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Parkinson s Disease Therapeutics

Parkinson   s Disease Therapeutics Book
Author : Magisetty Obulesu
Publisher : Academic Press
Release : 2020-01-30
ISBN : 0128198834
Language : En, Es, Fr & De

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Book Description :

Parkinson’s Disease Therapeutics: Emphasis on Nanotechnological Advances presents the latest information on the second most common neurodegenerative disorder in the elderly. Despite remarkable progress in various PD therapeutics, such as microRNAs and brain drug delivery systems, a few limitations impede their success. This book sheds light on the pros and cons of recently developed novel therapeutics. Very few books have highlighted the protective efficacy of natural products, antioxidants, and biomaterial design for other diseases. Emphasizes novel therapeutics for Parkinson’s disease, including nanotechnology, natural products and antioxidants Discusses the pros and cons of recently developed therapy options for Parkinson's Focuses on the efficacy of nanotechnology in overcoming the blood-brain barrier and biomaterial design

Therapy of Parkinson s Disease

Therapy of Parkinson s Disease Book
Author : William C. Koller,George W. Paulson
Publisher : CRC PressI Llc
Release : 1995
ISBN :
Language : En, Es, Fr & De

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Book Description :

This work offers a comprehensive and fully updated overview of supportive patient management strategies, highlighting therapeutic approaches other that dopaminergic agents and conventional antiparkinsonian drugs. This second edition: reviews the neuroprotective effects of selegiline on Parkinson's disease; investigates ways of enhancing the effectiveness of levodopa-based therapy; presents methods of speech therapy with well-documented short- and long-term efficacy; and more.

Parkinson s Disease and Movement Disorders

Parkinson s Disease and Movement Disorders Book
Author : Joseph Jankovic,Eduardo Tolosa
Publisher : Lippincott Williams & Wilkins
Release : 2007
ISBN : 9780781778817
Language : En, Es, Fr & De

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Book Description :

Written by an international group of renowned experts, the Fifth Edition of this premier reference provides comprehensive, current information on the genetics, pathophysiology, diagnosis, medical and surgical treatment, and behavioral and psychologic concomitants of all common and uncommon movement disorders. Coverage includes Parkinson's disease, other neurodegenerative diseases, tremors, dystonia, Tourette's syndrome, Huntington's disease, and ataxias. This edition features extensive updates on genetics, imaging, and therapeutics of Parkinson's disease, other parkinsonian disorders, and all hyperkinetic movement disorders. A bound-in CD-ROM, Video Atlas of Movement Disorders, demonstrates the movement and posture abnormalities and other disturbances associated with Parkinson's disease and other neurologic disorders.

Therapeutics of Parkinson s Disease and Other Movement Disorders

Therapeutics of Parkinson s Disease and Other Movement Disorders Book
Author : Mark Hallett,Werner Poewe
Publisher : John Wiley & Sons
Release : 2008-10-13
ISBN : 047071400X
Language : En, Es, Fr & De

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Book Description :

Provides a comprehensive update on therapies for Parkinson’s disease and other movement disorders Describes the basic mechanisms of neurodegeneration, pharmacologic interventions for motor and non-motor symptoms, and surgical management Features summary tables and algorithms that serve as a quick reference guide for practical treatment decisions The expert guidance of recognised authorities will enable readers of this book to plan their patients’ care with greater confidence

Parkinson s Disease Current and Future Therapeutics and Clinical Trials

Parkinson s Disease  Current and Future Therapeutics and Clinical Trials Book
Author : Nestor Galvez-Jimenez,Hubert H. Fernandez,Alberto J. Espay,Susan H. Fox
Publisher : Cambridge University Press
Release : 2016-03-31
ISBN : 1107053862
Language : En, Es, Fr & De

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Book Description :

This book emphasizes treatment options for Parkinson's disease, providing the necessary clinical and scientific basis for the foundations of solid therapeutics.

