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Principles Of Heart Valve Engineering

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Principles of Heart Valve Engineering

Principles of Heart Valve Engineering Book
Author : Arash Kheradvar
Publisher : Academic Press
Release : 2019-08-28
ISBN : 0128146621
Language : En, Es, Fr & De

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Book Description :

Principles of Heart Valve Engineering is the first comprehensive resource for heart valve engineering that covers a wide range of topics, including biology, epidemiology, imaging and cardiovascular medicine. It focuses on valves, therapies, and how to develop safer and more durable artificial valves. The book is suitable for an interdisciplinary audience, with contributions from bioengineers and cardiologists that includes coverage of valvular and potential future developments. This book provides an opportunity for bioengineers to study all topics relating to heart valve engineering in a single book as written by subject matter experts. Covers the depth and breadth of this interdisciplinary area of research Encompasses a wide range of topics, from basic science, to the translational applications of heart valve engineering Contains contributions from leading experts in the field that are heavily illustrated

Calcific Aortic Valve Disease

Calcific Aortic Valve Disease Book
Author : Elena Aikawa
Publisher : BoD – Books on Demand
Release : 2013-06-12
ISBN : 9535111507
Language : En, Es, Fr & De

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Book Description :

Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

The Mechanics of Trans Catheter and Surgical Heart Valves

The Mechanics of Trans Catheter and Surgical Heart Valves Book
Author : Lakshmi Dasi,Lakshmi Prasad Dasi,Hoda Hatoum
Publisher : Academic Press
Release : 2020-06
ISBN : 9780128145548
Language : En, Es, Fr & De

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Book Description :

The Mechanics of Transcatheter and Surgical Heart Valves: A Guide for Engineers and Clinicians focuses on the fundamental principles of heart valve mechanics, providing a detailed picture of the pros and cons of current devices in the context of their biomechanics, biomaterials, patient complications, and their regulatory and fabrication aspects. The book covers methods and applications that will help readers innovate and design new cardiovascular technology. It is ideal for designers, testers and manufacturers, anyone working in the biomaterials industry on coatings or fabrication materials, or those researching mechanics and heart valve biology. Covers fluid mechanics, solid mechanics and biomaterials concepts Provides the only book on the market to offer this depth of information on prosthetic heart valves Includes flow visualization videos and high-speed valve imaging videos

Structural Insufficiency Anomalies in Cardiac Valves

Structural Insufficiency Anomalies in Cardiac Valves Book
Author : Kaan Kirali
Publisher : Unknown
Release : 2018-10-03
ISBN : 1789237661
Language : En, Es, Fr & De

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Book Description :

Download Structural Insufficiency Anomalies in Cardiac Valves book written by Kaan Kirali, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Aortic Valve

The Aortic Valve Book
Author : ManoJ. Thubrikar
Publisher : Routledge
Release : 2018-05-04
ISBN : 1351411403
Language : En, Es, Fr & De

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Book Description :

This book provides information on the aortic valve. Written in a comprehensive style, it emphasizes the principles behind the development of artificial valves. It covers the principles of valve geometry, tissue structure and function relationships, valve dynamics, fluid dynamics, mechanical stresses, echocardiographic images, mechanisms of valve sounds, valvular pathology, and design and performance of bioprosthetic valves. It enhances our understanding of angiographic and echocardiographic images and calcific stenosis, and will be of value in the development of better prostheses. The Aortic Valve is the ideal text for biomedical engineers and a unique resource for teaching interdisciplinary approaches to medical and engineering students. This work is also an indispensible source for cardiac surgeons, pathologists, cardiologists, and manufacturers of prosthetic valves.

Regenerative Medicine II

Regenerative Medicine II Book
Author : Ioannis V. Yannas
Publisher : Springer Science & Business Media
Release : 2005-03-29
ISBN : 9783540228684
Language : En, Es, Fr & De

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Book Description :

Organ regeneration, once unknown in adult mammals, is at the threshold of maturity as a clinical method for restoration of organ function in humans. Several laboratories around the world are engaged in the development of new tools such as stem cells and biologically active scaffolds. Others are taking fresh looks at well-known clinical problems of replacement of a large variety of organs: Bone, skin, the spinal cord, peripheral nerves, articular cartilage, the conjunctiva, heart valves and urologic organs. Still other investigators are working out the mechanistic pathways of regeneration and the theoretical implications of growing back organs in an adult. The time has come to present a collection of these efforts from leading practitioners in the field of organ regeneration.

