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Polyphenols Prevention And Treatment Of Human Disease

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Polyphenols in Human Health and Disease

Polyphenols in Human Health and Disease Book
Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Release : 2018-08-06
ISBN : 0128130091
Language : En, Es, Fr & De

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Book Description :

Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, obesity, diabetes and osteoporosis. This collection represents the contributions of an international group of experts in polyphenol research who share their expertise in endocrinology, public health, cardiology, pharmacology, agriculture and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted insights into the mechanisms of disease. This reference fills a void in research where nutritionists and alternative therapies may be applicable. Describes polyphenol modulation of blood flow and oxygenation as a potential mechanism of protection against vascular atherosclerosis Describes how polyphenols and antioxidants frequently change immune defenses and actions Focuses on the most important areas of research and provides insights into their relationships and translational opportunities

Polyphenols

Polyphenols Book
Author : Ronald Ross Watson,Victor R. Preedy
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Polyphenols book written by Ronald Ross Watson,Victor R. Preedy, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Polyphenols in Human Health and Disease

Polyphenols in Human Health and Disease Book
Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Release : 2013-10-26
ISBN : 012398467X
Language : En, Es, Fr & De

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Book Description :

Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. Explores neuronal protection by polyphenol metabolites and their application to medical care Defines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applications Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases

Polyphenols in Human Health and Disease

Polyphenols in Human Health and Disease Book
Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Release : 2018-08-06
ISBN : 0128130075
Language : En, Es, Fr & De

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Book Description :

Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. Expands coverage on green tea, cocoa, wine, cumin and herbs Outlines their chemical properties, bioavailability and metabolomics Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols

Encapsulation of Active Molecules and Their Delivery System

Encapsulation of Active Molecules and Their Delivery System Book
Author : Shirish Hari Sonawane,Bharat A. Bhanvase,Manickam Sivakumar
Publisher : Elsevier
Release : 2020-03-24
ISBN : 0128193646
Language : En, Es, Fr & De

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Book Description :

Encapsulation of Active Molecules and Their Delivery System covers the key methods of preparation of encapsulation, as well as release mechanisms and their applications in food, biotechnology, metal protection, drug delivery, and micronutrients delivery in agriculture. The book also provides real-life examples of applications in food and other industries. Sections encompasses (i) Synthesis and characterization methods of micro- and nanocarriers as the delivery systems, (ii) Up-to-date encapsulation techniques in the areas of pharmaceuticals, nutraceuticals and corrosion, (iii) The release methods of the encapsulated materials, and (iv) Industry perspectives, including scale up of the processes. Focuses on encapsulation processes in chemical and materials engineering and biotechnology Provides a relevant resource for the pharmaceutical and food industries Presents wide coverage on the entrapment of molecules that scales-up to industrial sized needs

Medicinal Natural Products A Disease Focused Approach

Medicinal Natural Products  A Disease Focused Approach Book
Author : Anonim
Publisher : Academic Press
Release : 2020-11-01
ISBN : 0128210206
Language : En, Es, Fr & De

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Book Description :

Medicinal Natural Products: A Disease-Focused Approach, Volume 55 in the Annual Reports in Medicinal Chemistry series, highlights the applications of natural products as medicines or prospective medicinal leads for the treatment of various human ailments. Each chapter covers a particular disease area or medical condition, with chapters in this new release covering Medicinal Natural Products – An Introduction, Anticancer Natural Products, Antimicrobial Natural Products, Antimalarial and Antiparasitic Natural Products, Anti-inflammatory Natural Products, Neuroprotective Natural Products, Hepatoprotective Natural Products, Nephroprotective Natural Products, Cancer Chemopreventive Natural Products, Antipsoriatic Natural Products, Medicinal Natural Products in Osteoporosis, Antidiabetic Natural Products, Anti-obesity Natural Products, and much more. Presents a disease-focused perspective Includes the latest on the medicinal chemistry of natural products Covers natural products in drug delivery