Novel Therapeutic Approaches to the Treatment of Parkinson s Disease

Novel Therapeutic Approaches to the Treatment of Parkinson   s Disease Book
Author : Corey R. Hopkins
Publisher : Springer
Release : 2016-06-23
ISBN : 3319399268
Language : En, Es, Fr & De

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Book Description :

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Basic Clinical and Therapeutic Aspects of Alzheimer s and Parkinson s Diseases

Basic  Clinical  and Therapeutic Aspects of Alzheimer   s and Parkinson   s Diseases Book
Author : Toshiharu Nagatsu,Abraham Fisher,Mitsuo Yoshida
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1468458442
Language : En, Es, Fr & De

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Book Description :

This two-volume work contains the full text of the oral and poster presentations and the general discussion at the round table discussion of the Second International Conference on Alzheimer's and Parkinson's Diseases: Basic and Therapeutic Strategies, held at the Kyoto Park Hotel in Kyoto, Japan, on November 6-10, 1989. The First Conference was held at the Aviya Sonesta Hotel in Eilat, Israel, on March 24-27, 1985. The record of this First Conference was published by Plenum Press in 1986 as Volume 29 in Advances in Behavioral Biology, under the title "Alzheimer's and Parkinson's Diseases: Strategies for Research and Development." We are happy that the comprehensive texts of the oral and poster presentations of the Second Conference could again be published within the framework of this series. Since the First Conference in 1985, rapid progress has been made in both basic and 'therapeutic aspects of these diseases. About 700 scientists from allover the world participated in the Second Conference, and 300 papers were presented in oral and poster sessions. Many people and organizations have helped to organize this multi disciplinary international conference and hence have contributed to the scientific quality of these two volumes. We thank the members of the organizing committee, the organizations that provided financial support, and the contributing scientists for their enthusiastic participation. These two volumes follow the same publishing philosophy as the volume derived from the First Conference. They span a broad spectrum of topics and bridge preclinical and clinical concepts related to these diseases.

Cell Based Therapies for Parkinson s Disease Preclinical and Clinical Perspectives

Cell Based Therapies for Parkinson s Disease  Preclinical and Clinical Perspectives Book
Author : Andrea R. Di
Publisher :
Release : 2016
ISBN :
Language : En, Es, Fr & De

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Book Description :

Parkinson's Disease (PD) is a highly prevalent neurodegenerative disease that affects millions of people globally and remains without definitive treatment. There have been many recent advances in cell-based therapy to replace lost neural circuitry and provide chronic biological sources of therapeutic agents to disease-affected brain regions. Early neural transplantation studies highlighted the challenges of immune rejection, graft integration, and the need for renewable, autologous graft sources. Neurotrophic factors (NTFs) offer a potential class of cytoprotective agents that may complement dopamine (DA) replacement and cell-based therapies in PD. In fact, chronic NTF delivery may be an integral goal of cell transplantation in PD, with ideal grafts consisting of autologous drug (e.g., DA, NTF)-producing cells capable of integration and function in the host brain. This chapter outlines the past and recent preclinical and clinical advances in cell-based and NTF therapies as promising and integrated approaches for the treatment of PD.

Restorative Therapies in Parkinson s Disease

Restorative Therapies in Parkinson s Disease Book
Author : Patrik Brundin,C. Warren Olanow
Publisher : Springer Science & Business Media
Release : 2006-08-31
ISBN : 0387328238
Language : En, Es, Fr & De

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Book Description :

In this exciting and timely book new approaches to repairing the parkinsonian brain are described by leading experts. Never in history has there been greater hope that novel experimental therapies can support significant restoration of brain function. This book gives an overview of the current state-of-the-art research for brain repair, what the challenges are and an indication of what research can provide for the next generation of people with Parkinson’s disease. The comprehensive chapters are geared to an audience of neuroscientists, neurologists, neurosurgeons and anyone interested in how findings in the research laboratory can effectively be transferred to the clinic.

Therapy of Parkinson s Disease Third Edition

Therapy of Parkinson s Disease  Third Edition Book
Author : Rajesh Pahwa,Kelly E. Lyons,William Koller
Publisher : Marcel Dekker
Release : 2004-04-19
ISBN : 9780824754556
Language : En, Es, Fr & De

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Book Description :

A comprehensive review of current tactics in the therapeutic management of Parkinson's disease, this volume offers summaries of salient research findings as well as contemporary attitudes and practical advice from field specialists. The well-timed Third Edition is expanded and topically reorganized to register trends and progress in anti-parkinsonian medications, ablative surgical options, deep brain stimulation, nonmotor symptom treatments, nonmedical strategies, and investigational therapies.