Biofluid Mechanics

Biofluid Mechanics Book
Author : Ali Ostadfar
Publisher : Academic Press
Release : 2016-06-03
ISBN : 0128026006
Language : En, Es, Fr & De

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Book Description :

Biofluid Mechanics is a throrough reference to the entire field. Written with engineers and clinicians in mind, this book covers physiology and the engineering aspects of biofluids. Effectively bridging the gap between engineers’ and clinicians’ knowledge bases, the text provides information on physiology for engineers and information on the engineering side of biofluid mechanics for clinicians. Clinical applications of fluid mechanics principles to fluid flows throughout the body are included in each chapter. All engineering concepts and equations are developed within a biological context, together with computational simulation examples as well. Content covered includes; engineering models of human blood, blood rheology in the circulation system and problems in human organs and their side effects on biomechanics of the cardiovascular system. The information contained in this book on biofluid principles is core to bioengineering and medical sciences. Comprehensive coverage of the entire biofluid mechanics subject provides you with an all in one reference, eliminating the need to collate information from different sources Each chapter covers principles, needs, problems, and solutions in order to help you identify potential problems and employ solutions Provides a novel breakdown of fluid flow by organ system, and a quick and focused reference for clinicians

3D Bioprinting in Regenerative Engineering

3D Bioprinting in Regenerative Engineering Book
Author : Ali Khademhosseini,Gulden Camci-Unal
Publisher : CRC Press
Release : 2018-04-17
ISBN : 1315280477
Language : En, Es, Fr & De

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Book Description :

This book is comprehensive in nature with contributions by leading world experts in 3D bioprinting related to regenerative engineering. It includes history, incorporating the process and methods used in bioprinting. Significant sections will be reserved for the applications of the types of tissues generated by using bioprinting, along with an overview of different technologies used in bioprinting. In addition to equipment, the book also describes the different biomaterials and cells used in these approaches. Overall this is a book that includes both entry-level knowledge and advanced methods and techniques. Applications will emphasize engineering and clinical principles.

Animals and Medicine

Animals and Medicine Book
Author : Jack Botting
Publisher : Open Book Publishers
Release : 2015-05-04
ISBN : 1783741171
Language : En, Es, Fr & De

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Book Description :

Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives—both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine—from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer.This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.

Handbook of Tissue Engineering Scaffolds Volume Two

Handbook of Tissue Engineering Scaffolds  Volume Two Book
Author : Masoud Mozafari,Farshid Sefat,Anthony Atala
Publisher : Woodhead Publishing
Release : 2019-06-15
ISBN : 0081025629
Language : En, Es, Fr & De

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Book Description :

Handbook of Tissue Engineering Scaffolds: Volume Two provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems. Dedicated to the specialist topic of composite scaffolds, featuring all human body systems Covers basic fundamentals and advanced clinical applications Includes up-to-date information on preparation methodology and characterization techniques Highlights clinical data and case studies

Cardiovascular Mechanics

Cardiovascular Mechanics Book
Author : Michel R. Labrosse
Publisher : CRC Press
Release : 2018-09-13
ISBN : 1315280280
Language : En, Es, Fr & De

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Book Description :

The objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others. This information is conveyed through a comprehensive treatment of the overarching principles and theories that are behind mechanobiological processes, aortic and arterial mechanics, atherosclerosis, blood and microcirculation, hear valve mechanics, as well as medical devices and drugs. Examines all major theoretical and practical aspects of mechanical forces related to the cardiovascular system. Discusses a unique coverage of mechanical changes related to an aging cardiovascular system. Provides an overview of experimental methods in cardiovascular mechanics. Written by world-class researchers from Canada, the US and EU. Extensive references are provided at the end of each chapter to enhance further study. Michel R. Labrosse is the founder of the Cardiovascular Mechanics Laboratory at the University of Ottawa, where he is a full professor within the Department of Mechanical Engineering. He has been an active researcher in academia along with being heavily associated with the University of Ottawa Heart Institute. He has authored or co-authored over 90 refereed communications, and supervised or co-supervised over 40 graduate students and post-docs.

