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Personalized Health Systems For Cardiovascular Disease

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Personalized Health Systems for Cardiovascular Disease

Personalized Health Systems for Cardiovascular Disease Book
Author : Anna M. Bianchi,Jorge Henriques,Vicente Traves Salcedo
Publisher : Academic Press
Release : 2020-11-01
ISBN : 0128190663
Language : En, Es, Fr & De

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Book Description :

Personalized Health Systems for Cardiovascular Disease provides an integrated view of the problems related to p-health systems and is intended for researchers, developers, and designers in the field, with a focus on management of cardiovascular diseases. Biomedical engineers, physicians, and other professionals who operate in the health domain will benefit from the coverage of sensors, data transmission, signal processing, data analysis, home and mobile applications, and standards. Graduate and medical students will find a complete view of the manifold aspects of p-health, including technical problems with sensors and software, automatic evaluation, correct data interpretation, and legal and regulatory considerations. This book focuses on the development of technology used by people and patients in the management of their own health. New wearable and implantable devices allow continuous monitoring of chronic patients, with direct involvement of clinical centers and physicians. Also healthy people are more and more interested in keeping their own wellness under control, by adopting healthy lifestyles and identifying any early sign of risk. This is leading to personalized solutions via systems that are tailored to a specific patient's needs. However, many questions are still open when it comes to p-health systems: Which sensors and parameters should be used? Which software and analysis? When and how? How do you design an effective management plan for chronic pathologies such as cardiovascular diseases? What is useful feedback for the patient or for the clinician? And finally, what are the limits of this approach? What is the view of physicians? Provides an integrated approach to design and development of p-health systems, including sensors, analysis software, user interfaces, data transmission, and storage Covers standards and regulations on data privacy and security, plus safe design of devices Features case studies discussing the development of actual solutions in the biomedical engineering field Includes technical problems with sensors and software, automatic evaluation, correct data interpretation, and legal and regulatory considerations

Personalized and Precision Integrative Cardiovascular Medicine

Personalized and Precision Integrative Cardiovascular Medicine Book
Author : Houston
Publisher : LWW
Release : 2019-12-02
ISBN : 9781975115289
Language : En, Es, Fr & De

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Book Description :

Encompassing functional cardiology, integrative medicine, and metabolic medicine/cardiology, this unique reference offers an up-to-date, expert approach to heart health wellness and treating the diseased heart and blood vessels. It provides today's practitioners with insight into various treatment options and alternatives to pharmaceutical care and surgery, incorporating new scientific information on metabolic and integrative cardiovascular medicine from peer-reviewed articles, evidence-based medicine, and human clinical research as a foundation for practical clinical information. Covers functional cardiology, integrative medicine, and metabolic medicine/cardiology in an expert, practical manner - ideally suited for practitioners who already incorporate integrative approaches in their practice, as well as more traditional clinicians who want to learn more about this growing area. Reviews pathophysiology, vascular biology and vascular aging, nutrition supplements and food sensitivities, testing and cardiovascular disease, hypertension, dyslipidemia, congestive heart failure, CV genomics, pharmacotherapy, special populations, and more. Helps clinicians develop a comprehensive prevention, management, and treatment program to reduce the incidence of cardiovascular disease, targeting organ damage, morbidity, and mortality. Ideal for cardiologists, fellows, naturopathic, osteopathic and chiropractic physicians, primary care and internal medicine providers, physician assistants, and nurse practitioners. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Intelligent IoT Systems in Personalized Health Care

Intelligent IoT Systems in Personalized Health Care Book
Author : Arun Kumar Sangaiah,Subhas Chandra Mukhopadhyay
Publisher : Academic Press
Release : 2020-12-01
ISBN : 0128232048
Language : En, Es, Fr & De

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Book Description :

Intelligent IoT Systems in Personalized Health Care delivers a significant forum for the technical advancement of IoMT learning in parallel computing environments across biomedical engineering diversified domains and its applications. Pursuing an interdisciplinary approach, the book focuses on methods used to identify and acquire valid, potentially useful knowledge sources. The book presents novel, in-depth, fundamental research contributions from a methodological/application perspective to help readers understand the fusion of AI with IoT and its capabilities in solving a diverse range of problems for biomedical engineering and its real-world personalized health care applications. The book is well suited for researchers exploring the significance of IoT based architecture to perform predictive analytics of user activities in sustainable health. Presents novel, in-depth, fundamental research contributions from a methodological/application perspective to help readers understand the fusion of AI with IoT Illustrates state-of-the-art developments in new theories and applications of IoMT techniques as applied to parallel computing environments in biomedical engineering systems Presents concepts and technologies successfully used in the implementation of today's intelligent data-centric IoT systems and Edge-Cloud-Big data

