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Postmortem Toxicology

Postmortem Toxicology Book
Author : Timothy P. Rohrig
Publisher : Academic Press
Release : 2019-02-22
ISBN : 0128151641
Language : En, Es, Fr & De

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Book Description :

Postmortem Toxicology addresses the various aspects of the practice of forensic postmortem toxicology from a viewpoint of elements which must be taken into consideration for proper interpretation of the toxicological result, not in a vacuum but in a more holistic and global sense. The volume examines pre-analytical factors, storage containers/conditions, prior medical interventions and therapy, along with information from the scene investigation and anatomical findings. This reference also provides explanation of the complicating conditions for the interpretation of the toxicological results due to postmortem decomposition, embalming artifacts and the postmortem redistribution of drugs. Tolerance is also discussed as an aid to interpreting results from a habitual/chronic user of medications and/or drugs of abuse. The book is geared towards the current practitioner; however, it is written to be used as a valuable reference for a graduate or post-graduate level courses in forensic toxicology or forensic pathology. Presents a holistic approach to the interpretation of toxicology results Covers pre-analytical factors, storage containers/conditions, prior medical interventions, therapy, and much more Written for the current practitioner, but an excellent resource for graduate level students training in the field of forensic toxicology

Postmortem Toxicology of Abused Drugs

Postmortem Toxicology of Abused Drugs Book
Author : Steven B. Karch, MD, FFFLM
Publisher : CRC Press
Release : 2007-10-09
ISBN : 9781420054545
Language : En, Es, Fr & De

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Book Description :

Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you need at an affordable price. Postmortem Toxicology of Abused Drugs considers the role of toxicology in the investigation of homicide, suicide, accident, natural death, and overdose. It gives practical insights and case reviews on conducting toxicology tests and completing toxicology reports. It explains chain of custody; specimen collection and security; sampling of blood, urine, bile, and vitreous humor; and the selection of post-mortem specimens. Analyzing various testing procedures, the book covers simple chemical tests, microdiffusion tests, chromatography, spectroscopy, and more. It also discusses methods and strategies for analysis; and covers quality assurance protocols and controls. To help avoid common pitfalls, the text demonstrates the proper interpretation of postmortem drug levels based on knowledge of pharmacokinetics, metabolism, and pharmacogenetics; post-mortem redistribution and diffusion; and other considerations such as synergistic toxicity, and drug instability. Heavily referenced and containing several tables, figures, and useful appendices, this book is a handy reference for forensic scientists and medical examiners involved with death investigation.

Forensic Microbiology

Forensic Microbiology Book
Author : David O. Carter,Jeffery K. Tomberlin,M. Eric Benbow,Jessica L. Metcalf
Publisher : John Wiley & Sons
Release : 2017-03-27
ISBN : 1119062578
Language : En, Es, Fr & De

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Book Description :

Forensic Microbiology focuses on newly emerging areas of microbiology relevant to medicolegal and criminal investigations: postmortem changes, establishing cause of death, estimating postmortem interval, and trace evidence analysis. Recent developments in sequencing technology allow researchers, and potentially practitioners, to examine microbial communities at unprecedented resolution and in multidisciplinary contexts. This detailed study of microbes facilitates the development of new forensic tools that use the structure and function of microbial communities as physical evidence. Chapters cover: Experiment design Data analysis Sample preservation The influence of microbes on results from autopsy, toxicology, and histology Decomposition ecology Trace evidence This diverse, rapidly evolving field of study has the potential to provide high quality microbial evidence which can be replicated across laboratories, providing spatial and temporal evidence which could be crucial in a broad range of investigative contexts. This book is intended as a resource for students, microbiologists, investigators, pathologists, and other forensic science professionals.

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology Book
Author : Robert J. Flanagan
Publisher : John Wiley & Sons
Release : 2007
ISBN : 0470319348
Language : En, Es, Fr & De

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Book Description :

The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electro­phoresis, mass spectrometry, and immunoassay ? are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: ?This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.? Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists ?Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background ?Boxes?. The many and up to date literature references in each chapter demonstrate the authors? thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.? GTFCh Bulletin ?Toxichem + Krimtech?, May 2008 (translated, original review in German) ?Many toxicologists will add this important reference to their libraries because it competently fills a need ...? International Journal of Toxicology ?The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.? International Journal of Environmental Analytical Chemistry

Forensic Toxicology

Forensic Toxicology Book
Author : Max M. Houck
Publisher : Academic Press
Release : 2018-01-02
ISBN : 0128008180
Language : En, Es, Fr & De

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Book Description :

