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Probiotics In The Prevention Management Of Human Diseases

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Probiotics in The Prevention and Management of Human Diseases

Probiotics in The Prevention and Management of Human Diseases Book
Author : Mitesh Kumar Dwivedi,N. Amaresan,A Sankaranaryanan,Helen Kemp
Publisher : Academic Press
Release : 2021-12-02
ISBN : 0128237341
Language : En, Es, Fr & De

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Book Description :

Probiotics in The Prevention and Management of Human Diseases: A Scientific Perspective addresses the use of probiotics and their mechanistic aspects in diverse human diseases. In particular, the mechanistic aspects of how these probiotics are involved in mitigating disease symptoms (novel approaches and immune-mechanisms induced by Probiotics), clinical trials of certain probiotics, and animal model studies will be presented through this book. In addition, the book covers the role of probiotics in prevention and management aspects of crucial human diseases, including multidrug resistant infections, hospital acquired infections, allergic conditions, autoimmune diseases, metabolic disorders, gastrointestinal diseases, neurological disorders, and cancers. Finally, the book addresses the use of probiotics as vaccine adjuvants and as a solution for nutritional health problems and describes the challenges of using probiotics in management of human disease conditions as well as their biosafety concerns. Intended for nutrition researchers, microbiologists, physiologists, and researchers in related disciplines as well as students studying these topics require a resource that addresses the specific role of probiotics in the prevention and management of human disease. Contains information on the use of probiotics in significant human diseases, including antibiotic resistant microbial infections Presents novel applications of probiotics, including their use in vaccine adjuvants and concept of pharmabiotics Includes case studies and human clinical trials for probiotics in diverse disease conditions and explores the role of probiotics in mitigation of the symptoms of disease

Probiotics and Prebiotics in Human Nutrition and Health

Probiotics and Prebiotics in Human Nutrition and Health Book
Author : Venketeshwer Rao,Leticia Rao
Publisher : BoD – Books on Demand
Release : 2016-07-13
ISBN : 9535124757
Language : En, Es, Fr & De

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Book Description :

Probiotic microorganisms are recognised as being beneficial for human health. Prebiotics are substrates that are used preferentially by the probiotic bacteria for their growth. A great deal of interest has been generated in recent years in identifying probiotic bacteria and prebiotics, their characterization, mechanisms of action and their role in the prevention and management of human health disorders. Together they are referred to as synbiotic. This book is in response to the need for more current and global scope of probiotics and prebiotics. It contains chapters written by internationally recognized authors. The book has been planned to meet the needs of the researchers, health professionals, government regulatory agencies and industries. This book will serve as a standard reference book in this important and fast-growing area of probiotics and prebiotics in human nutrition and health.

Biofilms in Human Diseases Treatment and Control

Biofilms in Human Diseases  Treatment and Control Book
Author : Sunil Kumar,Niharika Chandra,Leena Singh,Muhammad Zaffar Hashmi,Ajit Varma
Publisher : Springer Nature
Release : 2019-11-19
ISBN : 3030307573
Language : En, Es, Fr & De

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Book Description :

This book highlights treatment strategies for bacterial biofilms in connection with a variety of human diseases. In particular, it reviews bacterial biofilm formation and its mechanism. Topics covered include biofilms in human health, the role of biofilms in mediating human diseases, and methods for testing bacterial biofilms. Further sections concentrate on biofilm-mediated diseases in different parts of the human gastrointestinal tract, while therapeutic strategies for biofilm control and natural agents that disrupt bacterial biofilms are also covered. Readers will also find the latest advances in probiotics and biofilms, as well as the use of probiotics to counteract biofilm-associated infections. Biofilms and antimicrobial resistance are discussed. Subsequent chapters address the management of inflammatory bowel disease via probiotics biofilms, as well as the role of probiotics bacteria in the treatment of human diseases associated with bacterial biofilms. The book is chiefly intended for clinicians/scientists in the fields of medical microbiology, applied microbiology, biochemistry, and biotechnology.