Pharmacotherapeutic Botanicals for Cancer Chemoprevention

Pharmacotherapeutic Botanicals for Cancer Chemoprevention Book
Author : Manish Kumar,Ashita Sharma,Praveen Kumar
Publisher : Springer Nature
Release : 2020-07-20
ISBN : 9811559996
Language : En, Es, Fr & De

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Book Description :

The book presents a comprehensive and up-to-date overview of phytochemicals as efficient cancer therapeutics. Over the last few decades there has been a paradigm shift from conventional cancer therapeutic approaches to alternative and complementary medicinal approaches especially using phytoconstituents from natural products. As such, the book provides an in-depth understanding of phytochemicals targeting diverse signaling pathways involved in cancer along with the evaluation of the cancer modulatory effects of phytochemicals. It also highlights the potential modulatory effect of single nucleotide polymorphisms (SNPs) on the cancer-associated cellular pathways and their interactions with the phytochemicals. Further, it analyzes the drug delivery methods, bioavailability of active components of botanicals, and toxicity of phytochemicals. Lastly, the book elucidates the 3D cell culture and animal models systems to analyze the beneficial effects of phytochemicals in cancer.

Nutritional Antioxidant Therapies Treatments and Perspectives

Nutritional Antioxidant Therapies  Treatments and Perspectives Book
Author : Kaïs Hussain Al-Gubory,Ismail Laher
Publisher : Springer
Release : 2018-03-10
ISBN : 3319676253
Language : En, Es, Fr & De

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Book Description :

This book offers a collection of expert reviews on the use of plant-based antioxidant therapies in disease prevention and treatment. Topics discussed include the uses of plant and nutritional antioxidants in the contexts of reproductive health and prenatal development, healthcare and aging, noncommunicable chronic diseases, and environmental pollution. The text is complemented by a wealth of color figures and summary tables.

Curcumin in Health and Disease

Curcumin in Health and Disease Book
Author : Beatrice E. Bachmeier
Publisher : MDPI
Release : 2019-10-11
ISBN : 3039214497
Language : En, Es, Fr & De

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Book Description :

The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin’s antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs’ therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.

Dietary Polyphenols

Dietary Polyphenols Book
Author : Francisco A . Tomás-Barberán,Antonio González-Sarrías,Rocío García-Villalba
Publisher : John Wiley & Sons
Release : 2020-10-29
ISBN : 1119563747
Language : En, Es, Fr & De

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Book Description :

Presents recent research on metabolism and the health effects of polyphenols Consumer interest in the health benefits of many phenolic compounds found in plant foods and derivatives has grown considerably in recent years, giving rise to an increased demand for functional foods. Although preclinical and observational studies have promoted the protective properties of polyphenols for a range of chronic diseases, evidence has shown that most dietary polyphenols have little bioavailability. Once ingested, most of them are metabolized by either the intestinal enzymes or by the gut microbiota and then undergo extensive phase-II metabolism reaching significant concentrations of conjugated metabolites. They remain in the systemic circulation and target systemic tissues where trigger biological effects. The polyphenol-derived metabolites produced in humans are dependent upon the composition of the gut microbiota and the subject genetics. Thus all the metabolites do not show the same biological activity in different individuals. To fully understand the health effects of polyphenols, further clinical investigations are required. Dietary Polyphenols describes the latest findings on the polyphenol metabolism and reviews the current evidence on their health effects and that of their bioavailable metabolites. Emphasizing the importance of interindividual variability and the critical role of gut microbiota, this authoritative volume features contributions from recognized experts in the field, exploring specific families of extractable and non-extractable phenolic compounds that exhibit potential health effects. Topics include structural diversity of polyphenols and distribution in foods, bioavailability and bioaccessibility of phenolics, metabolism, and gastrointestinal absorption of various metabolites and their health effects. This comprehensive volume: Discusses the bioavailability, bioaccessibility, pharmacokinetics studies, and microbial metabolism of different groups of phenolic compounds Examines the interaction between polyphenols and gut microbiota Describes analytical methods for identifying and quantifying polyphenols in foods and biological samples Reviews recent epidemiological and clinical intervention studies showing protective effects of polyphenols Dietary Polyphenols: Metabolism and Health Effects is an important resource for scientists working in the area of dietary polyphenols and health effects, microbiota, and their interaction with other nutritional compounds, and for health professionals, nutritionists, dieticians, and clinical researchers with interest in the role of polyphenols in the prevention and treatment of chronic diseases

Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults

Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults Book
Author : Ronald Ross Watson
Publisher : Academic Press
Release : 2015-01-27
ISBN : 0124186866
Language : En, Es, Fr & De

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Book Description :

Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults focuses on the ways in which food and dietary supplements affect the major health problems of aging adults. Researchers in nutrition, diet, epidemiology, and aging studies, as well as healthcare providers who work with elderly patients will use this comprehensive resource as a tool in their long-term goal of preventing and treating chronic disease within the elderly. This book brings together a broad range of experts working on the different aspects of foods and dietary supplements (vitamins, herbs, plant extracts, etc.) in health promotion and disease prevention. They have contributed chapters which define a range of ways in which foods, nutriceuticals, and dietary supplements prevent disease and promote health in older adults. They begin by reviewing the medicinal role of foods, herbal, and dietary supplements in health promotion in older adults, as well as some of the most commonly used supplements in elder "self-medication." They review the most recent studies of how foods, herbal, and dietary supplements are effective in the prevention and treatment of cancer, cardiovascular disease, diabetes, and other obesity associated diseases in older adults. Then they consider alcohol, other drugs, and plant based drugs of abuse which can adversely affect the health of older adults. Lastly, they consider foods and dietary supplements in gene regulation in older adults. Investigates the important nutritional requirements of the aging population in health and in relation to various acute and chronic diseases Explores the nutritional effects of botanical extracts and components that can have important health promotion benefits, and risks, to ensure safe consumption Reviews studies of common diseases within the aging population including cancer, cardiovascular, metabolic, and infectious diseases that can alter the intake of foods, supplements, and/or requirements for various nutrients Investigates the mechanisms of action of components of foods and dietary supplements, in particular gene activation and epigenetics

Counteraction to Chemical and Biological Terrorism in East European Countries

Counteraction to Chemical and Biological Terrorism in East European Countries Book
Author : Christophor Dishovsky,Alexander Pivovarov
Publisher : Springer Science & Business Media
Release : 2009-05-05
ISBN : 9048123429
Language : En, Es, Fr & De

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Book Description :

The terrorist act with sarin gas in the Tokyo underground and the case with the spread of anthrax spores through the U.S. postal system stimulated the development of orga- zation of fight against terrorism on a national and global level. The goal of this wo- shop was assessment of scientific concepts and practical means for management of chemical and biological agents casualties in the area of terrorist attacks with emphasis on improving the problems and situation in Eastern European Countries. In this book are included the results of both theoretical and practical research of chemical and biological terrorism presented during the workshop. Different trends of research to fight against terrorism on both local and governmental level including some Eastern European countries are discussed. The scientific articles are grouped into those areas: – New approaches in counteraction to chemical and biological terrorism – Medical treatment and decontamination of casualties from chemical and biological agents – Diagnosis of exposure to chemical and biological agents – Development of protection against injuries from chemical and biological agents In these articles the following are emphasized: – Some aspects of national and global defense against chemical and biological terrorism – National action plans and global agreements on combating terrorism – The characteristics of the major specific injuries connected with chemical and biological terrorism – Threats of terroristic attacks – Epidemiological and clinical peculiarities, ways of diagnosing, medical tre- ment and preventive health care measures These problems are analyzed from an interdisciplinary perspective.

