Numerical Methods And Advanced Simulation In Biomechanics And Biological Processes

Book Description :

Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes covers new and exciting modeling methods to help bioengineers tackle problems for which the Finite Element Method is not appropriate. The book covers a wide range of important subjects in the field of numerical methods applied to biomechanics, including bone biomechanics, tissue and cell mechanics, 3D printing, computer assisted surgery and fluid dynamics. Modeling strategies, technology and approaches are continuously evolving as the knowledge of biological processes increases. Both theory and applications are covered, making this an ideal book for researchers, students and R&D professionals. Provides non-conventional analysis methods for modeling Covers the Discrete Element Method (DEM), Particle Methods (PM), MessLess and MeshFree Methods (MLMF), Agent-Based Methods (ABM), Lattice-Boltzmann Methods (LBM) and Boundary Integral Methods (BIM) Includes contributions from several world renowned experts in their fields Compares pros and cons of each method to help you decide which method is most applicable to solving specific problems

Book Description :

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Book Description :

This book introduces concepts and practical tools for dynamical mathematical modeling of biological systems. Dynamical models describe the behavior of a system over time as a result of internal feedback loops and external forcing, based on mathematically formulated dynamical laws, similarly to how Newton's laws describe the movement of celestial bodies. Dynamical models are increasingly popular in biology, as they tend to be more powerful than static regression models. This book is meant for undergraduate and graduate students in physics, applied mathematics and data science with an interest in biology, as well as students in biology with a strong interest in mathematical methods. The book covers deterministic models (for example differential equations), stochastic models (for example Markov chains and autoregressive models) and model-independent aspects of time series analysis. Plenty of examples and exercises are included, often taken or inspired from the scientific literature, and covering a broad range of topics such as neuroscience, cell biology, genetics, evolution, ecology, microbiology, physiology, epidemiology and conservation. The book delivers generic modeling techniques used across a wide range of situations in biology, and hence readers from other scientific disciplines will find that much of the material is also applicable in their own field. Proofs of most mathematical statements are included for the interested reader, but are not essential for a practical understanding of the material. The book introduces the popular scientific programming language MATLAB as a tool for simulating models, fitting models to data, and visualizing data and model predictions. The material taught is current as of MATLAB version 2022b. The material is taught in a sufficiently general way that also permits the use of alternative programming languages.

Book Description :

The book presents some recent specialized works of a theoretical and practical nature in the field of simulation modeling, which is being addressed to a large number of specialists, mathematicians, doctors, engineers, economists, professors, and students. The book comprises 11 chapters that promote modern mathematical algorithms and simulation modeling techniques, in practical applications, in the following thematic areas: mathematics, biomedicine, systems of systems, materials science and engineering, energy systems, and economics. This project presents scientific papers and applications that emphasize the capabilities of simulation modeling methods, helping readers to understand the phenomena that take place in the real world, the conditions of their development, and their effects, at a high scientific and technical level. The authors have published work examples and case studies that resulted from their researches in the field. The readers get new solutions and answers to questions related to the emerging applications of simulation modeling and their advantages.

Book Description :

Innovations and Emerging Technologies in Wound Care is a pivotal book on the prevention and management of chronic and non-healing wounds. The book clearly presents the research and evidence that should be considered when planning care interventions to improve health related outcomes for patients. New and emerging technologies are discussed and identified, along with tactics on how they can be integrated into clinical practice. This book offers readers a bridge between biomedical engineering and medicine, with an emphasis on technological innovations. It includes contributions from engineers, scientists, clinicians and industry professionals. Users will find this resource to be a complete picture of the latest knowledge on the tolerance of human tissues to sustained mechanical and thermal loads that also provides a deeper understanding of the risk for onset and development of chronic wounds. Describes the state-of-knowledge in wound research, including tissue damage cascades and healing processes Covers all state-of-the-art technology in wound prevention, diagnosis, prognosis and treatment Discusses emerging research directions and future technology trends in the field of wound prevention and care Offers a bench-to-bedside exploration of the key issues that affect the practice of prevention and management of non-healing wounds