Handbook of Medical and Healthcare Technologies

Handbook of Medical and Healthcare Technologies Book
Author : Borko Furht,Ankur Agarwal
Publisher : Springer Science & Business Media
Release : 2013-11-20
ISBN : 1461484952
Language : En, Es, Fr & De

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Book Description :

This book equips readers to understand a complex range of healthcare products that are used to diagnose, monitor, and treat diseases or medical conditions affecting humans. The first part of the book presents medical technologies such as medical information retrieval, tissue engineering techniques, 3D medical imaging, nanotechnology innovations in medicine, medical wireless sensor networks, and knowledge mining techniques in medicine. The second half of the book focuses on healthcare technologies including prediction hospital readmission risk, modeling e-health framework, personal Web in healthcare, security issues for medical records, and personalized services in healthcare. The contributors are leading world researchers who share their innovations, making this handbook the definitive resource on these topics. Handbook of Medical and Healthcare Technologies is intended for a wide audience including academicians, designers, developers, researchers and advanced-level students. It is also valuable for business managers, entrepreneurs, and investors within the medical and healthcare industries.

Informationweek

Informationweek Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Digital Personalized Health and Medicine

Digital Personalized Health and Medicine Book
Author : L.B. Pape-Haugaard,C. Lovis,I. Cort Madsen
Publisher : IOS Press
Release : 2020-06-17
ISBN : 1643680838
Language : En, Es, Fr & De

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Book Description :

Digital health and medical informatics have grown in importance in recent years, and have now become central to the provision of effective healthcare around the world. This book presents the proceedings of the 30th Medical Informatics Europe conference (MIE). This edition of the conference, hosted by the European Federation for Medical Informatics (EFMI) since the 1970s, was due to be held in Geneva, Switzerland in April 2020, but as a result of measures to prevent the spread of the Covid19 pandemic, the conference itself had to be cancelled. Nevertheless, because this collection of papers offers a wealth of knowledge and experience across the full spectrum of digital health and medicine, it was decided to publish the submissions accepted in the review process and confirmed by the Scientific Program Committee for publication, and these are published here as planned. The 232 papers are themed under 6 section headings: biomedical data, tools and methods; supporting care delivery; health and prevention; precision medicine and public health; human factors and citizen centered digital health; and ethics, legal and societal aspects. A 7th section deals with the Swiss personalized health network, and section 8 includes the 125 posters accepted for the conference. Offering an overview of current trends and developments in digital health and medical informatics, the book provides a valuable information resource for researchers and health practitioners alike.

Genome Based Therapeutics

Genome Based Therapeutics Book
Author : Institute of Medicine,Board on Health Sciences Policy,Roundtable on Translating Genomic-Based Research for Health
Publisher : National Academies Press
Release : 2012-11-21
ISBN : 0309260272
Language : En, Es, Fr & De

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Book Description :

The number of new drug approvals has remained reasonably steady for the past 50 years at around 20 to 30 per year, while at the same time the total spending on health-related research and development has tripled since 1990. There are many suspected causes for this trend, including increases in regulatory barriers, the rising costs of scientific inquiry, a decrease in research and development efficiency, the downstream effects of patient expirations on investment, and the lack of production models that have successfully incorporated new technology. Regardless, this trajectory is not economically sustainable for the businesses involved, and, in response, many companies are turning toward collaborative models of drug development, whether with other industrial firms, academia, or government. Introducing greater efficiency and knowledge into these new models and aligning incentives among participants may help to reverse the trends highlighted above, while producing more effective drugs in the process. Genome-Based Therapeutics explains that new technologies have the potential to open up avenues of development and to identify new drug targets to pursue. Specifically, improved validation of gene-disease associations through genomics research has the potential to revolutionize drug production and lower development costs. Genetic information has helped developers by increasing their understanding of the mechanisms of disease as well as individual patients' reactions to their medications. There is a need to identify the success factors for the various models that are being developed, whether they are industry-led, academia-led, or collaborations between the two. Genome-Based Therapeutics summarizes a workshop that was held on March 21, 2012, titled New Paradigms in Drug Discovery: How Genomic Data Are Being Used to Revolutionize the Drug Discovery and Development Process. At this workshop the goal was to examine the general approaches being used to apply successes achieved so far, and the challenges ahead.

