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Oxidative Stress And Dietary Antioxidants In Neurological Diseases

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Oxidative Stress and Dietary Antioxidants in Neurological Diseases

Oxidative Stress and Dietary Antioxidants in Neurological Diseases Book
Author : Colin R. Martin,Victor R Preedy
Publisher : Academic Press
Release : 2020-06-12
ISBN : 0128177810
Language : En, Es, Fr & De

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Book Description :

Oxidative Stress and Dietary Antioxidants in Neurological Diseases provides an overview of oxidative stress in neurological diseases and associated conditions, including behavioral aspects and the potentially therapeutic usage of natural antioxidants in the diet. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. The book examines basic processes of oxidative stress—from molecular biology to whole organs—relative to cellular defense systems, and across a range of neurological diseases. Sections discuss antioxidants in foods, including plants and components of the diet, examining the underlying mechanisms associated with therapeutic potential and clinical applications. Although some of this material is exploratory or preclinical, it can provide the framework for further in-depth analysis or studies via well-designed clinical trials or the analysis of pathways, mechanisms, and components in order to devise new therapeutic strategies. Very often oxidative stress is a feature of neurological disease and associated conditions which either centers on or around molecular and cellular processes. Oxidative stress can also arise due to nutritional imbalance during a spectrum of timeframes before the onset of disease or during its development. Offers an overview of oxidative stress from molecular biology to whole organs Discusses the potentially therapeutic usage of natural antioxidants in the patient diet Provides the framework for further in-depth analysis or studies of potential treatments

Micronutrients in Health and Disease

Micronutrients in Health and Disease Book
Author : Kedar N. Prasad
Publisher : CRC Press
Release : 2016-04-19
ISBN : 9781439821077
Language : En, Es, Fr & De

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Book Description :

Increased oxidative stress due to the production of excessive amounts of free radicals along with the effects of chronic inflammation play a major role in the initiation and progression of a host of disease states, ranging from cancer to posttraumatic stress disorder. In varying doses, micronutrients, including antioxidants, B vitamins, and mineral

Assessments Treatments and Modeling in Aging and Neurological Disease

Assessments  Treatments and Modeling in Aging and Neurological Disease Book
Author : Colin R. Martin,Victor R. Preedy,Rajkumar Rajendram
Publisher : Academic Press
Release : 2021-06-28
ISBN : 0128180013
Language : En, Es, Fr & De

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Book Description :

Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging is a comprehensive reference on the diagnosis and management of neurological aging and associated disorders. The book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. It also examines pharmacological and non-pharmacological interventions of age-related conditions that affect the brain, including Alzheimer’s, stroke and multiple sclerosis. Provides the most comprehensive coverage of the broad range of topics related to the neuroscience of aging Features sections on diagnosis and biomarkers of neurological aging, Alzheimer’s and stroke Contains an abstract, key facts, a mini dictionary of terms, and summary points in each chapter Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations Includes more than 500 illustrations and tables

Antioxidants in Human Health and Disease

Antioxidants in Human Health and Disease Book
Author : Nina Pegg
Publisher : Unknown
Release : 2020-09-15
ISBN : 9781632418319
Language : En, Es, Fr & De

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Book Description :

Living organisms require oxygen for survival, but it is also a highly reactive molecule that can damage organisms by producing reactive oxygen species. Oxidation is the chemical reaction that produces free radicals and thereby leads to chain reactions with the potential to damage the cells of organisms. Antioxidants inhibit oxidation. Ascorbic acid or thiols are antioxidants that can terminate these chain reactions. Organisms have a complex system of antioxidant metabolites and enzymes that work in tandem to prevent oxidative damage to DNA, proteins and lipids. However, reactive oxygen species have useful cellular functions as well, such as redox signaling. Antioxidant systems therefore do not remove oxidants completely but keep them at an optimum level. The role of oxidative stress in degenerative diseases, such as diabetes, kidney disease, neurological disorders, obesity, cancer and aging is understood. This makes antioxidant dietary supplements a potential strategy to overcome these conditions. This book provides comprehensive insights into antioxidants and their role in human health and disease. It will also provide interesting topics for research, which interested readers can take up. With state-of-the-art inputs by acclaimed experts of this field, this book targets students and professionals.