Functional Foods in Cancer Prevention and Therapy

Functional Foods in Cancer Prevention and Therapy Book
Author : Yearul Kabir
Publisher : Academic Press
Release : 2020-03-22
ISBN : 0128165383
Language : En, Es, Fr & De

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Book Description :

Functional Foods in Cancer Prevention and Therapy presents the wide range of functional foods associated with the prevention and treatment of cancer. In recent decades, researchers have made progress in our understanding of the association between functional food and cancer, especially as it relates to cancer treatment and prevention. Specifically, substantial evidence from epidemiological, clinical and laboratory studies show that various food components may alter cancer risk, the prognosis after cancer onset, and the quality of life after cancer treatment. The book documents the therapeutic roles of well-known functional foods and explains their role in cancer therapy. The book presents complex cancer patterns and evidence of the effective ways to control cancers with the use of functional foods. This book will serve as informative reference for researchers focused on the role of food in cancer prevention and physicians and clinicians involved in cancer treatment. Discusses the role of functional foods in cancer therapy Presents research-based evidence of the role of herbs and bioactive foods in cancer treatment and prevention Provides the most current, concise, scientific information regarding the efficacy of functional foods in preventing cancer and improving the quality of life Explores antioxidants, phytochemicals, nutraceuticals, herbal medicine and supplements in relation to cancer prevention and treatment Contains a clinical approach to the use of functional foods to prevent and treat cancer Emphasizes the role and mechanism of functional foods, including the characterization of active compounds on cancer prevention and treatment

Nutraceutical and Functional Foods in Disease Prevention

Nutraceutical and Functional Foods in Disease Prevention Book
Author : Keservani, Raj K.,Sharma, Anil K.,Kesharwani, Rajesh K.
Publisher : IGI Global
Release : 2018-07-13
ISBN : 1522532684
Language : En, Es, Fr & De

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Book Description :

Current research on health, nutrition, and preventative care will always be in demand. As the battles against ailments such as diabetes and heart disease continue, medical professionals are seeking to create a healthier society through nutrition and dietary-based tactics. Nutraceutical and Functional Foods in Disease Prevention is a comprehensive publication providing current research on the dynamic fields of pharmaceutical and biomedical science in relation to nutrition. This book examines the interactions and associations between nutritive value and its therapeutic applications in human health. Touching on topics such as the impact of probiotics in human health and disease treatment, recent trends in functional foods for obesity management, and the clinical role of antioxidants in the treatment of diseases, this title proves a valuable resource for academicians, healthcare practitioners, medical researchers, and higher education students preparing for careers as health professionals.

Nutrition Infection Interactions and Impacts on Human Health

Nutrition Infection Interactions and Impacts on Human Health Book
Author : Mohan Pammi,Jesus G. Vallejo,Steven A. Abrams
Publisher : CRC Press
Release : 2014-08-26
ISBN : 1466580496
Language : En, Es, Fr & De

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Book Description :

Nutrition and infection are often at a crossroads, interacting with each other and influencing human health. Infection is a major health problem and nutritional deficiency plays a significant role in increasing the risk of infection. Nutrition–Infection Interactions and Impacts on Human Health presents state-of-the-art evidence on nutrition–infection interactions and their impact on health and disease. The book explores a wide range of topics including the effects of infection on nutrition—a common occurrence in the developing world—and nutrient–infection interactions for specific infections including HIV, TB, malaria, and parasitic infections. These are reviewed with a special emphasis on nutritional interventions. Also covered is the role of the gastrointestinal tract and its influence on nutrition, focusing on the human gastrointestinal microbiota, enteric syndromes, probiotics, and immunonutrients. The book discusses infection–nutrition interactions in special age groups such as children, adolescents, and the elderly. It also reviews emerging nutritional and anti-infective strategies with an emphasis on future research directions. The book is useful for epidemiologists, nutritionists, and health care staff caring for patients. The book’s broad scope allows for its applicability to both the developed and the developing world.

Probiotic Bacteria and Their Effect on Human Health and Well Being

Probiotic Bacteria and Their Effect on Human Health and Well Being Book
Author : Alfredo Guarino,Eamonn M. M. Quigley,W. Allan Walker
Publisher : Karger Medical and Scientific Publishers
Release : 2013
ISBN : 3318023248
Language : En, Es, Fr & De

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Book Description :

An update on intestinal microbiota and probiotics Our microflora is an individual personal feature, providing a distinct tag to individuals. However, our intestinal microbiome is strongly affected by genetic, nutritional, and other external factors, and evolves with age. An effect of different microbial patterns on health appears very likely as there seem to be specific changes of intestinal microflora associated with various diseases. Specific microbial tags may thus be used as biomarkers of disease: to diagnose it, to monitor its evolution, and eventually to predict its response to treatment. This scenario opens the opportunity for targeting intestinal microflora using probiotics, both for prevention and treatment of an increasing number of conditions. Probiotic therapy is applied either as an adjunct to other treatments or as primary therapy, and evidence of efficacy is accumulating in several conditions, affecting either the intestine or nonintestinal organs. This publication provides an update on probiotics directed at physicians, biologists, biotechnologists, and researchers working in the food industry and agriculture, as well as in the environmental and basic sciences.

