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Organic Chemistry Concepts And Applications For Medicinal Chemistry

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Organic Chemistry Concepts and Applications for Medicinal Chemistry

Organic Chemistry Concepts and Applications for Medicinal Chemistry Book
Author : Joseph E. Rice
Publisher : Academic Press
Release : 2014-04-14
ISBN : 0128008326
Language : En, Es, Fr & De

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Book Description :

Organic Chemistry Concepts and Applications for Medicinal Chemistry provides a valuable refresher for understanding the relationship between chemical bonding and those molecular properties that help to determine medicinal activity. This book explores the basic aspects of structural organic chemistry without going into the various classes of reactions. Two medicinal chemistry concepts are also introduced: partition coefficients and the nomenclature of cyclic and polycyclic ring systems that comprise a large number of drug molecules. Given the systematic name of a drug, the reader is guided through the process of drawing an accurate chemical structure. By emphasizing the relationship between structure and properties, this book gives readers the connections to more fully comprehend, retain, apply, and build upon their organic chemistry background in further chemistry study, practice, and exams. Focused approach to review those organic chemistry concepts that are most important for medicinal chemistry practice and understanding Accessible content to refresh the reader's knowledge of bonding, structure, functional groups, stereochemistry, and more Appropriate level of coverage for students in organic chemistry, medicinal chemistry, and related areas; individuals seeking content review for graduate and medical courses and exams; pharmaceutical patent attorneys; and chemists and scientists requiring a review of pertinent material

Concepts and Applications of Organic Chemistry

Concepts and Applications of Organic Chemistry Book
Author : Saul Rowen
Publisher : Unknown
Release : 2017-05-16
ISBN : 9781632385512
Language : En, Es, Fr & De

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Book Description :

Since twentieth century, organic chemistry emerged and has been rapidly expanding throughout without deceleration in the progress of this field. Foundations of medicine and biotechnology are built on organic compounds. It is contributing to the research in medicinal chemistry, polymer chemistry, as well as several aspects of materials science. This book discusses the fundamentals and concentrates on the applications of organic chemistry. It presents the concepts and applications in a concise manner for a better understanding of the subject. Students, researchers, experts and all associated with organic chemistry will benefit alike from this book.

Medicinal Chemistry

Medicinal Chemistry Book
Author : Erica Helmer
Publisher : Unknown
Release : 2016-05-27
ISBN : 9781682860960
Language : En, Es, Fr & De

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Book Description :

Medicinal chemistry is an evolving field of science that deals with the development and design of pharmaceutical drugs. It has aided the discovery and development of new drugs for curing severe diseases. The main objective of this book is to give a general overview of different areas of synthetic organic chemistry, structural biology, chemical biology, etc. This book will prove to be beneficial for students and professionals alike.

Green Techniques for Organic Synthesis and Medicinal Chemistry

Green Techniques for Organic Synthesis and Medicinal Chemistry Book
Author : Wei Zhang,Berkeley W. Cue
Publisher : John Wiley & Sons
Release : 2018-03-19
ISBN : 1119288169
Language : En, Es, Fr & De

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Book Description :

An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.

Medicinal Chemistry Concepts and Applications

Medicinal Chemistry  Concepts and Applications Book
Author : Thomas Haldane
Publisher : Unknown
Release : 2018-02-26
ISBN : 9781632385864
Language : En, Es, Fr & De

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Book Description :

Medicinal chemistry studies the design and development of pharmaceutical drugs. It is a multi-disciplinary subject that combines pharmacology, synthetic organic chemistry, toxicology, molecular biology, etc. Discovery of newer pharmaceutical agents by studying existing drugs with pathological or biological targets is the main concern of this field. Performing clinical trials and assessing the effectiveness of drugs is another significant facet of medicinal chemistry. The topics covered in this extensive book deal with the core aspects of medicinal chemistry. It aims to equip students and experts with the advanced topics and upcoming concepts in this area.

Frontiers in Computational Chemistry Volume 5

Frontiers in Computational Chemistry  Volume 5 Book
Author : Zaheer-Ul-Haq,Angela K. Wilson
Publisher : Bentham Science Publishers
Release : 2020-09-11
ISBN : 9811457778
Language : En, Es, Fr & De

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Book Description :

Frontiers in Computational Chemistry presents contemporary research on molecular modeling techniques used in drug discovery and the drug development process: computer aided molecular design, drug discovery and development, lead generation, lead optimization, database management, computer and molecular graphics, and the development of new computational methods or efficient algorithms for the simulation of chemical phenomena including analyses of biological activity. The fifth volume of this series features these six chapters: - Recent Advances and Role of Computational Chemistry in Drug Designing and Development on Viral Diseases - Molecular Modeling Applied to Design of Cysteine Protease Inhibitors – A Powerful Tool for the Identification of Hit Compounds Against Neglected Tropical Diseases - Application of Systems Biology Methods in Understanding the Molecular Mechanism of Signalling Pathways in the Eukaryotic System - Implementation of the Molecular Electrostatic Potential over GPUs: Large Systems as Main Target - Molecular Electron Density Theory: A New Theoretical Outlook on Organic Chemistry - Frontier Molecular Orbital Approach to the Cycloaddition Reactions