Natural Products and Cancer Signaling Isoprenoids Polyphenols and Flavonoids

Natural Products and Cancer Signaling  Isoprenoids  Polyphenols and Flavonoids Book
Author : Anonim
Publisher : Academic Press
Release : 2014-12-03
ISBN : 0128025271
Language : En, Es, Fr & De

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Book Description :

Natural compounds from a variety of natural resources including plants have emerged as important source of anticancer drug development. This special issue will highlight the significant advance in elucidating mechanisms of action of these natural compounds, focusing especially on isoprenoids and polyphenols/flavonoids. Informs and updates on all the latest developments in the field Contributions from leading authorities and industry experts

Nutrition Epigenetic Mechanisms and Human Disease

Nutrition  Epigenetic Mechanisms  and Human Disease Book
Author : Nilanjana Maulik,Gautam Maulik
Publisher : CRC Press
Release : 2010-12-03
ISBN : 1439804826
Language : En, Es, Fr & De

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Book Description :

As nutrition research is shifting its focus from epidemiology and physiology to effects of nutrients at the molecular level, a uniquely tailored diet that corresponds to the demands of our genetic signature is emerging as an indispensable need. Using high-throughput genomic tools, nutrigenomics unravels the influence of micro- and macronutrients as

Micronutrients and Health

Micronutrients and Health Book
Author : Kalanithi Nesaretnam,Lester Packer
Publisher : The American Oil Chemists Society
Release : 2001
ISBN : 9781893997196
Language : En, Es, Fr & De

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Book Description :

Download Micronutrients and Health book written by Kalanithi Nesaretnam,Lester Packer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Diet and Exercise in Cognitive Function and Neurological Diseases

Diet and Exercise in Cognitive Function and Neurological Diseases Book
Author : Akhlaq A. Farooqui,Tahira Farooqui
Publisher : John Wiley & Sons
Release : 2015-02-06
ISBN : 1118840569
Language : En, Es, Fr & De

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Book Description :

Diet and exercise have long been recognized as important components of a healthy lifestyle, as they have a great impact on improving cardiovascular and cerebrovascular functions, lowering the risk of metabolic disorders, and contributing to healthy aging. As a greater proportion of the world’s population is living longer, there has been increased interest in understanding the role of nutrition and exercise in long-term neurological health and cognitive function. Diet and Exercise in Cognitive Function and Neurological Diseases discusses the role and impact that nutrition and activity have on cognitive function and neurological health. The book is divided into two sections. The first section focuses on diet and its impact on neurobiological processes. Chapters focus on the impacts of specific diets, such as the Mediterranean, ketogenic and vegan diets, as well as the role of specific nutrients, fats, fatty acids, and calorie restriction on neurological health and cognitive function. The second section of the book focuses on exercise, and its role in maintaining cognitive function, reducing neuroinflammatory responses, regulating adult neurogenesis, and healthy brain aging. Other chapters look at the impact of exercise in the management of specific neurological disorders such Multiple Sclerosis and Parkinson’s Disease. Diet and Exercise in Cognitive Function and Neurological Diseases is a timely reference on the neurobiological interplay between diet and exercise on long-term brain health and cognitive function.

A Paradigm Shift to Prevent and Treat Alzheimer s Disease

A Paradigm Shift to Prevent and Treat Alzheimer s Disease Book
Author : Howard Friel,Sally A. Frautschy
Publisher : Academic Press
Release : 2017-07-18
ISBN : 012812279X
Language : En, Es, Fr & De

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Book Description :

