Skip to main content

Principles And Practice Of Clinical Research

In Order to Read Online or Download Principles And Practice Of Clinical Research Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Principles and Practice of Clinical Research

Principles and Practice of Clinical Research Book
Author : John I. Gallin,Frederick P. Ognibene
Publisher : Academic Press
Release : 2012
ISBN : 0123821673
Language : En, Es, Fr & De

GET BOOK

Book Description :

This expanded third edition provides an introduction to the conduct of clinical research as well as more comprehensive and expansive content about the infrastructure necessary for a successful clinical research organization or enterprise. With authors who are experts in clinical research in both the public and private sectors, this publication provides essential information to clinical investigators who wish to develop and conduct well designed patient-based research protocols that comply with rigorous study design, ethical, and regulatory requirements.

Principles and Practice of Clinical Research

Principles and Practice of Clinical Research Book
Author : John I. Gallin,Frederick P Ognibene,Laura Lee Johnson
Publisher : Academic Press
Release : 2017-11-17
ISBN : 0128499044
Language : En, Es, Fr & De

GET BOOK

Book Description :

Principles and Practice of Clinical Research, Fourth Edition has been thoroughly revised to provide a comprehensive look at both the fundamental principles and expanding practice of clinical research. New to this edition of this highly regarded reference, authors have focused on examples that broadly reflect clinical research on a global scale while including a discussion of international regulations, studies, and implications. In addition to key topics such as bioethics, clinical outcome data, cultural diversity, protocol guidelines, and “omic platforms, this edition contains new chapters devoted to electronic health records and information resources for clinical researchers, as well as the many opportunities associated with big data. Covering a vast number of topics and practical advice for both novice and advanced clinical investigators, this book is a highly relevant and essential resource for all those involved in conducting research. Features input from experts in the field dedicated to translating scientific research from bench to bedside and back Provides expanded coverage of global clinical research Contains hands-on, practical suggestions, illustrations, and examples throughout Includes new chapters on the international regulation of drugs and biologics, the emergence of the important role of comparative effectiveness research and how to identify clinical risks and manage patient safety in a clinical research setting

Principles and Practice of Clinical Research

Principles and Practice of Clinical Research Book
Author : John I. Gallin,Frederick P Ognibene
Publisher : Elsevier
Release : 2011-04-28
ISBN : 9780080489568
Language : En, Es, Fr & De

GET BOOK

Book Description :

The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research *Delves into data management and addresses how to collect data and use it for discovery *Contains valuable, up-to-date information on how to obtain funding from the federal government

Principles and Practice of Clinical Trial Medicine

Principles and Practice of Clinical Trial Medicine Book
Author : Richard Chin,Bruce Y Lee
Publisher : Elsevier
Release : 2008-07-25
ISBN : 9780080557939
Language : En, Es, Fr & De

GET BOOK

Book Description :

Clinical trials are an important part of medicine and healthcare today, deciding which treatments we use to treat patients. Anyone involved in healthcare today must know the basics of running and interpreting clinical trial data. Written in an easy-to-understand style by authors who have considerable expertise and experience in both academia and industry, Principles and Practice of Clinical Trial Medicine covers all of the basics of clinical trials, from legal and ethical issues to statistics, to patient recruitment and reporting results. Jargon-free writing style enables those with less experience to run their own clinical trials and interpret data Book contains an ideal mix of theory and practice so researchers will understand both the rationale and logistics to clinical trial medicine Expert authorship whose experience includes running clinical trials in an academic as well as industry settings Numerous illustrations reinforce and elucidate key concepts and add to the book's overall pedagogy

Clinical Research

Clinical Research Book
Author : Manfred Stommel,Celia Wills
Publisher : Lippincott Williams & Wilkins
Release : 2004
ISBN : 9780781735186
Language : En, Es, Fr & De

GET BOOK

Book Description :

This unique textbook integrates statistical concepts into evidence-based clinical practice and patient management. Research concepts and techniques are drawn from epidemiology, bio-statistics, and psychometrics, as well as educational and social science research. Clinical examples throughout the text illustrate practical and scientifically sound applications of the concepts. Data tables and research vignettes highlight statistical distributions involving probability. Methods to locate and utilize web-based information relevant to clinical research are discussed, and web URLs are provided. Further learning is encouraged by the inclusion of suggested activities, recommended readings, references, and a comprehensive glossary of research terms. Additional resources are available at a Connection Website, connection.LWW.com/go/stommel.