Forensic Toxicology, the latest release in the Advanced Forensic Science Series that grew out of recommendations from the 2009 NAS Report, Strengthening Forensic Science: A Path Forward will serve as a graduate level text for those studying and teaching forensic toxicology. It is also an excellent reference for the forensic practitioner’s library or for use in their casework. Coverage includes a wide variety of methods used, along with pharmacology and drugs and professional issues they may encounter. Edited by a world-renowned, leading forensic expert, this updated edition is a long overdue solution for the forensic science community. Provides basic principles of forensic science and an overview of forensic toxicology Contains information on a wide variety of methods Covers pharmacology and drugs, matrices and interpretation Includes a section on professional issues, such as crime scene to court, lab reports, health and safety, post-mortem and drug facilitated crimes Incorporates effective pedagogy, key terms, review questions, discussion questions and additional reading suggestions

Principles of Forensic Toxicology

Principles of Forensic Toxicology Book
Author : Barry Levine
Publisher : Amer. Assoc. for Clinical Chemistry
Release : 2003
ISBN : 9781890883874
Language : En, Es, Fr & De

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Book Description :

Download Principles of Forensic Toxicology book written by Barry Levine, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Forensic Toxicology

Forensic Toxicology Book
Author : Robert H. Powers,Dorothy E. Dean
Publisher : CRC Press
Release : 2015-12-01
ISBN : 1466581956
Language : En, Es, Fr & De

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Book Description :

Designed for upper-level undergraduate and graduate-level courses, Forensic Toxicology: Mechanisms and Pathology introduces toxicology concepts from a forensic perspective. The book provides an understanding of the mechanistic basis of the action of drugs and toxins, addressing their physiologic and pathologic consequences on the affected organ sys

Clarke s Analytical Forensic Toxicology

Clarke s Analytical Forensic Toxicology Book
Author : Gail Cooper,Adam Negrusz
Publisher : Pharmaceutical Press
Release : 2013-05-28
ISBN : 0857110543
Language : En, Es, Fr & De

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Book Description :

This second edition of Clarke's Analytical Forensic Toxicology offers a fresh perspective on the drugs and poisons that you are most likely to encounter in forensic toxicology, with a focus on collection, extraction and analysis. With additional features incorporated from the fourth edition of Clarke's Analysis of Drugs and Poisons this text is fully updated to reflect the advances in analytical and forensic toxicology. New and extended chapters include: sampling, storage and stability; in-utero exposure to drugs of abuse; drug-facilitated sexual assault; and extraction. Providing unrivalled comprehensive coverage of analytical forensic toxicology, this book is a crucial resource for students of forensic science, toxicology, clinical pharmacology and analytical chemistry. It is an invaluable tool for teachers in these subject areas and a key resource for those working in forensic science laboratories.

Drug Abuse Handbook Second Edition

Drug Abuse Handbook  Second Edition Book
Author : Steven B. Karch, MD, FFFLM
Publisher : CRC Press
Release : 2006-12-21
ISBN : 1420003461
Language : En, Es, Fr & De

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Book Description :

Following the well-received first edition, the Drug Abuse Handbook, Second Edition is a thorough compendium of the knowledge of the pharmacological, medical, and legal aspects of drugs. The book examines criminalistics, pathology, pharmacokinetics, neurochemistry, treatment, as well as drugs and drug testing in the workplace and in sports, and the ethical, legal, and practical issues involved. Dr. Karch gathers contributions from 80 leading experts in their respective fields to update and revise this second edition with more than 40 percent new material. New topics include genetic testing in drug death investigation, the neurochemistry of nicotine and designer amphetamines, genetic doping in sports, and the implications of the Daubert ruling on the admissibility of scientific evidence in federal court. Packed with the latest information in an easily accessible format, the book includes tables of all Scheduled Drugs, methods of Drug Quantitative Analysis, and a glossary of forensic toxicology terms. Vivid pictures and diagrams illustrate the pathological effects of drugs and the chemical make-up and breakdown of abused drugs. It includes more than 6000 references to the best sources in medicine, pharmacology, and the law. This book addresses specific problems in drug testing, drug-related medical emergencies, and the physical, neurochemical, and sociological phenomenon of addiction. With unparalleled detail and the highest level of authoritative information, The Drug Abuse Handbook, Second Edition is the definitive resource for drug related issues.

