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Polysaccharide Carriers For Drug Delivery

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Polysaccharide Carriers for Drug Delivery

Polysaccharide Carriers for Drug Delivery Book
Author : Sabyasachi Maiti,Sougata Jana
Publisher : Woodhead Publishing
Release : 2019-06-14
ISBN : 0081025548
Language : En, Es, Fr & De

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Book Description :

Polysaccharide Carriers for Drug Delivery presents the latest information on the selection of safe materials. Due to reported safety profiles on polysaccharides; they have been the natural choice for investigation. A wide variety of drug delivery and biomedical systems have been studied, however, the related information either concept-wise or application-oriented is scattered, therefore becoming difficult for readers and researchers to digest in a concise manner. This gathering of information will help readers easily comprehend the subject matter. Focuses on biopolysaccharide-based, distinct approaches for drug delivery applications Illustrates new concepts and highlights future scope for clinical development Provides comprehensive, up-to-date information on different aspects of drug delivery technology

Polysaccharide based Nano Biocarrier in Drug Delivery

Polysaccharide based Nano Biocarrier in Drug Delivery Book
Author : Tapan Kumar Giri,Bijaya Ghosh
Publisher : CRC Press
Release : 2018-09-03
ISBN : 042983067X
Language : En, Es, Fr & De

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Book Description :

This book discusses various fundamental aspects of polysaccharide based nano-biocarrier drug delivery systems and its application in the delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment of cancer, cardiovascular, pulmonary, and infectious diseases.

Alginates in Drug Delivery

Alginates in Drug Delivery Book
Author : Amit Kumar Nayak,Md Saquib Hasnain
Publisher : Academic Press
Release : 2020-07-23
ISBN : 0128176415
Language : En, Es, Fr & De

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Book Description :

Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and in the biotechnology industry. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers’ biocompatibility, biodegradability, economic extraction and ready availability. To fully utilize and harness the potential of alginates, this book presents a thorough understanding of the synthesis, purification, and characterization of alginates and their derivative. This book collects, in a single volume, all relevant information on alginates in health care, including recent advances in the field. This is a highly useful resource for pharmaceutical scientists, health care professionals and regulatory scientists actively involved in the pharmaceutical product and process development of natural polymer containing drug delivery, as well as postgraduate students and postdoctoral research fellows in pharmaceutical sciences. Provides a single source on the complete alginate chemistry, collection, chemical modifications, characterization and applications in healthcare fields Includes high quality illustrations, along with practical examples and research case studies Contains contributions by global leaders and experts from academia, industry and regulatory agencies who are pioneers in the application of natural polysaccharides in diverse pharmaceutical fields

Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery

Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery Book
Author : Amit Kumar Nayak
Publisher : Springer Nature
Release : 2021-12-03
ISBN : 981162271X
Language : En, Es, Fr & De

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Book Description :

Download Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery book written by Amit Kumar Nayak, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Advances and Challenges in Pharmaceutical Technology

Advances and Challenges in Pharmaceutical Technology Book
Author : Amit Kumar Nayak,Kunal Pal,Indranil Banerjee,Samarendra Maji,Upendranath Nanda
Publisher : Academic Press
Release : 2021-02-09
ISBN : 0128203005
Language : En, Es, Fr & De

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Book Description :

Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines recent advancements in pharmaceutical technology. The book discusses common formulation strategies, including the use of tools for statistical formulation optimization, Quality by design (QbD), process analytical technology, and the uses of various pharmaceutical biomaterials, including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. In addition, the book covers rapid advancements in the field by providing a thorough understanding of pharmaceutical processes, formulation developments, explorations, and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms. Provides extensive information and analysis on recent advancements in the field of pharmaceutical technology Includes contributions from global leaders and experts in academia, industry and regulatory agencies Uses high quality illustrations, flow charts and tables to explain concepts and text to readers, along with practical examples and research case studies

Chitosan in Drug Delivery

Chitosan in Drug Delivery Book
Author : Md Saquib Hasnain,Sarwar Beg,Amit Kumar Nayak
Publisher : Academic Press
Release : 2021-10-26
ISBN : 0128193379
Language : En, Es, Fr & De

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Book Description :

