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Ode Pde α Synuclein Models For Parkinsons Disease

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ODE PDE synuclein Models for Parkinson s Disease

ODE PDE    synuclein Models for Parkinson s Disease Book
Author : William E. Schiesser
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download ODE PDE synuclein Models for Parkinson s Disease book written by William E. Schiesser, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

ODE PDE synuclein Models for Parkinson s Disease

ODE PDE    synuclein Models for Parkinson   s Disease Book
Author : William E. Schiesser
Publisher : Academic Press
Release : 2018-02-13
ISBN : 0128148020
Language : En, Es, Fr & De

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Book Description :

ODE/PDE Alpha-Synuclein Models for Parkinson’s Disease discusses a mechanism for the evolution of Parkinson’s Disease (PD) based on the dynamics of the protein α-synuclein, a monomer that has been implicated in this disease. Specifically, α-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the α-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest. This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms Includes PDE routines based on the method of lines (MOL) for computer-based implementation of ODE/PDE models Offers transportable computer source codes for readers, with line-by-line code descriptions relating to the mathematical model and algorithms Authored by a leading researcher and educator in ODE/PDE models

ODE PDE Alpha Synuclein Models for Parkinson s Disease

ODE   PDE Alpha Synuclein Models for Parkinson s Disease Book
Author : William E. Schiesser
Publisher : Academic Press
Release : 2018-02-14
ISBN : 9780128146149
Language : En, Es, Fr & De

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Book Description :

ODE/PDE Alpha-Synuclein Models for Parkinson's Disease discusses a mechanism for the evolution of Parkinson's Disease (PD) based on the dynamics of the protein α-synuclein, a monomer that has been implicated in this disease. Specifically, α-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the α-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest. This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms Includes PDE routines based on the method of lines (MOL) for computer-based implementation of ODE/PDE models Offers transportable computer source codes for readers, with line-by-line code descriptions relating to the mathematical model and algorithms Authored by a leading researcher and educator in ODE/PDE models

Society for Neuroscience Abstracts

Society for Neuroscience Abstracts Book
Author : Society for Neuroscience. Meeting
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Society for Neuroscience Abstracts book written by Society for Neuroscience. Meeting, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

5th International Conference on Biomedical Engineering in Vietnam

5th International Conference on Biomedical Engineering in Vietnam Book
Author : Vo Van Toi,Tran Ha Lien Phuong
Publisher : Springer
Release : 2014-11-18
ISBN : 3319117769
Language : En, Es, Fr & De

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Book Description :

This volume presents the proceedings of the Fifth International Conference on the Development of Biomedical Engineering in Vietnam which was held from June 16-18, 2014 in Ho Chi Minh City. The volume reflects the progress of Biomedical Engineering and discusses problems and solutions. I aims identifying new challenges, and shaping future directions for research in biomedical engineering fields including medical instrumentation, bioinformatics, biomechanics, medical imaging, drug delivery therapy, regenerative medicine and entrepreneurship in medical devices.

A Compendium of Partial Differential Equation Models

A Compendium of Partial Differential Equation Models Book
Author : William E. Schiesser,Graham W. Griffiths
Publisher : Cambridge University Press
Release : 2009-03-16
ISBN : 0521519861
Language : En, Es, Fr & De

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Book Description :

Presents numerical methods and computer code in Matlab for the solution of ODEs and PDEs with detailed line-by-line discussion.

Vasculopathies

Vasculopathies Book
Author : Marc Thiriet
Publisher : Springer
Release : 2019-02-18
ISBN : 3319893157
Language : En, Es, Fr & De

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Book Description :

This volume presents one of the clinical foundations of vasculopathies: the biological markers and risk factors associated with cardiovascular disease. A detailed biological and clinical framework is provided as a prerequisite for adequate modeling. Chapter 1 presents cardiovascular risk factors and markers, where the search for new criteria is aimed at improving early detection of chronic diseases. The subsequent chapters focus on hypertension, which involves the kidney among other organs as well as many agents, hyperglycemia and diabetes, hyperlipidemias and obesity, and behavior. The last of these risk factors includes altered circadian rhythm, tobacco and alcohol consumption, physical inactivity, and diet. The volumes in this series present all of the data needed at various length scales for a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in anatomical conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning in quantitative terms.