Physico chemical Aspects of Textile Coloration

Physico chemical Aspects of Textile Coloration Book
Author : Stephen M. Burkinshaw
Publisher : John Wiley & Sons
Release : 2016-02-08
ISBN : 1118725697
Language : En, Es, Fr & De

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Book Description :

The production of textile materials comprises a very large and complex global industry that utilises a diverse range of fibre types and creates a variety of textile products. As the great majority of such products are coloured, predominantly using aqueous dyeing processes, the coloration of textiles is a large-scale global business in which complex procedures are used to apply different types of dye to the various types of textile material. The development of such dyeing processes is the result of substantial research activity, undertaken over many decades, into the physico-chemical aspects of dye adsorption and the establishment of ‘dyeing theory’, which seeks to describe the mechanism by which dyes interact with textile fibres. Physico-Chemical Aspects of Textile Coloration provides a comprehensive treatment of the physical chemistry involved in the dyeing of the major types of natural, man-made and synthetic fibres with the principal types of dye. The book covers: fundamental aspects of the physical and chemical structure of both fibres and dyes, together with the structure and properties of water, in relation to dyeing; dyeing as an area of study as well as the terminology employed in dyeing technology and science; contemporary views of intermolecular forces and the nature of the interactions that can occur between dyes and fibres at a molecular level; fundamental principles involved in dyeing theory, as represented by the thermodynamics and kinetics of dye sorption; detailed accounts of the mechanism of dyeing that applies to cotton (and other cellulosic fibres), polyester, polyamide, wool, polyacrylonitrile and silk fibres; non-aqueous dyeing, as represented by the use of air, organic solvents and supercritical CO2 fluid as alternatives to water as application medium. The up-to-date text is supported by a large number of tables, figures and illustrations as well as footnotes and widespread use of references to published work. The book is essential reading for students, teachers, researchers and professionals involved in textile coloration.

Textbook of Organic Medicinal and Pharmaceutical Chemistry

Textbook of Organic Medicinal and Pharmaceutical Chemistry Book
Author : Charles Owens Wilson,Ole Gisvold,Robert F. Doerge
Publisher : Lippincott Williams & Wilkins
Release : 1977
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Textbook of Organic Medicinal and Pharmaceutical Chemistry book written by Charles Owens Wilson,Ole Gisvold,Robert F. Doerge, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Principles of Organic Medicinal Chemistry

Principles of Organic Medicinal Chemistry Book
Author : Rama Rao Nadendla
Publisher : New Age International
Release : 2007
ISBN : 8122415717
Language : En, Es, Fr & De

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Book Description :

The Book Principles Of Organic Medicinal Chemistry Describes The Principles And Concepts Of Chemistry, Synthetic Schemes, Structure Activity Relationships, Mechanism Of Action And Clinical Uses Of Carbon Compounds In The Light Of Modern Trends. The Book Covers The Syllabai Of B. Pharmacy And M.Pharmacy Courses Of All Indian Universities.This Book Comprises Of 22 Chapters. Chapter 1 Gives An Introduction To Medicinal Chemistry, Chapter 2 Explain About The Basics On Principles Of Drug Action And Physicochemical Properties Of Organic Medicinal, Substances Are Elaborated In Chapter 3. The Concepts Of Prodrugs And Drug Metabolism Are Summarized In Chapter 4 And Chapter 5 Respectively. Chapter 6 To Chapter 22 Explains Chemistry, Properties, Mechanism Of Action, Structure Activity Relationships, Chemistry Of Newer Drugs And Clinical Uses Of Various Therapeutic Agents. At The End Of Book, A Set Of More Than 200 Essays And Short Questions And 225 Objective Questions With Answers Are St Strategically Designed.

Selected Topics in Organic Chemistry

Selected Topics in Organic Chemistry Book
Author : Francesca Hopkins
Publisher : Murphy & Moore Publishing
Release : 2021-11-16
ISBN : 9781639874989
Language : En, Es, Fr & De

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Book Description :

The branch of chemistry that includes the study of structures, properties, composition, reaction and preparation of organic compounds is known as organic chemistry. Organic compounds are covalently bonded carbon containing compounds including hydrogen, halogen and other elements. They are classified on the basis of functional groups, aliphatic groups, aromaticity and the size of molecule. Organic compounds are structurally diverse and form the functional and structural basis of all living beings and many commercial products. Organic chemistry is an umbrella science which overlaps organometallic chemistry, biochemistry, medicinal chemistry, materials science and polymer chemistry. Organic chemistry is applied in a large number of industries such as pharmaceutical industry, petroleum industry, and chemical industry. This book traces the progress of this field and highlights some of its key concepts and applications. The topics included in this book on organic chemistry are of utmost significance and bound to provide incredible insights to readers. It aims to serve as a resource guide for students and experts alike and contribute to the growth of the discipline.