Distribution of Methadone and EDDP in Postmortem Toxicology Cases

Distribution of Methadone and EDDP in Postmortem Toxicology Cases Book
Author : Jessica Amanda Jennings
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Distribution of Methadone and EDDP in Postmortem Toxicology Cases book written by Jessica Amanda Jennings, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Necropsy Guide for Dogs Cats and Small Mammals

Necropsy Guide for Dogs  Cats  and Small Mammals Book
Author : Sean P. McDonough,Teresa Southard
Publisher : John Wiley & Sons
Release : 2017-02-06
ISBN : 1119115655
Language : En, Es, Fr & De

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Book Description :

Necropsy Guide for Dogs, Cats, and Small Mammals is a complete, practical resource for performing necropsies on dogs, cats, rabbits, rodents, and ferrets in the veterinary clinic, animal shelter, research laboratory, or in the field. Provides practical guidance on all aspects of performing an necropsy on dogs, cats, and small mammals and interpreting the results Presents more than 200 full-color images to demonstrate techniques and findings Offers step-by-step instructions for the necropsy process and collecting samples Includes an anatomy review, discussion of dissection techniques, and list of common artifacts and post-mortem changes for each organ system Supports veterinarians in performing a necropsy in any setting, including animal shelters, veterinary clinics, research laboratories, and in the field

Forensic Toxicology

Forensic Toxicology Book
Author : Nicholas T. Lappas,Courtney M. Lappas
Publisher : Academic Press
Release : 2021-10-22
ISBN : 0128192879
Language : En, Es, Fr & De

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Book Description :

The second edition of Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, principles of forensic toxicology including pharmacokinetics, pharmacodynamics, drug interactions and toxicogenomics, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Also included in the second edition is a Unit focused on the forensic toxicology of individual drugs of abuse. Includes significant emphasis on the fundamental principles and concepts of forensic toxicology Provides students with an introduction to the core tenets of the discipline, focusing on the concepts, strategies, and methodologies utilized by professionals in the field Coauthored by a forensic toxicologist with over 40 years of experience as a professor who has taught graduate courses in forensic and analytical toxicology and who has served as a consultant and expert witness in civil and criminal cases

Forensic Toxicology

Forensic Toxicology Book
Author : Susannah Davies,Atholl Johnston,David Holt
Publisher : Royal Society of Chemistry
Release : 2019-03-15
ISBN : 1788018109
Language : En, Es, Fr & De

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Book Description :

New designer drugs, access to databases, and changing availability of samples for analysis have changed the face of modern forensic toxicology in recent years. Forensic Toxicology: Drug Use and Misuse brings together the latest information direct from experts in each sub-field of the discipline providing a broad overview of current thinking and the most innovative approaches to case studies. The text begins with an in-depth discussion of pharmaco­epidemiology, including information on the value of nationwide databases in forensic toxicology. The use and abuse of drugs in driving, sport and the workplace are then discussed by industry experts who are conducting case work in their field. Not only are new drug groups discussed (NPS), but also their constantly changing impact on drug legislation. Synthetic cannabinoids, khat and mephodrone are discussed in detail. Following a section devoted to legislation and defence, readers will find comprehensive chapters covering sample choice reflecting the increasing use of hair and oral fluid, and also the less commonly used sweat and nail analysis. New and old case examples are compared and contrasted in the final part of the book, which will enable readers to understand how drugs impact on each other and how the interpretative outcome of a case are dependent on many aspects. From use of pharmaceutical drugs in a clinical setting, through smart drugs to new psychoactive drugs, this book documents the wide range in which drugs today are abused. This book will be an essential resource for postgraduate students in forensic toxicology, and for researchers in forensic toxicology laboratories who need the latest data and knowledge.

Issues in Radiation Biology and Toxicology Research 2013 Edition

Issues in Radiation Biology and Toxicology Research  2013 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2013-05-01
ISBN : 1490110666
Language : En, Es, Fr & De

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Book Description :

Issues in Radiation Biology and Toxicology Research: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Analytical Toxicology. The editors have built Issues in Radiation Biology and Toxicology Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Analytical Toxicology in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Radiation Biology and Toxicology Research: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Encyclopedia of Toxicology

Encyclopedia of Toxicology Book
Author : Bruce Anderson,Ann de Peyster,Shayne C. Gad,P.J. Bert Hakkinen,Michael Kamrin,Betty Locey,Harihara M. Mehendale,Carey Pope,Lee Shugart
Publisher : Elsevier
Release : 2005-05-31
ISBN : 0080548008
Language : En, Es, Fr & De

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Book Description :

The second edition of the Encyclopedia of Toxicology continues its comprehensive survey of toxicology. This new edition continues to present entries devoted to key concepts and specific chemicals. There has been an increase in entries devoted to international organizations and well-known toxic-related incidents such as Love Canal and Chernobyl. Along with the traditional scientifically based entries, new articles focus on the societal implications of toxicological knowledge including environmental crimes, chemical and biological warfare in ancient times, and a history of the U.S. environmental movement. With more than 1150 entries, this second edition has been expanded in length, breadth and depth, and provides an extensive overview of the many facets of toxicology. Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. *Second edition has been expanded to 4 volumes *Encyclopedic A-Z arrangement of chemicals and all core areas of the science of toxicology *Covers related areas such as organizations, toxic accidents, historical and social issues, and laws *New topics covered include computational toxicology, cancer potency factors, chemical accidents, non-lethal chemical weapons, drugs of abuse, and consumer products and many more!

