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Protein Kinase Inhibitors As Sensitizing Agents For Chemotherapy

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Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy Book
Author : Anonim
Publisher : Academic Press
Release : 2018-11-21
ISBN : 0128127384
Language : En, Es, Fr & De

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Book Description :

Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, the fourth volume in the Cancer Sensitizing Agents for Chemotherapy Series, focuses on strategic combination therapies that involve a variety of tyrosine kinase inhibitors working together to overcome multi-drug resistance in cancer cells. The book discusses several tyrosine kinase inhibitors that have been used as sensitizing agents, such as EGFR, BCR-ABL, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic, and molecular mechanisms' emphases. This book is a valuable source for oncologists, cancer researchers and those interested in applying new sensitizing agents to their research in clinical practice and in trials. Summarizes the sensitizing role of some tyrosine kinase inhibitors in existing research Brings recent findings in several cancer types, both experimental and clinically, with a particular emphases on underlying biochemical, genetic, and molecular mechanisms Provides an updated and comprehensive knowledge regarding the field of combinational cancer treatment

pH Interfering Agents as Chemosensitizers in Cancer Therapy

pH Interfering Agents as Chemosensitizers in Cancer Therapy Book
Author : Claudiu Supuran,Simone Carradori
Publisher : Academic Press
Release : 2020-09-15
ISBN : 0128209283
Language : En, Es, Fr & De

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Book Description :

pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological applications. The book is structured with innovative outlines and a distinction between experimental and clinical results. The continuous discovery and assessment of the role played by old/new synthetic drugs, natural compounds and technological applications has led to the urgent need of classification in terms of biological activity, mechanism of action, clinical outcomes, cancer cell lines sensible to the treatment, and potentialities to better orient research in this field. Moreover, all the aspects relevant for medicinal chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, and molecular modeling studies) are strictly considered. Presents a broad view of the topic according to a medicinal chemistry-based approach beyond syntheses and biological assays, focusing on SAR studies, chemoinformatic, drug targeting and molecular modeling Explains the mechanism of action of the chemosensitizers by means of schemes and figures to facilitate comprehension Discusses novel targets to explore new possibilities that enhance research in the field

Medicinal Chemistry and Drug Discovery Chemotherapeutic agents

Medicinal Chemistry and Drug Discovery  Chemotherapeutic agents Book
Author : Alfred Burger
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Medicinal Chemistry and Drug Discovery Chemotherapeutic agents book written by Alfred Burger, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chemical Abstracts

Chemical Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Chemical Abstracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Anticancer Research

Anticancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cancer Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

International Journal of Oncology

International Journal of Oncology Book
Author : Anonim
Publisher : Unknown
Release : 2007-11
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Annual Meeting of the American Association for Cancer Research

Annual Meeting of the American Association for Cancer Research Book
Author : American Association for Cancer Research
Publisher : Unknown
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Contains abstracts of the scientific proceedings of the 73rd- annual meetings of the American Association for Cancer Research (1982- ).

Medical Subject Headings

Medical Subject Headings Book
Author : Anonim
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Contains records of chemicals which have been mentioned in a significant way in journals indexed in MEDLINE.

Excerpta Medica

Excerpta Medica Book
Author : Anonim
Publisher : Unknown
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Cancer Biotherapy

Cancer Biotherapy Book
Author : Annie Young,Lewis Rowett,David Kerr
Publisher : Oxford University Press
Release : 2006-05-04
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Recent advances in biology and immunology have opened up new horizons in both our understanding of cancer as a disease, and the potential for cancer therapy. These major developments mean that chemotherapy, radiotherapy and surgery are no longer the only options. Biotherapy, or biological therapy, is now regarded as the fourth treatment modality for patients with cancer. It utilises the great increase in our knowledge of molecular biology, cell biology and immunology to achieve tumour control. New biological agents are currently being used to treat cancer, such as monoclonal antibodies and vaccine therapies to stimulate the body's immune system to attack cancer cells. Biotherapy may be targeted to act specifically on cancer cells. Drugs such as monoclonal antibodies can be designed to recognize and find a particular type of cancer cell, attach itself to them, and destroy them. Naturally occuring biological molecules such as cytokines are also used, and the manipulation of normal biological mechanisms to control or inhibit tumour growth is another key feature of biotherapy. Edited by a team with perspectives in pharmacology, oncology and nursing, and with contributions from experts in the various areas of biotherapy, this book serves as an introduction to the subject. It includes the principles behind biological therapy, with discussion of the impact on the future of the fight against cancer. It has a strong clinical focus, describing the relevant biology and immunology while highlighting clinical relevance and treatment issues.

