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Peptide And Protein Delivery

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Peptide and Protein Delivery

Peptide and Protein Delivery Book
Author : Chris Van Der Walle
Publisher : Academic Press
Release : 2011-05-12
ISBN : 9780123849366
Language : En, Es, Fr & De

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Book Description :

The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell biology, immunology, chemistry and biotechnology fields will find this publication invaluable for peptide and protein laboratory research. Discusses the most recent data, ideas and concepts Presents case studies and an industrial perspective Details information from the molecular level to bioprocessing Thought provoking, for the novice to the specialist Timely, for today's biopharmaceuticals market

Protein and Peptide Nanoparticles for Drug Delivery

Protein and Peptide Nanoparticles for Drug Delivery Book
Author : Anonim
Publisher : Academic Press
Release : 2015-03-26
ISBN : 012802870X
Language : En, Es, Fr & De

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Book Description :

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in a wide bioscience area Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Inhalation Delivery of Therapeutic Peptides and Proteins

Inhalation Delivery of Therapeutic Peptides and Proteins Book
Author : Akwete Adjei
Publisher : CRC Press
Release : 1997-07-08
ISBN : 9780824797805
Language : En, Es, Fr & De

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Book Description :

This exhaustive reference-the first book of its kind to describe in detail the functionality of the human respiratory tract and its impact on both local and systemic delivery of biotherapeutic and macromolecular drug systems-offers comprehensive analyses of peptide and protein drug delivery through the lung. Summarizes over 130 patents granted worldwide on alternative systems for pulmonary delivery of therapeutic drugs-especially peptides and proteins! Examining macromolecular drug delivery as an efficient, patient-friendly, and cost-effective method of treatment, Inhalation Delivery of Therapeutic Peptides and Proteins discusses airway physiology and biomechanics the pharmaceutical concerns associated with the respiratory tract as a viable port of drug entry to the body key peptide drugs under development and in use to treat local lung disease, including cyclosporines, interferons, antitrypsins, protease inhibitors, and deoxyribonucleases the systemic delivery of peptide and protein drugs using fine-particle technology gene therapy employing gene delivery through the airways new developments in pulmonary delivery technologies emphasizing inhaled peptide and protein drugs guidelines for the successful introduction of peptide inhalation aerosol products into the marketplace and much more!

Peptide and Protein Drug Delivery

Peptide and Protein Drug Delivery Book
Author : Vincent Lee
Publisher : CRC Press
Release : 1990-11-19
ISBN : 9780824778965
Language : En, Es, Fr & De

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Book Description :

This reference/text covers fundamentals of peptide and protein drug delivery, including such considerations as synthesis, physical chemistry and biochemistry, analysis, proteolytic and transport constraints, pharmacokinetics, and pharmacodynamics; bioavailability from routes of administration, detai

Trends and Future Perspectives in Peptide and Protein Drug Delivery

Trends and Future Perspectives in Peptide and Protein Drug Delivery Book
Author : Vincent Lee
Publisher : CRC Press
Release : 1995-02-01
ISBN : 9783718656417
Language : En, Es, Fr & De

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Book Description :

Download Trends and Future Perspectives in Peptide and Protein Drug Delivery book written by Vincent Lee, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Delivery Systems for Peptide Drugs

Delivery Systems for Peptide Drugs Book
Author : S.S. Davis,Lisbeth Illum,E. Tomlinson
Publisher : Springer Science & Business Media
Release : 2013-11-11
ISBN : 1475799608
Language : En, Es, Fr & De

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Book Description :

Recent years have seen enormous advances in the field of protein and peptide engineering and a greater understanding in the way in which biological response modifiers function in the body. It is now possible through the use of recombinant DNA techniques, or by solid phase protein synthesis, to produce significant quantities of a wide variety of regulatory agents that are therapeutically applicable. The list of these response modifiers expands almost daily to include interferons, macrophage activation factors, neuropeptides and agents that may have potential in cardiovascular disease, inflammation, contraception etc. Prospects to use some of these materials in medicine have reached the stage where products have either been approved by regulatory authorities or are the subject of applications as investigatory drugs or as new therapeutic agents. In some uses the pertinent agent will be administered on an acute basis in the form of a simple injection, as, for example, the use of a tissue plasminogen activator for the treatment of coronary infarct. In other cases regulatory proteins and peptides are indicated for chronic therapy and here they will need to be administered by an appropriate delivery system. Unfortunately, the research on delivery systems for peptides and proteins has not kept pace with the rapid progress in biotechnology and, consequently, there are presently few systems that are entirely appropriate for the administration of macromolecular drugs according to complex dosage regimens, (eg intermittent and pulsed therapy). Furthermore essential pharmacokinetic and pharmacodynamic data may be missing.