Principles of Tissue Engineering

Principles of Tissue Engineering Book
Author : Robert Lanza,Robert Langer,Joseph P. Vacanti
Publisher : Academic Press
Release : 2011-10-13
ISBN : 9780080548845
Language : En, Es, Fr & De

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Book Description :

First published in 1997, Principles of Tissue Engineering is the widely recognized definitive resource in the field. The third edition provides a much needed update of the rapid progress that has been achieved in the field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike. New to this edition: *Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves *Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems

Frontiers in Biomedical Engineering

Frontiers in Biomedical Engineering Book
Author : Ned H.C. Hwang,Savio L-Y Woo
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1441989676
Language : En, Es, Fr & De

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Book Description :

New Frontiers in Biomedical Engineering will be an edited work taken from the 1st Annual World Congress of Chinese Biomedical Engineers - Taipei, Taiwan 2002. As the economy develops rapidly in China and the Asian-Pacific population merges into the global healthcare system, many researchers in the West are trying to make contact with the Chinese BME scientists. At WCCBME 2002, invited leaders, materials scientists, bioengineers, molecular and cellular biologists, orthopaedic surgeons, and manufacturers from P.R. of China, Taiwan, Singapore and Hong Kong covered all five major BME domains: biomechanics, biomaterials and tissue engineering, medical imaging, biophotonics and instrumentation, and rehabilitation. This edited work taken from the World Congress proceedings will capture worldwide readership.

Catheterization and Interventional Cardiology in Adult Patients

Catheterization and Interventional Cardiology in Adult Patients Book
Author : Petr Widimsky,Harry Suryapranata,Alec Vahanian
Publisher : Oxford University Press
Release : 2010-10-28
ISBN : 0199558876
Language : En, Es, Fr & De

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Book Description :

This pocket book is focused on the practical aspects of cardiac catheterization and interventions including indications, periprocedural medications and techniques, interpretation of results, and the prevention and treatment of periprocedural complications.

Core Concepts in Cardiac Surgery

Core Concepts in Cardiac Surgery Book
Author : David Taggart,Yasir Abu-Omar
Publisher : Oxford University Press, USA
Release : 2018-11
ISBN : 0198735464
Language : En, Es, Fr & De

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Book Description :

The development of new techniques and the refinement of established procedures make cardiac surgery a fast-moving field. Core concepts in cardiac surgery has been developed to make it an invaluable textbook for the professional cardiac and cardiothoracic surgeon, covering both topical issuesand updates in cardiac surgery. This provides the practising cardiac surgeon with current updates in the field, and controversial issues that affect everyday practice. Written by an international team of renowned cardiac surgeons, each topic is split into a review of the current literature and then important technical details. Their wealth of professional experience has been distilled into tips and common pitfalls in practice throughout the book.Extensively illustrated with full-colour photographs and artwork to facilitate understanding of complex procedures, Core concepts in cardiac surgery is also available on a companion website, to allow the authors to update the text regularly to reflect developments in the discipline.

Cardiac Tissue Engineering

Cardiac Tissue Engineering Book
Author : Emil Ruvinov,Smadar Cohen,Yulia Sapir
Publisher : Morgan & Claypool Publishers
Release : 2012
ISBN : 1608452042
Language : En, Es, Fr & De

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Book Description :

Cardiac tissue engineering aims at repairing damaged heart muscle and producing human cardiac tissues for application in drug toxicity studies. This book offers a comprehensive overview of the cardiac tissue engineering strategies, including presenting and discussing the various concepts in use, research directions and applications. Essential basic information on the major components in cardiac tissue engineering, namely cell sources and biomaterials, is firstly presented to the readers, followed by a detailed description of their implementation in different strategies, broadly divided to cellular and acellular ones. In cellular approaches, the biomaterials are used to increase cell retention after implantation or as scaffolds when bioengineering the cardiac patch, in vitro. In acellular approaches, the biomaterials are used as ECM replacement for damaged cardiac ECM after MI, or, in combination with growth factors, the biomaterials assume an additional function as a depot for prolonged factor activity for the effective recruitment of repairing cells. The book also presents technological innovations aimed to improve the quality of the cardiac patches, such as bioreactor applications, stimulation patterns and prevascularization. This book could be of interest not only from an educational perspective (i.e. for graduate students), but also for researchers and medical professionals, to offer them fresh views on novel and powerful treatment strategies. We hope that the reader will find a broad spectrum of ideas and possibilities described in this book both interesting and convincing. Table of Contents: Introduction / The Heart---Structure, Cardiovascular Diseases, and Regeneration / Cell Sources for Cardiac Tissue Engineering / Biomaterials -- Polymers, Scaffolds, and Basic Design Criteria / Biomaterials as Vehicles for Stem Cell Delivery and Retention in the Infarct / Bioengineering of Cardiac Patches, \textit {In Vitro / Perfusion Bioreactors and Stimulation Patterns in Cardiac Tissue Engineering / Vascularization of Cardiac Patches / Acellular Biomaterials for Cardiac Repair / Biomaterial-based Controlled Delivery of Bioactive Molecules for Myocardial Regeneration

