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Prognostic And Therapeutic Applications Of Rkip In Cancer

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Prognostic and Therapeutic Applications of Rkip in Cancer

Prognostic and Therapeutic Applications of Rkip in Cancer Book
Author : Benjamin Bonavida,Stavroula Baritaki
Publisher : Academic Press
Release : 2020-03-02
ISBN : 0128196122
Language : En, Es, Fr & De

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Book Description :

Prognostic and Therapeutic Applications of RKIP in Cancer provides updated reviews on the chemistry, signaling, pre-clinical and clinical activities, and role of RKIP expression levels for diagnostics, prognosis and potential interventions. The development of novel compounds and conjugates that selectively induce RKIP expression in cancer open a novel era of new therapeutics and their potential in the treatment of highly resistant cancers and metastases. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. Provides an update from experts in the field on diagnostics, prognostics and therapeutics Brings a clear overview of recent findings and references, as well as summaries, significant molecular pathways, and conclusions in each chapter Provides a general introductory chapter on contributions in the field and a chapter summary, with synthesized findings and a projection of future goals

Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas

Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas Book
Author : M. A. Hayat
Publisher : Elsevier
Release : 2005-01-31
ISBN : 0080495206
Language : En, Es, Fr & De

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Book Description :

Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. This book is the second volume of three planned, individually-sold volumes on this topic. Like Volume 1, this book fully explains the principles and applications of modern techniques used in the field of molecular genetics. It will be of particular interest to pathologists and molecular pathologists conducting both academic and/or clinical research. The only book available that translates molecular genetics into cancer diagnosis The results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations Methods discussed were either developed or refined by expert contributors in their own laboratories

Nitric Oxide NO and Cancer

Nitric Oxide  NO  and Cancer Book
Author : Benjamin Bonavida
Publisher : Springer Science & Business Media
Release : 2010-06-16
ISBN : 9781441914323
Language : En, Es, Fr & De

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Book Description :

Nitric Oxide (NO) is a pleitropic, ubiquitous modulator of cellular functions. Aryl nitrite and glyceryl trinitrate, representative intravasadilators, were introduced as therapeutic agents more than a century ago for relief from acute attacks of angina. The vasodilator action is mediated by the release of NO following treatment. NO has important therapeutic applications in several diseases such as inflammatory diseases, erectile dysfunction, inflammation, pain and neural protective activity. However, the role of NO in cancer and its application in therapy has received little attention. This monograph will be the first to focus on studies that investigate the role of NO in tumor cell pathogenesis, growth, angiogenesis, response to cytotoxic therapies and NO translational applications in cancer therapy, alone or in conjunction with other therapies.

Methods of Cancer Diagnosis Therapy and Prognosis

Methods of Cancer Diagnosis  Therapy and Prognosis Book
Author : M. A. Hayat
Publisher : Springer Science & Business Media
Release : 2009-03-28
ISBN : 1402095457
Language : En, Es, Fr & De

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Book Description :

This fourth volume in a series devoted to cancer treatment discusses various methodologies for the diagnosis, therapy and prognosis of colorectal cancer. It covers the latest information including standard and emerging therapies and technological advances.

The Role of ncRNAs in Solid Tumors Prognosis From Laboratory To Clinical Utility

The Role of ncRNAs in Solid Tumors Prognosis  From Laboratory To Clinical Utility Book
Author : Jian-Guo Zhou,Zhaohui Huang,Ondrej Slaby,Alfons Navarro
Publisher : Frontiers Media SA
Release : 2021-03-23
ISBN : 2889666093
Language : En, Es, Fr & De

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Book Description :

Download The Role of ncRNAs in Solid Tumors Prognosis From Laboratory To Clinical Utility book written by Jian-Guo Zhou,Zhaohui Huang,Ondrej Slaby,Alfons Navarro, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Application of Bioinformatics in Cancers

Application of Bioinformatics in Cancers Book
Author : Chad Brenner
Publisher : MDPI
Release : 2019-11-20
ISBN : 3039217887
Language : En, Es, Fr & De

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Book Description :

This collection of 25 research papers comprised of 22 original articles and 3 reviews is brought together from international leaders in bioinformatics and biostatistics. The collection highlights recent computational advances that improve the ability to analyze highly complex data sets to identify factors critical to cancer biology. Novel deep learning algorithms represent an emerging and highly valuable approach for collecting, characterizing and predicting clinical outcomes data. The collection highlights several of these approaches that are likely to become the foundation of research and clinical practice in the future. In fact, many of these technologies reveal new insights about basic cancer mechanisms by integrating data sets and structures that were previously immiscible. Accordingly, the series presented here bring forward a wide range of artificial intelligence approaches and statistical methods that can be applied to imaging and genomics data sets to identify previously unrecognized features that are critical for cancer. Our hope is that these articles will serve as a foundation for future research as the field of cancer biology transitions to integrating electronic health record, imaging, genomics and other complex datasets in order to develop new strategies that improve the overall health of individual patients.

