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Physiology And Pathology Of Chloride Transporters And Channels In The Nervous System

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Physiology and Pathology of Chloride Transporters and Channels in the Nervous System

Physiology and Pathology of Chloride Transporters and Channels in the Nervous System Book
Author : F. Javier Alvarez-Leefmans,Eric Delpire
Publisher : Academic Press
Release : 2009-08-22
ISBN : 9780080922034
Language : En, Es, Fr & De

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Book Description :

The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change in this simplistic view. We now know that most animal cells, neurons included, exhibit a non-equilibrium distribution of Cl- across their plasma membranes. Over the last 10 to 15 years, with the growth of molecular biology and the advent of new optical methods, an enormous amount of exciting new information has become available on the molecular structure and function of Cl- channels and carriers. In nerve cells, Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control. Disruption of Cl- homeostasis in neurons underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation. This book is about how chloride ions are regulated and how they cross the plasma membrane of neurons. It spans from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases. The first comprehensive book on the structure, molecular biology, cell physiology, and role in diseases of chloride transporters / channels in the nervous system in almost 20 years Chloride is the most abundant free anion in animal cells. THis book summarizes and integrates for the first time the important research of the past two decades that has shown that Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control The first book that systematically discusses the result of disruption of Cl- homeostasis in neurons which underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation Spanning topics from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases Involves all of the leading researchers in the field Includes an extensive introductory section that covers basic thermodynamic and kinetics aspects of Cl- transport, as well as current methods for studying Cl- regulation, spanning from fluorescent dyes in single cells to knock-out models to make the book available for a growing population of graduate students and postdocs entering the field

Research Awards Index

Research Awards Index Book
Author : Anonim
Publisher : Unknown
Release : 1984
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Research Awards Index book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Handbook of Physiology The gastrointestinal system v 1 pt 1 2 Motility and circulation

Handbook of Physiology  The gastrointestinal system  v  1  pt  1 2  Motility and circulation Book
Author : American Physiological Society (1887- )
Publisher : Unknown
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Handbook of Physiology The gastrointestinal system v 1 pt 1 2 Motility and circulation book written by American Physiological Society (1887- ), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Handbook of Physiology

Handbook of Physiology Book
Author : Michael Field
Publisher : Unknown
Release : 1991
ISBN : 9780195208177
Language : En, Es, Fr & De

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Book Description :

(1E 1968) Comprehensive reference to structure/function intestinal transport of inorganic ions & organic compounds.

Cambridge Scientific Biochemistry Abstracts

Cambridge Scientific Biochemistry Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cambridge Scientific Biochemistry Abstracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Physiology and Pathophysiology of the Cerebrospinal Fluid

Physiology and Pathophysiology of the Cerebrospinal Fluid Book
Author : Hugh Davson,Keasley Welch,Malcolm Beverley Segal
Publisher : Unknown
Release : 1987
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Physiology and Pathophysiology of the Cerebrospinal Fluid book written by Hugh Davson,Keasley Welch,Malcolm Beverley Segal, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

CSA Neurosciences Abstracts

CSA Neurosciences Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download CSA Neurosciences Abstracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Physiology

Physiology Book
Author : Matthew N. Levy
Publisher : Mosby Incorporated
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Seeking to emphasize broad concepts and principles, this textbook explains physiology with the understanding that one of the central goals of physiology is the elucidation of organisms' ability to maintain homeostasis. Berne (emeritus, molecular physiology and biological physics, U. of Virginia Health Sciences Center), Levy (emeritus physiology and biomedical engineering, Case Western Reserve U.), Koeppen (medicine and physiology, U. of Connecticut Health Center), and Stanton (physiology, Dartmouth Medical School), present eight sections covering cellular physiology and the nervous, muscle, cardiovascular, respiratory, gastrointestinal, renal, and endocrine systems. The text is heavily illustrated with line drawings. Cited in Brandon-Hill. Annotation (c)2003 Book News, Inc., Portland, OR (booknews.com).