Parkinson s Disease

Parkinson   s Disease Book
Author : F. Messiha,Alexander D. Kenny
Publisher : Springer
Release : 1977-10
ISBN :
Language : En, Es, Fr & De

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Book Description :

These Proceedings are the outcome of the First Tarbox Parkinson's Disease Symposium held October 14-16, 1976, at the South Park Inn in Lubbock, Texas. The Symposium was sponsored by the Department of Pharmacology and Therapeutics and the Tarbox Parkinson's Disease In stitute of the Texas Tech University School of Medicine at Lubbock. The Tarbox Parkinson's Disease Institute was established in 1973 with funds appropriated by the State of Texas and is dedicated to re search, patient care, and educational activities related to Parkinson's disease. The Institute is named after Mr. Elmer L. Tarbox, who recently served the Lubbock area as a Representative to the Texas Legislature, and is himself a parkinsonian patient. Mr. and Mrs. Tarbox attended the Symposium as honored guests. The First Tarbox Parkinson's Disease Symposium was devoted to both basic and clinical aspects of Parkinson's disease, with an emphasis on discussion of drug therapy. This discussion focused not only on readily available drugs such as levodopa, but also on new investigational drugs such as bromocriptine. Thanks are especially due to Thelma Saunders and the office staff of the Department of Pharmacology and Therapeutics, Texas Tech Univer sity School of Medicine, for their excellent service in producing camera-ready copy for the Publisher. Thanks are also due to Fathy S. Messiha, Program Chairman, to the other committee members, and to the staff of the Office of Continuing Education and Faculty Development. The Symposium could not have succeeded without their help.

Parkinson s Disease

Parkinson s Disease Book
Author : Dr. Stewart A. Factor, DO,Dr. William Weiner, MD
Publisher : Demos Medical Publishing
Release : 2007-12-15
ISBN : 9781934559871
Language : En, Es, Fr & De

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Book Description :

Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson's Disease: Diagnosis and Clinical Management comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson's disease. The book includes 23 completely new chapters, and has updated information on: Genetics Pathology Biomarkers Pathogenesis Impulse control disorders in Parkinson's disease Updated outcome measures Complementary and alternative medicine for the treatment of Parkinson's disease Together the chapters form a comprehensive review of the many issues facing PD physicians today. Lucid and easily readable from beginning to end, each chapter may also stand on its own as a scholarly review of the individual subject. Each one is concisely written and heavily referenced for this purpose. The second edition of Parkinson's Disease: Diagnosis and Clinical Management provides a state-of-the-art review of where we've been, where we are now, and where we are going in treating this disease.

Parkinsons s Disease

Parkinsons s Disease Book
Author : Peter Lewitt,Wolfgang H Oertel
Publisher : CRC Press
Release : 1999-05-30
ISBN : 9781853173790
Language : En, Es, Fr & De

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Book Description :

With the general population becoming increasingly aware of new developments for the diagnosis and treatment of certain neurological disorders throught increased media coverage in the popular press and on television and with celebrities being affected, the clinician must be aware of all the latest developments inthe diagnosis and treatment of disease. Parkinson's disease is no different. Peter LeWitt and Wolfgang Oertel have assembled an international team of contributors to write on their particular areas of expertise to produce a work which will help the practising clinician. This book captures all the latest information: the most important developments in the research of Parkinson's disease in recent years and the many different approaches to the treatment of the disease. These are exciting times for the study of Parkinson's disease, and this book condenses the wealth of available information into a practical text.

Principles of Treatment in Parkinson s Disease

Principles of Treatment in Parkinson s Disease Book
Author : Anthony Henry Vernon Schapira,Charles Warren Olanow
Publisher : Elsevier Health Sciences
Release : 2005
ISBN : 0750654287
Language : En, Es, Fr & De

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Book Description :

This succinct volume offers an up-to-date review and comparison of the treatment options available for Parkinson's disease, and provides evidence-based recommendations on appropriate treatments for specific cases. Offers expert guidance on the best treatment options from authorities in the field. Delivers expert guidance on drug therapies, physical therapies, and surgical interventions. Discusses conditions such as depression · hallucinations · cognition · and sleep disorders. Explores neuroprotection in Parkinson's disease. Provides insights into future therapies.