Probiotic Research in Therapeutics

Probiotic Research in Therapeutics Book
Author : Sandip V. Pawar,Praveen Rishi
Publisher : Springer Nature
Release : 2021-02-01
ISBN : 9813362367
Language : En, Es, Fr & De

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Book Description :

In a normal physiological state, several bacteria are present in the human gut that is essential to maintain the normal to healthy gastrointestinal function. Disturbances in this “normal flora” lead to gut inflammation and infection. This volume explores the potential of probiotics, the healthy bacteria, to manage gut-related diseases including gastrointestinal cancers, ulcerative colitis, H. pylori infections, and diarrhea; vaginosis; oral health; airway inflammation; and atopic dermatitis. The concept of designer probiotics, edible vaccines and future scope of research in the field is also presented. The animal models used for studying the benefits of probiotics in gut inflammation are described for beginners.

Bioprospecting of Microbial Diversity

Bioprospecting of Microbial Diversity Book
Author : Pradeep Verma,Maulin P. Shah
Publisher : Elsevier
Release : 2022-02-15
ISBN : 0323885756
Language : En, Es, Fr & De

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Book Description :

Bioprospecting of Microbial Diversity: Challenges and Applications in Biochemical Industry, Agriculture and Environment Protection gives a detailed insight into the utilization of microorganisms or microorganism-based bioactive compounds for the development of sustainable approaches, covering recent advances and challenges in the production and recovery of bioactive compounds such as enzymes, biopesticides, biofertilizers, biosensors, therapeutics, nutraceutical and pharmaceutical products. The challenges associated with the different approaches of microbial bioprospecting along with possible solutions to overcome these limitations are addressed. Further, the application of microbe-based products in the area of environmental pollution control and developing greener technologies are discussed. Providing valuable insight into the basics of microbial prospecting, the book covers established knowledge as well as genomic-based technological advancements to offer a better understanding of its application to various industries, promoting the commercialization of microbial-derived bioactive compounds and their application in biochemical industries, agriculture, and environmental protection studies. Describes the advanced techniques available for microbial bioprospecting for large-scale industrial production of bioactive compounds Presents recent advances and challenges for the application of microbe-based products in agriculture and environment pollution control Provides knowledge of microbial production of bioenergy and high-value compounds such as nutraceuticals and pharmaceuticals

Textbook of Gastroenterology

Textbook of Gastroenterology Book
Author : Tadataka Yamada
Publisher : John Wiley & Sons
Release : 2011-10-13
ISBN : 144435941X
Language : En, Es, Fr & De

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Book Description :

Over the past twenty years, thousands of physicians have come to depend on Yamada’s Textbook of Gastroenterology. Its encyclopaedic discussion of the basic science underlying gastrointestinal and liver diseases as well as the many diagnostic and therapeutic modalities available to the patients who suffer from them was—and still is—beyond compare. This new edition provides the latest information on current and projected uses of major technologies in the field and a new section on diseases of the liver. Plus, it comes with a fully searchable CD ROM of the entire content.

African Fermented Food Products New Trends

African Fermented Food Products   New Trends Book
Author : Abdel Moneim Elhadi Sulieman,Abdalbasit Adam Mariod
Publisher : Springer Nature
Release : 2022
ISBN : 3030829022
Language : En, Es, Fr & De

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Book Description :

Fermented foods play a major role in human nutrition and health, given the addition of flavor, improvement of texture, preservation against spoilage, and ease of digestion due to the fermentation process. This book provides information about the chemistry and bioactive compounds of African fermented food products, including their nutritional value and minor constituents. Chapters cover a wide range of topics, from the microorganisms involved in spontaneous fermentation to food safety considerations and quality assessment. The text can be used as a practical manual to better understand the nutritional and medicinal uses of various African fermented foods, as well as prepare recipes and product labels.

Advances in Probiotics for Sustainable Food and Medicine

Advances in Probiotics for Sustainable Food and Medicine Book
Author : Gunjan Goel,Ashok Kumar
Publisher : Springer Nature
Release : 2020-11-25
ISBN : 9811567956
Language : En, Es, Fr & De

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Book Description :

This book focuses on probiotics as sustainable foods and medicines, discussing issues such as screening and identification of probiotics, health claims, and advances in processing technologies, as well as food safety. Based on sound scientific research, the book is a unique reference resource for food scientists interested in development of probiotic based functional foods and their marketing. It will also appeal to those working in the area of regulations regarding the use of and health claims for fermented foods, both locally and globally.