Dynamic Modeling of Transport Process Systems

Dynamic Modeling of Transport Process Systems Book
Author : C. A. Silebi,William E. Schiesser
Publisher : Elsevier
Release : 2012-12-02
ISBN : 0080925820
Language : En, Es, Fr & De

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Book Description :

This book presents a methodology for the development and computer implementation of dynamic models for transport process systems. Rather than developing the general equations of transport phenomena, it develops the equations required specifically for each new example application. These equations are generally of two types: ordinary differential equations (ODEs) and partial differential equations (PDEs) for which time is an independent variable. The computer-based methodology presented is general purpose and can be applied to most applications requiring the numerical integration of initial-value ODEs/PDEs. A set of approximately two hundred applications of ODEs and PDEs developed by the authors are listed in Appendix 8.

The Numerical Method of Lines

The Numerical Method of Lines Book
Author : William E. Schiesser
Publisher : Elsevier
Release : 2012-07-27
ISBN : 0128015519
Language : En, Es, Fr & De

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Book Description :

This is the first book on the numerical method of lines, a relatively new method for solving partial differential equations. The Numerical Method of Lines is also the first book to accommodate all major classes of partial differential equations. This is essentially an applications book for computer scientists. The author will separately offer a disk of FORTRAN 77 programs with 250 specific applications, ranging from "Shuttle Launch Simulation" to "Temperature Control of a Nuclear Fuel Rod."

Bio nanoimaging

Bio nanoimaging Book
Author : Vladimir Uversky,Yuri Lyubchenko
Publisher : Academic Press
Release : 2013-11-05
ISBN : 0123978211
Language : En, Es, Fr & De

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Book Description :

Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering: - Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobulin, studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin oligomers - Polymorphisms of misfolding and aggregation processes, including multiple pathways of lysozyme aggregation, misfolded intermediate of a PDZ domain, and micelle formation by human islet amyloid polypeptide Protein misfolding and aggregation is a fast-growing frontier in molecular medicine and protein chemistry. Related disorders include cataracts, arthritis, cystic fibrosis, late-onset diabetes mellitus, and numerous neurodegenerative diseases like Alzheimer's and Parkinson's. Nanoimaging technology has proved crucial in understanding protein-misfolding pathologies and in potential drug design aimed at the inhibition or reversal of protein aggregation. Using these technologies, researchers can monitor the aggregation process, visualize protein aggregates and analyze their properties. Provides practical examples of nanoimaging research from leading molecular biology, cell biology, protein chemistry, biotechnology, genetics, and pharmaceutical labs Includes over 200 color images to illustrate the power of various nanoimaging technologies Focuses on nanoimaging techniques applied to protein misfolding and aggregation in molecular medicine

Computational Transport Phenomena

Computational Transport Phenomena Book
Author : W. E. Schiesser,C. A. Silebi
Publisher : Cambridge University Press
Release : 1997-08-13
ISBN : 9780521556538
Language : En, Es, Fr & De

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Book Description :

A clear, user-oriented introduction to the subject of computational transport phenomena, first published in 1997.

Numerical and Statistical Methods for Bioengineering

Numerical and Statistical Methods for Bioengineering Book
Author : Michael R. King,Nipa A. Mody
Publisher : Cambridge University Press
Release : 2010-11-04
ISBN : 9780521871587
Language : En, Es, Fr & De

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Book Description :

The first MATLAB-based numerical methods textbook for bioengineers that uniquely integrates modelling concepts with statistical analysis, while maintaining a focus on enabling the user to report the error or uncertainty in their result. Between traditional numerical method topics of linear modelling concepts, nonlinear root finding, and numerical integration, chapters on hypothesis testing, data regression and probability are interweaved. A unique feature of the book is the inclusion of examples from clinical trials and bioinformatics, which are not found in other numerical methods textbooks for engineers. With a wealth of biomedical engineering examples, case studies on topical biomedical research, and the inclusion of end of chapter problems, this is a perfect core text for a one-semester undergraduate course.

