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Polyphenols Mechanisms Of Action In Human Health And Disease

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Polyphenols in Human Health and Disease

Polyphenols in Human Health and Disease Book
Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Release : 2018-08-06
ISBN : 0128130075
Language : En, Es, Fr & De

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Book Description :

Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. Expands coverage on green tea, cocoa, wine, cumin and herbs Outlines their chemical properties, bioavailability and metabolomics Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols

Polyphenols Mechanisms of Action in Human Health and Disease

Polyphenols  Mechanisms of Action in Human Health and Disease Book
Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi, MD
Publisher : Academic Press
Release : 2018-08-22
ISBN : 9780128130063
Language : En, Es, Fr & De

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Book Description :

Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. Expands coverage on green tea, cocoa, wine, cumin and herbs Outlines their chemical properties, bioavailability and metabolomics Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols

Polyphenols in Human Health and Disease

Polyphenols in Human Health and Disease Book
Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Release : 2018-08-06
ISBN : 0128130091
Language : En, Es, Fr & De

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Book Description :

Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, obesity, diabetes and osteoporosis. This collection represents the contributions of an international group of experts in polyphenol research who share their expertise in endocrinology, public health, cardiology, pharmacology, agriculture and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted insights into the mechanisms of disease. This reference fills a void in research where nutritionists and alternative therapies may be applicable. Describes polyphenol modulation of blood flow and oxygenation as a potential mechanism of protection against vascular atherosclerosis Describes how polyphenols and antioxidants frequently change immune defenses and actions Focuses on the most important areas of research and provides insights into their relationships and translational opportunities

Polyphenols in Human Health and Disease

Polyphenols in Human Health and Disease Book
Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Release : 2013-10-26
ISBN : 012398467X
Language : En, Es, Fr & De

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Book Description :

Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. Explores neuronal protection by polyphenol metabolites and their application to medical care Defines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applications Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases

New Mechanisms of Action of Natural Antioxidants in Health and Disease

New Mechanisms of Action of Natural Antioxidants in Health and Disease Book
Author : Silvana Hrelia,Cristina Angeloni
Publisher : MDPI
Release : 2020-07-03
ISBN : 3039362682
Language : En, Es, Fr & De

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Book Description :

This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.

Dietary Polyphenols in Human Diseases

Dietary Polyphenols in Human Diseases Book
Author : Mithun Rudrapal
Publisher : CRC Press
Release : 2022-12-29
ISBN : 1000803236
Language : En, Es, Fr & De

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Book Description :

Diets rich in plant polyphenols or dietary polyphenols are the subject of increasing scientific interest because of their diverse range of health benefits and medicinal uses. This book, Dietary Polyphenols in Human Diseases: Advances and Challenges in Drug Discovery, fills the gap that exists in the current knowledge by presenting the latest information in the area of polyphenol-based drug discovery research. The book focuses on the current understanding of the beneficial effects on human health of diets rich in polyphenols and/or polyphenolic compounds derived from dietary sources (plant-based foods) and their possible preventive role in the management of chronic human diseases. In addition, biochemical mechanisms involved in the antioxidative effect of dietary polyphenols along with their bioavailability, pharmacokinetic, and toxicological considerations are also discussed herein. Key Features Presents health benefits and medicinal importance of dietary polyphenols having antioxidative effects and their possible preventive role against oxidative stress (OS)-induced chronic human diseases. Summarizes the latest understanding of the biochemical mechanism(s) involved in the antioxidative action of dietary polyphenols along with their bioavailability, pharmacokinetic, and toxicological considerations. Highlights novel approaches of drug discovery from dietary polyphenols through computational screening of bioactive phytochemical components. With contributions by a global team of experts (academics, scientists, and researchers), this book is intended to be a useful resource for a wider audience, particularly those working in the area of drug discovery and development research, such as discovery scientists, pharmaceutical scientists (R&D), formulation scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, clinicians, researchers, students, teachers, and many others.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Atta-ur Rahman
Publisher : Elsevier
Release : 2022-09-30
ISBN : 0323912524
Language : En, Es, Fr & De

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Book Description :

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

The Chemistry inside Spices Herbs Research and Development Volume 1

The Chemistry inside Spices   Herbs  Research and Development  Volume 1 Book
Author : Pankaj Kumar Chaurasia,Shashi Lata Bharati
Publisher : Bentham Science Publishers
Release : 2022-04-13
ISBN : 9815039571
Language : En, Es, Fr & De

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Book Description :

