Pediatric Transplant And Oncology Infectious Diseases

Book Description :

As the number and types of pediatric transplants increase and the complexity of chemotherapy regimens continues to evolve, there is a greater need for authoritative guidance, clinically actionable strategies, and easy-to-find information in the challenging area of immunocompromised pediatric patients. Pediatric Transplant and Oncology Infectious Diseases offers up-to-date, targeted coverage of this complex field, compiled by world-renowned editors and authors into one convenient volume. Covers the must-know principles for diagnosing and managing opportunistic infections in immunocompromised populations and detailed aspects of their care – information not specifically covered in pediatric infectious disease textbooks or pediatric oncology books. Features algorithms in every chapter that provide visual, accessible overviews of treatment protocols. Discusses key topics such as microbiome implications in transplantation and oncology, antimicrobial resistant Gram-negative bacteria, EBV-associated post-transplant lymphoproliferative disorders, and many others. Offers well-referenced, evidence-based content throughout, with targeted suggested readings provided.

Book Description :

As the number and types of pediatric transplants increase and the complexity of chemotherapy regimens continues to evolve, there is a greater need for authoritative guidance, clinically actionable strategies, and easy-to-find information in the challenging area of immunocompromised pediatric patients. Pediatric Transplant and Oncology Infectious Diseases offers up-to-date, targeted coverage of this complex field, compiled by world-renowned editors and authors into one convenient volume. Covers the must-know principles for diagnosing and managing opportunistic infections in immunocompromised populations and detailed aspects of their care - information not specifically covered in pediatric infectious disease textbooks or pediatric oncology books. Features algorithms in every chapter that provide visual, accessible overviews of treatment protocols. Discusses key topics such as microbiome implications in transplantation and oncology, antimicrobial resistant Gram-negative bacteria, EBV-associated post-transplant lymphoproliferative disorders, and many others. Offers well-referenced, evidence-based content throughout, with targeted suggested readings provided. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Book Description :

The field of transplant medicine has evolved significantly since the first kidney transplant was performed in 1954. Innovations in transplant immunosuppression have lowered the risk of organ rejection so that infectious complications are now the leading cause of hospitalization and mortality after solid organ transplant. Infection is also cited as the leading cause of non-relapse mortality after stem cell transplantation. As transplant centers have recognized the importance of transplant specific expertise in patient outcomes, the field of transplant infectious diseases has expanded into a recognized and highly valued subspecialty. International growth in solid organ and stem cell transplantation has outpaced access to such expertise, with some centers employing microbiology laboratory directors and transplant nephrologists as their lead infectious diseases consultants. This has been a particular challenge as the use of novel immunosuppressive regimens in new geographic and immigrant populations have fueled the emergence of new infection syndromes, with the initial presentation sometimes occurring in this most vulnerable patient population. This digital-first book is designed to meet the needs of practitioners engaged in transplant infectious disease practice who need more depth than they are able to find in UpToDate. It provides an overview of emerging infectious disease challenges with clinically relevant information regarding the epidemiology, diagnosis, management, and prevention of infections in solid organ and stem cell transplant recipients. Each chapter focuses on a clinical syndrome or pathogen with new or emerging implications for transplant patients. Given the rapidly evolving nature of emerging infections and topics in transplant infections, no resource has been published on these increasingly notorious issues; this this text is written by top, global experts who regularly update the material to ensure that readers will always have access to the most cutting edge material available. The editorial team consists of three experienced leaders in the field, all of whom have a strong record of scholarship and publication, as well as an international reputation. All three have focused their academic careers on emerging infectious diseases in transplantation, including a current and a past president of various infectious diseases and transplantation societies. The editors are also experienced reviewers and authors who have collaborated on multiple previous projects. All are committed to this project as a unique opportunity to make an important contribution to their field.

Book Description :

This comprehensive volume provides a platform from which both major and minor infectious diseases related issues are addressed in-depth among this highly susceptible population. The book begins with an overview of infections in various modalities. This is followed by chapters on clinical disorders, etiologic agents, therapeutics, and infection prevention. Chapters include easy-to-follow figures and tables, radiologic images, and pictorial demonstrations of various disease states to familiarize and reacquaint the transplant clinicians and surgeons in practice and training, and those belonging to subspecialties providing supportive care for these patients. Discussions to enumerate the noninfectious causes that mimic infectious diseases; clinical relevance and effective utility of existing and emerging diagnostic tools are presented throughout the book. Authored by leaders in their fields, this book is the go-to reference for management of patients undergoing hematopoietic and solid organ transplantation.

