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Osteoimmunology

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Osteoimmunology

Osteoimmunology Book
Author : Yongwon Choi
Publisher : Springer Science & Business Media
Release : 2012-12-09
ISBN : 1461453666
Language : En, Es, Fr & De

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Book Description :

This is the second edition of this proceedings. Contributors include leading names in the field of research, addressing mutiple topics, which were covered at the last Osteoimmunology conference.

Osteoimmunology

Osteoimmunology Book
Author : Joseph Lorenzo,Mark Horowitz,Yongwon Choi,Hiroshi Takayanagi,Georg Schett
Publisher : Academic Press
Release : 2015-09-23
ISBN : 0128006277
Language : En, Es, Fr & De

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Book Description :

Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget’s disease, the genetics of bone disease, and bone cancer metastasis. Explains the intricate interaction between the immune system and bone Features detailed discussions of the key cellular and molecular mechanisms governing the homeostasis of the individual systems Facilitates greater understanding of osteoimmunologic networks, their environments, and how this understanding leads to better treatments for human diseases involving both systems

Osteoimmunology

Osteoimmunology Book
Author : Yongwon Choi
Publisher : Springer Science & Business Media
Release : 2007-10-05
ISBN : 038772009X
Language : En, Es, Fr & De

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Book Description :

A Key Regulator of Postnatal Skeletal Remodeling.- Ectodomain Shedding of Receptor Activator of NF-KB Ligand.- The Negative Role Of Ids In Osteoclastogenesis.- Functional Genetic and Genomic Analysis of Modeled Arthritis.- Dexamethsone Suppresses Bone Formation via the Osteoclast.- Immunologic Regulation Of Bone Development.- Pth Regulates The Hematopoietic Stem Cell Niche In Bone.- Regulation Of Hematopoietic Stem Cells In The Osteoblastic Niche.- The Chemokine Cxcl12 And Regulation Of Hsc And Lymphocyte Development In The Bone Marrow Niche.- Osteoclast Precursor Cells.- Interaction with estrogen receptors as treatment of arthritis and osteoporosis.- Novel Signaling Pathways And Therapeutic Targets In Osteoclasts.- The Enigmatic Function of TREM-2 in Osteoclastogenesis.- Role of cell-matrix interactions in osteoclast differentiation.- Positive and negative roles of IL-6, STAT3 and SOCS3 in inflammatory arthritis.- Control of Osteoclast activity and bone loss by IKK subunits: new targets for therapy.- Targeting Osteoporosis And Rheumatoid Arthritis By Active Vaccination Against Rankl.- RANKL Inhibition: From Mice to Men (and Women).

Advances in Osteoimmunology

Advances in Osteoimmunology Book
Author : Claudine Blin-Wakkach,Teun J. de Vries
Publisher : Frontiers Media SA
Release : 2020-01-21
ISBN : 2889633241
Language : En, Es, Fr & De

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Book Description :

Download Advances in Osteoimmunology book written by Claudine Blin-Wakkach,Teun J. de Vries, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Principles of Osteoimmunology

Principles of Osteoimmunology Book
Author : Peter Pietschmann
Publisher : Springer
Release : 2016-08-18
ISBN : 331934238X
Language : En, Es, Fr & De

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Book Description :

This fully updated and extended second edition provides a comprehensive overview on the basic concepts of the rapidly developing field of osteoimmunology and also offers in-depth insights into the molecular mechanisms of bone diseases. Clinical data is presented and put into context with the latest research findings. This second edition in addition discusses the latest topics in transplantation immunology. The book addresses scientists and physicians working in immunology, pathophysiology and osteology.

Innate Immunity in the Context of Osteoimmunology 2nd Edition

Innate Immunity in the Context of Osteoimmunology  2nd Edition Book
Author : Cristina Sobacchi,Anita Ignatius
Publisher : Frontiers Media SA
Release : 2021-07-01
ISBN : 2889669491
Language : En, Es, Fr & De

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Book Description :

We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS. Part of the APCs for articles in this collection were financed by the Fondazione Beppe e Nuccy Angiolini ONLUS. Publisher’s note: In this 2nd edition, acknowledgment for the Fondazione Beppe e Nuccy Angiolini ONLUS has been added.