The Chemistry inside Spices & Herbs: Research and Development brings comprehensive information about the chemistry of spices and herbs with a focus on recent research in this field. The book is an extensive 2-part collection of 20 chapters contributed by experts in phytochemistry with the aim to give the reader deep knowledge about phytochemical constituents in herbal plants and their benefits. The contents include reviews on the biochemistry and biotechnology of spices and herbs, herbal medicines, biologically active compounds and their role in therapeutics among other topics. Chapters which highlight natural drugs and their role in different diseases and special plants of clinical significance are also included. Part I focuses on the general aspects of spice biotechnology, structure activity relationships and the natural products that can be used to treat different diseases - such as neurological diseases, inflammation, pain and infections. This part also covers information about phenolic compounds, flavonoids and turmeric supplements. This book is an ideal resource for scholars (in life sciences, phytomedicine and natural product chemistry) and general readers who want to understand the importance of herbs, spices and traditional medicine in pharmaceutical and clinical research.

Antioxidants in Health and Disease Volume 2

Antioxidants in Health and Disease Volume 2 Book
Author : Maurizio Battino,Francesca Giampieri
Publisher : MDPI
Release : 2018-05-18
ISBN : 3038429392
Language : En, Es, Fr & De

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Book Description :

This book is a printed edition of the Special Issue "Antioxidants in Health and Disease" that was published in Nutrients

The Renin Angiotensin System in Cardiovascular Disease

The Renin Angiotensin System in Cardiovascular Disease Book
Author : Naranjan S. Dhalla,Sukhwinder K. Bhullar,Anureet K. Shah
Publisher : Springer Nature
Release : 2023-02-02
ISBN : 3031149521
Language : En, Es, Fr & De

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Book Description :

This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in the development of different cardiovascular diseases due to the prolonged activation of RAS. Furthermore, biochemical mechanisms are outlined for the inhibition of this system by the blockade of angiotensin converting enzyme as well as angiotensin II type 1 receptors in patients suffering from cardiovascular abnormalities. Since cardiovascular disease is the number one cause of death worldwide, leading to approximately 17.9 million deaths each year, there is a keen interest in understanding the pathogenesis and improving its therapy. In this regard, we can attest that this book provides ample information about essential components of RAS and their role in the development of cardiovascular disease. From the selection of recognized global experts in their area of investigation, this book can be seen to cover diverse cardiovascular aspects and molecular and cellular mechanisms of angiotensin II action for the development of different cardiovascular abnormalities. It is our contention that this book will be most suitable for promoting knowledge in the field of RAS biology and will be of great interest to health professionals involved in both experimental and clinical cardiology as well as academic investigators and cardiovascular scientists, graduate students, and fellows worldwide.

Bioactive Compounds in Fermented Foods

Bioactive Compounds in Fermented Foods Book
Author : Amit Kumar Rai,Anu Appaiah K. A.
Publisher : CRC Press
Release : 2021-11-30
ISBN : 042964857X
Language : En, Es, Fr & De

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Book Description :

The volume reviews different types of bioactive components associated with food fermentation and their impact on human health. The diversity of microorganism responsible for the production of different types of fermented foods and beverages includes bacteria, yeasts, and fungi. Biotransformation of food constituent by microorganisms occurs during fermentation processes for the production of fermented food and in the gastrointestinal tract by gut microorganisms. This biotransformation results in production of specific bioactive compounds that are responsible for a wide range of health benefits. The bioactive compounds discussed in this book includes polyphenols, bioactive peptides, fibrinolytic enzymes, gama-amino butyric acids (GABA) exopolysaccharides, probiotic, prebiotic, symbiotic and antinutritional factors. These bioactive compounds are responsible for health benefits such as antioxidant, antihypertension, antimicrobial, cholesterol lowering, anticancer, obesity and antithrombotic properties. Advanced research in the field of food fermentation and their health benefits have resulted in commercialization of some of the fermented foods as functional foods. The traditional fermented foods consumed in different parts of the world and their health benefits are discussed in detail and the book concludes with recent advances in microbial transformation during gut fermentation and their impact on human health. There has been increasing interest among researchers on the proposed title in the last decade and the book brings updated information on research and advances in different types of health benefits exhibited by bioactive compounds in a wide range of fermented foods.

Frontiers in Clinical Drug Research Diabetes and Obesity Volume 6

Frontiers in Clinical Drug Research   Diabetes and Obesity  Volume 6 Book
Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
Release : 2021-11-05
ISBN : 9811479178
Language : En, Es, Fr & De

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Book Description :

Frontiers in Clinical Drug Research – Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. The sixth volume of this series features 6 reviews which are informative guides to therapy and drug administration in diabetes and metabolic syndrome, for both the medical specialist and the pharmacologist. - The failing heart in diabetes with special emphasis on prevention - Flavonoids as prominent anti-diabetic agents - Chemosensor in glucose monitoring, advances and challenges - Synergistic drugs and polyherbal formulations for obesity: current status and future prospectives - Urge for herbal anti-diabetic medicines towards clinical and therapeutic implications - Curcuma longa as dietary supplement and diabetes mellitus: evidence from experimental studies

Nutrition and Traumatic Brain Injury

Nutrition and Traumatic Brain Injury Book
Author : Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain
Publisher : National Academies Press
Release : 2011-07-01
ISBN : 0309210089
Language : En, Es, Fr & De

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Book Description :

Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.