Natural Antioxidants in Human Health and Disease

Natural Antioxidants in Human Health and Disease Book
Author : Balz Frei
Publisher : Academic Press
Release : 2012-12-02
ISBN : 0080571689
Language : En, Es, Fr & De

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Book Description :

This book serves as a comprehensive overview of the current scientific knowledge on the health effects of dietary and supplemental antioxidants (such as vitamins C and E). Chapters integrate information from basic research and animal studies, epidemiologic studies, and clinical intervention trials. The popular media has taken great interest in antioxidants, with numerous articles emphasizing their role in preventing disease and the possible slowing of the aging process. These antioxidant vitamins may be important in preventing not only acute deficiency symptoms, but also chronic disorders such as heart disease and certain types of cancer. This book, therefore, is not only for scientists and doctors, but also for health writers, journalists, and informed lay people. The text focuses on several human conditions for which there is now good scientific evidence that oxidation is an important etiological component. Specifically, antioxidants may prevent or slow down the progression of: Cancer, Cardiovascular disease, Immune system disorders, Cataracts, Neurological disorders, Degeneration due to the aging process.

Micronutrients in Health and Disease Second Edition

Micronutrients in Health and Disease  Second Edition Book
Author : Kedar N. Prasad
Publisher : CRC Press
Release : 2019-04-15
ISBN : 0429513186
Language : En, Es, Fr & De

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Book Description :

Increased oxidative stress due to the production of excessive amounts of free radicals along with the effects of chronic inflammation plays a major role in the initiation and progression of most chronic diseases. In addition, increased release of glutamate plays a central role in the pathogenesis of various disorders. This second edition of Micronutrients in Health and Disease proposes a novel concept that in order to simultaneously and optimally reduce oxidative stress, chronic inflammation, and glutamate, it is essential to increase levels of antioxidant enzymes as well as levels of dietary and endogenous antioxidant compounds at the same time. This is accomplished by activating the Nrf2 pathways and by increasing the levels of antioxidant compounds and B-vitamins through supplementation. This book proposes a mixture of micronutrients that achieves this above goal. The mixture of micronutrients together with modification in diet and lifestyle may reduce the risk of chronic diseases and in combination with standard care, may improve the management of these diseases. KEY FEATURES • Provides evidence in support of the idea that increased oxidative stress, chronic inflammation, and glutamate are involved in the pathogenesis of chronic diseases. • Contains three new chapters on Huntington’s disease, Autism spectra, and Prion disease. • Discusses the role of microRNAs in the pathogenesis of chronic diseases. • Presents information on regulation of the expression of microRNAs by reactive oxygen species and antioxidants. Micronutrients in Health and Disease, Second Edition serves as a valuable resource for those seeking to promote healthy aging and prevent and improved management of chronic diseases.

Phytoantioxidants and Nanotherapeutics

Phytoantioxidants and Nanotherapeutics Book
Author : Mithun Rudrapal
Publisher : Wiley
Release : 2022-07-06
ISBN : 9781119811770
Language : En, Es, Fr & De

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Book Description :

The book comprehensively reviews the medicinal importance of phytomedicine-derived antioxidants with their development into nano-sized drug delivery systems for a wide range of diseases such as cancer, inflammation, diabetes, viral and parasitic infections, nervous system disorders, cardiovascular disorders, and neurological diseases. The chapters cover phytomedicine-derived bioactive compounds as antioxidants and their role in oxidative stress induced human diseases. In addition, they discuss herbs, plant extracts, and other dietary elements as sources of natural antioxidants and their potential medicinal benefits. Biochemical and therapeutic targets of nanodrugs are featured along with nanostructure toxicity . Finally, this book highlights the challenges and regulatory issues involved with nanophytotherapeutics.

Diet and Exercise in Cognitive Function and Neurological Diseases

Diet and Exercise in Cognitive Function and Neurological Diseases Book
Author : Akhlaq A. Farooqui,Tahira Farooqui
Publisher : John Wiley & Sons
Release : 2015-02-05
ISBN : 1118840577
Language : En, Es, Fr & De

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Book Description :