Healthcare Overview

Healthcare Overview Book
Author : Vincenzo Costigliola
Publisher : Springer Science & Business Media
Release : 2012-11-06
ISBN : 9400746024
Language : En, Es, Fr & De

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Book Description :

In healthcare, the realisation of an optimistic prognosis against pessimistic ones depends on current innovations in diagnostic and cost-effective treatment approaches being widely adopted in clinical practice. Utilisation of advanced early and predictive diagnostics, targeted prevention and personalised medical approaches could enable the elderly subpopulation to reach the 100-year age limit in good physical and mental health, as actively contributing members of society. This task requires intelligent political regulations and creation of new guidelines to advance current healthcare systems. In this book, we will collect contributions from several geopolitical regions of Europe, Asia and USA that provide expert opinion on healthcare organisation and outlook as well as economical aspects of personalised medicine.

Health Risk Appraisal

Health Risk Appraisal Book
Author : Anonim
Publisher : Unknown
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Health Risk Appraisal book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Wearable Ehealth Systems for Personalised Health Management

Wearable Ehealth Systems for Personalised Health Management Book
Author : Andreas Lymberis
Publisher : IOS Press
Release : 2004-01-01
ISBN : 1586034499
Language : En, Es, Fr & De

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Book Description :

This book consists of papers describing developments and trends all over the world in the areas of smart wearable monitoring and diagnostic systems, smart treatment systems, biomedical clothing and smart fibres and fabrics.

Primary Care and the Public s Health

Primary Care and the Public s Health Book
Author : Nancy Milio
Publisher : Free Press
Release : 1983
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Patient Specific Modeling of the Cardiovascular System

Patient Specific Modeling of the Cardiovascular System Book
Author : Roy C.P. Kerckhoffs
Publisher : Springer Science & Business Media
Release : 2010-09-03
ISBN : 9781441966919
Language : En, Es, Fr & De

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Book Description :

Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 in this volume, by Speelman et al. , deals with the very difficult problem of trying to predict whether and when an abdominal aortic aneurysm might burst. This requires automated segmentation of the vascular geometry from magnetic re- nance images and finite element analysis of wall stress using large deformation elasticity theory applied to the geometric model created from the segmentation. The time-varying normal and shear stress acting on the arterial wall is estimated from the arterial pressure and flow distributions. Thrombus formation is identified as a potentially important contributor to changed material properties of the arterial wall. Understanding how the wall adapts and remodels its material properties in the face of changes in both the stress loading and blood constituents associated with infl- matory processes (IL6, CRP, MMPs, etc.

Textbook of Personalized Medicine

Textbook of Personalized Medicine Book
Author : Kewal K. Jain
Publisher : Springer Science & Business Media
Release : 2009-08-29
ISBN : 9781441907691
Language : En, Es, Fr & De

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Book Description :

Personalized medicine, which simply means selection of treatment best suited for an individual, involves integration and translation of several new technologies in clinical care of patients. The scope is much broader than indicated by the term genomic medicine because many non-genomic factors are taken into consideration in developing personalized medicine. Basic technologies for personalized medicine, of which molecular diagnostics has the biggest share, are mentioned briefly and appropriate references are given for further information. Commercial aspects are discussed briefly in a chapter and detailed analysis of markets and companies involved in personalized medicine is presented in a special report on this topic. There is increasing interest in personalized medicine. Considerable advances have taken place in molecular biology and biotechnology to make personalized medicine a viable option, but some misconceptions still exist, both in the academic and commercial sectors. There is lack of a suitable source of information that provides both the fundamentals as well as applications of personalized medicine. As the latest version of the first monograph on personalized medicine published in 1998, this volume, Textbook of Personalized Medicine, summarizes the author’s efforts during the past decade, as well as reviews selected studies done during this period in a readable format for the physicians and scientists. It is hoped that physicians, pharmacists, scientists and interested lay readers with basic scientific knowledge will find this book useful.