A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gallate (EGCG) from green tea, and oleocanthal and oleuropein from olive oil, in addition to a special extract, EGb 761, from the leaves of Ginkgo biloba, the oldest living species of tree on earth. This book also presents a new analytical framework that convincingly favors a multi-targeting ("pleiotropic") approach to the prevention and treatment of complex chronic diseases, in contrast to the mono-targeting of the pharmaceutical model. A Paradigm Shift to Prevent and Treat Alzheimer’s Disease is a unique and exciting resource for pharmaceutical scientists, pharmacologists, neurologists, general practitioners, research scientists in various medical and life sciences, healthcare professionals in clinical and executive positions, conventional medical schools, schools of naturopathic medicine, healthcare and medical journalists, executives in both national public healthcare systems and private insurers, and informed general readers. Presents carefully compiled evidence supporting the need to shift from pharmaceutical-based mono-targeting to plant polyphenol-based pleiotropic targeting for the prevention and treatment of Alzheimer’s disease Includes valuable tables that aggregate pleiotropic pharmacological effects of the plant polyphenols on Alzheimer’s disease-related pathogenic hallmarks Highlights regulatory aspects and discusses the challenges and potential solutions with respect to bioavailability of certain plant polyphenols

Advances in Nutrition and Cancer

Advances in Nutrition and Cancer Book
Author : Vincenzo Zappia,Salvatore Panico,Gian Luigi Russo,Alfredo Budillon,Fulvio Della Ragione
Publisher : Springer Science & Business Media
Release : 2013-10-10
ISBN : 3642380077
Language : En, Es, Fr & De

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Book Description :

This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed “nutrition and cancer” from different perspectives and on the basis of distinct and up-to-date experimental approaches. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed. Issues of vital interest to the research community, such as epidemiological and experimental oncology (genetics, epigenetics, and the mechanisms of action of natural compounds in the diet), receive detailed consideration. A further key topic is the emerging molecular technologies (the “omics”) that can cast light on the interplay between nutrition and human malignancies. Chapters take the form of reviews that include sections presenting expert opinions.

Phytochemicals

Phytochemicals Book
Author : Toshiki Asao,Md Asaduzzaman
Publisher : BoD – Books on Demand
Release : 2018-11-07
ISBN : 1789843774
Language : En, Es, Fr & De

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Book Description :

Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.

Olives and Olive Oil in Health and Disease Prevention

Olives and Olive Oil in Health and Disease Prevention Book
Author : Victor R. Preedy,Ronald Ross Watson
Publisher : Academic Press
Release : 2010-03-23
ISBN : 9780080922201
Language : En, Es, Fr & De

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Book Description :

Long used in sacred ceremonies and associated with good health, the nutritional and health promoting benefits of olives and olive oils have been proven by an ever-increasing body of science. From cardiovascular benefits to anti-microbial, anti-cancer, antioxidant activity and effects on macrophages and aptoptosis to cellular and pathophysiollogical process, olives and olive oils are proving important in many healthful ways. For example, reactive components in olive oils or olive oil by-products have now been isolated and identified. These include tyrosol, hydroxytyrosol, 3,4-dihydroxyphenyl acetic acid elenolic acid and oleuropein. Oleic acid is the main monosaturated fatty acid of olive oil. These have putative protective effects and modulate the biochemistry of a variety of cell types including those of the vascular system. Some but not all components have been characterised by their putative pharmacological properties. It is possible that usage of these aforementioned products may have beneficial application in other disease. However, in order for this cross-fertilization to take place, a comprehensive understanding of olives and olive oils is required. Finding this knowledge in a single volume provides a key resource for scientists in a variety of food an nutritional roles. Key Features: * Explores olives and olive oil from their general aspects to the detailed level of important micro-and micronutrients * Includes coverage of various methodologies for analysis to help scientists and chemists determine the most appropriate option for their own studies, including those of olive-related compounds in other foods * Relates, in a single volume resource, information for food and nutritional chemists, pharmaceutical scientists, nutritionists and dieticians * Presents information in three key categories: General aspects of olives an olive oils; Nutritional, pharmacological and metabolic properties of olives and olive oil; Specific components of olive oil and their effects on tissue and body systems