Diet and exercise have long been recognized as important components of a healthy lifestyle, as they have a great impact on improving cardiovascular and cerebrovascular functions, lowering the risk of metabolic disorders, and contributing to healthy aging. As a greater proportion of the world’s population is living longer, there has been increased interest in understanding the role of nutrition and exercise in long-term neurological health and cognitive function. Diet and Exercise in Cognitive Function and Neurological Diseases discusses the role and impact that nutrition and activity have on cognitive function and neurological health. The book is divided into two sections. The first section focuses on diet and its impact on neurobiological processes. Chapters focus on the impacts of specific diets, such as the Mediterranean, ketogenic and vegan diets, as well as the role of specific nutrients, fats, fatty acids, and calorie restriction on neurological health and cognitive function. The second section of the book focuses on exercise, and its role in maintaining cognitive function, reducing neuroinflammatory responses, regulating adult neurogenesis, and healthy brain aging. Other chapters look at the impact of exercise in the management of specific neurological disorders such Multiple Sclerosis and Parkinson’s Disease. Diet and Exercise in Cognitive Function and Neurological Diseases is a timely reference on the neurobiological interplay between diet and exercise on long-term brain health and cognitive function.

Fight Parkinson s and Huntington s with Vitamins and Antioxidants

Fight Parkinson s and Huntington s with Vitamins and Antioxidants Book
Author : Kedar N. Prasad
Publisher : Simon and Schuster
Release : 2016-03-17
ISBN : 1620554348
Language : En, Es, Fr & De

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Book Description :

The most up-to-date resource on the powerful benefits of nutritional supplements for the treatment of Parkinson’s and Huntington’s disease • Provides an easy-to-follow program of supplements to optimize the benefits of treatment, slow the progression of symptoms, and help delay onset in those predisposed to these diseases • Shows how specific combinations of antioxidants counteract the oxidative stress and chronic inflammation at the root of these diseases • Based on more than 35 years of scientific and medical research In this practical scientific guide, micronutrient researcher Kedar N. Prasad, Ph.D., reveals the latest revolutionary discoveries on the use of antioxidants to treat Parkinson’s and Huntington’s disease. He details how the proper combinations of vitamin and antioxidant supplements, along with polyphenic compounds such as curcumin and resveratrol, can greatly increase the effectiveness of standard medical treatments for these diseases, slowing the progression of symptoms as well as delaying onset despite family history. Prasad shows how oxidative stress and chronic inflammation play a significant role in the initiation and progression of neurodegenerative diseases like Parkinson’s and Huntington’s disease. He provides an easy-to-follow daily supplement regimen to target free-radical damage and inflammation and slow the progression of these diseases. Reviewing the scientific research on micronutrients and neurodegenerative disease, he debunks the flawed conclusions of the neurological community that vitamins and antioxidants are ineffective, revealing how their studies focused on specific micronutrients used alone rather than synergistic combinations. Offering a safe self-help complement to standard medications, this guide provides a truly holistic approach to the prevention and treatment of both Parkinson’s and Huntington’s disease.

Non Timber Forest Products

Non Timber Forest Products Book
Author : Azamal Husen,Rakesh Kumar Bachheti,Archana Bachheti
Publisher : Springer Nature
Release : 2021-07-30
ISBN : 3030730778
Language : En, Es, Fr & De

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Book Description :

Forests cover thirty-one percent of the world’s land surface, provide habitats for animals, livelihoods for humans, and generate household income in rural areas of developing countries. They also supply other essential amenities, for instance, they filter water, control water runoff, protect soil erosion, regulate climate, store nutrients, and facilitate countless non-timber forest products (NTFPs). The main NTFPs comprise herbs, grasses, climbers, shrubs, and trees used for food, fodder, fuel, beverages, medicine, animals, birds and fish for food, fur, and feathers, as well as their products, like honey, lac, silk, and paper. At present, these products play an important role in the daily life and well-being of millions of people worldwide. Hence the forest and its products are very valuable and often NTFPs are considered as the ‘potential pillars of sustainable forestry’. NTFPs items like food, herbal drugs, forage, fuel-wood, fountain, fibre, bamboo, rattans, leaves, barks, resins, and gums have been continuously used and exploited by humans. Wild edible foods are rich in terms of vitamins, protein, fat, sugars, and minerals. Additionally, some NTFPs are used as important raw materials for pharmaceutical industries. Numerous industry-based NTFPs are now being exported in considerable quantities by developing countries. Accordingly, this sector facilitates employment opportunities in remote rural areas. So, these developments also highlight the role of NTFPs in poverty alleviation in different regions of the world. This book provides a wide spectrum of information on NTFPs, including important references. We hope that the compendium of chapters in this book will be very useful as a reference book for graduate and postgraduate students and researchers in various disciplines of forestry, botany, medical botany, economic botany, ecology, agroforestry, and biology. Additionally, this book should be useful for scientists, experts, and consultants associated with the forestry sector.

Antioxidants in Health and Disease

Antioxidants in Health and Disease Book
Author : Antonis Zampelas,Renata Micha
Publisher : CRC Press
Release : 2015-06-09
ISBN : 1466580119
Language : En, Es, Fr & De

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Book Description :

Antioxidant use in health promotion and disease prevention either through dietary intake or supplementation is controversial. This book reviews the latest evidence-based research in the area, principally through prospective cohort studies and randomized controlled trials. It assesses major dietary antioxidants and discusses their use in diseases such as cancer, diabetes, stroke, coronary heart disease, HIV/AIDS, and neurodegenerative and immune diseases. The use of antioxidants in health is also discussed along with common adverse effects associated with antioxidant use.

Nutritional Antioxidant Therapies Treatments and Perspectives

Nutritional Antioxidant Therapies  Treatments and Perspectives Book
Author : Kaïs Hussain Al-Gubory,Ismail Laher
Publisher : Springer
Release : 2018-03-10
ISBN : 3319676253
Language : En, Es, Fr & De

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Book Description :

This book offers a collection of expert reviews on the use of plant-based antioxidant therapies in disease prevention and treatment. Topics discussed include the uses of plant and nutritional antioxidants in the contexts of reproductive health and prenatal development, healthcare and aging, noncommunicable chronic diseases, and environmental pollution. The text is complemented by a wealth of color figures and summary tables.

Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease

Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease Book
Author : Ronald Ross Watson,Victor R. Preedy
Publisher : Academic Press
Release : 2014-09-11
ISBN : 0124115292
Language : En, Es, Fr & De

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Book Description :

Nutritional supplement research concerning brain health and neurological disease is becoming an important focus. While nutritional supplements are very popular for general health and well being, the effectiveness of common supplements and their impact on general brain health and for the treatment or prevention of neurological disease is not clearly understood. This comprehensive introduction to bioactive nutraceuticals for brain and neurological provides a foundation review for research neuroscientists, clinical neurologists, pharmacology researchers and nutrition scientists on what we know now about these supplements and the brain and where focused research is still necessary. Foundational review content covering nutrition and brain and neurological health Reviews known nutritional supplements and impact on brain and neurological health Comprehensive coverage ideal for research scientists and clinical practitioners

Phytochemicals

Phytochemicals Book
Author : Venketeshwer Rao,Leticia Rao
Publisher : BoD – Books on Demand
Release : 2015-09-30
ISBN : 9535121707
Language : En, Es, Fr & De

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Book Description :

Global dietary recommendations emphasize the consumption of plant-based foods for the prevention and management of chronic diseases. Plants contain many biologically active compounds referred to as phytochemicals or functional ingredients. These compounds play an important role in human health. Prior to establishing the safety and health benefits of these compounds, they must first be isolated, purified, and their physico-chemical properties established. Once identified, their mechanisms of actions are studied. The chapters are arranged in the order from isolation, purification and identification to in vivo and clinical studies, there by covering not only the analytical procedures used but also their nutraceutical and therapeutic properties.

Treat Concussion TBI and PTSD with Vitamins and Antioxidants

Treat Concussion  TBI  and PTSD with Vitamins and Antioxidants Book
Author : Kedar N. Prasad
Publisher : Simon and Schuster
Release : 2015-12-17
ISBN : 1620554364
Language : En, Es, Fr & De

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Book Description :

The most up-to-date resource on nutritional supplements for the prevention and improved management of concussive injury, TBI, and PTSD • Provides an easy-to-follow program of supplements to optimize the benefits of treatment programs and offer a method of prevention beyond the use of helmets • Shows how standard treatments do not address the oxidative stress, chronic inflammation, and high glutamate levels that promote brain injury progression • Explains how single micronutrients do not provide the same preventive benefits as the synergistic combinations explored in the book The human brain is highly complex. When brain injury strikes, whether from a blow to the head or the shock of physical or emotional trauma, successful treatment requires a multilevel approach, taking into account the health of the brain prior to injury. Multilevel, complementary treatment approaches can also be applied to strengthen the uninjured brain and help prevent neurological injury for those at high risk of concussion, post-traumatic stress disorder, and traumatic brain injury. In this practical scientific guide, leading researcher in cancer, heart disease, and Alzheimer’s prevention Kedar N. Prasad, Ph.D., reveals the latest revolutionary discoveries on the use of antioxidants and micronutrients to manage and prevent concussive injury, TBI, and PTSD. He explains that increased oxidative stress, chronic inflammation, and glutamate release are common underlying factors in these conditions and should be addressed for improved management. He debunks the flawed conclusions of the neurological community that vitamins and antioxidants are ineffective for these conditions, revealing how their studies focused on specific micronutrients rather than synergistic combinations. The author details his easy-to-follow supplement program to treat and prevent these injuries, outlining the correct daily amounts and proper combinations of vitamins, antioxidants, micronutrients, and polyphenolic compounds such as curcumin and resveratrol. Offering the missing complement to standard medical care of brain injury as well as a form of prevention beyond the use of helmets, this guide provides a truly holistic approach to the prevention and management of concussive injury, TBI, and PTSD.