Advanced Biosensors for Health Care Applications

Advanced Biosensors for Health Care Applications Book
Author : Dr. Inamuddin,Raju Khan,Ali Mohammad,Abdullah M. Asiri
Publisher : Elsevier
Release : 2019-06-15
ISBN : 0128165227
Language : En, Es, Fr & De

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Book Description :

Advanced Biosensors for Health Care Applications highlights the different types of prognostic and diagnostic biomarkers associated with cancer, diabetes, Alzheimer's disease, brain and retinal diseases, cardiovascular diseases, bacterial infections, as well as various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of these diseases. Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches. This book outlines the need of novel strategies for developing new systems to retrieve health information of patients in real time. It explores the potential of nano-multidisciplinary science in the design and development of smart sensing technology using micro-nanoelectrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy, that is, FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-Chip (LOC), for diagnostics and personalized health-care monitoring. It is a useful handbook for specialists in biotechnology and biochemical engineering. Describes advanced nanomaterials for biosensor applications Relates the properties of available nanomaterials to specific biomarkers applications Includes diagnosis and electrochemical studies based on biosensors Explores the potential of nano-multidisciplinary science to design and develop smart sensing technologies Describes novel strategies for developing a new class of assay systems to retrieve the desired health information

American Journal of Public Health

American Journal of Public Health Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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State Health Plan

State Health Plan Book
Author : Statewide Health Coordinating Council (Ill.)
Publisher : Unknown
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download State Health Plan book written by Statewide Health Coordinating Council (Ill.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Proposed State Health Plan

Proposed State Health Plan Book
Author : Statewide Health Coordinating Council (Ill.)
Publisher : Unknown
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Proposed State Health Plan book written by Statewide Health Coordinating Council (Ill.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Health Monitoring Systems

Health Monitoring Systems Book
Author : Rajarshi Gupta,Dwaipayan Biswas
Publisher : CRC Press
Release : 2019-11-21
ISBN : 0429532555
Language : En, Es, Fr & De

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Book Description :

Remote health monitoring using wearable sensors is an important research area involving several key steps: physiological parameter sensing and data acquisition, data analysis, data security, data transmission to caregivers, and clinical intervention, all of which play a significant role to form a closed loop system. Subject-specific behavioral and clinical traits, coupled with individual physiological differences, necessitate a personalized healthcare delivery model for around-the-clock monitoring within the home environment. Cardiovascular disease monitoring is an illustrative application domain where research has been instrumental in enabling a personalized closed-loop monitoring system, which has been showcased in this book. Health Monitoring Systems: An Enabling Technology for Patient Care provides a holistic overview of state-of-the-art monitoring systems facilitated by Internet of Things (IoT) technology. The book lists out the details on biomedical signal acquisition, processing, and data security, the fundamental building blocks towards an ambulatory health monitoring infrastructure. The fundamentals have been complimented with other relevant topics including applications which provide an in-depth view on remote health monitoring systems. Key Features: Presents examples of state-of-the-art health monitoring systems using IoT infrastructure Covers the full spectrum of physiological sensing, data acquisition, processing, and data security Provides relevant example applications demonstrating the benefits of technological advancements aiding disease prognosis This book serves as a beginner’s guide for engineering students of electrical and computer science, practicing engineers, researchers, and scientists who are interested in having an overview of pervasive health monitoring systems using body-worn sensors operating outside the hospital environment. It could also be recommended as a reference for a graduate or master’s level course on biomedical instrumentation and signal processing.

A Systems Medicine Approach to Multimorbidity Towards Personalised Care for Patients with Chronic Obstructive Pulmonary Disease

A Systems Medicine Approach to Multimorbidity  Towards Personalised Care for Patients with Chronic Obstructive Pulmonary Disease Book
Author : Ákos Tényi
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