Nitric Oxide and Cancer Pathogenesis and Therapy

Nitric Oxide and Cancer  Pathogenesis and Therapy Book
Author : Benjamin Bonavida
Publisher : Springer
Release : 2015-05-12
ISBN : 3319136119
Language : En, Es, Fr & De

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Book Description :

Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer.

Recent Advances in Cancer Research and Therapy

Recent Advances in Cancer Research and Therapy Book
Author : Xin-Yuan Liu,Sidney Pestka,Yu-Fang Shi
Publisher : Elsevier
Release : 2012-05-18
ISBN : 012397836X
Language : En, Es, Fr & De

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Book Description :

Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.

Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2009-11
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cancer Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Epithelial to Mesenchymal Transition EMT in Cancer

The Epithelial to Mesenchymal Transition  EMT  in Cancer Book
Author : Joëlle Roche
Publisher : MDPI
Release : 2018-04-09
ISBN : 3038427934
Language : En, Es, Fr & De

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Book Description :

This book is a printed edition of the Special Issue "The Epithelial-to-Mesenchymal Transition (EMT) in Cancer" that was published in Cancers

Ovarian Cancer

Ovarian Cancer Book
Author : Omer Devaja,Andreas Papadopoulos
Publisher : BoD – Books on Demand
Release : 2018-10-24
ISBN : 1789843332
Language : En, Es, Fr & De

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Book Description :

Ovarian cancer management is a rapidly changing field with new treatment agents available as a result of a greater understanding of the pathogenesis of this disease. In addition, both surgical and chemotherapeutic treatment strategies are evolving to maximise response in this disease. This book brings together leading specialists from around the world to discuss and outline a variety of new concepts in ovarian cancer, ranging from molecular biology and genetics through screening to both surgical and chemotherapeutic management.

Tumor Vascularization

Tumor Vascularization Book
Author : Domenico Ribatti,Francesco Pezzella
Publisher : Academic Press
Release : 2020-01-21
ISBN : 0128194944
Language : En, Es, Fr & De

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Book Description :

Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels. Explains new, non-orthodox concepts recently developed and related to the modality of growth of tumor blood vessels Provides information on the types of angiogenesis, non-angiogenesis dependent growth and vascular co-option, discussing both their similarities and differences Encompasses a discussion on clinical implications of tumor vascularization to translate research findings into treatment

HPV Infection in Head and Neck Cancer

HPV Infection in Head and Neck Cancer Book
Author : Wojciech Golusiński,C. René Leemans,Andreas Dietz
Publisher : Springer
Release : 2016-10-03
ISBN : 3319435809
Language : En, Es, Fr & De

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Book Description :

This book is exceptional in presenting an interdisciplinary approach to the subject of human papillomavirus (HPV) infection in the context of head and neck cancer. Leading experts in the field discuss the epidemiology and molecular biology of HPV-positive head and neck squamous cell carcinoma, HPV testing, the nonsurgical and surgical treatment of HPV-positive tumors, predictive factors for outcome and quality of life, and ongoing trials on the effectiveness of vaccination in disease prevention. It also provides recommendations for testing, diagnosis treatment and vaccination. Otolaryngologists, head and neck surgeons, medical oncologists, radiation oncologists, molecular biologists and pathologists will find this book a valuable resource.

Advancements of Mass Spectrometry in Biomedical Research

Advancements of Mass Spectrometry in Biomedical Research Book
Author : Alisa G. Woods,Costel C. Darie
Publisher : Springer
Release : 2014-06-20
ISBN : 3319060686
Language : En, Es, Fr & De

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Book Description :

This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.

Clinical Radiation Oncology

Clinical Radiation Oncology Book
Author : Leonard L. Gunderson
Publisher : Elsevier Health Sciences
Release : 2015-08-12
ISBN : 0323240984
Language : En, Es, Fr & De

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Book Description :

Radiation oncology for physicians and residents needing a multidisciplinary, treatment-focused resource; this updated edition provides the latest knowledge in this consistently growing field. You will broaden your understanding of the basic biology of disease processes, and access updated treatment algorithms, information on techniques, and state-of-the-art modalities.