Plant Metabolites Methods Applications and Prospects

Plant Metabolites  Methods  Applications and Prospects Book
Author : Swapna Thacheril Sukumaran,Shiburaj Sugathan,Sabu Abdulhameed
Publisher : Springer Nature
Release : 2020-11-28
ISBN : 9811551367
Language : En, Es, Fr & De

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Book Description :

Food security and the medicinal needs of billions of people around the world are pressing global issues, and the biodiversity and sustainable utilization of plants is of great significance in this context. Further, ethnobotanical studies are vital in the discovery of new drugs from indigenous medicinal plants, and plants with industrially important metabolites need to be cultivated to meet the growing market demand. In addition, the production of plant metabolites under in vitro conditions also has tremendous possibilities. The totipotency of plant cells plays a valuable role in the sustainable utilization of plant resources through cell, tissue and organ culture. At the same time, production can be enhanced using productive cell lines, treatment with elicitors, changing nutritional parameters and metabolic engineering. This book provides state-of-the-art information on biodiversity, conservation, ethnobotany, various aspects of In vitro secondary metabolite production, bioprospecting from various plant groups and drug discovery. It also discusses methods of extracting and characterizing drug leads from plant sources.​

Fermented Food Products

Fermented Food Products Book
Author : A. Sankaranarayanan,N. Amaresan,D. Dhanasekaran
Publisher : CRC Press
Release : 2019-12-06
ISBN : 1000761096
Language : En, Es, Fr & De

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Book Description :

Fermented food play an important proactive role in the human diet. In many developing and under developed countries, fermented food is a cheap source of nutrition. Currently, more than 3500 different fermented foods are consumed by humans throughout the world; many are indigenous and produced in small quantities, however, the consumption of many fermented foods has gradually increased. Fermented Food Products presents in-depth insights into various microbes involved in the production of fermented foods throughout the world. It also focuses on recent developments in the fermented food microbiology field along with biochemical changes that are happening during the fermentation process. • Describes various fermented food products, especially indigenous products • Presents health benefits of fermented food products • Explains mechans involved in the production of fermented foods • Discusses molecular tools and its applications and therapeutic uses of fermented foods The book provides a comprehensive account about diversified ethnic fermented food products. Readers will get updated information regarding various types of fermented food products and will learn the effect these fermented food products have on human health.

Functional Foods and their Implications for Health Promotion

Functional Foods and their Implications for Health Promotion Book
Author : Ioannis Zabetakis,Ronan Lordan,Alexandros Tsoupras,Dipak Ramji
Publisher : Academic Press
Release : 2022-12-03
ISBN : 0128238127
Language : En, Es, Fr & De

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Book Description :

Functional Foods and Their Implications for Health Promotion presents functional foods, from raw ingredients to the final product, providing a detailed explanation on how these foods work and an overview of their impact on health. The book presents the functions of food against disease and discusses how healthier foods can be produced. Broken into four parts, the book presents a deep dive into plant-derived functional foods, dairy foods, marine food and beverages. The book includes case studies, applications, literature reviews and coverage of recent developments. Intended for nutritionists, dieticians, food technologists, as well as students and researchers working in nutrition, dietetics, and food science, this book is sure to be a welcomed resource. Uses flow diagrams to highlight the effects of processing on produced functional foods Combines information on the production/formulation of the food with data on bioactivities and bioavailability Presents whole foods and not food components while also focusing on functionality and availability

Evidence Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease

Evidence Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease Book
Author : Asim K. Duttaroy
Publisher : Academic Press
Release : 2021-07-08
ISBN : 0128221941
Language : En, Es, Fr & De

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Book Description :

Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease explores a wide range of studies from clinical investigations to mechanistic research, covering the actions of bioactives on specific tissues and cells in intestinal, neurological, immunological and cardiovascular health and disease, including cancers. The book also focuses on metabolism, mechanisms of actions, tissue-specific effects, and the structure–function relationships between clinical trial, ex vivo and in vitro data. Written for nutrition researchers, clinical researchers, dieticians, and others working in and studying health-related fields, this book highlights the concepts surrounding the preventive and therapeutic impacts of bioactive foods. Presents information on the prevention of disease using bioactive compounds Consolidates the research outcome from a variety of sources on specific bioactive foods Contains coverage of bioactive lipids and lipid mediators, bioactive phytochemicals, probiotics, bioactive proteins, peptides, polysaccharides, fibers and sphingolipids