Biological Barriers to Protein Delivery

Biological Barriers to Protein Delivery Book
Author : Kenneth L. Andus,Thomas L. Raub
Publisher : Springer
Release : 2012-10-24
ISBN : 9781461362562
Language : En, Es, Fr & De

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Book Description :

In response to the tremendous increase in the number of protein and peptide drugs, this treatise critically reviews transport and metabolism mechanisms relating to the delivery of endogenous and recombinant proteins to mammalian organs, tissues, and cells. It will promote fruitful collaboration among academic and industrial scientists in the fields of pharmacology, cell biology, biochemistry, physiology, and immunology.

Therapeutic Peptides and Proteins

Therapeutic Peptides and Proteins Book
Author : Ajay K. Banga
Publisher : CRC Press
Release : 2005-09-14
ISBN : 1420039830
Language : En, Es, Fr & De

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Book Description :

Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there were only 19 biotechology medicines on the market. Currently there are more than 100, with at least 400 more in various stages of development. That alone would be grounds for a new edition. Add to that the fact that it is still difficult to find up

Therapeutic Peptides and Proteins

Therapeutic Peptides and Proteins Book
Author : Ajay K. Banga
Publisher : CRC Press
Release : 2015-04-23
ISBN : 1466566078
Language : En, Es, Fr & De

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Book Description :

There are more than 500 biopharmaceuticals on the market, including more than 200 therapeutic proteins, making biologics the fastest growing sector in the biopharmaceutical market. These products include more than 40 monoclonal antibodies, for indications ranging from treatment or mitigation of various types of cancer to rheumatoid arthritis. The clinical application of these therapeutic peptides and proteins is limited by several problems, such as lack of physical and chemical stability or the lack of desirable attributes for adequate absorption or distribution. Thus, as these therapeutic peptides and proteins are made available, it will be essential to formulate these drugs into safe, stable, and efficacious delivery systems. The pharmaceutical scientist involved in this effort needs to call upon the knowledge of several disciplines, such as pharmaceutics, medicinal chemistry, biochemistry, microbiology, and chemical engineering and needs to keep abreast with the latest research in the published literature. Therapeutic Peptides and Proteins: Formulation, Processing, and Delivery Systems, Third Edition provides a comprehensive overview of the field for scientists in industry and academia and for students, while also providing practical information on the challenges facing the formulation and delivery aspects of these unique macromolecules. In particular, the book: Explains how recombinant DNA techniques now allow us to produce therapeutic proteins in a commercially viable form Discusses the physical and chemical pathways of peptide and protein degradation Includes a detailed discussion of protein formulation and lyophilization Overviews the pharmacokinetic aspects of therapeutic peptides and proteins and discusses controlled delivery systems for parenteral administration, including microsphere formulations Discusses research progress on oral, transdermal, mucosal, and topical delivery systems discusses transdermal and topical delivery

Recent Advances in Peptide and Protein Delivery

Recent Advances in Peptide and Protein Delivery Book
Author : Anonim
Publisher : Unknown
Release : 1998
ISBN : 9782864111139
Language : En, Es, Fr & De

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Book Description :

Download Recent Advances in Peptide and Protein Delivery book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Proteins and Peptides

Proteins and Peptides Book
Author : Randall J. Mrsny,Ann Daugherty
Publisher : CRC Press
Release : 2009-10-19
ISBN : 1420078070
Language : En, Es, Fr & De

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Book Description :

Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate. Proteins and Peptides is

Therapeutic Proteins and Peptides

Therapeutic Proteins and Peptides Book
Author : Anonim
Publisher : Academic Press
Release : 2018-04-18
ISBN : 012814341X
Language : En, Es, Fr & De

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Book Description :

