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Organic Synthesis

Organic Synthesis Book
Author : Jürgen-Hinrich Fuhrhop,Guangtao Li
Publisher : John Wiley & Sons
Release : 2003-03-14
ISBN : 9783527302727
Language : En, Es, Fr & De

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Book Description :

Since it is one of the core disciplines, every student of organic chemistry will need to cover organic synthesis at some point. This third edition of an extremely well-received and proven textbook is specially written with advanced undergraduate and graduate students in mind, although it is equally useful for research chemists, too. 50% of the text is new and includes new chapters on combinatoric chemistry, non-covalent molecular assemblies and the use of the Internet for searching chemical compounds. The authors have chosen the methods included here for their efficiency, elegance, and didactic value and have highlighted important reactions within the text. From reviews of the second edition: 'The text is very readable, and the authors are especially gifted at explaining complex concepts clearly and succinctly...This book is highly recommended reading for anyone wishing to gain an overview of organic synthesis.' J. Am. Chem. Soc. With his preface, Noble prizewinner E. J. Corey has also endorsed this already highly acclaimed work.

Organic Synthesis

Organic Synthesis Book
Author : W A Smit,A F Bochkov,R Caple
Publisher : Royal Society of Chemistry
Release : 2007-10-31
ISBN : 1847551572
Language : En, Es, Fr & De

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Book Description :

The view of organic synthesis as "a concentrated expression of predictive ability and creative capacity" was advocated in the early 1950s. A concise and readable account of the role of synthesis in modern science, Organic Synthesis: The Science Behind the Art presents the general ideology of pursuits in the area of organic synthesis, and examines the methodologies that have evolved in the search for solutions to synthetic problems. This unique book details outstanding achievements of modern organic synthesis, not only for their scientific merits, but also for the aesthetic appeal of the target molecules chosen and the intrinsic beauty of the solutions to the problems posed. By judicious selection of data covering the main areas of synthetic explorations, this book serves to illustrate both the evolution of well-known approaches as well as recently emerged trends most likely to determine the future development of organic synthesis. Special attention is given to the consideration of principles of molecular design in promising and challenging areas of current research. Primarily aimed at advanced undergraduate and graduate students, Organic Synthesis: The Science Behind the Art will also be of interest to teachers, researchers and anyone requiring an introduction to the problems of organic synthesis.

Organic Synthesis

Organic Synthesis Book
Author : Paul Wyatt,Stuart Warren
Publisher : John Wiley & Sons
Release : 2013-05-20
ISBN : 1118681444
Language : En, Es, Fr & De

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Book Description :

Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren’s bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. A comprehensive, practical account of the key concepts involved in synthesising compounds Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations Focuses on reactions that really work rather than those with limited application Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.

Organic Synthesis

Organic Synthesis Book
Author : Michael B Smith
Publisher : Academic Press
Release : 2016-11-22
ISBN : 0128008075
Language : En, Es, Fr & De

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Book Description :

Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including Chapter Review Questions, and Homework Problems. PowerPoint© presentations and answer keys are also available online to support instructors. Fully revised and updated throughout, and teorganized into 19 chapters for a more cogent and versatile presentation of concepts Includes reaction examples taken from literature research reported between 2010-2015 Features new full-color art and new chapter content on process chemistry and green organic chemistry Offers valuable study and teaching tools, including Chapter Review Questions and Homework Problems for students; Lecture presentations and other useful material for qualified course instructors

Essential Reagents for Organic Synthesis

Essential Reagents for Organic Synthesis Book
Author : Philip L. Fuchs,André B. Charette,Tomislav Rovis,Jeffrey W. Bode
Publisher : John Wiley & Sons
Release : 2016-09-06
ISBN : 1119278309
Language : En, Es, Fr & De

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Book Description :

From Boron Trifluoride to Zinc, the 52 most widely used reagents in organic synthesis are described in this unique desktop reference for every organic chemist. The list of reagents contains classics such as N-Bromosuccinimide (NBS) and Trifluoromethanesulfonic Acid side by side with recently developed ones like Pinacolborane and Tetra-n-propylammonium Perruthenate (TPAP). For each reagent, a concise article provides a brief description of all important reactions for which the reagent is being used, including yields and reaction conditions, an overview of the physical properties of the reagent, its storage conditions, safe handling, laboratory synthesis and purification methods. Advantages and disadvantages of the reagent compared to alternative synthesis methods are also discussed. Reagents have been hand-picked from among the 5000 reagents contained in EROS, the Encyclopedia of Reagents for Organic Synthesis. Every organic chemist should be familiar with these key reagents that can make almost every reaction work.