Tissue Engineered Vascular Grafts

Tissue Engineered Vascular Grafts Book
Author : Beat Walpoth,Helga Bergmeister,Gary Bowlin,Deling Kong,Joris Rotmans,Peter Zilla
Publisher : Springer
Release : 2020-10-11
ISBN : 9783030053352
Language : En, Es, Fr & De

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Book Description :

Cardiovascular diseases are still the leading cause of death in developed countries. Revascularization procedures such as coronary artery and peripheral bypass grafts, as well as access surgery represent a 2$ billion market yearly for the US alone. Despite intense research over many decades, no clinically suitable, shelf-ready, synthetic, vascular, small-caliber graft exists. There is therefore still a quest for such a clinical vascular prosthesis for surgical revascularization procedures and access surgery. Many approaches have been tried and are currently under investigation with promising results. These range from acellular and cell-based, stable or bio-degradable, synthetic scaffolds to biological or decellularized grafts, not forgetting self-assembly technologies for in vitro or in vivo VTE. All these approaches can be further enhanced by functionalization, e.g. with growth factors and drug elution. This updatable book aims to cover all the relevant aspects of Vascular Tissue Engineering (VTE) and novel alternatives to develop vascular grafts for clinical applications. The chapters in this book cover different aspects of manufacturing scaffolds with various polymers, mechanical characteristics, degradation rates, decellularization techniques, cell sheet assembly, 3-D printing and autologous mandril-based VTE. All the necessary in vitro tests such as biocompatibility and thrombogenicity are reviewed. Pre-clinical assessment of in vivo experimental models include patency, compliance, intimal hyperplasia, inflammatory reaction, cellular ingrowth and remodeling. Finally, early clinical trials will be periodically updated regarding results, regulatory aspects and post-marketing quality assessment. Furthermore, the reader should get an insight into various approaches, technologies and methods to better understand the complexity of blood surface and cell interactions in VTE. Translational research has yielded early human applications clearly showing the enormous need of research in the field to provide better solutions for our patients and this continuously updated book will hopefully become a reference in the field for life sciences.

Venous Valves

Venous Valves Book
Author : R. Gottlob,R. May
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 370918827X
Language : En, Es, Fr & De

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Book Description :

Venous valves rank among the smallest and most delicate organs of the human and animal bodies - so why devote an entire book to them? We were induced to do so by several reasons. First of all we would point out the clinical significance of venous valves. In the pathogenesis of a number of widespread diseases, such as varicose veins or the post-thrombotic syndrome, venous valves are involved as the underlying cause or at least a factor contributory to the symptoms. According to Taheri et al. these venous diseases occur ten times more frequently than arterial obliterations. Incompetence of venous valves also plays a causal role in varicocele, the most frequent cause of male infertility. But not only pathogenetic reasons induced us to write this book. In more recent times there has been a growing tendency to reconstruct functional valve disorders therapeutically; several surgical methods have been developed, which are critically reviewed in this book. It was our aim to sum up existing knowledge with respect to structure and function of venous valves and to expand that knowl edge by findings of our own. Examinations of semi-thin sections and unilayered en-face preparations have hardly been published so far, and systematic studies of the ultrastructure by electron-microscopy were not to be found in the literature. We are very grateful, therefore, to Dr. Silvana Geleff for having undertaken such a study upon our suggestion.

Heart Disease in Pregnancy

Heart Disease in Pregnancy Book
Author : Dawn Adamson,Mandish Dhanjal,Catherine Nelson-Piercy
Publisher : Oxford University Press
Release : 2011-03-17
ISBN : 0199574308
Language : En, Es, Fr & De

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Book Description :

A practical manual to aid the management of women with heart disease who are pregnant or who are considering pregnancy, Heart Disease in Pregnancy also provides an introduction to the physiological changes of pregnancy and the relevant obstetric knowledge and processes needed for a cardiologist to successfully manage a pregnant woman.

Principles of Regenerative Medicine

Principles of Regenerative Medicine Book
Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publisher : Academic Press
Release : 2010-12-16
ISBN : 9780123814234
Language : En, Es, Fr & De

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Book Description :

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs