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Overcoming Cancers Resistant To Her 2 Antibodies

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Current Applications for Overcoming Resistance to Targeted Therapies

Current Applications for Overcoming Resistance to Targeted Therapies Book
Author : Myron R. Szewczuk,Bessi Qorri,Manpreet Sambi
Publisher : Springer
Release : 2019-07-15
ISBN : 303021477X
Language : En, Es, Fr & De

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Book Description :

Targeted therapies were initially developed to exploit the upregulation and dependence on key oncogenic pathways critical to cancer progression. Additionally, they also presented as a method to overcome chemoresistance by supplementing conventional therapeutic regimens with targeted therapies. However, the development of resistance to these combinatorial approaches has led to the reassessment of currently available therapeutic options to overcome resistance to targeted therapy. This book aims to provide an update on the advancements in the therapeutic arms race between cancer, clinicians and scientists alike to overcome resistance to targeted therapies. Subject experts provide a comprehensive overview of the challenges and solutions to resistance to several conventional targeted therapies in addition to providing a discussion on broad topics including targeting components of the tumor microenvironment, emerging therapeutic options, and novel areas to be explored concerning nanotechnology and the epigenome.

Journal of the National Cancer Institute

Journal of the National Cancer Institute Book
Author : Anonim
Publisher : Unknown
Release : 1991-10
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Journal of the National Cancer Institute book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Resistance to Immunotherapeutic Antibodies in Cancer

Resistance to Immunotherapeutic Antibodies in Cancer Book
Author : Benjamin Bonavida
Publisher : Springer Science & Business Media
Release : 2013-08-04
ISBN : 1461476542
Language : En, Es, Fr & De

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Book Description :

​​​​The traditional approaches to treat various cancers include chemotherapy, radiation and/or hormonal therapy. While these therapies continue to be effective in large part, they are not selective and highly toxic. There have been encouraging results in alternative therapeutic approach called antibody-mediated anti-cancer therapy, which is less toxic, more selective, and can also reverse drug/radiation resistance. Monoclonal antibodies or mAbs can be used to destroy malignant tumor cells and prevent tumor growth by blocking specific cell receptors. mAbs can bind only to cancer cell-specific antigens and induce an immunological response against the target cancer cell. The book covers the common and unique features of mAbs agains various cancer, gives the latest developments on the molecular, biochemical and genetic mechanisms of resistance by various mAbs, as well as discuss novel mAbs to overcome resistance.

Index Medicus

Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Breast Cancer Management

Breast Cancer Management Book
Author : Lynda R. Wiseman
Publisher : Lippincott Williams & Wilkins
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Breast Cancer Management book written by Lynda R. Wiseman, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2006-08
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Cancer Immunology Immunotherapy

Cancer Immunology  Immunotherapy Book
Author : Anonim
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cancer Immunology Immunotherapy book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Recent Developments in Monoclonal Antibody Therapy for Breast Cancer

Recent Developments in Monoclonal Antibody Therapy for Breast Cancer Book
Author : Brittany Jiang
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Recent Developments in Monoclonal Antibody Therapy for Breast Cancer book written by Brittany Jiang, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Oncology

Oncology Book
Author : Anonim
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Anticancer Research

Anticancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Acta Obstetricia Et Gynecologica Scandinavica

Acta Obstetricia Et Gynecologica Scandinavica Book
Author : Anonim
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Acta Obstetricia Et Gynecologica Scandinavica book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The International Journal of Biological Markers

The International Journal of Biological Markers Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Surgical Foundations

Surgical Foundations Book
Author : Michael S. Sabel,Vernon K. Sondak,Jeffrey J. Sussman
Publisher : Mosby
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

A "mini-textbook" that delivers practical, need-to-know information in surgical oncology in an economical and user-friendly format. Coverage progresses from key basic science knowledge, principles of oncology care and research, to general diagnostic and operative procedures for a variety of cancers. Each chapter begins with key poings, presents crucial facts in boxes, and offers abundant illustrations, photographs, and tables to clarify complex concepts.

Tumor Progression and Therapeutic Resistance

Tumor Progression and Therapeutic Resistance Book
Author : Wafik S. El-Deiry
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This volume presents the entire breadth of translational cancer research and brings together members of academia and industry in the expectation of accelerating interactions and progress in the field. A variety of key topics are presented, beginning with discovery of molecular targets and pathways (oncogene, cell survival, tumor suppression, cell death), host-neoplasm interactions (cell adhesion, matrix proteases), early detection, monitoring progression, understanding tumor progression and metastasis, immune surveillance, in vivo molecular imaging, animal models, drug discovery including chemistry, high-throughput assays, mechanism determination, target validation, therapeutic window and some progress in clinical trials for more advanced agents and targets.

Cancer and its Nutritional Therapies

Cancer and its Nutritional Therapies Book
Author : Dr. Richard A. Passwater's
Publisher : Unknown
Release : 1978
ISBN : 9780879831707
Language : En, Es, Fr & De

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Book Description :

Download Cancer and its Nutritional Therapies book written by Dr. Richard A. Passwater's, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Drug Resistance in Oncology

Drug Resistance in Oncology Book
Author : Beverly A. Teicher
Publisher : Marcel Dekker Incorporated
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This volume focuses on the mechanisms that involve alterations in cellular biochemistry, properties related to the physiology of the solid tumour mass and changes in the host metabolic status induced by the presence of the tumour - applying this information to the resistance to cancer chemotherapy, radiation therapy and biomodulator therapies. angiogenesis and blood-flow, pH, oxygenation, molecular transport and tissue pressure, oncogenes and tumour-suppressor genes, extracellular matrix and phosphate metabolism; discusses clonal subpopulations, resistance in leukimia, the blood brain barrier, tumour/host interactions and the metastatic phenotype; examines glutathione, metallothionein, glutathione-S-transferases, oxazaphosphorane metabolism, cytochrome P-450, multi-drug resistance and nuclear matrix influence; and presents the effects of antioestrogens, chorionic gonadotropin, transforming and fibroblast growth factors, metastases and radiation resistance.

Science Culture

Science   Culture Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Reversal of Drug Resistance in Non Hodgkin s Lymphoma by Immunotherapy

Reversal of Drug Resistance in Non Hodgkin s Lymphoma by Immunotherapy Book
Author : Steve Anthony Alas
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Reversal of Drug Resistance in Non Hodgkin s Lymphoma by Immunotherapy book written by Steve Anthony Alas, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Journal of Immunology

The Journal of Immunology Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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