The Kidney

The Kidney Book
Author : Donald W. Seldin,Gerhard H. Giebisch
Publisher : Unknown
Release : 1985
ISBN : 9780890049280
Language : En, Es, Fr & De

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Book Description :

Download The Kidney book written by Donald W. Seldin,Gerhard H. Giebisch, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Fluid Electrolytes

Fluid   Electrolytes Book
Author : Martin G. Cogan
Publisher : McGraw-Hill/Appleton & Lange
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Fluid Electrolytes book written by Martin G. Cogan, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Aquatic Sciences and Fisheries Abstracts

Aquatic Sciences and Fisheries Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Acid base and Electrolyte Disorders

Acid base and Electrolyte Disorders Book
Author : Thomas D. DuBose,L. Lee Hamm
Publisher : W B Saunders Company
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This companion to Brenner and Rector's The Kidney offers a concise, practical approach to acid-base and electrolyte disorders, emphasizing pathophysiology and its link to a logical diagnostic approach in treating these disorders. Unlike other traditional textbooks on the subject, ACID BASE AND ELECTROLYTE DISORDERS, focuses less on physiological and pathophysiological concepts and more on providing specific recommendations for therapy and patient care - resulting in an excellent clinical resource that is also an ideal core curriculum or exam review. Many of the topics in this book are not covered in any other resource, including acid-base and electrolyte disorders in the critical care setting. In addition, recent advances in fast-developing areas such as genetic and molecular biology are discussed in detail. Emphasizes acid-base and electrolyte abnormalities in the critical care setting - a topic not fully covered in any other resource. Includes the most up-to-date information on hot topics such as molecular biology and genetics of tubular transport abnormalities, hypertension, and calcium, sodium, and potassium homeostasis. Authors and contributors are experts in their field, providing the most authoritative information available. Figures and tables throughout the book help clarify important concepts. A detailed reference list for each chapter directs the reader to sources for further information, and readers are referred back to Brenner and Rector's The Kidney for complete discussions the complex physiology of certain disorders.

Gastroenterology

Gastroenterology Book
Author : Anonim
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Monthly. Abstracts from world literature about all aspects of gastrointestinal diseases and infections. Classified arrangement of entries. Subject, author indexes. About 2400 abstracts, 1971.

Handbook of Physiology The gastrointestinal system

Handbook of Physiology  The gastrointestinal system Book
Author : John R. Pappenheimer,American Physiological Society (1887- )
Publisher : Unknown
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Handbook of Physiology The gastrointestinal system book written by John R. Pappenheimer,American Physiological Society (1887- ), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Handbook of Physiology

Handbook of Physiology Book
Author : Anonim
Publisher : Unknown
Release : 1977
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Handbook of Physiology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Benzodiazepine GABA Receptors and Chloride Channels

Benzodiazepine GABA Receptors and Chloride Channels Book
Author : Richard W. Olsen,J. Craig Venter
Publisher : Unknown
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The fifth volume in the series is the first to deal exclusively with a single type of receptor. Contributions represent the most up-to-date research in the benzodiazepine/GABA receptor-chloride channel complex, an extremely interesting protein of great neurobiological significance. Major workers in the field describe the history of GABA receptors and the benzodiazepine connection''. Lays out background material in a particularly clear fashion to allow readers from outside the field to quickly grasp the main points. Presents in detail the allosteric interactions between the various components of the benzodiazepine/GABA receptor complex from the points of view of several authors, so that readers can choose their level of involvement with these details. Includes the most recent advances on the biochemical purification, characterization, and development of monoclonal antibodies for the benzodiazepine/GABA receptor protein.

Medical Research Centres

Medical Research Centres Book
Author : Informa Healthcare
Publisher : Unknown
Release : 1995
ISBN : 9781860670176
Language : En, Es, Fr & De

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Book Description :

Focuses on research and development centers in the areas of medical and biomedical sciences including those in anatomy, biochemistry, clinical medicine, dentistry, drugs, genetics, immunology, neoplasms, pharmaceutical technology, and surgery.

Dissertation Abstracts International

Dissertation Abstracts International Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Dissertation Abstracts International book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Excerpta Medica

Excerpta Medica Book
Author : Anonim
Publisher : Unknown
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Monthly. References and abstracts to international journal literature in the field of physiology. Classified arrangement of entries. Subject, author index.

Brenner Rector s the Kidney

Brenner   Rector s the Kidney Book
Author : Barry M. Brenner,Samuel A. Levine,Floyd C. Rector
Publisher : W B Saunders Company
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This essential text has expanded the scope of topics covered, in particular by adding 10 new chapter headings in addition to the many already added to previous editions.