Book Description :

This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Book Description :

Pediatric Solid Organ Transplantation is acomprehensive and succinct text on all aspects of pediatric solidorgan transplantation. It provides a ready source of reference, toboth the basic science and organ specific surgical technique andafter care. This second edition has been extensively updated inlight of recent developments in this rapidly advancing area. The only textbook devoted to the field of pediatrictransplantation A definitive reference for all those interested in improvingthe care and quality of life of children undergoing solid organtransplantation Section on immunosuppression has been expanded by four chaptersto include sections on; - mechanisms of action - therapies for the sensitized patient - post-transplant lymphoproliferative disorders - organ toxicities of immunosuppressive therapy A new section has been added on the many topics related toquality of life that effect survivors of pediatrictransplantation International editorial and contributor team represents a widegeographical range and contains both recognized leaders andemerging experts Whether you are an established sub-specialist in pediatrictransplantation, a transplant surgeon, or a pediatric specialist ina related area, this book will answer all your questions about careof the pediatric patient before, during, and aftertransplantation.

Book Description :

The evolution of Antimicrobial Resistance is outpacing the ability to create novel antibiotics, which is proving to be a global problem in the fact of climate change, population growth, demographic shifts toward aging populations, emerging infections, and other crises. Therefore, clinicians are forced to use the existing antimicrobials more responsibly to preserve their longevity for generations to come. In a parallel vein, there has been a recent regulatory acknowledgement of the importance of prudent antimicrobial prescribing, mandating the implementation of Antimicrobial Stewardship across all healthcare settings. This is harder to manage in a non-traditional setting, which include long-term care facilities, outpatient care clinics, urgent care centers, and others. Given the trends in patient care in these settings—particularly where the aging community is concerned—this is proving to be a growing problem. This is troublesome even for spaces that have university and large hospital affiliations. There is a plethora of data describing the implementation and outcomes of Antimicrobial Stewardship Programs in acute-care hospitals with open-access, evidence-based guidelines endorsed by the Infectious Diseases Society of America. However, non-traditional settings often find themselves struggling to implement the same practices and procedures due to their unique needs and limited resources. There may be variability in access to resources, applicability, and patient-type. This book seeks to inform those in non-traditional healthcare settings on the principles, practice, and outcomes of Antimicrobial Stewardship Programs to improve patient care across all settings. The text begins by unpacking Antimicrobial Stewardship in nontraditional settings then covers specific environments, including long-term care facilities, outpatient clinics, and emergency departments. The text also covers special topics, including veterinary medicine, HIV, oncology, and immunocompromised patients, pediatrics, neonates, transplant, and critical care patients.

Book Description :

The book provides a comprehensive and up-to-date overview of pediatric ENT infections. It brings together the experience of authors from more than 30 countries and aims to provide a broader understanding of the prevention and treatment of infectious diseases in children, that will likely lead to improve their health globally. In addition to new infections like COVID-19, the work reviews the latest treatments modalities. The list of topics ranges from basic to very advanced and the book will be therefore an invaluable resource for ENT and pediatrics trainees and students, as well as for experienced practitioners in these fields.

Book Description :

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Book Description :

Congenital and Acquired Bone Marrow Failure is a comprehensive guide to congenital and acquired bone marrow failure in adult and pediatric patients. Chapters are divided into two sections, acquired aplastic anemia and inherited bone marrow failure syndromes. Content ranges from the basic, to the translational, and from the epidemiology of acquired aplastic anemia and telomere biology, to the management, treatment, and supportive care of pediatric, adult, and geriatric patients. Contributors are world leading experts in the field of bone marrow failure. The book is required reading for residents, fellows, clinicians, and researchers across hematology, oncology, pathology, bone marrow transplantation, pediatrics, and internal medicine. Provides an overview of all congenital and acquired bone marrow failure syndromes Focuses on the molecular pathogenesis, clinical manifestation and diagnosis, laboratory features, and treatment of each disease within the syndromes Features the area of supportive care which is a topic of great interest to infectious disease physicians and those involved in transfusion services

Book Description :

Infection in the cancer patient is extremely common, either precipitated by the cancer itself or by the cancer therapies. Virtually all cancer patients develop an infection during their illness, often life-threatening and requiring urgent treatment. This book decribes the presentation and management of all infections met by the clinician.

