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Principles Of Clinical Pharmacology

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Principles of Clinical Pharmacology

Principles of Clinical Pharmacology Book
Author : Arthur J. Atkinson
Publisher : Academic Press
Release : 2012
ISBN : 0123854717
Language : En, Es, Fr & De

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Book Description :

Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. * Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions. * Offers an expanded regulatory section that addresses US and international issues and guidelines. * Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response. * Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III.

Atkinson s Principles of Clinical Pharmacology

Atkinson s Principles of Clinical Pharmacology Book
Author : Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson, Jr.
Publisher : Academic Press
Release : 2021-03-15
ISBN : 9780128198698
Language : En, Es, Fr & De

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Book Description :

Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. Presents the essential knowledge for effective practice of Clinical Pharmacology Includes a new chapter and extended discussion on the role of Personalized and Precision Medicine in Clinical Pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also further discussion on "Phase 0" studies (microdosing) and PBPK

Melmon and Morrelli s Clinical Pharmacology

Melmon and Morrelli s Clinical Pharmacology Book
Author : Kenneth L. Melmon,Howard F. Morrelli,David F. Nierenberg
Publisher : McGraw Hill Professional
Release : 2000
ISBN : 9780071054065
Language : En, Es, Fr & De

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Book Description :

Perfect for the student, primary care practitioner, and pharmacist who needs both basic and clinical information to apply therapeutics A new overview chapter--plus practical steps required for optimal therapeutic decisions Coverage of newly emerging advances in therapeutics A new look at cost/benefit analysis of therapy Increased emphasis on drug interactions, and much more

Principles of Clinical Pharmacology

Principles of Clinical Pharmacology Book
Author : Arthur J. Atkinson, Jr.,Darrell R. Abernethy,Charles E. Daniels,Robert Dedrick,Sanford P. Markey
Publisher : Elsevier
Release : 2011-04-28
ISBN : 9780080466422
Language : En, Es, Fr & De

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Book Description :

This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products

Clinical Pharmacology

Clinical Pharmacology Book
Author : Morris J. Brown,Pankaj Sharma,Peter N. Bennett
Publisher : Elsevier Health Sciences
Release : 2012-07-30
ISBN : 0702051136
Language : En, Es, Fr & De

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Book Description :

A thorough knowledge of pharmacological and therapeutic principles is vital if drugs are to be used safely and effectively for increasingly informed patients. Those who clearly understand how drugs get into the body, how they produce their effects, what happens to them in the body, and how evidence of their therapeutic effect is assessed, will choose drugs more skilfully, and use them more safely and successfully than those who do not. Now in a fully revised 11th edition, Clinical Pharmacology is essential reading for undergraduate medical students, junior doctors and anyone concerned with evidence-based drug therapy. Introductory first three sections cover general principle of clinical pharmacology; five subsequent sections cover drug treatment of disease organised by body system. Retains approachable style set by the original author, Professor Laurence. Emphasis throughout is on evidence-based and safe drug prescribing. Indian Advisory Board will ensure content reflects the needs of the devloping world.

Clinical Pharmacology

Clinical Pharmacology Book
Author : Kenneth L. Melmon,Howard F. Morrelli
Publisher :
Release : 1978
ISBN : 9780023802706
Language : En, Es, Fr & De

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Book Description :

Anesthetic Pharmacology

Anesthetic Pharmacology Book
Author : Alex S. Evers,Mervyn Maze,Evan D. Kharasch
Publisher : Cambridge University Press
Release : 2011-03-10
ISBN : 1139497022
Language : En, Es, Fr & De

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Book Description :

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Clinical Pharmacology

Clinical Pharmacology Book
Author : Cynthia Webster
Publisher : Teton NewMedia
Release : 2001-03
ISBN : 9781893441378
Language : En, Es, Fr & De

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Book Description :

Presented in a highly visual style, this book offers an introduction to clinically relevant pharmacologic agents used in small and large animal practice. It includes an overview of key concepts in pharmacology including basic principles of pharmacodynamics, physiological uptake and nervous system perception. Various types of drugs are discussed, including: tranqulizers, sedatives and opiods. Pharmacologic effects, side effects, drug interactions and species differences are illustrated with emphasis on figures, charts and diagrams. Over 100 study questions test retention and comprehension. This "quick look" is well-presented, easy to follow, very concise and should be instrumental in developing a rudimentary understanding of pharmacological principles in animal medicine.