Chitosan in Drug Delivery provides thorough insights into chitosan chemistry, collection, chemical modifications, characterization and applications in the pharmaceutical industry and healthcare fields. The book explores molecular weight, degree of deacetylation and molecular geometry, emphasizing recent advances in the field as written by academic, industry and regulatory scientists. It will be a useful resource for pharmaceutical scientists, including industrial pharmacists, analytical scientists, postgraduate students, health care professionals and regulatory scientists actively involved in pharmaceutical product and process development in natural polymers containing drug delivery. Provides methodologies for the design, development and selection of chitosan in drug delivery for particular therapeutic applications Includes illustrations demonstrating the mechanism of biological interaction of chitosan Discusses the regulatory aspects and demonstrates the clinical efficacy of chitosan

Tailor Made Polysaccharides in Biomedical Applications

Tailor Made Polysaccharides in Biomedical Applications Book
Author : Amit Kumar Nayak,Md Saquib Hasnain,Tejraj M. Aminabhavi
Publisher : Academic Press
Release : 2021-02-15
ISBN : 0128213566
Language : En, Es, Fr & De

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Book Description :

Tailor-Made Polysaccharides in Biomedical Applications provides extensive details on all the vital precepts, basics, and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industries. This information provides readers with the foundation for understanding and developing high-quality products. The utilization of natural polymeric excipients in numerous healthcare applications demands the replacement of the synthetic polymers with natural polymers. Natural polymers are superior in terms of biocompatibility, biodegradability, economic extraction, and ready availability. Natural polymers are especially useful in that they are a renewable source of raw materials, as long as they are grown sustainably. Among these natural polymers, polysaccharides are considered as excellent excipients because they are nontoxic, stable, and biodegradable. Several research innovations have been carried out using polysaccharides in drug delivery applications. This book offers a comprehensive resource to understand the potential of these materials in forming new drug delivery methods. It will be useful to biomedical researchers, chemical engineers, regulatory scientists, and students who are actively involved in developing pharmaceutical products for biomedical applications by using tailor-made polysaccharides. Provides methodology for the design, development, and selection of tailor-made polysaccharides in biomedical applications, including for particular therapeutic applications Includes illustrations demonstrating the mechanism of biological interaction of tailor-made polysaccharides Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides

Modeling and Control of Drug Delivery Systems

Modeling and Control of Drug Delivery Systems Book
Author : Ahmad Taher Azar
Publisher : Academic Press
Release : 2021-02-06
ISBN : 0128211954
Language : En, Es, Fr & De

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Book Description :

Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy. Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS

Biomedical Composites

Biomedical Composites Book
Author : Amit Kumar Nayak
Publisher : Springer Nature
Release : 2021-12-03
ISBN : 9813347538
Language : En, Es, Fr & De

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Book Description :

Download Biomedical Composites book written by Amit Kumar Nayak, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Synthesis of Carboxymethyl Cellulose CMC based Bionanogels for Dual Stimuli responsive Drug Release and Cancer Therapy

Synthesis of Carboxymethyl Cellulose  CMC  based Bionanogels for Dual Stimuli responsive Drug Release and Cancer Therapy Book
Author : Yifen Wen
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Polysaccharides possess great potential as building blocks in the development of drug delivery vehicles. This can be attributed to their outstanding virtues, such as biocompatibility,biodegradability, and possession of a plenty of functional groups. Their chemical flexibility allows for the modification of polysaccharides, leading to diverse functionalities that are valuable in biomedical applications. A promising functionality is stimuli-responsiveness that results in a change of physical or chemical properties of polysaccharide-based nanocarriers in response to an environmental change, such as pH, temperature, and light. Herein, recent strategies to develop polysaccharide-based nanomaterials for biomedical application are mapped out. Furthermore, using carboxymethyl cellulose (CMC) as a promising pH-sensitive polysaccharide, two types of stimuli-responsive polysaccharide-based nanomaterials were developed and evaluated as potential tumor targeting drug delivery nanocarriers. The first system involves dual pH/reduction responsive polysaccharide-based bionanogels(ssBNGs) prepared by aqueous crosslinking polymerization. CMC is grafted with pendant oligo(ethylene oxide) containing methacrylate (OEOMA), and crosslinked with a disulfidelabeled dimethacrylate, yielding disulfide crosslinked ssBNGs with a diameter ≈ 24 nm measured by dynamic light scattering. ssBNGs exhibit dual pH/reduction-responsive drug release, attributed to less interactions between the encapsulated drug molecules and CMC at acidic pH and the reductive cleavage of disulfide crosslinkers. The possibility of conjugating a targeting ligand to ssBNGs is confirmed with a model water-soluble UV-active dye. The second system includes dual pH/temperature responsive bionanogels (DuR-BNGs). Thermoresponsive polymers undergo volume change above their lower critical solution temperature (LCST) due to a hydrophilic/hydrophobic transition. DuR-BNGs were prepared by grafting thermoresponsive monomers: di(ethylene oxide) methyl ether methacrylate (MEO2MA) and OEOMA from CMC in the presence of crosslinker via aqueous crosslinking polymerization. The self-association of grafted P(MEO2MA-co-OEOMA) above their LCST resulted in a micelle-like structure of DuR-BNGs as well as narrow size distribution. DuR-BNGs exhibit pH responsive drug release due to the pH-dependent interaction of CMC with drug molecules. The temperature-responsive drug release was driven by the shrinkage of DuR-BNGs networks upon high temperature treatment, thereby expelling encapsulated cargoes causing rapid drug release. The non-specific protein absorption of DuR-BNGs is evaluated with bovine serum albumin (BSA) as a model. The potential application of two types of dual stimuli-responsive bionanogels (BNGs) in drug delivery is demonstrated with cell viability by MTT assay and cellular uptake using confocal laser scanning microscopy and flow cytometry.