Principles of Organic Chemistry

Principles of Organic Chemistry Book
Author : Robert J. Ouellette,J. David Rawn
Publisher : Academic Press
Release : 2015-02-13
ISBN : 0128026340
Language : En, Es, Fr & De

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Book Description :

Class-tested and thoughtfully designed for student engagement, Principles of Organic Chemistry provides the tools and foundations needed by students in a short course or one-semester class on the subject. This book does not dilute the material or rely on rote memorization. Rather, it focuses on the underlying principles in order to make accessible the science that underpins so much of our day-to-day lives, as well as present further study and practice in medical and scientific fields. This book provides context and structure for learning the fundamental principles of organic chemistry, enabling the reader to proceed from simple to complex examples in a systematic and logical way. Utilizing clear and consistently colored figures, Principles of Organic Chemistry begins by exploring the step-by-step processes (or mechanisms) by which reactions occur to create molecular structures. It then describes some of the many ways these reactions make new compounds, examined by functional groups and corresponding common reaction mechanisms. Throughout, this book includes biochemical and pharmaceutical examples with varying degrees of difficulty, with worked answers and without, as well as advanced topics in later chapters for optional coverage. Incorporates valuable and engaging applications of the content to biological and industrial uses Includes a wealth of useful figures and problems to support reader comprehension and study Provides a high quality chapter on stereochemistry as well as advanced topics such as synthetic polymers and spectroscopy for class customization

Medicinal Chemistry an Introduction

Medicinal Chemistry  an Introduction Book
Author : Oakely Webster
Publisher : Unknown
Release : 2017-05-15
ISBN : 9781635491814
Language : En, Es, Fr & De

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Book Description :

This book elucidates the concepts and innovative models around prospective developments with respect to medicinal chemistry. It talks in detail about the various concepts and important aspects of this field. Medicinal chemistry refers to the amalgamation of synthetic organic chemistry pharmacology in order to create and design better medicinal drugs. It combines branches like molecular biology, pharmacology, human medicine, toxicology, chemical biology, structural biology, etc. Most of the topics introduced in this text cover new techniques and the applications of medicinal biology. While understanding the long-term perspectives of the topics, the book makes an effort in highlighting their impact as a modern tool for the growth of the discipline. The text is an essential guide for both academicians and those who wish to pursue this discipline further.

Applied Organic Chemistry

Applied Organic Chemistry Book
Author : Surya K. De
Publisher : John Wiley & Sons
Release : 2021-03-08
ISBN : 3527347852
Language : En, Es, Fr & De

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Book Description :

An indispensable guide for all synthetic chemists who want to learn about the most relevant reactions and reagents employed to synthesize important heterocycles and drugs! The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin. Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry. Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry. Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin. Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area. User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions. Applied Organic Chemistry is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.

Current Catalog

Current Catalog Book
Author : National Library of Medicine (U.S.)
Publisher : Unknown
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

First multi-year cumulation covers six years: 1965-70.

Medicinal Chemistry

Medicinal Chemistry Book
Author : Thomas Nogrady,Donald F. Weaver
Publisher : Oxford University Press
Release : 2005-08-11
ISBN : 9780195104554
Language : En, Es, Fr & De

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Book Description :

Fully updated, this textbook takes a receptor-based, target-centred approach, presenting concepts central to the study of drug action in a logical, mechanistic way, grounded on molecular & biochemical principles.

Chemistry for Pharmacy Students

Chemistry for Pharmacy Students Book
Author : Lutfun Nahar,Professor Satyajit D. Sarker
Publisher : John Wiley & Sons
Release : 2019-08-26
ISBN : 1119394430
Language : En, Es, Fr & De

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Book Description :