Recent Advances in Basic and Translational Osteoimmunology

Recent Advances in Basic and Translational Osteoimmunology Book
Author : Rupesh K. Srivastava,Naibedya Chattopadhyay,Katharina Schmidt-Bleek,Pradyumna Kumar Mishra,Massimo De Martinis
Publisher : Frontiers Media SA
Release : 2022-01-10
ISBN : 2889740145
Language : En, Es, Fr & De

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Book Description :

Download Recent Advances in Basic and Translational Osteoimmunology book written by Rupesh K. Srivastava,Naibedya Chattopadhyay,Katharina Schmidt-Bleek,Pradyumna Kumar Mishra,Massimo De Martinis, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Updates on Osteoimmunology What s New on the Crosstalk Between Bone and Immune Cells

Updates on Osteoimmunology  What   s New on the Crosstalk Between Bone and Immune Cells Book
Author : Giacomina Brunetti,Patrizia D’Amelio,Giorgio Mori,Maria Felicia Faienza
Publisher : Frontiers Media SA
Release : 2020-03-24
ISBN : 2889636135
Language : En, Es, Fr & De

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Book Description :

Download Updates on Osteoimmunology What s New on the Crosstalk Between Bone and Immune Cells book written by Giacomina Brunetti,Patrizia D’Amelio,Giorgio Mori,Maria Felicia Faienza, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Osteoimmunology

Osteoimmunology Book
Author : Yongwon Choi
Publisher : Springer Science & Business Media
Release : 2007-10-01
ISBN : 0387720081
Language : En, Es, Fr & De

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Book Description :

A Key Regulator of Postnatal Skeletal Remodeling.- Ectodomain Shedding of Receptor Activator of NF-KB Ligand.- The Negative Role Of Ids In Osteoclastogenesis.- Functional Genetic and Genomic Analysis of Modeled Arthritis.- Dexamethsone Suppresses Bone Formation via the Osteoclast.- Immunologic Regulation Of Bone Development.- Pth Regulates The Hematopoietic Stem Cell Niche In Bone.- Regulation Of Hematopoietic Stem Cells In The Osteoblastic Niche.- The Chemokine Cxcl12 And Regulation Of Hsc And Lymphocyte Development In The Bone Marrow Niche.- Osteoclast Precursor Cells.- Interaction with estrogen receptors as treatment of arthritis and osteoporosis.- Novel Signaling Pathways And Therapeutic Targets In Osteoclasts.- The Enigmatic Function of TREM-2 in Osteoclastogenesis.- Role of cell-matrix interactions in osteoclast differentiation.- Positive and negative roles of IL-6, STAT3 and SOCS3 in inflammatory arthritis.- Control of Osteoclast activity and bone loss by IKK subunits: new targets for therapy.- Targeting Osteoporosis And Rheumatoid Arthritis By Active Vaccination Against Rankl.- RANKL Inhibition: From Mice to Men (and Women).

Osteoimmunology

Osteoimmunology Book
Author : Joseph Lorenzo,Mark Horowitz,Yongwon Choi,Hiroshi Takayanagi
Publisher : Academic Press
Release : 2010-09-24
ISBN : 9780123756718
Language : En, Es, Fr & De

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Book Description :

Bone and the immune system are both complex tissues, which, respectively, regulate the skeleton and the body's responses to invading pathogens. Critical interactions between these two organ systems frequently occur, particularly in the development of immune cells in the bone marrow and for the function of bone cells in health and disease. This book provides a detailed overview of the many ways that bone and immune cells interact. The goal is to provide basic and clinical scientists with a better understanding of the role that the immune system and bone play in the development and function of each other so that advances in both fields will be facilitated. The focus of the book will be both on basic pathways and translational science, which will apply basic knowledge to clinical diseases. Chapter content will range from basic descriptions of the various cell systems and their development to the signals that cause them to interact during normal physiology and disease. This is a rapidly developing area that is of interest to a wide spectrum of researchers, students, and fellows in immunology, rheumatology, hematology, and bone biology--all of whom need to develop a more complete understanding of their previously separate disciplines and the mechanisms by which they interact. Presents a comprehensive, translational source for all aspects of osteoimmunology in one reference work Experts in bone biology and immunology (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches. Clear presentations by bone biologists of the cellular and molecular mechanisms underlying bone cell development leading to bone and immunological diseases such as Lupus Clear presentations by immunologists of how immune cells develop and how the immune system plays a role in bone diseases like osteoporosis and arthritis