Clinical Pharmacology and Therapeutics

Clinical Pharmacology and Therapeutics Book
Author : Gerard A. McKay,Matthew R. Walters,Neil D. Ritchie
Publisher : John Wiley & Sons
Release : 2020-11-09
ISBN : 1119599970
Language : En, Es, Fr & De

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Book Description :

A must-have companion for medical students and junior doctors for almost four decades, Lecture Notes: Clinical Pharmacology and Therapeutics provides concise yet thorough coverage of the principles of clinical pharmacology, the major characteristics of therapeutics, and the practical aspects of prescribing drugs to alleviate symptoms and to treat disease. Whether you are preparing for examinations or prescribing to patients, the tenth edition offers readers current and authoritative insight into the essential practical and clinical knowledge. Logically organised chapters allow for rapid location of key information, while examples of commonly encountered scenarios illustrate how and when to use drugs in clinical situations. Throughout the text, practice questions, prescribing guidelines, and self-assessment tests clarify and reinforce the principles that inform appropriate clinical decision-making. Presents an up-to-date review of drug use across all major clinical disciplines Offers a timely overview of clinical drug trials and development Provides new clinical scenarios to relate chapter content to real-life application Contains colour-coded “Key Points” and “Prescribing Points” to highlight important information Includes chapter introductions and summaries, and numerous figures, tables, and colour illustrations Lecture Notes: Clinical Pharmacology and Therapeutics, Tenth Edition, is an essential resource for medical students, junior doctors, and other prescribers looking for an up-to-date reference on pharmacological principles, prescribing, and therapeutics.

Principles of Pharmacology

Principles of Pharmacology Book
Author : David E. Golan
Publisher : Lippincott Williams & Wilkins
Release : 2008
ISBN : 9780781783552
Language : En, Es, Fr & De

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Book Description :

This primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective for diseases in that organ system. Over 400 two-color illustrations show molecular, cellular, biochemical, and pathophysiologic processes underlying diseases and depict targets of drug therapy. Each Second Edition chapter includes a drug summary table presenting mechanism, clinical applications, adverse effects, contraindications, and therapeutic considerations. New chapters explain how drugs produce adverse effects and describe the life cycle of drug development. The fully searchable online text and an image bank are available on thePoint.

Concise Clinical Pharmacology

Concise Clinical Pharmacology Book
Author : Ben Greenstein,Adam Greenstein
Publisher : Pharmaceutical Press
Release : 2007
ISBN : 9780853695769
Language : En, Es, Fr & De

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Book Description :

This is a concise study guide and thorough introduction to clinical pharmacology from which students can gain a rapid understanding of individual topics within the discipline, and from which they can review and revise certain topics before exams. This is achieved through self-contained two-page "spreads" for each topic, with concise text on the left and a diagram on the right to elaborate and reinforce the text. To further underpin the text, additional two page spreads have been included where appropriate, with case histories on the left and Q&As on the right. The text has a strong clinical focus and, in the main, sections relate to particular body systems or the therapy of a disease-class (eg, cancer). Pharmacological principles and mechanisms are covered, but the main focus is on the therapeutic use of the drugs. Sections cover basic principles of pharmacology, specialised pharmacology (inc. in pregnancy, paediatrics, geriatrics), and the vitamins. The text has been written primarily for pharmacy students, but will also be of interest to clinical medical students. The strong clinical focus should also appeal to practitioners.

Clinical Pharmacology

Clinical Pharmacology Book
Author : Kenneth Lloyd Melmon,Howard F. Morrelli
Publisher :
Release : 1978
ISBN : 9780022802707
Language : En, Es, Fr & De

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Book Description :

Principles of Medical Pharmacology

Principles of Medical Pharmacology Book
Author : Harold Kalant,Denis Michael Grant,Jane Mitchell
Publisher : W B Saunders Company Canada Limited
Release : 2007
ISBN :
Language : En, Es, Fr & De

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Book Description :

This edition includes new case studies, overview chapters on second messenger systems and the nervous and cardiovascular systems, and sections on topics such as drug-resistant TB and pharmacogenetics.

Clinical Pharmacology

Clinical Pharmacology Book
Author : P. N. Bennett,Morris Jonathan Brown,Pankaj Sharma
Publisher : Churchill Livingstone
Release : 2012
ISBN : 9780702040849
Language : En, Es, Fr & De

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Book Description :

General -- From pharmacology to toxicology -- Infection and inflammation -- Nervous system -- Cardiorespiratory and renal systems -- Blood and neoplastic disease -- Gastrointestinal system -- Endocrine system, metabolic conditions.