Principles of Good Clinical Practice

Principles of Good Clinical Practice Book
Author : Michael J. McGraw,Shawn P. Shearn
Publisher : Pharmaceutical Press
Release : 2010
ISBN : 0853697906
Language : En, Es, Fr & De

GET BOOK

Book Description :

This text aims to be a one-stop source for guidance and checking the rules for proper conduct of clinical trials, as well as providing a historical perspective of the clinical research landscape. Good Clinical Practice guidelines provide an international quality standard for the regulation of clinical trials. They include standards on how clinical trials should be conducted, provide assurance of safety and efficacy of newly developed drugs and protect human rights. Principles of Good Clinical Practice describes the ethical principles and regulatory requirements that influence the current and future conduct of clinical research. As well as providing essential information on clinical trial design and pharmacovigilance, coverage also includes: informed consent; investigator and sponsor responsibilities; site monitoring; institutional review boards and dependent ethics committees; clinical trial registration and reporting; quality assurance; and future implications for good clinical practices. Principles of Good Clinical Practice will be a definitive text for Clinical Development personnel at pharmaceutical companies, Contract Research Organizations (CROs), PharmD and postgraduate pharmacy students, and medical, pharmacy and drug company libraries

Critical Thinking in Clinical Research

Critical Thinking in Clinical Research Book
Author : Felipe Fregni,Ben M.W. Illigens
Publisher : Oxford University Press
Release : 2018-03-13
ISBN : 0199324514
Language : En, Es, Fr & De

GET BOOK

Book Description :

One of the most crucial skills a clinician, scientist, or student can learn is to create, conduct, and interpret the conclusions of a clinical study. Critical Thinking in Clinical Research teaches these fundamentals in four distinct sections, called "units": the first unit focuses on issues surrounding the design of a study such as population, question selection, randomization, and blinding; Unit 2 presents statistical methods such as analyzing data collected, how to present and discuss the data concisely; the third unit covers practical aspects such as methodology, organizational considerations, principles of trial conduct and reporting; and the final unit delves into study designs, providing the advantages and drawbacks of each design style. Each chapter begins with a short introduction, followed by a hypothetical case that challenges the reader to make decisions, to consider pros and cons of specific approaches, and to evaluate options based on specific conditions. Knowing how to critically read and understand scientific papers and to collect, analyze, and interpret research data, which they in turn can then present in their own scientific manuscript makes this book the perfect resource for anyone looking to contribute to the wealth of scientific and medical inquiry.

Surgical Research

Surgical Research Book
Author : Hans Troidl,M.F. McKneally,David S. Mulder,Bucknam McPeek,W.O. Spitzer,A.S. Wechsler
Publisher : Springer Science & Business Media
Release : 1998
ISBN : 9780387946993
Language : En, Es, Fr & De

GET BOOK

Book Description :

A unique reference manual for academic surgeons, this book discusses every facet of surgical research. From getting grant money to choosing a topic, reviewing the literature, planning and conducting research, and reporting results.

Principles of Clinical Research

Principles of Clinical Research Book
Author : Institute of Clinical Research
Publisher : Routledge
Release : 2001
ISBN :
Language : En, Es, Fr & De

GET BOOK

Book Description :

In an arena which has seen rapid change over the past decade, this work provides a comprehensive and up-to-date guide to the planning, organization and management of clinical trials.

Principles and Practice of Pharmaceutical Medicine

Principles and Practice of Pharmaceutical Medicine Book
Author : Lionel D. Edwards,Anthony W. Fox,Peter D. Stonier
Publisher : John Wiley & Sons
Release : 2011-07-12
ISBN : 1444348124
Language : En, Es, Fr & De

GET BOOK

Book Description :

The new edition of Principles and Practice of Pharmaceutical Medicine is a comprehensive reference guide to all aspects of pharmaceutical medicine. New content includes chapters and coverage on regulatory updates, increasing international harmonization, transitional and probabilistic approaches to drug development, the growing sophistication and regulatory importance of pharmacovigilance, personalized medicine and growth in biotechnology as a source of new experimental drugs.

Clinical Research in Oral Health

Clinical Research in Oral Health Book
Author : William V. Giannobile,Brian A. Burt,Robert J. Genco
Publisher : John Wiley & Sons
Release : 2009-12-09
ISBN : 9780813820552
Language : En, Es, Fr & De

GET BOOK

Book Description :

Clinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvement.