Food Medical and Environmental Applications of Polysaccharides

Food  Medical  and Environmental Applications of Polysaccharides Book
Author : Kunal Pal,Indranil Banerjee,Preetam Sarkar,Arindam Bit,Doman Kim,Arfat Anis,Samarendra Maji
Publisher : Elsevier
Release : 2020-12-03
ISBN : 0128193131
Language : En, Es, Fr & De

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Book Description :

Food, Medical, and Environmental Applications of Polysaccharides provides a detailed resource for those interested in the design and preparation of polysaccharides for state-of-the-art applications. The book begins with an introductory section covering sources, chemistry, architectures, bioactivity, and chemical modifications of polysaccharides. Subsequent parts of the book are organized by field, with chapters focusing on specific applications across food, medicine, and the environment. This is an extremely valuable book for researchers, scientists, and advanced students in biopolymers, polymer science, polymer chemistry, biomaterials, materials science, biotechnology, biomedical engineering, cosmetics, medicine, food science, and environmental science. This important class of biopolymer can offer attractive properties and modification potential, enabling its use in groundbreaking areas across food, medical, and environmental fields. The book will be of interest to scientists, R&D professionals, designers, and engineers who utilize polysaccharide-based materials. Presents comprehensive information of the polymeric structures and properties that can be developed from polysaccharides Offers systematic coverage of classification, synthesis, and characterization, enabling targeted design and preparation of polysaccharides for specific applications Explores advanced methods, for novel applications across food, medicine, and the environment

Polysaccharides in Advanced Drug Delivery

Polysaccharides in Advanced Drug Delivery Book
Author : Akhilesh Vikram Singh,Bang-Jing Li
Publisher : CRC Press
Release : 2020-03-24
ISBN : 1000050866
Language : En, Es, Fr & De

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Book Description :

This book contains selective chapters from eminent experts working in the interdisciplinary arena of material science and its use in drug delivery. From their recent research experience, the readers can achieve a wide vision on the new and ongoing potentialities of polysaccharides and its application in the field of advanced drug delivery. This book contains selective polymers that were recently explored in the field of drug delivery such as starch, konjac, chitosan, alginate and other natural polymers originated from sea. It also has one chapter exclusively on nanotechnology that explains multifaceted application of natural polymer in the field of advanced drug delivery. Note: T& F does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.

Carbon Nanotubes for Targeted Drug Delivery

Carbon Nanotubes for Targeted Drug Delivery Book
Author : Md Saquib Hasnain,Amit Kumar Nayak
Publisher : Springer Nature
Release : 2019-11-08
ISBN : 9811509107
Language : En, Es, Fr & De

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Book Description :

This book provides a detailed introduction to carbon nanotubes (CNTs) for targeted drug delivery. After a brief overview of the classification, preparation, and characterization of carbon nanotubes, it focuses on their use in targeted drug delivery. It presents CNTs for brain targeting, ocular targeting, cancer targeting, and lymphatic targeting, as well as antibody therapy. The book also includes chapters on carbon nanotubes for controlled drug delivery, transdermal drug delivery, solubility enhancement, vaccine delivery, gene delivery, and as quantum dots. Last but not least, it addresses the absorption and transportation of CNTs, toxicity and regulatory considerations, as well as clinical trials and the market status of CNTs. The book offers a comprehensive, self-contained reference guide, with all topics covered concisely and with the help of figures, tables and flowcharts.