Flavonoids in Health and Disease Second Edition

Flavonoids in Health and Disease  Second Edition Book
Author : Catherine A. Rice-Evans,Lester Packer
Publisher : CRC Press
Release : 2003-05-20
ISBN : 9781439858110
Language : En, Es, Fr & De

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Book Description :

Revised and expanded, this blue-ribbon reference emphasizes the latest developments in the identification, utilization, and analysis of flavonoids for the prevention of disease and maintenance of good health. The book examines the processes involved in the absorption, metabolism, distribution, and excretion of these compounds and the impact of biotransformation on flavonoid function.The Second Edition contains new discussions on the potential of dietary flavonoids to attenuate neurological dysfunction and degeneration, developments in gene expression and genomics for identification of therapeutic targets and markers of disease, and the mechanisms regulating flavonoid bioavailability.

Biological Macromolecules

Biological Macromolecules Book
Author : Amit Kumar Nayak,Amal Kumar Dhara,Dilipkumar Pal
Publisher : Academic Press
Release : 2021-12-01
ISBN : 0323856381
Language : En, Es, Fr & De

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Book Description :

Biological Macromolecules: Bioactivity and Biomedical Applications presents a comprehensive study of biomacromolecules and their potential use in various biomedical applications. Consisting of four sections, the book begins with an overview of the key sources, properties and functions of biomacromolecules, covering the foundational knowledge required for study on the topic. It then progresses to a discussion of the various bioactive components of biomacromolecules. Individual chapters explore a range of potential bioactivities, considering the use of biomacromolecules as nutraceuticals, antioxidants, antimicrobials, anticancer agents, and antidiabetics, among others. The third section of the book focuses on specific applications of biomacromolecules, ranging from drug delivery and wound management to tissue engineering and enzyme immobilization. This focus on the various practical uses of biological macromolecules provide an interdisciplinary assessment of their function in practice. The final section explores the key challenges and future perspectives on biological macromolecules in biomedicine. Covers a variety of different biomacromolecules, including carbohydrates, lipids, proteins, and nucleic acids in plants, fungi, animals, and microbiological resources Discusses a range of applicable areas where biomacromolecules play a significant role, such as drug delivery, wound management, and regenerative medicine Includes a detailed overview of biomacromolecule bioactivity and properties Features chapters on research challenges, evolving applications, and future perspectives

Investigating Neurological Disease

Investigating Neurological Disease Book
Author : Albert Hofman,Richard Mayeux
Publisher : Cambridge University Press
Release : 2001-08-30
ISBN : 9780521000093
Language : En, Es, Fr & De

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Book Description :

This invaluable handbook for clinicians reviews the epidemiology, treatment and prognosis of all major diseases of the nervous system.

Diet Brain Connections

Diet     Brain Connections Book
Author : Mark P. Mattson
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461510678
Language : En, Es, Fr & De

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Book Description :

Diet-Brain Connections fills a void between the fields of nutrition, behavior and cellular and molecular neurosciences by providing an integrated collection of articles that critically dissect the link between what we eat and how the brain develops and functions in health and disease. Key topics covered in depth include: -caloric restriction benefit the brain and retard aging; -effects of dietary antioxidants on brain function and aging; -developmental and function consequences of different dietary fatty acids; -biochemical links between dietary folic acid and psychiatric and neurodegenerative disorders; -effects of nutritional deficit during early development and behavior disorders later in life; -neurochemical basis of the benefits of widely used dietary supplements including creatine and Gingko biloba; -contribution of dietary toxins such as metals and pesticides to neurological disorders.