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Ode Pde Analysis Of Antibiotic Antimicrobial Resistance

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ODE PDE Analysis of Antibiotic Antimicrobial Resistance

ODE PDE Analysis of Antibiotic Antimicrobial Resistance Book
Author : William E. Schiesser
Publisher : Academic Press
Release : 2020-08-24
ISBN : 0128242507
Language : En, Es, Fr & De

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Book Description :

Mathematical models for antibiotic/antimicrobial resistance based on ordinary and partial differential equations (ODE/PDEs) are presented in this book, starting with a basic ODE model in Chapter 1, and concluding with a detailed PDE model in Chapters 4 and 5 that gives the spatiotemporal distribution of four dependent variable components: (1) susceptible bacteria population density, (2) resistant bacteria population density, (3) plasmid number, and (4) antibiotic concentration. The computer-based implementation of the example models is presented through routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized, e.g., no theorems and proofs. Rather, the presentation is through detailed examples that the reader/researcher/analyst can execute on modest computers. The PDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs, implemented with finite differences. The routines are available from a download link so that the example models can be executed without having to first study numerical methods and computer coding. The routines can then be applied to variations and extensions of the antibiotic/antimicrobial models, such as changes in the ODE/PDE parameters (constants) and the form of the model equations. Includes PDE routines based on the method of lines (MOL) for computer-based implementation of PDE models Offers transportable computer source codes for readers in R, with line-by-line code descriptions as it relates to the mathematical model and algorithms Authored by a leading researcher and educator in PDE models

Systems Medicine

Systems Medicine Book
Author : Anonim
Publisher : Academic Press
Release : 2020-08-24
ISBN : 0128160780
Language : En, Es, Fr & De

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Book Description :

Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice. Encyclopedic coverage: ‘one-stop’ resource for access to information written by world-leading scholars in the field of Systems Biology and Systems Medicine, with easy cross-referencing of related articles to promote understanding and further research Authoritative: the whole work is authored and edited by recognized experts in the field, with a range of different expertise, ensuring a high quality standard Digitally innovative: Hyperlinked references and further readings, cross-references and diagrams/images will allow readers to easily navigate a wealth of information

Government Reports Announcements Index

Government Reports Announcements   Index Book
Author : Anonim
Publisher : Unknown
Release : 1988-07
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Government Reports Announcements Index book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Science Citation Index

Science Citation Index Book
Author : Anonim
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Vols. for 1964- have guides and journal lists.