Introduction to Strategies for Organic Synthesis

Introduction to Strategies for Organic Synthesis Book
Author : Laurie S. Starkey
Publisher : John Wiley & Sons
Release : 2018-05-01
ISBN : 1119347246
Language : En, Es, Fr & De

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Book Description :

Bridging the Gap Between Organic Chemistry Fundamentals and Advanced Synthesis Problems Introduction to Strategies of Organic Synthesis bridges the knowledge gap between sophomore-level organic chemistry and senior-level or graduate-level synthesis to help students more easily adjust to a synthetic chemistry mindset. Beginning with a thorough review of reagents, functional groups, and their reactions, this book prepares students to progress into advanced synthetic strategies. Major reactions are presented from a mechanistic perspective and then again from a synthetic chemist’s point of view to help students shift their thought patterns and teach them how to imagine the series of reactions needed to reach a desired target molecule. Success in organic synthesis requires not only familiarity with common reagents and functional group interconversions, but also a deep understanding of functional group behavior and reactivity. This book provides clear explanations of such reactivities and explicitly teaches students how to make logical disconnections of a target molecule. This new Second Edition of Introduction to Strategies for Organic Synthesis: Reviews fundamental organic chemistry concepts including functional group transformations, reagents, stereochemistry, and mechanisms Explores advanced topics including protective groups, synthetic equivalents, and transition-metal mediated coupling reactions Helps students envision forward reactions and backwards disconnections as a matter of routine Gives students confidence in performing retrosynthetic analyses of target molecules Includes fully-worked examples, literature-based problems, and over 450 chapter problems with detailed solutions Provides clear explanations in easy-to-follow, student-friendly language Focuses on the strategies of organic synthesis rather than a catalogue of reactions and modern reagents The prospect of organic synthesis can be daunting at the outset, but this book serves as a useful stepping stone to refresh existing knowledge of organic chemistry while introducing the general strategies of synthesis. Useful as both a textbook and a bench reference, this text provides value to graduate and advanced undergraduate students alike.

Organic Synthesis

Organic Synthesis Book
Author : Belakatte Parameshwarappa Nandeshwarappa
Publisher : BoD – Books on Demand
Release : 2020-05-27
ISBN : 1789859433
Language : En, Es, Fr & De

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Book Description :

The book ‘Organic Synthesis - A Nascent Relook’ is a compendium of the recent progress in all aspects of organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic, green chemistry and medicinal chemistry, polymer chemistry, as well as analytical methods in organic chemistry. The book presents the latest developments in these fields. The chapters are written by chosen experts who are internationally known for their eminent research contributions. Organic synthesis is the complete chemical synthesis of a target molecule. In this book, special emphasis is given to the synthesis of various bioactive heterocycles. Careful selection of various topics in this book will serve the rightful purpose for the chemistry community and the industrial houses at all levels.

Organic Synthesis

Organic Synthesis Book
Author : Michael Smith
Publisher : Academic Press
Release : 2010
ISBN : 1890661406
Language : En, Es, Fr & De

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Book Description :

The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to 'disconnect' a bigger molecule into simpler building blocks. Most chapters include an extensive list of questions to test the reader's understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists.

Towards Polymer Supported Iridium Borylation Catalysts for Organic Synthesis

Towards Polymer Supported Iridium Borylation Catalysts for Organic Synthesis Book
Author : Omar Abdullah Salih
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Towards Polymer Supported Iridium Borylation Catalysts for Organic Synthesis book written by Omar Abdullah Salih, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Organic Synthesis

Organic Synthesis Book
Author : Douglass F. Taber
Publisher : John Wiley & Sons
Release : 2006-08-18
ISBN : 0470056304
Language : En, Es, Fr & De

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Book Description :

The first in a new series, this book provides chemists an effective, much-needed way to stay abreast of recent developments in organic synthesis. The 103 articles review the leading synthetic procedures developed from 2003 - 2005, discussing their significance and their applications. More than 100 reactions are covered, including Heterocycle Construction by Grubbs Metathesis, Enantioselective C-C Bond Construction, and Organic Reactions in Ionic Liquids.

Modern Solvents in Organic Synthesis

Modern Solvents in Organic Synthesis Book
Author : J. Auge,B. Betzemeier
Publisher : Springer Science & Business Media
Release : 1999-10-08
ISBN : 9783540662136
Language : En, Es, Fr & De

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Book Description :

In recent years the choice of a given solvent for performing a reaction has become increasingly important. More and more, selective reagents are used for chemical transformations and the choice of the solvent may be determining for reaching high reaction rates and high selectivities. The toxicity and recycling considerations have also greatly influenced the nature of the solvents used for industrial reactions. Thus, the development of reactions in water is not only important on the laboratory scale but also for industrial applications. The p- formance of metal-catalyzed reactions in water for example has led to several new hydrogenation or hydroformylation procedures with important industrial applications. The various aspects of organic chemistry in water will be prese- ed in this book. Recently, novel reaction media such as perfluorinated solvents or supercritical carbon dioxide has proven to have unique advantages leading to more practical and more efficient reactions. Especially with perfluorinated solvents, new biphasic catalyses and novel approaches to perform organic reactions have been developed. These aspects will be examined in detail in this volume. Finally, the performance of reactions in the absence of solvents will show practical alternatives for many reactions. More than ever before, the choice of the solvent or the solvent system is ess- tial for realizing many chemical transformations with the highest efficiency. This book tries to cover the more recent and important new solvents or solvent systems for both academic and industrial applications.