Rhinology

Rhinology Book
Author : Anonim
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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The Journal of Immunology

The Journal of Immunology Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Rituximab chimeric Anti CD20 Monoclonal Antibody Rituxan mediated Signal Transduction Pathways in Non hodgkin s Lymphoma NHL

Rituximab  chimeric Anti CD20 Monoclonal Antibody  Rituxan  mediated Signal Transduction Pathways in Non hodgkin s Lymphoma  NHL  Book
Author : Alireza Jazirehi
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Rituximab chimeric Anti CD20 Monoclonal Antibody Rituxan mediated Signal Transduction Pathways in Non hodgkin s Lymphoma NHL book written by Alireza Jazirehi, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Hadrontherapy in Oncology

Hadrontherapy in Oncology Book
Author : Ugo Amaldi,Börje Larsson
Publisher : Elsevier Science Limited
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This text provides an overview and analysis of the present state of research and development in hadrontherapy, with the intention of promoting the clinical introduction of ion accelerator technology for the benefit of cancer patients in various parts of the world.

EJB Reviews

EJB Reviews Book
Author : Anonim
Publisher : Unknown
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download EJB Reviews book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Oncology

Oncology Book
Author : Anonim
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Industrial Pharmaceutical Biotechnology

Industrial Pharmaceutical Biotechnology Book
Author : Heinrich Klefenz
Publisher : Wiley-VCH
Release : 2002-04-22
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This volume focuses on pharmaceutical biotechnology as a key area of life sciences. The complete range of concepts, processes and technologies of biotechnology is applied in modern industrial pharmaceutical research, development and production. The results of genome sequencing and studies of biological-genetic function are combined with chemical, micro-electronic and microsystem technology to produce medical devices and diagnostic biochips. A multitude of biologically active molecules is expanded by additional novel structures created with newly arranged gene clusters and bio-catalytic chemical processes. New organisational structures in the co-operation of institutes, companies and networks enable faster knowledge and product development and immediate application of the results of research and process development. This book is the ideal source of information for scientists and engineers in research and development, for decision-makers in biotech, pharma and chemical corporations, as well as for research institutes, but also for founders of biotech companies and people working for venture capital corporations.

The Lymphomas

The Lymphomas Book
Author : George Peter Canellos,Thomas Andrew Lister,Bryan D. Young
Publisher : Saunders
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Edited and written by world authorities, this text encompasses all aspects of Hodgkin's disease, non-Hodgkin's lymphomas, and related disorders. Designed to be the "Bible" for both clinicians and scientists who deal with lymphoma, the book is packed with useful summary tables and abundant illustrations and translates cutting-edge discoveries into state-of-the-art management guidelines. The preeminent names in research and practice bring together today's entire spectrum of knowledge--from epidemiology, classification and prognosis through diagnosis and therapy, including the latest scientific advances, such as the impact of molecular biologic and genetic discoveries and new biologic markers. Covers molecular biology bone marrow transplantationlymphoma in AIDS and Hodgkins disease. Provides in-depth coverage of the underlying biology of the disease as well as etiology, pathology, diagnosis, and treatment. Discusses advances in the treatment of diseases including radiotherapy, radiolabeled monoclonal antibodies, treatment of cutaneous lymphoma, and metastatic disease. Contains precise clinical how-tos for managing bone marrow transplantation and diseases that resemble lymphomas. Includes the recently codified new WHO classification of all lymphoid entities. Offers new and updated information on the biology and recategorization (morphologic, clinical, genotypic/immunophenotypic) of distinct lymphoma entities.