Principles and Practice of Research

Principles and Practice of Research Book
Author : H. Troidl,W.O. Spitzer,B. McPeek,D.S. Mulder,Martin F. Bach
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642969429
Language : En, Es, Fr & De

GET BOOK

Book Description :

emerging on the surgical scene to challenge or For some readers, the title of this book will im thodoxy. Although these innovations are often mediately raise the question, what exactly is greeted with great optimism, a factual basis for meant by surgical research? In the very broadest that enthusiasm is sometimes far from secure sense the term can be taken to include all en and much further work is frequently required to deavors, however elementary or limited in discover whether we are dealing with genuine scope, to advance surgical knowledge. Ideally, advances or not. it refers to well-organized attempts to establish The most exciting and attractive scenario for on a proper scientific basis, i. e. , to place beyond surgical research is unquestionably one that de reasonable doubt, the truth or otherwise of any picts a successful attempt by a researcher to es concepts, old or new, within the ambit of sur gery, and, of course, anaesthesia. tablish the accuracy of some bold innovation for which he himself is responsible. Joseph Lister, The methods used to achieve that end vary demonstrating by clinical trial that wound sup enormously, depending on the issue being in vestigated.

Clinical Epidemiology

Clinical Epidemiology Book
Author : D. E. Grobbee,Arno W. Hoes
Publisher : Jones & Bartlett Learning
Release : 2009
ISBN : 0763753157
Language : En, Es, Fr & De

GET BOOK

Book Description :

In the current era of evidence-based medicine, clinical epidemiology is increasingly being recognized as an important tool in the critical appraisal of available evidence and the design of new studies. This book is a comprehensive resource that introduces the reader to the basics of clinical epidemiology. It explores the principles and methods that can be used to obtain quantitative evidence on the effects on interventions and on the diagnosis, etiology, and prognosis of disease.

Clinical Psychopharmacology

Clinical Psychopharmacology Book
Author : Nassir Ghaemi
Publisher : Oxford University Press, USA
Release : 2019-01-04
ISBN : 0199995486
Language : En, Es, Fr & De

GET BOOK

Book Description :

Clinical Psychopharmacology offers a comprehensive guide to clinical practice that explores two major aspects of the field: the clinical research that exists to guide clinical practice of psychopharmacology, and the application of that knowledge with attention to the individualized aspects of clinical practice. The text consists of 50 chapters, organized into 6 sections, focusing on disease-modifying effects, non-DSM diagnostic concepts, and essential facts about the most common drugs. This innovative book advocates a scientific and humanistic approach to practice and examines not only the benefits, but also the harms of drugs. Providing a solid foundation of knowledge and a great deal of practical information, this book is a valuable resource for practicing psychiatrists, psychiatric nurse practitioners, medical students and trainees in psychiatry, as well as pharmacists.

Manual for the Planning and Implementation of Therapeutic Studies

Manual for the Planning and Implementation of Therapeutic Studies Book
Author : S. Biefang,W. Köpcke,M.A. Schreiber
Publisher : Springer Science & Business Media
Release : 2013-03-13
ISBN : 3642932371
Language : En, Es, Fr & De

GET BOOK

Book Description :

The German edition of this manual appeared in 1979. Its main objective then was to extend help to those engaged in multiaentric therapeutic studies, especially with respect to the "Federal Government's Program on Promoting Research and Development in the Service of Health". Experience with therapeutic studies in the Federal Republic of Germany showed that considerable problems as to methods and implementation of such studies exist. The manual was an attempt to present current metho dological knowledge and the experience obtained from completed studies in the light of the international literature. No radically new methodo logy was produced; however, the information representing the state-of the art, which is widely scattered up to now, has been compiled. For the American edition of this manual a few changes have been made. These concern especially the literature where references to German un published manuscripts were omitted. The authors wish to thank Dr. Andreas Jaffe for the translation, and Evelyn Birke who typewrited the lecture-notes manuscrip~ • . GUnzburg and Munich Sibylle Biefang November 1981 Wolfgang Kopcke Martin A. Schreiber Contents Page Foreword 1. Methods of Therapeutic Studies 2 1. 1. Terminology 4 1. 2. Experimental Design 11 1. 3. Types of Studies 20 1. 4. Steps in Drug Testing 2. Checklist for the Planning, Implementation and Evaluation 22 of Therapeutic Studies 22 2. 1. Planning of Experiments 29 2. 2. Documentation 36 2. 3. Organization 41 2. 4. Statistical Analysis 44 2. 5.