Microbial Exopolysaccharides as Novel and Significant Biomaterials

Microbial Exopolysaccharides as Novel and Significant Biomaterials Book
Author : Ashok Kumar Nadda,Sajna K. V.,Swati Sharma
Publisher : Springer Nature
Release : 2021
ISBN : 3030752895
Language : En, Es, Fr & De

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Book Description :

This book examines the commercial role of various microbial polysaccharides and recent advances in their production. Offering an overview of the physiological role, biosynthetic pathways and regulatory mechanisms, it also explores the current challenges regarding bioprocessing for the production of polysaccharides.

Nanomaterials in Energy and Environmental Applications

Nanomaterials in Energy and Environmental Applications Book
Author : Junhui He
Publisher : CRC Press
Release : 2016-10-14
ISBN : 1315341298
Language : En, Es, Fr & De

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Book Description :

Nanoscience and nanotechnology are interdisciplinary fields that bring together physicists, chemists, materials scientists, and engineers to meet the potential future challenges that humankind will face, including the search for renewable energies for sustainable development and new technologies for carbon capture and environmental protection. Among the current subjects in nanoscience and nanotechnology, nanomaterials are developing fast and explosively and attracting a huge amount of attention. They continue to show promising potential and have found application in solar cells, fuel cells, secondary batteries, supercapacitors, air and water purification, and removal of domestic and outdoor air pollutants. To summarize the past developments and encourage future efforts, this book presents contributions from world-renowned specialists in the fields of nanomaterials, energy, and environmental science. It discusses the design and fabrication of nanostructured materials and their energy and environmental applications.

Polysaccharides

Polysaccharides Book
Author : Mohd Imran Ahamed,Inamuddin,Rajender Boddula,Tariq A. Altalhi
Publisher : John Wiley & Sons
Release : 2021-05-25
ISBN : 1119711401
Language : En, Es, Fr & De

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Book Description :

In diesem Werk werden Polysaccharide unter sämtlichen Aspekten betrachtet, von den Grundkonzepten bis zur kommerziellen Vermarktung. Thema der einzelnen Kapitel sind die verschiedenen Arten von Quellen, die Klassifikation, Eigenschaften, Charakterisierung, Verarbeitung, Rheologie und Herstellung von Materialien auf Grundlage von Polysacchariden sowie von Polysaccharid-Gemischen und -Gelen. Anwendung finden Polysaccharide u. a. in der Kosmetik, der Lebensmittelwissenschaft, der Medikamentenverabreichung, der Biomedizin, der Biokraftstoffproduktion, der Schifffahrt, im Verpackungswesen, in der Chromatographie und der Umweltsanierung. Darüber hinaus vermittelt das Werk einen Überblick über die Herstellung von anorganischen und Kohlenstoff-Nanomaterialien aus Polysacchariden. Mit der Betrachtung industrieller Anwendungen schließt das Buch die Lücke zwischen der Forschungsarbeit im Labor und wirtschaftlich nutzbaren Anwendungen in entsprechenden Unternehmen.

Chitosan in Biomedical Applications

Chitosan in Biomedical Applications Book
Author : Md Saquib Hasnain,Sarwar Beg,Amit Kumar Nayak
Publisher : Academic Press
Release : 2021-12-13
ISBN : 0128212446
Language : En, Es, Fr & De

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Book Description :

Chitosan in Biomedical Applications provides a thorough insight into the complete chitosan chemistry, collection, chemical modifications, characterization and applications of chitosan in biomedical applications and healthcare fields. Chitosan, a biopolymer of natural origin, has been explored for its variety of applications in biomedical research, medical diagnostic aids and material science. It is the second most abundant natural biopolymer after cellulose, and considered as an excellent excipient because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of chitosan in biomedical applications. The book explores key topics, such as molecular weight, degree of deacetylation, and molecular geometry, along with an emphasis on recent advances in the field written by academic, industry, and clinical researchers. Chitosan in Biomedical Applications will be of interest to those in biomedical fields including the biomaterials and tissue engineering community investigating and developing biomaterials for biomedical applications, particularly graduate students, young faculty and others exploring chitosan-based materials. Provides methodology for the design, development and selection of chitosan in biomedical applications for particular therapeutic applications Includes illustrations demonstrating the mechanism of biological interaction of chitosan Discusses the regulatory aspects and demonstrates the clinical efficacy of chitosan