The Immune Response to Implanted Materials and Devices

The Immune Response to Implanted Materials and Devices Book
Author : Bruna Corradetti
Publisher : Springer
Release : 2016-11-30
ISBN : 3319454331
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.

Osteoimmunopathology

Osteoimmunopathology Book
Author : Francesco Chiappelli
Publisher : Springer Science & Business Media
Release : 2011-05-30
ISBN : 1441994955
Language : En, Es, Fr & De

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Book Description :

Osteoimmunology pertains to the study of the relationship between the bones, particularly the bone marrow, and the immune system. This monograph pursues the best available evidence, by means of research synthesis, for the characterization of the physiological relevance and pathological implications of the inter-connectedness between the skeletal and the immune system. Research will be discussed that highlights the associated role of the circulatory, nervous and endocrine systems, as well as proteomic and genomic pathways and signatures. Emphasis is given that domain of medicine that relates to the oral cavity, its diseases and their systemic sequelae. This monograph arises from observations that have suggested that the skeletal system and the immune system are intimately intertwined. Chronic inflammatory reactions subsequent to an excessive immune reaction can damage the bones, as in rheumatoid arthritis (RA), osteoporosis, patients seropositive for the human immunodeficiency virus (HIV)-1 and with signs and symptoms of the acquired immune deficiency syndrome (AIDS), and bone cancer. Bones – in particular the bone marrow – are one of the primary locations in which cells of the immune system mature. In brief, this monograph begins to answer a range of questions, such as, what is osteoimmunology all about?, does the immune system and its components affect bone development?, how do stress hormones impact upon the pathophysiology of bone-immune interactions?, can the scientific process of research synthesis, obtain the best available evidence for treatment of diseases involving the bone-immune entity (i.e., osteo immunopathologies) means of evidence-based clinical decision-making directed at the treatment of osteoimmune pathologies?

Osteoimmunology

Osteoimmunology Book
Author : Yongwon Choi
Publisher : Springer Science & Business Media
Release : 2009-12-01
ISBN : 9781441910509
Language : En, Es, Fr & De

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Book Description :

It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone, the normal development of the hematopoietic and immune systems and provide niche for long-term memory B and T cells. In the past scientists involved in immune and bone cell investigations have rarely interacted in a significant way as these disciplines have developed independently and, for the most part, remain separate. The conference will bring together leading international scientists from both fields to interact so that new collaboration can develop and more rapid progress in understanding the relationships between these fields can be achieved. Short talks will be selected from abstracts from the international community. This conference will have a format to provide an environment of maximum interaction and interchange through lectures, posters, and open discussion.

Rheumatology E Book

Rheumatology E Book Book
Author : Marc C. Hochberg,Alan J. Silman,Josef S. Smolen,Michael E. Weinblatt,Michael H. Weisman
Publisher : Elsevier Health Sciences
Release : 2014-06-16
ISBN : 0702063037
Language : En, Es, Fr & De

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Book Description :

Stay current in the ever-changing discipline of rheumatology with clear, reliable guidance from Hochberg’s Rheumatology, one of the most respected and trusted sources in the field. Designed to meet the needs of the practicing clinician, this medical reference book provides extensive, authoritative coverage of rheumatic diseases from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Track disease progression and treat patients more effectively with the information on genetic findings, imaging outcomes, cell and biologic therapies, rheumatoid arthritis, and SLE. Incorporate recent findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics. Remain up to date on the latest information in rheumatology through 13 brand-new chapters covering biomedical and translation science, disease and outcome assessment, new imaging modalities, early emerging disease, clinical therapeutics, patient management, and rehabilitation. Take advantage of expanded coverage of small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. Focus on the core knowledge needed for successful results with each chapter co-authored by an internationally-renowned specialist in the field. Easily find the information you need thanks to a consistent, user-friendly format with templated content and large-scale images.