BACKGROUND: Multimorbidity (i.e. the presence of more than one chronic disease in the same patient) and comorbidity (i.e. the presence of more than one chronic disease in the presence of an index disease) are main sources of dysfunction in chronic patients and avoidable costs in conventional health systems worldwide. By affecting a majority of elderly population worldwide, multimorbidity prompts the need for revisiting the single disease approach followed by contemporary clinical practice and elaborate strategies that target shared mechanisms of associated diseases with the potential of preventing, decelerating or even halting multimorbid disease progression. However, our current understanding on disease interactions is rather limited, and although many disorders have been associated based on their shared molecular traits and their observed co-occurrence in different populations, no comprehensive approach has been outlined to translate this knowledge into clinical practice. The advent of novel measurement technologies (e.g. omics) and recent initiatives on digital health (e.g. registries, electronic health records) are facilitating access to an enormous amount of patient-related information from whole populations to molecular levels. State-of-the art computational models and machine learning tools demonstrate high potential for health prediction and together with systems biology are shaping the practicalities of systems medicine. Given the extremely long and expensive bench to clinics cycles of the biomedical sector, systems medicine promises a fast track approach where scientific evidence support clinical care, while simultaneously collected insights from daily clinical practice promote new scientific discoveries and optimize healthcare. The PhD thesis aims to explore multimorbidity from a systems medicine perspective on the concrete and practical use case of chronic obstructive pulmonary disease (COPD). COPD constitutes an ideal use case due to several factors, including: i) its high impact on healthcare and its ever-increasing burden; ii) its heterogeneous disease manifestations, and progress, often involving extra-pulmonary effects, including highly prevalent comorbidities (e.g. type 2 diabetes mellitus, cardiovascular disorders, anxiety-depression and lung cancer); and, iii) its well described systemic effects that are suggested associations with comorbidities in terms of underlying mechanisms. HYPOTHESIS: The central hypothesis of the PhD thesis builds on the emerging biological evidence that clustering of comorbid conditions, a phenomenon seen in complex chronic patients, could be due to shared abnormalities in relevant biological pathways (i.e. bioenergetics, inflammation and tissue remodelling). It is assumed that a systems understanding of the patient conditions may help to uncover the molecular mechanisms and lead to the design of preventive and targeted therapeutic strategies aiming at modulating patient prognosis. The PhD thesis focuses on non-pulmonary phenomena of COPD; that is, systemic effects and comorbidities, often observed in patients with COPD as a paradigm of complex chronic disease. OBJECTIVES: The general objective of the PhD thesis is threefold: i) to investigate molecular disturbances at body systems level that may lead to a better understanding of characteristic systemic effects and comorbidities of patients with COPD; ii) to analyse population level patterns of COPD comorbidities and investigate their role in the health risk of patients with COPD; and, iii) to explore technological strategies and tools that facilitate the transfer of the collected knowledge on comorbidity into clinical practice. MAIN FINDINGS: Firstly, the PhD thesis introduced a novel knowledge management tool for targeted molecular analysis of underlying disease mechanisms of skeletal muscle dysfunction in patients with COPD. Second, a network analysis approach was outlined to further study this systemic effect, as well as the causes of abnormal adaptation of COPD muscle to exercise training. Furthermore, this work together with three other studies also aimed to reveal the general underlying causes of comorbidity clustering in COPD, using different modelling approaches. Overarching outcome of these studies indicates abnormalities in the complex co-regulation of core biological pathways (i.e. bioenergetics, inflammation, oxidative stress and tissue remodelling) both on muscle and body systems level (blood, lung), which paves the way for the development of novel pharmacological and non-pharmacological preventive interventions on non- pulmonary phenomena in patients with COPD. Furthermore, results indicated strong relation of muscle related dysregulations to aerobic capacity, in opposed to pulmonary severity of COPD. These findings have far reaching potential in COPD care, starting from defining the need for better characterization of exercise performance in the clinic practice and the promotion of physical activity from early stages of the disease. This PhD thesis also generated outcomes with respect to the risk of multimorbidity in patients with COPD using a population health approach. The thesis validated that patients with COPD are in increased risk to co-occur with other diseases compared to non-COPD patients, regardless of the population and healthcare system specificities of different regions (i.e. Catalonia, US). These findings indicated the potential role of multimorbidity as a risk factor for COPD, that was evaluated in the PhD thesis by constructing health risk assessment models to predict unexpected medical events in patients with COPD. The promising performance of the models and the prominent role of multimorbidity in these models presented a powerful argument for its role in clinical staging of the disease and their potential in clinical decision support. CONCLUSIONS: The PhD thesis achieved main points of the general objectives, namely: i) to perform a systems analysis of patients with COPD by investigating molecular disturbances at body systems level leading to a better understanding of characteristic systemic effects and comorbidities of patient with COPD; ii) to analyse population level patterns of COPD comorbidities and investigate their role in the health risk of patients with COPD; and iii) to explore technological strategies and tools that facilitate the transfer of the collected knowledge on comorbidity into clinical practice. Accordingly, the following conclusions arise: 1.Non-pulmonary manifestations in patients with Chronic Obstructive Pulmonary Disease (COPD) have a major negative impact on: highly relevant clinical events, use of healthcare resources and prognosis. Accordingly, the following indications were made: a.Actionable insights on non-pulmonary phenomena should be included in the clinical staging of these patients in an operational manner. b.Management of patients with COPD should be revisited to incorporate an integrative approach to non-pulmonary phenomena. c.Innovative cost-effective interventions,

SCLC

SCLC Book
Author : Anonim
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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