-09-26
ISBN : 3030583309
Language : En, Es, Fr & De

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Book Description :

Download Extracellular Matrix Omics book written by Sylvie Ricard-Blum, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Annual Plant Reviews Plant Proteomics

Annual Plant Reviews  Plant Proteomics Book
Author : Christine Finnie
Publisher : John Wiley & Sons
Release : 2008-04-15
ISBN : 1405173076
Language : En, Es, Fr & De

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Book Description :

The proteome comprises all protein species resulting from geneexpression in a cell, organelle, tissue or organism. By definition,proteomics aims to identify and characterise the expressionpattern, cellular location, activity, regulation,post-translational modifications, molecular interactions, threedimensional structures and functions of each protein in abiological system. In plant science, the number of proteome studies is rapidlyexpanding after the completion of the Arabidopsis thaliana genomesequence, and proteome analyses of other important or emergingmodel systems and crop plants are in progress or are beinginitiated. Proteome analysis in plants is subject to the sameobstacles and limitations as in other organisms, but the nature ofplant tissues, with their rigid cell walls and complex variety ofsecondary metabolites, means that extra challenges are involvedthat may not be faced when analysing other organisms. This volume aims to highlight the ways in which proteome analysishas been used to probe the complexities of plant biochemistry andphysiology. It is aimed at researchers in plant biochemistry,genomics, transcriptomics and metabolomics who wish to gain anup-to-date insight into plant proteomes, the information plantproteomics can yield and the directions plant proteome research istaking.

Protein Purification

Protein Purification Book
Author : Philip Bonner
Publisher : Taylor & Francis
Release : 2018-08-21
ISBN : 0429856962
Language : En, Es, Fr & De

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Book Description :

This second edition of Protein Purification provides a guide to the major chromatographic techniques, including non-affinity absorption techniques, affinity procedures, non-absorption techniques and methods for monitoring protein purity. The new edition of the book has been organized to encourage incremental learning about the topic, starting with the properties of water, progressing through the characteristics of amino acids and proteins which relate to the purification process. There is an overview of protein strategy and equipment, followed by discussions and examples of each technique and their applications. The basic theory and simple explanations given in Protein Purification make it an ideal handbook for final year undergraduates, and postgraduates, who are conducting research projects. It will also be a useful guide to more experienced researchers who need a good overview of the techniques and products used in protein purification. Key Features * Guide to the major techniques used in protein purification * Includes flowcharts to help the reader slect the best purification strategy * Contains step-by-step protocols that guide the reader through each technique and its use * Includes exercises and solutions

Signaling in the Heart

Signaling in the Heart Book
Author : José Marín-García
Publisher : Springer Science & Business Media
Release : 2011-06-21
ISBN : 9781441994615
Language : En, Es, Fr & De

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Book Description :

Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.

Drug Stability and Chemical Kinetics

Drug Stability and Chemical Kinetics Book
Author : Muhammad Sajid Hamid Akash,Kanwal Rehman
Publisher : Springer Nature
Release : 2020-11-01
ISBN : 9811564264
Language : En, Es, Fr & De

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Book Description :

This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics.

Mitochondria in Health and in Sickness

Mitochondria in Health and in Sickness Book
Author : Andrea Urbani,Mohan Babu
Publisher : Springer Nature
Release : 2019-08-26
ISBN : 9811383677
Language : En, Es, Fr & De

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Book Description :

Besides bringing together researchers and clinicians from various disciplines to share their scope of research on the seminal role of mitochondria in human disease, this original volume of the book has a broader appeal by exploring the health and disease of mitochondria, with specific emphasis on how mitochondrial dysfunction contributes to the development of various neurodegeneration, cancer, and metabolic disorders. The book also provides a foundational overview of the mitochondrial pathogenic or genetic variants and highlights various analytical tools used in the field of mitochondrial genetics; mitochondrial replacement therapy and strategies geared towards shifting heteroplasmy in individuals with mitochondrial disease; how state-of-the-art omics technologies (proteomics, functional genomics) have been employed to study mitochondrial biology in healthy and disease states; post-translational modifications in the regulation of mitochondrial proteins; and the role of mitochondria in host-pathogen interactions. Current approaches taken to study steady-state characteristics of mitochondrial structure and function in live mammalian cells in the contexts of normal and diseased states, and most recent research efforts to develop compounds with anti-cancer potential by targeting mitochondrial proteases or advances in therapeutic approaches towards mitochondrial disease were also explored. By covering this broad range of topics, our hope is to disseminate a wealth of knowledge on the critical role of mitochondria, and how to probe its function in health and in sickness.