Book Description :

This book focuses on the epidemiology, diagnosis and management of Healthcare-Associated Infections (HAIs) in children. Unlike similar texts, this book details both the general principles involved in HAIs and infection prevention and also provides a problem-oriented approach, more precisely meeting the needs of a clinician at the bedside. Importantly, included in this text are discussions on medical device-related infections in children. The book is divided into three principle sections: 1) basic principles of infection control and prevention, 2) major infectious syndromes and 3) infections in vulnerable hosts. Each chapter covers the epidemiology, microbiology, clinical features, diagnosis, medical management and prevention of the disease entity of interest. Written by experts in the field, chapters are evidenced-based, drawing from the published medical literature as well as from clinical practice guidelines. Richly illustrated with tables, figures and algorithms, the book is designed to assist in the evaluation and management of these often complex patients. Healthcare-Associated Infections in Children is a valuable resource for infectious disease specialists, intensivists, neonatologists, surgeons, oncologists, infection preventionists, hospitalists, nurses, and all medical professionals treating children who are susceptible to HAIs.

Book Description :

Staying true to the unique, problem-oriented approach of Dr. Hugh Moffet’s previous editions, the fifth edition of Moffet’s Pediatric Infectious Diseases walks the reader step by step through diagnosis and management using a signs and symptoms approach. This patient-oriented structure leads to a logical development of a differential diagnosis and evaluation and treatment plan, offering clear steps to confirm the diagnosis and provide appropriate therapy.

Book Description :

This volume provides a concise yet comprehensive overview of patient safety issues and quality improvement for the pediatric hematology/oncology/stem cell transplant practice. The book reviews patient safety in complex healthcare delivery systems, delineates the various safety issues affecting pediatric hematology/oncology patients, and discusses quality improvement methods and improvement science that allow the reader to implement and sustain change in their home institution. The text also explores mechanisms to measure quality and safety outcomes, allowing the provider to implement proven processes shown to minimize harm to patients. Written by experts in the field, Patient Safety and Quality in Pediatric Hematology/Oncology and Stem Cell Transplantation is a valuable resource for healthcare professionals treating pediatric hematology, oncology and stem cell transplant patients.

Book Description :

Comprehensive in scope, yet concise and easy to manage, Principles and Practice of Pediatric Infectious Diseases, 6th Edition, by Drs. Sarah S. Long, Charles G. Prober, Marc Fischer, and new editor David Kimberlin, is your go-to resource for authoritative information on infectious diseases in children and adolescents. A veritable "who's who" of global authorities provides the practical knowledge you need to understand, diagnose, and manage almost any pediatric infectious disease you may encounter. Covers the latest aspects of the COVID-19 pandemic, including manifestations, diagnosis, management, and prevention of SARS-CoV-2 infection. Features an easy-access format with high-yield information boxes, highlighted key points, and an abundance of detailed illustrations and at-a-glance tables. Allows quick look-up by clinical presentation, pathogen, or type of host. Highlights expanding antimicrobial resistance patterns and new therapies for viral and fungal infections and resistant bacterial infections. Includes coverage of the latest vaccine products, recommendations, and effectiveness. Reviews emerging healthcare-associated infections, their management, control, and prevention. Contains a new chapter on Chorioamnionitis and Neonatal Consequences.

