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Physicochemical Modification Of Curcumin And The Impact On Biological Activities

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Curcumin in Health and Disease

Curcumin in Health and Disease Book
Author : Beatrice E. Bachmeier
Publisher : MDPI
Release : 2019-10-11
ISBN : 3039214497
Language : En, Es, Fr & De

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Book Description :

The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin’s antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs’ therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.

Micronutrients and Health

Micronutrients and Health Book
Author : Kalanithi Nesaretnam,Lester Packer
Publisher : The American Oil Chemists Society
Release : 2001
ISBN : 9781893997196
Language : En, Es, Fr & De

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Book Description :

Download Micronutrients and Health book written by Kalanithi Nesaretnam,Lester Packer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Environmental Contaminants and Medicinal Plants Action on Female Reproduction

Environmental Contaminants and Medicinal Plants Action on Female Reproduction Book
Author : Alexander V. Sirotkin,Adriana Kolesarova
Publisher : Academic Press
Release : 2022-02-08
ISBN : 0323860125
Language : En, Es, Fr & De

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Book Description :

Environmental Contaminants and Medicinal Plants Action on Female Reproduction discusses the problem of environmental pollution, medicinal and food plants, and their impact on reproduction. The book describes the mechanisms of environmental contaminants' action, outlines the key causes of their harmful impact on reproduction, and explores what regulatory substances and processes should be targeted due to the negative effect of pollutants on reproduction. Furthermore, it describes the provenance, properties, physiological and therapeutic effects, and possible areas of application of the known medicinal and functional food plants and their constituents with a focus on female reproductive processes. This book will be a useful resource for reproductive biologists, specialists in assisted reproduction, animal production and phytotherapy, toxicologists, pharmacologists, pharmaceutical scientists, endocrinologists, medicinal and natural product chemists, nutritionists and others engaged in the study of environmental contaminants and medicinal and functional food plants. Discusses common environmental contaminants that affect female reproductive processes and the mechanisms of their effects Covers plants and their active substances as potential protectives to environmental contaminants Examines how medicinal plants affect female reproductive processes, the mechanisms of their effects, and what plant molecules are responsible for the positive effects

Intelligent Biotechnologies of Natural and Synthetic Biologically Active Substances

Intelligent Biotechnologies of Natural and Synthetic Biologically Active Substances Book
Author : Vladimir Kurchenko
Publisher : Springer Nature
Release : 2022-10-01
ISBN : 3030966410
Language : En, Es, Fr & De

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Book Description :

Download Intelligent Biotechnologies of Natural and Synthetic Biologically Active Substances book written by Vladimir Kurchenko, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nanoengineering of Biomaterials

Nanoengineering of Biomaterials Book
Author : Sougata Jana,Subrata Jana
Publisher : John Wiley & Sons
Release : 2021-12-28
ISBN : 3527349049
Language : En, Es, Fr & De

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Book Description :

A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.

Modified Atmosphere and Active Packaging Technologies

Modified Atmosphere and Active Packaging Technologies Book
Author : Ioannis Arvanitoyannis
Publisher : CRC Press
Release : 2012-06-12
ISBN : 1439800456
Language : En, Es, Fr & De

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Book Description :

Many factors are relevant in making the proper choice of food packaging material, including those related to shelf life and biodegradability. To meet these demands, new processing and preservation techniques have arisen, most notably modified atmosphere packaging (MAP) and active packaging (AP). Modified Atmosphere and Active Packaging Technologies

Nutraceuticals and Health Care

Nutraceuticals and Health Care Book
Author : Jasmeet Kour,Gulzar Ahmad Nayik
Publisher : Academic Press
Release : 2021-11-26
ISBN : 0323886175
Language : En, Es, Fr & De

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Book Description :

Nutraceuticals and Health Care explores the role of plant-based nutraceuticals as food ingredients and as therapeutic agents for preventing various diseases. The book assesses the role of nutraceuticals in addressing cardiovascular disease, cancer, diabetes, and obesity by highlighting the derivatives, extraction, chemistry, mechanism of action, pharmacology, bioavailability, and safety of specific nutraceuticals. It analyzes twenty one nutraceuticals in a systematic way, providing a welcomed reference for nutrition researchers, nutritionists and dieticians, as well as other scientists studying related areas in food science, technology or agriculture. Students studying related topics will also benefit from this material. Serves as a foundation for analyzing the efficiency and validity of various plant-derived nutraceuticals Explores the use of nutraceuticals as a therapeutic tool in the prevention of chronic and degenerative diseases Highlights the derivatives, extraction, chemistry, mechanism of action, pharmacology, bioavailability, and safety of specific nutraceuticals