Fiesers Reagents for Organic Synthesis

Fiesers  Reagents for Organic Synthesis Book
Author : Tse-Lok Ho
Publisher : John Wiley & Sons
Release : 2009-11-19
ISBN : 9780470551493
Language : En, Es, Fr & De

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Book Description :

The highly successful Fieser & Fieser series has provided several generations of professional chemists and students with an up-to-date survey of the reagent literature. Reagents are listed in alphabetical order by common name, and the brief entry tells how to make it or buy it, what it is good for, and where to find complete details. Volume 25 covers chemical literature from the beginning of 2007 to the end of June 2008.

Handbook of Organopalladium Chemistry for Organic Synthesis 2 Volume Set

Handbook of Organopalladium Chemistry for Organic Synthesis  2 Volume Set Book
Author : Ei-ichi Negishi
Publisher : John Wiley & Sons
Release : 2003-11-24
ISBN : 0471461555
Language : En, Es, Fr & De

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Book Description :

Download Handbook of Organopalladium Chemistry for Organic Synthesis 2 Volume Set book written by Ei-ichi Negishi, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Comprehensive Organic Synthesis Additions to and substitutions at C C pi Bonds

Comprehensive Organic Synthesis  Additions to and substitutions at C C pi  Bonds Book
Author : Barry M. Trost,M.F. Semmelhack,Ian Fleming
Publisher : Elsevier
Release : 1991
ISBN : 9780080405957
Language : En, Es, Fr & De

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Book Description :

Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.

Organic Synthesis

Organic Synthesis Book
Author : V. K. Ahluwalia,Renu Aggarwal
Publisher : CRC Press
Release : 2001
ISBN : 9780849310027
Language : En, Es, Fr & De

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Book Description :

Suitable for Master's and Ph.D. level students, as well as for the research scientist, this book describes the use of special techniques in organic synthesis and includes a brief discussion of the principles involved. It provides the methodology and procedures for typical preparations for each of the techniques.

Principles of Organic Synthesis

Principles of Organic Synthesis Book
Author : Richard O.C. Norman
Publisher : Routledge
Release : 2017-10-19
ISBN : 1351421727
Language : En, Es, Fr & De

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Book Description :

This book is designed for those who have had no more than a brief introduction to organic chemistry and who require a broad understanding of the subject. The book is in two parts. In Part I, reaction mechanism is set in its wider context of the basic principles and concepts that underlie chemical reactions: chemical thermodynamics, structural theory, theories of reaction kinetics, mechanism itself and stereochemistry. In Part II these principles and concepts are applied to the formation of particular types of bonds, groupings, and compounds. The final chapter in Part II describes the planning and detailed execution of the multi-step syntheses of several complex, naturally occurring compounds.

Advances in Organic Synthesis

Advances in Organic Synthesis Book
Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
Release : 2013-03-27
ISBN : 1608050297
Language : En, Es, Fr & De

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Book Description :

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. It presents comprehensive articles written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations. Contributions are written by eminent scientists and each volume is edited by an authority in the field. Advances in Organic Synthesis is essential for all organic chemists in the academia and industry who wish to keep abreast of rapid and important developments in the field.

Greene s Protective Groups in Organic Synthesis

Greene s Protective Groups in Organic Synthesis Book
Author : Peter G. M. Wuts,Theodora W. Greene
Publisher : John Wiley & Sons
Release : 2012-12-20
ISBN : 1118589327
Language : En, Es, Fr & De

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Book Description :

Download Greene s Protective Groups in Organic Synthesis book written by Peter G. M. Wuts,Theodora W. Greene, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Solvent free Organic Synthesis

Solvent free Organic Synthesis Book
Author : Koichi Tanaka
Publisher : John Wiley & Sons
Release : 2006-03-06
ISBN : 3527605363
Language : En, Es, Fr & De

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Book Description :

The demand for increasingly clean and efficient chemical syntheses is continuously becoming more urgent from both an economic and an environmental standpoint. So-called green technologies are looking for alternatives, yet they focus on large quantities of hazardous even toxic solvents. One could even say that the best solvent is no solvent. It is against this background that chemical synthesis without the use of solvents has increasingly developed into a powerful methodology. Once the chemical reactivity is increased, the amount of initial substances needed is reduced; in particular it removes the need for the complex recycling and disposal of solvents. In this book, the third in our open "Green Chemistry" series, Koichi Tanaka describes the latest developments in this exciting field. Packed with advice on applications, this will be equally useful to practitioners in research as well as process chemists in industry, such that it is sure to become an invaluable reference source.