Sleisenger and Fordtran s Gastrointestinal and Liver Disease E Book

Sleisenger and Fordtran s Gastrointestinal and Liver Disease E Book Book
Author : Mark Feldman,Lawrence S. Friedman,Lawrence J. Brandt
Publisher : Elsevier Health Sciences
Release : 2015-01-01
ISBN : 1455749893
Language : En, Es, Fr & De

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Book Description :

Consult this title on your favorite e-reader. Get the essential gastroenterology information you need from one authoritative source with an outstanding global reputation for excellence. Zero in on the key information you need to know with a consistent, full-color chapter design. Stay up to date with emerging and challenging topics: enteric microbiota and probiotics; fecal microbiota transplantation; Clostridium difficile colitis; and factitious gastrointestinal diseases. Incorporate the latest findings and improvements in care for liver disease patients—from diagnosis and treatment through post-treatment strategies and management of complications. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

Schlossberg s Clinical Infectious Disease

Schlossberg s Clinical Infectious Disease Book
Author : Cheston B. Cunha
Publisher : Oxford University Press
Release : 2022
ISBN : 0190888369
Language : En, Es, Fr & De

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Book Description :

Clinical Infectious Disease is the only comprehensive single-volume reference on clinical infectious disease for the busy medical practitioner. Now in its third edition, Clinical Infectious Disease provides rapid access to a practical overview of clinical infectious disease topics such as the susceptible host and nosocomial infection. Organized in topically relevant sections for ease of use and supported by full-color illustrations, this volume focuses on differential diagnosis, focused testing, and practical empiric and specific therapeutics in clinical infectious disease. It also features current research on medical microbiology, antimicrobial stewardship, and evolving treatments for COVID-19. Authoritative and accessible, Clinical Infectious Disease remains the "go to" desktop reference for daily clinical infectious disease problems.

Mandell Douglas and Bennett s Principles and Practice of Infectious Diseases

Mandell  Douglas  and Bennett s Principles and Practice of Infectious Diseases Book
Author : John E. Bennett, MD, MACP,Raphael Dolin, MD,Martin J. Blaser, MD
Publisher : Elsevier Health Sciences
Release : 2014-08-28
ISBN : 1455748013
Language : En, Es, Fr & De

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Book Description :

After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you'll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.

Gastrointestinal and Liver Disease Nutrition Desk Reference

Gastrointestinal and Liver Disease Nutrition Desk Reference Book
Author : Gerard E. Mullin,Laura E. Matarese,Melissa Palmer
Publisher : CRC Press
Release : 2011-09-12
ISBN : 1439812640
Language : En, Es, Fr & De

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Book Description :

While the gastrointestinal tract ingests, digests, and absorbs nutrients, the liver transforms nutrients, synthesizes plasma proteins, and detoxifies bacteria and toxins absorbed from the gut. It is therefore not surprising that gastrointestinal and hepatic diseases have a major impact on the nutritional state of the individual. Integrating nutrition and the gastrointestinal system, the Gastrointestinal and Liver Disease Nutrition Desk Reference brings together experts in the field of nutrition, gastroenterology, and hepatology to offer dietary, nutritional, and natural therapies for gastrointestinal and hepatic ailments in order to improve overall health. Providing a review of the digestive tract, liver, and core concepts, this important reference presents the nutritional consequences and considerations of digestive disorders. Contributors examine the role of nutrition in gastrointestinal and liver disease, including alcoholic and nonalcoholic liver disease, viral hepatitis, cirrhosis, malabsorption, colorectal disease, transplantation, pancreatitis, and inflammatory bowel disease. Of special interest to the practitioner are chapters on food allergy and intolerance, the effects of medicinal plants, and the role of fiber in the gastrointestinal tract. The reference also addresses the challenges of managing nutritional issues for hospitalized patients and covers eating disorders and ethical issues. Other key topics include: Obesity Clinical applications of probiotics The impact of micronutrient deficiencies Genomic applications for gastrointestinal care Drug-drug and drug-nutrient interactions Guidelines for performing a nutrition assessment This comprehensive reference offers a toolbox of key concepts, charts, tables, algorithms, and practical therapeutic strategies for practitioners involved in gastrointestinal and hepatic nutrition care. Dr. Mullin maintains a website discussing the integration of both Eastern and Western (conventional) medicines to help patients overcome their digestive illnesses.