The Glycome

The Glycome Book
Author : Adeel Malik,Tanveer A. Dar
Publisher : CRC Press
Release : 2021-07-08
ISBN : 1000344320
Language : En, Es, Fr & De

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Book Description :

This volume provides a comprehensive understanding of the enigmatic identity of the glycome, a complex but important area of research that has been largely ignored due to its complexity. The authors thoroughly deal with almost all aspects of the glycome, i.e., elucidation of the glycan identity enigma and its role in regulation of the cellular process, and in disease etiology. The book bridges the knowledge gap in understanding the glycome, from being a cell signature to its applications in disease etiology. In addition, it details many of the major insights regarding the possible role of the glycome in various diseases as a therapeutic marker. The book systematically covers the major aspects of the glycome, including the significance of substituting the diverse monosaccharide units to glycoproteins, the role of glycans in disease pathologies, and the challenges and advances in glycobiology. The authors stress the significance and huge encoding power of carbohydrates as well as provide helpful insights in framing the bigger picture. The Glycome: Understanding the Diversity and Complexity of Glycobiology details state-of-the-art developments and emerging challenges of glycome biology, which are going to be key areas of future research, not only in the glycobiology field but also in pharmaceutics.

Plant Proteomics

Plant Proteomics Book
Author : Jozef Samaj,Jay J. Thelen
Publisher : Springer Science & Business Media
Release : 2007-09-09
ISBN : 3540726179
Language : En, Es, Fr & De

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Book Description :

Plant Proteomics highlights rapid progress in this field, with emphasis on recent work in model plant species, sub-cellular organelles, and specific aspects of the plant life cycle such as signaling, reproduction and stress physiology. Several chapters present a detailed look at diverse integrated approaches, including advanced proteomic techniques combined with functional genomics, bioinformatics, metabolomics and molecular cell biology, making this book a valuable resource for a broad spectrum of readers.

Advances in Microalgae Biology and Sustainable Applications

Advances in Microalgae Biology and Sustainable Applications Book
Author : Flavia Vischi Winck,Diego Mauricio Riaño-Pachón,Telma Teixeira Franco
Publisher : Frontiers Media SA
Release : 2016-11-15
ISBN : 2889450147
Language : En, Es, Fr & De

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Book Description :

It has become more evident that many microalgae respond very differently than land plants to diverse stimuli. Therefore, we cannot reduce microalgae biology to what we have learned from land plants biology. However, we are still at the beginning of a comprehensive understanding of microalgae biology. Microalgae have been posited several times as prime candidates for the development of sustainable energy platforms, making thus the in-depth understanding of their biological features an important objective. Thus, the knowledge related to the basics of microalgae biology must be acquired and shared rapidly, fostering the development of potential applications. Microalgae biology has been studied for more than forty years now and more intensely since the 1970’s, when genetics and molecular biology approaches were integrated into the research programs. Recently, studies on the molecular physiology of microalgae have provided evidences on the particularities of these organisms, mainly in model species, such as Chlamydomonas reinhardtii. Of note, cellular responses in microalgae produce very interesting phenotypes, such as high lipid content in nitrogen deprived cells, increased protein content in cells under high CO2 concentrations, the modification of flagella structure and motility in basal body mutant strains, the different ancient proteins that microalgae uses to dissipate the harmful excess of light energy, the hydrogen production in cells under sulfur deprivation, to mention just a few. Moreover, several research groups are using high-throughput and data-driven technologies, including “omics” approaches to investigate microalgae cellular responses at a system-wide level, revealing new features of microalgae biology, highlighting differences between microalgae and land plants. It has been amazing to observe the efforts towards the development and optimization of new technologies required for the proper study of microalgae, including methods that opened new paths to the investigation of important processes such as regulatory mechanisms, signaling crosstalk, chemotactic mechanisms, light responses, chloroplast controlled mechanisms, among others. This is an exciting moment in microalgae research when novel data are been produced and applied by research groups from different areas, such as bioprocesses and biotechnology. Moreover, there has been an increased amount of research groups focused in the study of microalgae as a sustainable source for bioremediation, synthesis of bioproducts and development of bioenergy. Innovative strategies are combining the knowledge of basic sciences on microalgae into their applied processes, resulting in the progression of many applications that hopefully, will achieve the necessary degree of optimization for economically feasible large-scale applications. Advances on the areas of basic microalgae biology and novelties on the essential cellular processes were revealed. Progress in the applied science showed the use of the basic science knowledge into fostering translational research, proposing novel strategies for a sustainable world scenario. In this present e-book, articles presented by research groups from different scientific areas showed, successfully, the increased development of the microalgae research. Herewith, you will find articles ranging from bioprospecting regional microalgae species, through advances in microalgae molecular physiology to the development of techniques for characterization of biomass and the use of biomass into agriculture and bioenergy production. This e-book is an excellent source of knowledge for those working with microalgae basic and applied sciences, and a great opportunity for researchers from both areas to have an overview of the amazing possibilities we have for building an environmentally sustainable future once the knowledge is translated into novel applications.