G3P Good Privacy Protection Practice in Clinical Research

G3P   Good Privacy Protection Practice in Clinical Research Book
Author : Karl-Heinz Schriever,Markus Schröder
Publisher : Walter de Gruyter GmbH & Co KG
Release : 2014-10-02
ISBN : 311028328X
Language : En, Es, Fr & De

GET BOOK

Book Description :

Establishing ethical and privacy protection aspects in scientific research, especially in medical research, has a long history. Medical data are usually more sensible than other personal data and require therefore an even higher degree of protection than other personal data. In recent research projects genetic evaluations become more and more important and trigger thereby new and continuing activities in the context of data protection. Genetic data as a subset of medical data are the most sensible category of personal data and require therefore the highest degree of data protection. The book provides a systematic and itemized approach to data protection in clinical research including the handling of genetic material, genetic samples as well as derived genetic data and the subsequent secure storage of them. The set up of different kinds of clinical trials having in addition a genetic part, the concept of a genetic informed consent as well as collection schemes of samples are described in detail. Technical requirements and aspects of data protection including pseudonymization and anonymization procedures taking into account ethics committees requirements as well as the underlying legal framework are also presented. Without any exception, all principles and methods presented are best practices, repeatedly applied in different clinical environments and by no means theoretical considerations.

Foundations of Clinical Research

Foundations of Clinical Research Book
Author : Leslie G. Portney
Publisher :
Release : 2020
ISBN : 9780803661134
Language : En, Es, Fr & De

GET BOOK

Book Description :

"The text of this fourth edition has maintained its dual perspectives. It is designed for those who do research to generate new knowledge and examine theories and for those who want to be critical consumers of evidence to inform clinical decision-making. All of us need to be able to critically evaluate research reports to inform practice and further study. The scope of the text allows it to fulfill different needs at different times. This edition will continue to serve this wide audience. It incorporates several important contemporary themes, including the application of evidence-based practice (EBP) for clinical decision-making, the imperative of interprofessional collaboration, the implications of translational research, and the focus of healthcare on quality of life, meaningful outcomes, and patient values. These directions and priorities continue to define research philosophies that guide the conduct of clinical inquiry, the types of questions that are deemed important, and how they influence advances in measurement and analysis techniques"--

Clinical Research in Complementary Therapies E Book

Clinical Research in Complementary Therapies E Book Book
Author : George Thomas Lewith,Wayne B. Jonas,Harald Walach
Publisher : Elsevier Health Sciences
Release : 2010-11-23
ISBN : 0702049166
Language : En, Es, Fr & De

GET BOOK

Book Description :

The use of complementary therapies is exploding, increasing the pressure to establish a rigorous science to support its practice. Clinical Research in Complementary Therapies: Principles, Problems and Solutions provides students with the tools they need to research complementary and integrative medicine (CIM) and so fill this gap. Essential for both undergraduate and postgraduate students, this second edition is significantly updated and enhanced. Part 1 deals with research strategies and methods, explaining the major types of clinical research in CIM and how these inter-relate. New chapters are included on whole systems research, qualitative research and questionnaire development. Not all therapies can be treated the same way nor channeled through the signal process of randomized controlled trials. Therefore, detailed description of mixed methods approaches including observational, qualitative, cost-benefit and comparative effectiveness research are described. Part 2 deals with specific complementary therapies and how they are invested by experts in each field. The book analyses the key questions asked and the controversies debated in complementary medicine research and offers clear and innovative guidance for answering these questions. FEATURES • Provides an overarching synthesis of methods in CIM and how they are to be used collectively including the role of comparative effectiveness research • Suggests both general and specific factors which need to be considered in assessing or planning complementary therapy research • Pinpoints aspects of research which are different in orthodox research and complementary therapy research • Reviews the types of research carried out in specific complementary therapies and analyses issues which arise • Includes information on measuring the economic cost and benefits of complementary medicine, clinical audit and the role of placebos use • Builds upon recent research results, looks at the lessons these provide for all complementary therapies and suggests key issues to address in future research. • Provides an overarching synthesis of methods in CIM and how they are to be used collectively including the role of comparative effectiveness research • Suggests both general and specific factors which need to be considered in assessing or planning complementary therapy research • Pinpoints aspects of research which are different in orthodox research and complementary therapy research • Reviews the types of research carried out in specific complementary therapies and analyses issues which arise • Includes information on measuring the economic cost and benefits of complementary medicine, clinical audit and the role of placebos use • Builds upon recent research results, looks at the lessons these provide for all complementary therapies and suggests key issues to address in future research.