Turmeric

Turmeric Book
Author : P. N. Ravindran,K. Nirmal Babu,Kandaswamy Sivaraman
Publisher : CRC Press
Release : 2007-03-01
ISBN : 9781420006322
Language : En, Es, Fr & De

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Book Description :

For the last 6000 years turmeric has been used in Ayurvedic medicine to alleviate pain, balance digestion, purify body and mind, clear skin diseases, expel phlegm, and invigorate the blood. Nowadays, this plant has acquired great importance with its anti-aging, anti-cancer, anti-Altzheimer, antioxidant, and a variety of other medicinal properties. The need of the hour is to verify and validate the traditional uses by subjecting them to proper experimental studies. To do this effectively there needs to be a single comprehensive source of the knowledge to date. Turmeric: the genus Curcuma is the first comprehensive monographic treatment on turmeric. It covers all aspects of turmeric including botany, genetic resources, crop improvement, processing, biotechnology, pharmacology, medicinal and traditional uses, and its use as a spice and flavoring. Bringing together the premier experts in the field from India, Japan, UK, and USA, this book offers the most thorough examination of the cultivation, market trends, processing, and products as well as pharmacokinetic and medicinal properties of this highly regarded spice. While Ayurveda has known for millennia that turmeric cleanses the body, modern science has now discovered that it produces glutathione-s-transferase that detoxifies the body and therefore strengthens the liver, heart, and immune system. By comparing traditional uses with modern scientific discoveries, the text provides a complete view of the medicinal value and health benefits of turmeric. Heavily referenced with an exhaustive bibliography at the end of each chapter, the book collects and collates the currently available data on turmeric. Covering everything from cultivation to medicine, Turmeric: the Genus Curcuma serves as an invaluable reference for those involved with agriculture, marketing, processing or product development, and may function as a catalyst for future research into the health benefits and applications of turmeric.

Whey Protein Production Chemistry Functionality and Applications

Whey Protein Production  Chemistry  Functionality  and Applications Book
Author : Mingruo Guo
Publisher : Wiley
Release : 2019-04-08
ISBN : 111925602X
Language : En, Es, Fr & De

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Book Description :

An up-to-date overview of the dynamic field of whey protein utilization Whey Protein Production, Chemistry, Functionality and Applications explores the science and technology behind the rapidly increasing popularity of this most versatile of dairy by-products. With its richly nutritious qualities, whey protein has been widely used in the food industry for many years. The last decade has, however, seen manufacturers develop many innovative and exciting new applications for it, both in food and other areas. Taking account of these advances, this insightful work offers a full explanation of the technological and chemical breakthroughs that have made whey protein more in-demand than ever before. Topics covered include manufacturing technologies, thermal and chemical modifications, non-food uses, denaturation and interactions, and more. In its broad scope, the book encompasses: An up-to-date overview of recent developments and new applications Breakdowns of the chemical, nutritional, and functional properties of whey protein Commentary on the current and future outlooks of the whey protein market Examinations of the methods and manufacturing technologies that enable whey protein recovery A full guide to the numerous applications of whey protein in food production and other industries Whey Protein Production, Chemistry, Functionality and Applications is an unparalleled source of information on this highly adaptable and much sought-after commodity, and is essential reading for food and dairy scientists, researchers and graduate students, and professionals working in the food formulation and dairy processing industries.

Encyclopedia of Polymer Applications 3 Volume Set

Encyclopedia of Polymer Applications  3 Volume Set Book
Author : Munmaya Mishra
Publisher : CRC Press
Release : 2018-12-17
ISBN : 1351019406
Language : En, Es, Fr & De

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Book Description :

Undoubtedly the applications of polymers are rapidly evolving. Technology is continually changing and quickly advancing as polymers are needed to solve a variety of day-to-day challenges leading to improvements in quality of life. The Encyclopedia of Polymer Applications presents state-of-the-art research and development on the applications of polymers. This groundbreaking work provides important overviews to help stimulate further advancements in all areas of polymers. This comprehensive multi-volume reference includes articles contributed from a diverse and global team of renowned researchers. It offers a broad-based perspective on a multitude of topics in a variety of applications, as well as detailed research information, figures, tables, illustrations, and references. The encyclopedia provides introductions, classifications, properties, selection, types, technologies, shelf-life, recycling, testing and applications for each of the entries where applicable. It features critical content for both novices and experts including, engineers, scientists (polymer scientists, materials scientists, biomedical engineers, macromolecular chemists), researchers, and students, as well as interested readers in academia, industry, and research institutions.