Therapeutic Proteins and Peptides, Volume 112 in an ongoing series promotes further research in the discovery of new therapeutic targets that can be affected by therapeutic proteins and peptides to cure or manage symptoms of human diseases, with this release focusing on the Rational Design of Stable Liquid Formulations of Biopharmaceuticals, Formulation strategies for peptides, proteins and antibodies using nanotechnology, the Solution structural dynamics of therapeutic peptides and their adsorption on plasmonic nanoparticles, Enzymatic approaches of protein-polymer conjugation, Chimeric small antibody fragments as a strategy to deliver therapeutic payloads, Smart cell-penetrating peptide-based techniques for cytoplasmic delivery of therapeutic macromolecules, and more. Describes advances in the discovery and application of therapeutic proteins/peptides which allow better targeting to the site of treatment and cause fewer adverse effects when compared to chemical compounds used for disease treatment Targeted to a very wide audience of specialists, researchers and students Written by well-renown authorities in their field Includes a number of high quality illustrations, figures and tables

Peptide and Protein Drug Delivery

Peptide and Protein Drug Delivery Book
Author : Vincent H. L. Lee
Publisher : Marcel Dekker Incorporated
Release : 1979-11-01
ISBN : 9780824702977
Language : En, Es, Fr & De

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Book Description :

Download Peptide and Protein Drug Delivery book written by Vincent H. L. Lee, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Protein Formulation and Delivery Second Edition

Protein Formulation and Delivery  Second Edition Book
Author : Eugene J. McNally,Eugene McNally,Jayne E. Hastedt
Publisher : CRC Press
Release : 2007-10-26
ISBN : 9780849379529
Language : En, Es, Fr & De

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Book Description :

This title is intended to assist pharmaceutical scientists in the development of stable protein formulations during the early stages of the product development process, providing a comprehensive review of mechanisms and causes of protein instability in formulation development, coverage of accelerated stability testing methods and relevant analytical methods, and an overview of the drug substance manufacturing process. Preformulation and the development of traditional solutions and lyophilized formulations frequently used for intravenous delivery and non-traditional formulations are also addressed. Because many developments in the field have emerged since the publication of the First Edition, this Second Edition addresses important new patient-friendly developments in the field, such as formulation for implantable devices, needle-free formulation and delivery approaches, and oral delivery of proteins.

Biological Barriers to Protein Delivery

Biological Barriers to Protein Delivery Book
Author : Kenneth L. Andus,Thomas L. Raub
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461528984
Language : En, Es, Fr & De

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Book Description :

In response to the tremendous increase in the number of protein and peptide drugs, this treatise critically reviews transport and metabolism mechanisms relating to the delivery of endogenous and recombinant proteins to mammalian organs, tissues, and cells. It will promote fruitful collaboration among academic and industrial scientists in the fields of pharmacology, cell biology, biochemistry, physiology, and immunology.

Peptide and Protein Drug Delivery

Peptide and Protein Drug Delivery Book
Author : Hani H. Sarraf,King's College London. Chelsea Department of Pharmacy
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Peptide and Protein Drug Delivery book written by Hani H. Sarraf,King's College London. Chelsea Department of Pharmacy, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Novel Peptide Protein Delivery System Targeting ErbB2 Overexpressing Breast Cancer Cells

Novel Peptide Protein Delivery System Targeting ErbB2 Overexpressing Breast Cancer Cells Book
Author : Anonim
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

It has been well recognized that the next frontier in molecular medicine is the delivery of therapeutics. Among the biological therapeutics, peptides/proteins are especially difficult and challenging to deliver. A peptide sequence localized within a 13-amino acid domain of Tat (named "penetratin"), when linked to other peptides or proteins, was able to carry attached peptide or protein into the cells when they were added to cell culture medium. We hypothesized that the unique property of "penetratin" can be utilized for delivery of therapeutic peptides/proteins. It should be noted that after the funding of this Idea Award, a report published in Science by Steven Dowdy's laboratory demonstrated that "penetratin" can deliver functional beta-galactosidase protein (120 kD) to all tissues in mice.

Peptide and Protein Drug Delivery

Peptide and Protein Drug Delivery Book
Author : Sven Frøkjær,Lona Christrup,Povl Krogsgaard-Larsen
Publisher : Munksgaard International Publishers
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Peptide and Protein Drug Delivery book written by Sven Frøkjær,Lona Christrup,Povl Krogsgaard-Larsen, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Protein Peptide Drug Delivery 3

Protein   Peptide Drug Delivery 3 Book
Author : Anonim
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Protein Peptide Drug Delivery 3 book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.