Cancer and Pregnancy

Cancer and Pregnancy Book
Author : A. Surbone,F. Peccatori,N. Pavlidis
Publisher : Springer Science & Business Media
Release : 2007-11-09
ISBN : 3540712747
Language : En, Es, Fr & De

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Book Description :

This book is written by experts with clinical expertise on diagnosis, treatment, and follow-up of women with cancer during pregnancy. It provides a comprehensive review of data and an overview of psychological, ethical, and social aspects. Chapters address the diagnosis, treatment, and follow-up of women with solid or hematologic cancers. The safety of subsequent pregnancy and the maintenance or enhancement of fertility in women undergoing cancer therapy are also addressed.

Biomarkers in Breast Cancer

Biomarkers in Breast Cancer Book
Author : Giampietro Gasparini,Daniel F. Hayes
Publisher : Springer Science & Business Media
Release : 2008-01-17
ISBN : 159259915X
Language : En, Es, Fr & De

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Book Description :

Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.

Acute Myeloid Leukemia

Acute Myeloid Leukemia Book
Author : Christoph Röllig,Gert J. Ossenkoppele
Publisher : Springer Nature
Release : 2021-05-18
ISBN : 3030726762
Language : En, Es, Fr & De

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Book Description :

This book, written by a team of leading experts, provides a comprehensive overview of acute myeloid leukemia (AML), the most frequent acute leukemia in adults. The opening chapters present current knowledge of epidemiology, etiologic factors, and the pathogenesis and molecular development of AML. Detailed guidance is offered on laboratory and clinical diagnostic workup and disease classification, and the patient- and disease-related factors that determine prognosis and treatment allocation are identified. On the basis of these general considerations, initial treatments in patients considered fit for intensive treatment and in older and co-morbid patients are reviewed, and the available relapse treatment strategies, explained. For all clinical scenarios, the most recent data on the optimal use of newly approved agents in different AML subgroups are presented. Separate chapters address the treatment of acute promyelocytic leukemia, current practice of allogeneic stem cell transplantation, and special clinical situations. Finally, promising approaches in drug development, current standards and challenges in assessment of measurable residual disease, immune approaches, and ideas for innovative trial designs are considered.

Cancer Epigenetics

Cancer Epigenetics Book
Author : Mukesh Verma
Publisher : Humana Press
Release : 2014-11-25
ISBN : 9781493918034
Language : En, Es, Fr & De

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Book Description :

This volume shares technologies that detect common epigenetic changes which are very important in the early detection, progression, and prognosis of cancer as well as the design of new therapeutic tools against cancer cells. Beginning with a bit of background on epigenetic mechanisms, Cancer Epigenetics: Risk Assessment, Diagnosis, Treatment, and Prognosis continues with cancer specific type epigenetic change, methods and technologies used for detecting epigenetic changes, factors that influence epigenetic changes in cancer, as well as a final section on future directions in the field. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detailed implementation advice that guarantees easily reproducible results. Comprehensive and practical, Cancer Epigenetics: Risk Assessment, Diagnosis, Treatment, and Prognosis provides the most up-to-date knowledge of epigenetics and its implication in cancer prevention by risk assessment and screening and cancer control by treatment.

Nutritional Management of Renal Disease

Nutritional Management of Renal Disease Book
Author : Joel D. Kopple,Shaul G Massry,Kamyar Kalantar-Zadeh,Denis Fouque
Publisher : Academic Press
Release : 2021-10-08
ISBN : 0128185414
Language : En, Es, Fr & De

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Book Description :

Nutritional Management of Renal Disease, Fourth Edition, offers in-depth reviews of the metabolic and nutritional disorders prevalent in patients with renal disease and serves as an in-depth reference source concerning nutrition and kidney disease. This classic translational reference provides correct diagnosis - and therefore correct treatment - of renal, metabolic, and nutritional disorders. Nephrologists, diebetologists, endocrinologists, dieticians, and nutritionists depend on a strong understanding of the molecular basis for the disease. This fourth edition includes thorough new case reports, offering expert advice on how to use the latest research and clinical findings in counseling patients about dietary and lifestyle options. Readers gain insight into which treatments, medications, and diets to use based on the history, progression, and genetic make-up of a patient. Includes the latest comprehensive KDOQI clinical practice guidelines for the nutritional management of kidney disease from the National Kidney Foundation and the Academy of Nutrition and Dietetics, covering recommendations for each essential nutrient, as well as for some nonessential nutrients Presents a comprehensive, translational look at all aspects of metabolic and nutritional disorders in one reference Provides a common language for nephrologists, nutritionists, endocrinologists, and other interested physicians to assimilate information and discuss the underlying research and translation of best practices for the nutritional management and prevention of renal disease Saves clinicians and researchers time in quickly accessing the very latest details on nutritional practice as opposed to searching through thousands of journal articles. ~