Editor s Pick 2021 Highlights in Signaling

Editor s Pick 2021  Highlights in Signaling Book
Author : Ana Cuenda
Publisher : Frontiers Media SA
Release : 2022-02-07
ISBN : 2889743470
Language : En, Es, Fr & De

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Book Description :

Download Editor s Pick 2021 Highlights in Signaling book written by Ana Cuenda, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Aging

Aging Book
Author : Shamim I. Ahmad
Publisher : CRC Press
Release : 2017-10-30
ISBN : 1315283883
Language : En, Es, Fr & De

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Book Description :

This book is a detailed and comprehensive synthesis of the scientific study of aging. Dozens of contributions from leading scholars review various theories of aging, and molecular, cellular, biochemical and microbial aspects of aging, among just a few of the topics included. Authoritative, wide ranging and thorough, this book will act as a source for experimental design, a comprehensive description of age related diseases, and provide information of the latest molecular theories underlying their causes. Additionally, it will target industries involved in developing anti-aging drugs, post-graduate medical students, and university libraries.

Bone Regulators and Osteoporosis Therapy

Bone Regulators and Osteoporosis Therapy Book
Author : Paula H. Stern
Publisher : Springer Nature
Release : 2020-11-28
ISBN : 3030573788
Language : En, Es, Fr & De

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Book Description :

This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments.

Osteosarcopenia

Osteosarcopenia Book
Author : Gustavo Duque,Bruce R. Troen
Publisher : Elsevier
Release : 2022-03-17
ISBN : 0128204206
Language : En, Es, Fr & De

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Book Description :

Falls, fractures, frailty, osteoporosis and sarcopenia are highly prevalent in older persons. While the concept of osteosarcopenia is new, it is a rapidly evolving and cross-disciplinary problem. Prevention and treatment are challenging and a combined therapeutic approach is needed. Osteosarcopenia provides evidence-based information on how to prevent and treat these conditions at multiple settings, including multiple illustrations, care pathways and tips to easily understand the pathophysiology, diagnostic methods and therapeutic approach to these conditions. This work evaluates the potential for a link between osteoporosis, sarcopenia and obesity. Presents diagnostic and therapeutic tips that facilitate the design and implementation of new care pathways, impacting the wellbeing of our older population Provides cross-disciplinary understanding by experts from the bone/osteoporosis field and the muscle/sarcopenia field Covers muscle and bone biology, mesenchymal stem cells, age-related changes and cross-talk between muscle, fat and bone, falls and fracture risk, glucose metabolism, diagnosis, imaging, and genetics of osteosarcopenia

Topics in Osteoporosis

Topics in Osteoporosis Book
Author : Margarita Valdés-Flores
Publisher : BoD – Books on Demand
Release : 2013-05-15
ISBN : 9535110667
Language : En, Es, Fr & De

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Book Description :

Osteoporosis affects the osteo-articular system. However, there are hormonal, kidney related, gastrointestinal and neuromuscular factors among other, that can be involved in the etiopathogenesis of the disease. In the other hand, for osteoporosis prevention there are many lifestyle conditions that are very important, as dietary habits, physical activity, drugs and caffeine intake, smoking, associated diseases, etc. Based on the above, treatment and prevention of osteoporosis have to be addressed in a multidisciplinary and integral approach. The knowledge about bone metabolism and the related disorders represents an extensive field that is currently increasing through many investigations conducted in the world. The purpose of this book is to show several reviews and original investigations related with osteoporosis.

Issues in National Regional and Environmental Health and Medicine 2011 Edition

Issues in National  Regional  and Environmental Health and Medicine  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464964610
Language : En, Es, Fr & De

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Book Description :

Issues in National, Regional, and Environmental Health and Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about National, Regional, and Environmental Health and Medicine. The editors have built Issues in National, Regional, and Environmental Health and Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about National, Regional, and Environmental Health and Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in National, Regional, and Environmental Health and Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.