Functional Foods and Nutraceuticals

Functional Foods and Nutraceuticals Book
Author : Chukwuebuka Egbuna,Genevieve Dable Tupas
Publisher : Springer Nature
Release : 2020-08-24
ISBN : 3030423190
Language : En, Es, Fr & De

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Book Description :

Functional foods and nutraceuticals are food products that naturally offer or have been modified to offer additional health benefits beyond basic nutrition. As such products have surged in popularity in recent years, it is crucial that researchers and manufacturers understand the concepts underpinning functional foods and the opportunity they represent to improve human health, reduce healthcare costs, and support economic development worldwide. Functional Foods and Nutraceuticals: Bioactive Components, Formulations and Innovations presents a guide to functional foods from experienced professionals in key institutions around the world. The text provides background information on the health benefits, bioavailability, and safety measurements of functional foods and nutraceuticals. Subsequent chapters detail the bioactive components in functional foods responsible for these health benefits, as well as the different formulations of these products and recent innovations spurred by consumer demands. Authors emphasize product development for increased marketability, taking into account safety issues associated with functional food adulteration and solutions to be found in GMP adherence. Various food preservation methods aimed at enhancing the quality and shelf life of functional food are also highlighted. Functional Foods and Nutraceuticals: Bioactive Components, Formulations and Innovations is the first of its kind, designed to be useful to students, teachers, nutritionists, food scientists, food technologists and public health regulators alike.

Beat Arthritis Naturally

Beat Arthritis Naturally Book
Author : Emily Johnson
Publisher : Yellow Kite
Release : 2021-05-13
ISBN : 152934770X
Language : En, Es, Fr & De

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Book Description :

Are you looking for natural remedies to help manage your arthritis symptoms? Emily Johnson, the founder of Arthritis Foodie, has written the ultimate guide to living well with arthritis. After a five year battle with the condition, Emily embarked on a journey of healing - with food, exercise and healthy living - and now with her debut book she puts us on the path to taking back control of our own bodies. Beat Arthritis Naturally shares Emily's top tips and tricks for managing symptoms, along with quick exercise sequences and delicious recipes made with unprocessed whole foods, such as Cajun Salmon Burgers, Warming Parsnip Soup and Bright Blueberry Muffins. Emily delves into a variety of topics to help you naturally feel better, including: - Healthy delicious recipes - Key anti-inflammatory foods and potential inflammatory foods - Pain management - The importance of sleep - Mindset and how to think more positively Combining Emily's own challenges with seronegative arthritis and backed-up expert advice from leading therapists and rheumatologists, Beat Arthritis Naturally will give you the confidence you need to live a healthier and happier life. 'Emily has compiled a fantastic book full of useful and scientifically robust information about how lifestyle and food can help with this debilitating group of conditions. Most people resort to medications alone, when actually we know just how impactful lifestyle can be. Emily is banging the drum for arthritis patients everywhere and this is a must read for anyone suffering alone and looking to improve their wellbeing holistically.' - Dr Rupy Aujla, MBBS, BSc, MRCGP, Founder Doctor's Kitchen

Plant Extracts Applications in the Food Industry

Plant Extracts  Applications in the Food Industry Book
Author : Shabir Ahmad Mir,Annamalai Manickavasagan,Manzoor Ahmad Shah
Publisher : Academic Press
Release : 2021-12-04
ISBN : 0128224932
Language : En, Es, Fr & De

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Book Description :

Plant Extracts in Food Applications is the first book of its kind focusing on the application of plant extracts in the food industry. Topics cover sources, extraction and encapsulation techniques, the chemistry and stability of plant extracts, antimicrobials, preservatives, nutrient enhancers, enzymes, flavoring and coloring agents, packaging aid, health benefits, opportunities and the challenges surrounding the use of plant extracts in food applications. Written by several experts in the field, this book is a valuable resource for students, scientists, and professionals in food science, food chemistry and nutrition. Concerns and potential risks regarding the use of synthetic chemicals have renewed the interests of consumers using natural and safe alternatives. Plant extracts represent an interesting ingredient, mainly due to their natural origin and phytochemical properties, allowing for obtaining active materials to extend shelf-life and add value to the product. Presents chapters that deal with different sources of plant extracts and their applications in the food industry Covers the various extraction procedures which are used for plant extracts Includes the health benefits and stability of plant extracts Provides the role of plant extracts for shelf life enhancement, packaging aid, and as flavoring and coloring agents