Pediatric Gastrointestinal and Liver Disease E Book

Pediatric Gastrointestinal and Liver Disease E Book Book
Author : Robert Wyllie,Jeffrey S. Hyams,Marsha Kay
Publisher : Elsevier Health Sciences
Release : 2015-07-08
ISBN : 0323370217
Language : En, Es, Fr & De

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Book Description :

Consult the leading text in the field that delivers the information you need to diagnose and treat pediatric gastrointestinal and liver diseases effectively. In one convenient and comprehensive volume, Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay provide all the latest details on the most effective new therapies, new drugs, and new techniques in the specialty. In addition, the new two-color design throughout helps you find what you need quickly and easily. Full-color endoscopy images to help improve your visual recognition Definitive guidance from renowned international contributors who share their knowledge and expertise in this complex field Detailed diagrams that accurately illustrate complex concepts and provide at-a-glance recognition of disease processes More than 400 board review-style questions, answers, and rationales New therapies for hepatitis B and C, new drugs for the treatment of inflammatory bowel disease, and an expanded discussion of the newest endoscopic and motility techniques available for pediatric patients The most current information on diagnosing and treating abnormalities of protein, fat, and carbohydrate metabolism New chapters on pancreatic transplantation and liver pathology The latest surgical techniques for children with gastrointestinal conditions

Metabolism of Human Diseases

Metabolism of Human Diseases Book
Author : Eckhard Lammert,Martin Zeeb
Publisher : Springer Science & Business Media
Release : 2014-06-02
ISBN : 3709107156
Language : En, Es, Fr & De

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Book Description :

“Metabolism of Human Diseases” examines the physiology of key organs (e.g. brain, eye, lung, heart, blood vessels, blood, immune system, gastrointestinal tract, pancreas, liver, fat tissue, kidney, reproductive system, teeth, bone and joints) and how defective metabolism and signaling pathways within these organs contribute to common human diseases. The latter include depression, schizophrenia, epilepsy, Parkinson's disease, Alzheimer's disease, migraine, multiple sclerosis, Down syndrome, macular degeneration, glaucoma, asthma, COPD, pneumonia, atherosclerotic heart disease, heart failure, stroke, varicose veins, Sickle cell disease, hyperlipidemia, fever, sepsis, allergies, peptic ulcer, gastroenteritis, lactose intolerance, colon cancer, diabetes, cirrhosis, metabolic syndrome, hypertension, chronic kidney disease, gout, urinary tract infections, kidney stones, dental caries, osteoporosis, osteoarthritis, rheumatoid arthritis, breast cancer and prostate cancer. The book also describes commonly used drugs and explains their molecular targets. It provides the first comprehensive and detailed summary of the metabolism of individual organs and their physiological and pathological functioning. Thus it serves as a useful supplement to previous textbooks of human physiology. “Metabolism of Human Diseases” is a must-have, state-of-the-art textbook written by International experts for graduate students, postdocs and scientists in metabolic research, biochemistry, physiology and pharmacy as well as for physicians interested in molecular mechanisms underlying common human diseases.

Helicobacter pylori in Human Diseases

Helicobacter pylori in Human Diseases Book
Author : Shigeru Kamiya,Steffen Backert
Publisher : Springer Nature
Release : 2019-10-22
ISBN : 303021916X
Language : En, Es, Fr & De

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Book Description :

This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of Helicobacter pylori, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. H. pylori is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat H. pylori using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following H. pylori infection are still not fully understood. Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists.

Consultations in Feline Internal Medicine Volume 6 E Book

Consultations in Feline Internal Medicine  Volume 6   E Book Book
Author : John R. August
Publisher : Elsevier Health Sciences
Release : 2009-11-03
ISBN : 1437701884
Language : En, Es, Fr & De

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Book Description :

Completely revised and updated with 80 all-new chapters covering the most important information on current diagnostic, treatment, and preventive challenges facing feline practitioners today, Consultations in Feline Internal Medicine is an invaluable addition to every small animal clinician’s library. Full-color illustrations and expert contributions help you master and apply the latest advances in feline nutrition, emerging diseases, pet overpopulation, advanced imaging, and more with a comprehensive, clinically relevant approach. More than 100 worldwide leaders in small animal practice provide expert insight across the full spectrum of feline internal medicine. Extensive references make it easy to find additional information about specific topics most important to your practice. Current, evidence-based coverage reflects the latest findings and reports on pressing topics such as: Upper Respiratory Tract Aspergillosis Exocrine Pancreatic Insufficiency Diagnostic Imaging of the Ear Cardiac Blood Tests Urological Interventional Techniques A new section on feline nutrition highlights the impact of nutritional considerations on feline health. A dynamic full-color design, incorporating hundreds of NEW illustrations and tables, clarifies concepts and helps you interpret clinical data.