Mathematical Modeling Approach To Infectious Diseases A Cross Diffusion Pde Models For Epidemiology

Mathematical Modeling Approach To Infectious Diseases  A  Cross Diffusion Pde Models For Epidemiology Book
Author : Schiesser William E
Publisher : World Scientific
Release : 2018-06-27
ISBN : 9813238801
Language : En, Es, Fr & De

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Book Description :

Download Mathematical Modeling Approach To Infectious Diseases A Cross Diffusion Pde Models For Epidemiology book written by Schiesser William E, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Differential Equation Analysis in Biomedical Science and Engineering

Differential Equation Analysis in Biomedical Science and Engineering Book
Author : William E. Schiesser
Publisher : John Wiley & Sons
Release : 2014-03-31
ISBN : 1118705165
Language : En, Es, Fr & De

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Book Description :

Features a solid foundation of mathematical and computational tools to formulate and solve real-world PDE problems across various fields With a step-by-step approach to solving partial differential equations (PDEs), Differential Equation Analysis in Biomedical Science and Engineering: Partial Differential Equation Applications with R successfully applies computational techniques for solving real-world PDE problems that are found in a variety of fields, including chemistry, physics, biology, and physiology. The book provides readers with the necessary knowledge to reproduce and extend the computed numerical solutions and is a valuable resource for dealing with a broad class of linear and nonlinear partial differential equations. The author’s primary focus is on models expressed as systems of PDEs, which generally result from including spatial effects so that the PDE dependent variables are functions of both space and time, unlike ordinary differential equation (ODE) systems that pertain to time only. As such, the book emphasizes details of the numerical algorithms and how the solutions were computed. Featuring computer-based mathematical models for solving real-world problems in the biological and biomedical sciences and engineering, the book also includes: R routines to facilitate the immediate use of computation for solving differential equation problems without having to first learn the basic concepts of numerical analysis and programming for PDEs Models as systems of PDEs and associated initial and boundary conditions with explanations of the associated chemistry, physics, biology, and physiology Numerical solutions of the presented model equations with a discussion of the important features of the solutions Aspects of general PDE computation through various biomedical science and engineering applications Differential Equation Analysis in Biomedical Science and Engineering: Partial Differential Equation Applications with R is an excellent reference for researchers, scientists, clinicians, medical researchers, engineers, statisticians, epidemiologists, and pharmacokineticists who are interested in both clinical applications and interpretation of experimental data with mathematical models in order to efficiently solve the associated differential equations. The book is also useful as a textbook for graduate-level courses in mathematics, biomedical science and engineering, biology, biophysics, biochemistry, medicine, and engineering.

Ordinary and Partial Differential Equation Routines in C C Fortran Java Maple and MATLAB

Ordinary and Partial Differential Equation Routines in C  C    Fortran  Java  Maple  and MATLAB Book
Author : H.J. Lee,W.E. Schiesser
Publisher : CRC Press
Release : 2003-11-24
ISBN : 0203010515
Language : En, Es, Fr & De

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Book Description :

This book provides a set of ODE/PDE integration routines in the six most widely used computer languages, enabling scientists and engineers to apply ODE/PDE analysis toward solving complex problems. This text concisely reviews integration algorithms, then analyzes the widely used Runge-Kutta method. It first presents a complete code before discussin

Systems Biology and Its Application in TCM Formulas Research

Systems Biology and Its Application in TCM Formulas Research Book
Author : Wei-Dong Zhang
Publisher : Academic Press
Release : 2018-02-16
ISBN : 0128127457
Language : En, Es, Fr & De

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Book Description :