Herbs and Spices

Herbs and Spices Book
Author : Rabia Shabir Ahmad
Publisher : BoD – Books on Demand
Release : 2021-12-01
ISBN : 1839696087
Language : En, Es, Fr & De

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Book Description :

Herbs and Spices - New Processing Technologies is a collection of research and review chapters offering a comprehensive overview of recent developments in the field of herbs and spices, with a focus on plants containing bioactive components and the utilization of novel processing technologies in the development of functional products. The book consists of four sections containing fourteen chapters written by various researchers and edited by an expert active in the research of plants and bioactive compounds.

Advances in Spectroscopy Molecules to Materials

Advances in Spectroscopy  Molecules to Materials Book
Author : Dheeraj Kumar Singh,Sourav Das,Arnulf Materny
Publisher : Springer Nature
Release : 2019-10-24
ISBN : 9811502021
Language : En, Es, Fr & De

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Book Description :

This book presents and discusses recent developments in the broad field of spectroscopy, providing the reader with an updated overview. The main objective is to introduce them to recent innovations and current trends in spectroscopy applied to molecules and materials. The book also brings together experimentalists and theoreticians to highlight the multidimensional aspects of spectroscopy and discuss the latest issues. Accordingly, it provides insights not only into the general goals of spectroscopy, but also into how the various spectroscopic techniques represent a toolbox that can be used to gain a more detailed understanding of molecular systems and complex chemical problems. Besides technical aspects, basic theoretical interpretations of spectroscopic results are also presented. The spectroscopy techniques discussed include UV-visible absorption spectroscopy, Raman spectroscopy, IR absorption spectroscopy, fluorescence spectroscopy, and time-resolved spectroscopy. In turn, basic tools like lasers and theoretical modeling approaches are also presented. Lastly, applications for the characterization of fundamental properties of molecules (environmental aspects, biomolecules, pharmaceutical drugs, hazardous molecules, etc.) and materials (nanomaterials, nuclear chemistry materials, biomaterials, etc.) are discussed. Given its scope, the book offers a valuable resource for researchers from various branches of science, and presents new techniques that can be applied to their specific problems.

Curcumin for Neurological and Psychiatric Disorders

Curcumin for Neurological and Psychiatric Disorders Book
Author : Tahira Farooqui,Akhlaq A. Farooqui
Publisher : Academic Press
Release : 2019-03-16
ISBN : 0128154624
Language : En, Es, Fr & De

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Book Description :

Curcumin for Neurological and Psychiatric Disorders: Neurochemical and Pharmacological Properties focuses on the different molecular mechanisms underlying curcumin-mediated beneficial effects in neurological diseases. The book's editors discuss the neurochemical and pharmacological properties of curcumin, followed by the effect of curcumin in neurotraumatic diseases, neurodegenerative diseases, and neuropsychiatric diseases. The book also offers a perspective on future studies on the treatment of neurological disorders. The beneficial effects of curcumin have been observed both in cultured cells and in animal models, thus paving the way for ongoing present and future human clinical trials. Curcumin produces antioxidant and anti-inflammatory effects not only by blocking oxidative stress and neuroinflammation in neurotraumatic and neurodegenerative diseases, but also by restoring cellular homeostasis and rebalancing redox equilibrium. Identifies molecular mechanisms of curcumin effects in neurological diseases Includes effects on neurotraumatic, neurodegenerative and psychiatric diseases Covers the antioxidant, anti-inflammatory and immunomodulatory effects of curcumin Examines curcumin’s potential in developing new therapeutic drugs

Polymers for Food Applications

Polymers for Food Applications Book
Author : Tomy J. Gutiérrez
Publisher : Springer
Release : 2018-08-09
ISBN : 3319946250
Language : En, Es, Fr & De

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Book Description :

This book presents an exhaustive review on the use of polymers for food applications. Polymer-based systems for food applications such as: films, foams, nano- and micro-encapsulated, emulsions, hydrogels, prebiotics, 3D food printing, edible polymers for the development of foods for people with special feeding regimes, sensors, among others, have been analyzed in this work.