Radiation Processed Polysaccharides

Radiation Processed Polysaccharides Book
Author : M. Naeem,Tariq Aftab,M. Masroor A. Khan
Publisher : Academic Press
Release : 2021-09-11
ISBN : 0323886094
Language : En, Es, Fr & De

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Book Description :

Radiation-Processed Polysaccharides: Emerging Roles in Agriculture is the first book to focus exclusively on this emerging and important option for reducing the overuse and negative impact of agrochemicals in agriculture. Among practices being developed for effective and eco-friendly plant growth regulators in crop production, using radiation-processed polysaccharides (RPPs) is a promising technique. Comprised of chapters from diverse areas of plant science, including agriculture, agronomy, biotechnology, nanotechnology, molecular biology, and radiation agriculture, this book provides insights into the practical application of RPPs and inspires further research toward sustainable and efficient agricultural production. Polysaccharides (sodium alginate, carrageenan, chitosan and others) in their depolymerized state are increasingly important to agriculture based on their unique biological properties, biocompatibility, biodegradability and non-toxicity. Understanding the impact of RPPs on the plant phenotype, translocation of nutrients from source to sink, signal processing, and crosstalk helps improve the applicability of RPPs and sustainable agricultural yield. Presents the latest application of RPPs for improved plant production Includes insights for abiotic stress, biotechnology, nanotechnology and molecular application Explores the efficiency of natural polysaccharides as plant growth promoters

Innovation in Nano polysaccharides for Eco sustainability

Innovation in Nano polysaccharides for Eco sustainability Book
Author : Preeti Singh,Kaiser Manzoor,Saiqa Ikram,Pratheep Kumar Annamalai
Publisher : Elsevier
Release : 2021-10-15
ISBN : 0128234458
Language : En, Es, Fr & De

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Book Description :

Innovation in Nano-polysaccharides for Eco-sustainability: From Science to Industrial Applications presents fundamentals, advanced preparation methods, and novel applications for polysaccharide-based nanomaterials. Sections cover the fundamental aspects of polysaccharides and nano-polysaccharides, including their structure and properties, surface modification, processing and characterization. Key considerations are explained in detail, including the connection between the substituents of polysaccharides and their resulting physical properties, renewable resources, their sustainable utilization, and specific high value applications, such as pharmaceuticals, photocatalysts, energy, and wastewater treatment, and more. This is a valuable resource for researchers, scientists, and advanced students across bio-based polymers, nanomaterials, polymer chemistry, sustainable materials, biology, materials science and engineering, and chemical engineering. In industry, this book will support scientists, R&D, and engineers looking to utilize bio-based materials in advanced industrial applications. Covers the fundamentals, mechanisms, preparation methods, unique properties and performance of nano-polysaccharide materials Explores sustainable applications of nano-polysaccharides in areas such as pharmaceuticals, energy and wastewater treatment Addresses key challenges, including the implementation of sustainable concepts in chemical design and paths to scalability and commercialization

Biological Activities and Application of Marine Polysaccharides

Biological Activities and Application of Marine Polysaccharides Book
Author : Emad Shalaby
Publisher : BoD – Books on Demand
Release : 2017-01-11
ISBN : 9535128590
Language : En, Es, Fr & De

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Book Description :

Marine organisms have been under research for the last decades as a source for different active compounds with various biological activities and application in agriculture, pharmacy, medicine, environment, and industries. Marine polysaccharides from these active compounds are used as antibacterial, antiviral, antioxidant, anti-inflammation, bioremediations, etc. During the last three decades, several important factors that control the production of phytoplankton polysaccharides have been identified such as chemical concentrations, temperature, light, etc. The current book includes 14 chapters contributed by experts around the world; the chapters are categorized into three sections: Marine Polysaccharides and Agriculture, Marine Polysaccharides and Biological Activities, and Marine Polysaccharides and Industries.