Systems Biology and Its Application in TCM Formulas Research presents a theoretical research system formed for Traditional Chinese Medicine (TCM) formulas, along with information on the study of Shexiang Baoxin Pill (SBP), a TCM formula that has shown significant clinical efficacy in the treatment of cardiovascular diseases. The content combines theory and practice, and includes guidance for both theoretical concepts and operable technical routes. This is a valuable source not only for biomedical researchers involved in Systems Biology studies, but also for students and scientists interested in learning more about Traditional Chinese Medicine and its applications in contemporary medicine. Explains, in detail, the Shexiang Baoxin Pill (SBP), a TCM formula efficiently applied in the treatment of cardiovascular diseases Presents TCM formulas from perspectives of systems biology, basic chemical material groups, modern pharmacology and network biology Offers an overview on biology, modern chemistry and information technology as applied in Systems Biology research

Artificial Neural Networks

Artificial Neural Networks Book
Author : Hugh Cartwright
Publisher : Springer
Release : 2017-04-30
ISBN : 9781493948932
Language : En, Es, Fr & De

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Book Description :

This volume presents examples of how ANNs are applied in biological sciences and related areas. Chapters focus on the analysis of intracellular sorting information, prediction of the behavior of bacterial communities, biometric authentication, studies of Tuberculosis, gene signatures in breast cancer classification, use of mass spectrometry in metabolite identification, visual navigation, and computer diagnosis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Artificial Neural Networks: Second Edition aids scientists in continuing to study Artificial Neural Networks (ANNs).

Mechanical Circulatory and Respiratory Support

Mechanical Circulatory and Respiratory Support Book
Author : Shaun Gregory,Michael Stevens,John F Fraser
Publisher : Academic Press
Release : 2017-09-19
ISBN : 0128104929
Language : En, Es, Fr & De

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Book Description :

Mechanical Circulatory and Respiratory Support is a comprehensive overview of the past, present and future development of mechanical circulatory and respiratory support devices. Content from over 60 internationally-renowned experts focusses on the entire life-cycle of mechanical circulatory and respiratory support – from the descent into heart and lung failure, alternative medical management, device options, device design, implantation techniques, complications and medical management of the supported patient, patient-device interactions, cost effectiveness, route to market and a view to the future. This book is written as a useful resource for biomedical engineers and clinicians who are designing new mechanical circulatory or respiratory support devices, while also providing a comprehensive guide of the entire field for those who are already familiar with some areas and want to learn more. Reviews of the most cutting-edge research are provided throughout each chapter, along with guides on how to design new devices and which areas require specific focus for future research and development. Covers a variety of disciplines, from anatomy of organs and evolution of cardiovascular devices, to their clinical applications and the manufacturing and marketing of devices Provides engineering and clinical perspectives to assist readers in the design of a market appropriate device Discusses history, design, usage, and development of mechanical circulatory and respiratory support systems

Computational Modeling Of The Covid 19 Disease Numerical Ode Analysis With R Programming

Computational Modeling Of The Covid 19 Disease  Numerical Ode Analysis With R Programming Book
Author : William E Schiesser
Publisher : World Scientific
Release : 2020-06-16
ISBN : 9811222894
Language : En, Es, Fr & De

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Book Description :

The book is intended for readers who are interested in learning about the use of computer-based modelling of the COVID-19 disease. It provides a basic introduction to a five-ordinary differential equation (ODE) model by providing a complete statement of the model, including a detailed discussion of the ODEs, initial conditions and parameters, followed by a line-by-line explanation of a set of R routines (R is a quality, scientific programming system readily available from the Internet). The reader can access and execute these routines without having to first study numerical algorithms and computer coding (programming) and can perform numerical experimentation with the model on modest computers.

Immersive Analytics

Immersive Analytics Book
Author : Kim Marriott,Falk Schreiber,Tim Dwyer,Karsten Klein,Nathalie Henry Riche,Takayuki Itoh,Wolfgang Stuerzlinger,Bruce H. Thomas
Publisher : Springer
Release : 2018-10-15
ISBN : 303001388X
Language : En, Es, Fr & De

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Book Description :

Immersive Analytics is a new research initiative that aims to remove barriers between people, their data and the tools they use for analysis and decision making. Here the aims of immersive analytics research are clarified, its opportunities and historical context, as well as providing a broad research agenda for the field. In addition, it is reviewed how the term immersion has been used to refer to both technological and psychological immersion, both of which are central to immersive analytics research.