Non Invasive Neuromodulation Therapies for Parkinson s Disease

Non Invasive Neuromodulation Therapies for Parkinson s Disease Book
Author : Milton C. Biagioni
Publisher :
Release : 2018
ISBN :
Language : En, Es, Fr & De

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Book Description :

Noninvasive brain stimulation (NIBS) technologies have been applied to study brain physiology and, more recently, have been recognized for their therapeutic potential as an adjunctive treatment for various neurologic and psychiatric disorders. Transcranial magnetic stimulation (TMS) and transcranial electric stimulation (tES) are two of the most studied NIBS modalities in Parkinson's disease. They are non-systemic and relatively safe. Most therapeutic trials have been conducted to ameliorate motor symptoms of Parkinson's disease (PD) with overall positive results using various stimulation modalities and methods. Notwithstanding significant results, evidence has not yet been compelling mainly due to small-size studies, lack of standardization of methodologies and other study design limitations. NIBS hold promise for treatment of PD symptoms and PD related complications. Large, well designed clinical trials are needed to corroborate these positive findings and inform its durability and the overall clinical relevance for the treatment of PD.

Clinical Pharmacy and Therapeutics E Book

Clinical Pharmacy and Therapeutics E Book Book
Author : Roger Walker
Publisher : Elsevier Health Sciences
Release : 2011-10-24
ISBN : 0702048488
Language : En, Es, Fr & De

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Book Description :

Now in its fifth edition, this best-selling, multidisciplinary textbook continues to draw on the skills of pharmacists and clinicians to present optimal drug regimens. The authors integrate an understanding of the disease processes with an appreciation of pathophysiological processes, clinical pharmacy and the evidence base. New to this edition: Stronger emphasis on understanding both the prescribing process and the clinical pharmacy process. All chapters completely revised and updated. Thirty-eight leading new authors. Features: Key points boxes at the beginning of every chapter Case study tests at the end of every chapter Chapters co-authored by pharmacists and clinicians Organised by body system Consistent, clearly signposted chapter layout ‘...a unique and valuable support for all those involved or interested in drug therapy. This is a textbook that no university or pharmacy department, particularly those with employees studying at any level, and no pharmacist trying to develop their knowledge base should be without." Dr Chris Green and John Sexton, The Pharmaceutical Journal Now in its fifth edition, this best-selling, multidisciplinary textbook continues to draw on the skills of pharmacists and clinicians to present optimal drug regimens. The authors integrate an understanding of the disease processes with an appreciation of pathophysiological processes, clinical pharmacy and the evidence base. New to this edition: Stronger emphasis on understanding both the prescribing process and the clinical pharmacy process. All chapters completely revised and updated. Thirty-eight leading new authors. Features: Key points boxes at the beginning of every chapter Case study tests at the end of every chapter Chapters co-authored by pharmacists and clinicians Organised by body system Consistent, clearly signposted chapter layout ‘...a unique and valuable support for all those involved or interested in drug therapy. This is a textbook that no university or pharmacy department, particularly those with employees studying at any level, and no pharmacist trying to develop their knowledge base should be without." Dr Chris Green and John Sexton, The Pharmaceutical Journal Stronger emphasis on understanding both the prescribing process and the clinical pharmacy process. All chapters completely revised and updated. Thirty-eight leading new authors.

Parkinson s Disease

Parkinson s Disease Book
Author : Ronald F. Pfeiffer,Zbigniew K. Wszolek,Manuchair Ebadi
Publisher : CRC Press
Release : 2004-12-28
ISBN : 0203508599
Language : En, Es, Fr & De

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Book Description :

Recent research is leading to an ever-increasing range of investigative approaches whose aim is to achieve effective neuroprotective or neurorestorative treatment for individuals affected by Parkinson’s disease. New directions under investigation reach beyond traditional pharmacological approaches to venture into innovative surgical methods, gene therapy, stem cell therapy, and neurotransplantation. In this comprehensive volume, leading medical authorities provide state-of-the-art information on all aspects of Parkinson’s disease. They cover the historical background, neuropathological and neurophysiological characteristics, epidemiological aspects, clinical features, current treatment approaches, and potential therapeutic methods. Novel models are included to simplify more complex concepts.