Nano and Microscale Drug Delivery Systems

Nano  and Microscale Drug Delivery Systems Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2017-03-27
ISBN : 0323527280
Language : En, Es, Fr & De

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Book Description :

Nano- and Microscale Drug Delivery Systems: Design and Fabrication presents the developments that have taken place in recent years in the field of micro- and nanoscale drug delivery systems. Particular attention is assigned to the fabrication and design of drug delivery systems in order to i) reduce the side effects of therapeutic agents, ii) increase their pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. This book is designed to offer a cogent, concise overview of current scholarship in this important area of research through its focus on the characterization and fabrication of a variety of nanomaterials for drug delivery applications. It is an invaluable reference source for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems. Shows how micro- and nanomaterials can be engineered to create more effective drug delivery systems Summarizes current nanotechnology research in the field of drug delivery systems Explores the pros and cons of using particular nanomaterials as therapeutic agents Serves as a valuable reference for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems

Veterinary Herbal Medicine

Veterinary Herbal Medicine Book
Author : Susan G. Wynn,Barbara Fougère
Publisher : Elsevier Health Sciences
Release : 2007
ISBN : 0323029981
Language : En, Es, Fr & De

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Book Description :

This full-color text and practical clinical reference provides comprehensive information on herbal remedies for both large and small animal species. Key coverage includes clinical uses of medicinal plants, specific information on how to formulate herbal remedies, a systems-based review of plant-based medicine, and in-depth information on the different animal species--dog, cat, avian and exotic, equine, food animal, and poultry.

Handbook of Polyester Drug Delivery Systems

Handbook of Polyester Drug Delivery Systems Book
Author : M. N. V. Ravi Kumar
Publisher : CRC Press
Release : 2017-03-27
ISBN : 1315341166
Language : En, Es, Fr & De

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Book Description :

In the quest for innovative drug delivery systems attempting to meet the unmet needs in pharmaceutical space, research has taken a much more complicated path that poses a significant challenge for translation. Despite the progress made with novel materials, polyesters still remain at the helm of drug delivery technologies. This book provides a single source of reference of polyester drug delivery systems that covers a broad spectrum of materials design, manufacturing techniques, and applications.

Legumes

Legumes Book
Author : Maria Ángeles Martín-Cabrejas
Publisher : Royal Society of Chemistry
Release : 2019-01-02
ISBN : 1788016750
Language : En, Es, Fr & De

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Book Description :

Legumes have high potential for improving the nutritional quality of foods, but limited data on their bioactive compounds exists. Results of clinical and epidemiological studies suggest that natural antioxidants can protect us against oxidative stress that is closely associated with cancer and cardiovascular disease. Legumes are a valuable source of bioactive compounds such as phenolic compounds, peptides and non-nutritional factors. They are rich in several important micronutrients, including potassium, magnesium, folate, iron, and zinc, and are an important source of protein in vegetarian diets. They are among the only plant foods that provide significant amounts of the amino acid, lysine. Commonly consumed legumes are also rich in total and soluble fibre as well as in resistant starch. This book provides a comprehensive overview of the antioxidant activity and health aspects of legumes. The international spread of contributors will describe the key factors that influence consumer acceptance of legumes in the diet, as well as the known functional properties of legumes and legume based food products. It will serve as an excellent and up-to-date reference for food scientists, food chemists, researchers in human nutrition, dietetics and the chemistry of natural compounds.

The Discovery and Utility of Chemical Probes in Target Discovery

The Discovery and Utility of Chemical Probes in Target Discovery Book
Author : Paul Brennan,Saleta Vazquez-Rodriguez
Publisher : Royal Society of Chemistry
Release : 2020-11-25
ISBN : 1788015894
Language : En, Es, Fr & De

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Book Description :

Numerous genetic methods can be utilised to link a phenotype to a single molecular target but annotated small molecule chemical probes and even entire chemogenomic libraries are increasingly being used as a complementary approach. This book will comprehensively cover the state of the art in chemical probes and best practice for use in target discovery, illustrated throughout with examples. Ideal for students and established biochemists, the book will also cover new technologies for probe discovery, new probe modalities, the new field of probes for RNA targets and the mature field of kinase chemical probes.

Proceedings of 13th International Conference and Exhibition on Nanomedicine and Pharmaceutical Nanotechnology 2017

Proceedings of 13th International Conference and Exhibition on Nanomedicine and Pharmaceutical Nanotechnology 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2017-07-18
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

July 24-25, 2017 Rome, Italy Key Topics : Pharmaceutical Nanotechnology, Novel Drug Delivery Technology, Nanomedicine and Drug Delivery, Nanotechnology for Pediatric Medicine, Nanotechnology in Preclinical and Clinical Development, Regulatory Guidance for Pharmaceutical Nanotechnology, Nanotechnology for Targeted Drug Delivery, Future Aspects of Pharmaceutical Nanotechnology, Recent Advances in Nanotechnology, Major Challenges in Nanotechnology, Pharmaceutical Companies and Markets, Business Opportunities in Nanotechnology, Nano Pharmaceuticals, Nanomedicines and Biomedical Applications,