Book Description :

Drs. Cohen, Powderly and Opal, three of the most-respected names in infectious disease medicine, lead a diverse team of international contributors to bring you the latest knowledge and best practices. Extensively updated, the fourth edition includes brand-new information on advances in diagnosis of infection; Hepatitis C; managing resistant bacterial infections; and many other timely topics. An abundance of photographs and illustrations; a practical, clinically-focused style; highly-templated organization; and robust interactive content combine to make this clinician-friendly resource the fastest and best place to find all of the authoritative, current information you need. Hundreds of full-color photographs and figures provide unparalleled visual guidance. Consistent chapter organization and colorful layouts make for quick searches. Clinically-focused guidance from "Practice Points" demonstrates how to diagnose and treat complicated problems encountered in practice. The "Syndromes by Body System", "HIV and AIDS", and "International Medicine" sections are designed to reflect how practicing specialists think when faced with a patient. Sweeping updates include new or revised chapters on: Hepatitis C and antivirals Fungal infection and newer antifungals Microbiome and infectious diseases as well as advances in diagnosis of infection; Clostridium difficile epidemiology; infection control in the ICU setting; Chlamydia trachomatis infection; acquired syndromes associated with autoantibodies to cytokines;; management of multidrug resistant pathogens; probiotics, polymyxins, and the pathway to developing new antibiotics HIV including HIV and aging, antiretroviral therapy in developing countries, and cure for HIV

Book Description :

Each year, Advances in Pediatrics focuses on providing current clinical information on important topics in pediatrics. Dr. Carol Berkowitz and her editorial board, comprised of top experts in the field, have assembled authors to provide updates on the following topics: Evaluation and Management of Febrile Infants; Pediatric Emergency Medicine and Ultrasonography; The Patient-Centered Pediatric Emergency Department; Health Considerations of Refuge and Immigrant Children; Management of scoliosis; Health and Wellness for LGBTQ Youth; Sexually exploited children: recognizing and addressing; Movement disorders in children; Childhood trauma management in primary care; Feeding issues in young children; Physician Well-being and Burnout; New Molecular Methods for Diagnosing Infectious Diseases; Parental refusal: treatments, procedures and vaccines; Pediatric oncology in the ICU setting; Diaphragmatic hernia: Management and Outcomes; and Global Health and Pediatric Education: Opportunities and Challenges. Readers will come away with the clinical information that supplements their professional knowledge so they can make informed clinical decisions that improve patient outcomes.

Book Description :

This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Book Description :

This book provides a comprehensive, state-of-the-art review of the concepts vital to a modern treatment of common and opportunistic infections in the immunocompromised host. Chapters are written by experts in the field, and include their views on gaps in the field and future directions of research. This book begins with an overview of the normally functioning immune system followed by a detailed discussion of the major primary immunodeficiencies. Specific chapters are dedicated to providing practical knowledge in the prevention and treatment of infections in specific immunocompromised patients, including those with cancer, transplant recipients, HIV infection, and autoimmune disorders. Emphasis is placed on diagnostic evaluation, antimicrobial selection that includes consideration of the threat of antimicrobial-resistant pathogens, and immunotherapy tailored to specific patients. Finally, dedicated chapters on stem cell transplantation for patients with primary immunodeficiencies, adoptive cellular immunotherapy, and gene therapy will provide readers with insight into these rapidly evolving and cutting edge therapies.Management of Infections in the Immunocompromised Host is a valuable resource for infectious diseases specialists, immunologists, oncologists, hematologists, general physicians, students, researchers, and all other working with immunocompromised patients.

Book Description :

Written and edited by global leaders in the field, Pediatric Liver Transplantation: A Clinical Guide covers all aspects of treatment and management regarding this multifaceted procedure and unique patient population. This practical reference offers detailed, focused guidance in a highly templated, easy-to-consult format, covering everything from pre-transplantation preparation to surgical techniques to post-operative complications. Provides an in-depth understanding of all aspects of pediatric liver transplantation, ideal for pediatric hepatologists, pediatric transplant surgeons, and others on the pediatric transplant team. Covers all surgical techniques in detail, including split graft, living related, auxiliary, and domino. Discusses pediatric liver transplantation consideration for an increasing number of additional metabolic, hematologic and renal conditions; breakthroughs in grafting and stem cell therapy; and techniques and present role of hepatocyte transplantation. Uses a quick-reference templated format; each chapter includes an overview, pathophysiology, conventional management, controversies, and bulleted summary of key take-aways. Includes state-of-the-art mini-reviews based on updated references and author experience throughout the text. Features a full-color design with numerous algorithms, figures, and radiological and histopathological photos.