Toxicology Testing An Issue of Clinics in Laboratory Medicine E Book

Toxicology Testing  An Issue of Clinics in Laboratory Medicine   E Book Book
Author : Michael G. Bissell
Publisher : Elsevier Health Sciences
Release : 2012-09-24
ISBN : 1455747874
Language : En, Es, Fr & De

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Book Description :

This issue of Clinics in Laboratory Medicine, titled Toxicology Testing, includes the following topics; Progress in Clinical Toxicology Testing, The Prescription Drug Abuse Epidemic, Substance Abuse Among Healthcare Professionals, Pain Management Drug Testing, Ethanol Biomarkers, Newly-emerging Drugs of Abuse, Synthetic Cannabinoids, Synthetic Cathenones, Immunoassay Methodology in Drugs-of-abuse Testing, Toxicology Testing in Alternative Specimen Matrices, Principles and Procedures in Postmortem Toxicology, and Pharmacogenetics and the Future of Toxicology Testing. Advances in toxicology testing are paving the way for major improvements in the way scientists evaluate health risks posed by toxic chemicals. Toxicity tests help scientists better understand how the human body carries out normal functions that are key to maintaining health. Therefore, this topic is important to the field of Laboratory Medicine.

Information Resources in Toxicology

Information Resources in Toxicology Book
Author : P.J. Bert Hakkinen,Asish Mohapatra,Steven G. G. Gilbert
Publisher : Academic Press
Release : 2009-08-19
ISBN : 9780080920030
Language : En, Es, Fr & De

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Book Description :

This latest version of Information Resources in Toxicology (IRT) continues a tradition established in 1982 with the publication of the first edition in presenting an extensive itemization, review, and commentary on the information infrastructure of the field. This book is a unique wide-ranging, international, annotated bibliography and compendium of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. Thoroughly updated, the current edition analyzes technological changes and is rife with online tools and links to Web sites. IRT-IV is highly structured, providing easy access to its information. Among the “hot topics covered are Disaster Preparedness and Management, Nanotechnology, Omics, the Precautionary Principle, Risk Assessment, and Biological, Chemical and Radioactive Terrorism and Warfare are among the designated. • International in scope, with contributions from over 30 countries • Numerous key references and relevant Web links • Concise narratives about toxicologic sub-disciplines • Valuable appendices such as the IUPAC Glossary of Terms in Toxicology • Authored by experts in their respective sub-disciplines within toxicology

Issues in Radiation Biology and Toxicology Research 2011 Edition

Issues in Radiation Biology and Toxicology Research  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464965781
Language : En, Es, Fr & De

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Book Description :

Issues in Radiation Biology and Toxicology Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Radiation Biology and Toxicology Research. The editors have built Issues in Radiation Biology and Toxicology Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Radiation Biology and Toxicology Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Radiation Biology and Toxicology Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Information Resources in Toxicology

Information Resources in Toxicology Book
Author : Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes
Publisher : Academic Press
Release : 2020-05-16
ISBN : 0128137258
Language : En, Es, Fr & De

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Book Description :

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources. Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles. Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals. Explores recent internet trends, web-based databases, and software tools in a section on the online environment. Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents. Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field.

The Challenge Posed by New Synthetic Opioids Pharmacology and Toxicology

The Challenge Posed by New Synthetic Opioids  Pharmacology and Toxicology Book
Author : Simona Pichini,Francesco Paolo Busardò
Publisher : Frontiers Media SA
Release : 2019-08-19
ISBN : 2889459721
Language : En, Es, Fr & De

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Book Description :

New Synthetic Opioids (NSOs), most of which are illegally produced and sold for recreational use, are posing a serious threat to the health of consumers. Due to the low cost of materials and equipment required for clandestine laboratories production with respect to the production cost of heroin, NSOs are climbing the illegal street and web drug market. Several of these drugs have been involved in a recent rise in acute intoxications and overdose deaths. Since NSOs offer enormous profit potential, and there is strong demand for their use, these drugs are being trafficked by organized crime and present major challenges for medical professionals facing intoxications and fatalities, law enforcement agencies fighting against their diffusion and policymakers trying to restrain the use and abuse of NSOs. This Research Topic aimed to fill the gap on current knowledge on pharmacology and toxicology, health risks for adult and newborns of NSOs covering both basic scientific as well as epidemiological and clinical aspects. 3 reviews, 3 mini-reviews, 1 original article, 2 case reports and 1 opinion are here presented.