Avery s Drug Treatment

Avery s Drug Treatment Book
Author : Graeme S. Avery,Trevor M. Speight
Publisher :
Release : 1987
ISBN : 9780864710246
Language : En, Es, Fr & De

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Book Description :

Small Animal Clinical Pharmacology

Small Animal Clinical Pharmacology Book
Author : Jill E. Maddison,Stephen W. Page,David Church (BVSc.)
Publisher : Elsevier Health Sciences
Release : 2008
ISBN : 0702028584
Language : En, Es, Fr & De

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Book Description :

Small Animal Clinical Pharmacology is a practical, clinically-oriented pharmacology text designed to provide the veterinary student and practitioner with all the relevant information needed when designing drug treatment regimens for pets in small animal veterinary practice. Comprehensively updated and revised, the second edition of this core text covers essential new information on drugs used in the management of a range of presenting conditions including heart disease and cardiac arrhythmias. For the second edition new authors, superb new illustrations and a second colour have all been introduced. With its unique approach combining a thorough understanding of the pharmacological action of drugs with a basic understanding of the relevant physiology and pathophysiology of systems and tissues affected, Small Animal Clinical Pharmacology continues to be an indispensable book for all veterinary students and practitioners. Organised by drug class in a uniform and detailed structure which means it is easy to locate key information on dose rates, routes of administration, drug interactions and special considerations at a glance Key chapters based around treatment of disorders of particular body systems, eg cardiovascular and thyroid disorders Essential introductory chapters covering pharmacokinetics, general pharmacological principles and adverse reactions for a thorough basic grounding in the subject All authors are experienced clinicians and recognised experts in their field who bring a down to earth and practical approach to the text

Clinical Pharmacology Made Ridiculously Simple

Clinical Pharmacology Made Ridiculously Simple Book
Author : James M. Olson
Publisher : Medmaster
Release : 2001
ISBN :
Language : En, Es, Fr & De

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Book Description :

A concise overview of the most important principles in clinical pharmacology, with drug comparisons in clear chart format. Excellent Board review

Pharmacology

Pharmacology Book
Author : Miles Hacker,William S. Messer,Kenneth A. Bachmann
Publisher : Academic Press
Release : 2009-06-19
ISBN : 9780080919225
Language : En, Es, Fr & De

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Book Description :

Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research. Uses individual drugs to explain molecular actions Full color art program explains molecular and chemical concepts graphically Logical structure reflecting the current state of pharmacology and translational research Covers such intricacies as drug resistance and cell death Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

Topics in Clinical Pharmacology and Therapeutics

Topics in Clinical Pharmacology and Therapeutics Book
Author : Robert F. Maronde
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461248647
Language : En, Es, Fr & De

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Book Description :

Dr. Maronde has performed a major service in bringing together a superb array of scholars and clinicians to discuss not only the basic principles in therapeutics and clinical pharmacology but also the application of those principles to a wide range of clinical problems. Inclusion of chapters on adverse drug reactions, drug overdose, nonmedical prescription drug use, physician prescribing patterns, and the pharmaceutical industry makes this a particularly valuable book for clinicians. It is increasingly important that clinicians be well grounded in the principles of pharmacodynamics and pharmacokinetics because more and more of our patients are aging and cannot be treated as young or middle-aged adults. Elderly patients are liable to either drug overdose or underdose if traditional dosage formulas are followed because of changes in drug metabolism, drug distribution within the body, drug excretion, or changes in receptor site sensitivity. Because the elderly often present with mUltiple chronic diseases and require a variety of medications, they are more prone to medication errors, drug-drug interactions, and adverse drug reactions. The inclusion of three excellent chapters relating to drug-drug interactions, adverse drug reactions, and drug overdose is most welcome and is a valuable addition to this outstanding text on therapeutics and clinical pharmacology. Adverse drug reactions present a potentially serious problem for any patient for whom drugs are prescribed and particularly for those who must take multiple prescriptions.

Modern Pharmacology with Clinical Applications

Modern Pharmacology with Clinical Applications Book
Author : Charles R. Craig,Robert E. Stitzel
Publisher : Lippincott Williams & Wilkins
Release : 2004
ISBN : 9780781737623
Language : En, Es, Fr & De

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Book Description :

Building on the strengths of previous editions, the Sixth Edition of Modern Pharmacology with Clinical Applications continues to provide an up-to-date and comprehensive textbook for students of pharmacology. Focusing on the clinical application of drugs within a context of the major principles of pharmacology, this text supplies both students and faculty with an introduction to modern pharmacotherapeutics.