Introduces the key areas of chemistry required for all pharmacy degree courses and focuses on the properties and actions of drug molecules This new edition provides a clear and comprehensive overview of the various areas of general, organic, and natural products chemistry (in relation to drug molecules). Structured to enhance student understanding, it places great emphasis on the applications of key theoretical aspects of chemistry required by all pharmacy and pharmaceutical science students. This second edition particularly caters for the chemistry requirements in any ‘Integrated Pharmacy Curricula’, where science in general is meant to be taught ‘not in isolation’, but together with, and as a part of, other practice and clinical elements of the course. Chemistry for Pharmacy Students: General, Organic and Natural Product Chemistry, 2nd Edition is divided into eight chapters. It opens with an overview of the general aspects of chemistry and their importance to modern life, with emphasis on medicinal applications. The text then moves on to discuss the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy in relation to drug action and toxicity. Various aspects of organic functional groups, organic reactions, heterocyclic chemistry, nucleic acids and their pharmaceutical importance are then covered in subsequent chapters, with the final chapter dealing with drug discovery and development, and natural product chemistry. Provides a student-friendly introduction to the main areas of chemistry required by pharmacy degree courses Written at a level suitable for non-chemistry students in pharmacy, but also relevant to those in life sciences, food science, and the health sciences Includes learning objectives at the beginning of each chapter Focuses on the physical properties and actions of drug molecules Chemistry for Pharmacy Students: General, Organic and Natural Product Chemistry, 2nd Edition is an essential book for pharmacy undergraduate students, and a helpful resource for those studying other subject areas within pharmaceutical sciences, biomedical sciences, cosmetic science, food sciences, and health and life sciences.

Fundamentals of Heterocyclic Chemistry

Fundamentals of Heterocyclic Chemistry Book
Author : Louis D. Quin,John A. Tyrell
Publisher : John Wiley & Sons
Release : 2010-07-08
ISBN : 9780470626535
Language : En, Es, Fr & De

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Book Description :

Heterocyclic chemistry is of prime importance as a sub-discipline of Organic Chemistry, as millions of heterocyclic compounds are known with more being synthesized regularly Introduces students to heterocyclic chemistry and synthesis with practical examples of applied methodology Emphasizes natural product and pharmaceutical applications Provides graduate students and researchers in the pharmaceutical and related sciences with a background in the field Includes problem sets with several chapters

Understanding Medicinal Plants

Understanding Medicinal Plants Book
Author : Bryan Hanson
Publisher : Routledge
Release : 2013-01-11
ISBN : 1136614869
Language : En, Es, Fr & De

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Book Description :

Learn how medicinal plants work from the chemical level upward Understanding Medicinal Plants: Their Chemistry and Therapeutic Action is designed to teach the chemical concepts necessary to understand the actions of medicinal plants to people who are intimidated by chemistry. This beautifully illustrated, accessibly written guide explores the molecules of medicinal plants and the pharmacology behind their actions on the human body. The book will be valuable to non-science majors, biology majors, interested scientists of different disciplines, and practitioners and students of herbalism and complementary medicine. Understanding Medicinal Plants covers the essentials, including: understanding the symbolism of chemical structure bonding—and predicting useful properties important plant compounds isolation and purification of plant molecules drug delivery and action in the human body the chemistry of antioxidants identification of plant molecules Interest in alternative medicine and herbal products has never been higher than it is now. Understanding Medicinal Plants aims for the middle ground between technical manuals for highly trained individuals and books for the general public that may oversimplify the material. This introductory work provides you with a wealth of suggested reading materials, tables, figures, and illustrations. Three case studies illustrate specific plant drugs and their molecular constituents. This resource also provides an extensive glossary for easy reference. In Understanding Medicinal Plants, you will find a lexicon of medicinally important chemical families found in plants to help you identify and understand the role of constituents such as: alkaloids flavonoids coumarins glycosides amino acids lignans tannins and many more Understanding Medicinal Plants enriches your knowledge of the science behind herbalism and increases your savvy as a consumer of herbal products. This sourcebook will help you better understand the debates about the regulation of medicinal plants and related health care policy debates. With this book, you will be able to interpret media hype about medicinal plants with greater confidence.

Phosphorus Ylides

Phosphorus Ylides Book
Author : Oleg I. Kolodiazhnyi
Publisher : John Wiley & Sons
Release : 2008-09-26
ISBN : 3527613919
Language : En, Es, Fr & De

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Book Description :

When Wittig first developed and described phosphorus ylides, nobody could have imagined how useful and versatile this class of compounds could be. This book provides a comprehensive and up-to-date compilation of the chemistry and applications of phosphorus ylides in organic synthesis. The ylides are discussed as reagents in the synthesis of a broad range of substances, amongst them olefins, acetylenes, cyclic and heterocyclic compounds, in such naturally occurring compounds as pheromones, steroids and carotenoids, and pharmaceutically and biologically active compounds such as antibiotics and prostaglandins. A particularly beneficial feature of this book is the 150 key experimental procedures with all the necessary data, allowing the preparation to start immediately without the need for an extremely time-consuming literature search. But should a search prove inevitable, around 2,500 references provide easy access to the primary literature. Every chemist in academia and industry working in organic, bioorganic, inorganic, and medicinal chemistry will welcome this book as an inspiration of concepts, ideas and practical syntheses.

Review of Organic Functional Groups

Review of Organic Functional Groups Book
Author : Thomas L. Lemke
Publisher : Unknown
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Review of Organic Functional Groups book written by Thomas L. Lemke, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.