Book Description :

This conference book contains papers presented at the 8th GACM Colloquium on Computational Mechanics for Young Scientists from Academia and Industry. The conference was held from August 28th – 30th, 2019 in Kassel, hosted by the Institute of Mechanics and Dynamics of the department for civil and environmental engineering and by the chair of Engineering Mechanics / Continuum Mechanics of the department for mechanical engineering of the University of Kassel. The aim of the conference is, to bring together young scientits who are engaged in academic and industrial research on Computational Mechanics and Computer Methods in Applied Sciences. It provides a plattform to present and discuss recent results from research efforts and industrial applications. In more than 150 presentations, given by young scientists, current scientific developments and advances in engineering practice in this field are presented and discussed. The contributions of the young researchers are supplemented by a poster session and plenary talks from four senior scientists from academia and industry as well as from the GACM Best PhD Award winners 2017 and 2018.

Book Description :

Encyclopedia of Environmental Health, Second Edition presents the newest release in this fundamental reference that updates and broadens the umbrella of environmental health— especially social and environmental health—for its readers. There is ongoing revolution in governance, policies and intervention strategies aimed at evolving changes in health disparities, disease burden, trans-boundary transport and health hazards. This new edition reflects these realities, mapping new directions in the field that include how to minimize threats and develop new scientific paradigms that address emerging local, national and global environmental concerns. Represents a one-stop resource for scientifically reliable information on environmental health Fills a critical gap, with information on one of the most rapidly growing scientific fields of our time Provides comparative approaches to environmental health practice and research in different countries and regions of the world Covers issues behind specific questions and describes the best available scientific methods for environmental risk assessment

Book Description :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSC Technology, Volume 5 addresses the progress in induced pluripotent stem cells (iPSCs) technologies. Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes different technologies and strategies to use iPSCs for biological and clinical benefit. In recent years, remarkable progress has been made in the obtention of iPSCs and their differentiation into several cell types, tissues, and organs using state-of-the-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. This volume will cover hot topics in the iPSC field, such as iPSCs for modeling the cardiovascular toxicities of anticancer therapies, iPSC differentiation through the lens of the noncoding genome, modeling of blood–brain barrier with iPSCs, mathematical modeling of iPSCs, iPSCs to study human brain evolution, selfrenewal in iPSCs, differences and similarities between iPSCs and embryonic stem cells, and more. The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine, and therapeutics. Covers the following topics: iPSCs for modeling the cardiovascular toxicities of anticancer therapies, iPSC differentiation through the lens of the non-coding genome, modeling of blood-brain barrier with iPSCs, mathematical modelling of iPSCs, iPSCs to study human brain evolution, self-renewal in iPSCs, differences and similarities between iPSCs and embryonic stem cells, and more. Contributed by world-renown experts in the field

Book Description :

This book constitutes the proceedings of the 15th International Conference on Parallel Computing Technologies, PaCT 2019, held in Almaty, Kazakhstan, in August 2019. The 24 full papers and 10 short papers presented were carefully reviewed and selected from 72 submissions. The papers are organized in topical sections on Programming Languages and Execution Environments; Methods and Tools for Parallel Solution of Large-Scale Problems; Data Processing; Cellular Automata; and Distributed Algorithms.

Book Description :

Bone tissue engineering aims to develop artificial bone substitutes that partially or totally restore the natural regeneration capability of bone tissue lost under circumstances of injury, significant defects, or diseases such as osteoporosis. In this context, biomaterials are the keystone of the methodology. Biomaterials for bone tissue engineering have evolved from biocompatible materials that mimic the physical and chemical environment of bone tissue to a new generation of materials that actively interacts with the physiological environment, accelerating bone tissue growth. Mathematical modelling and simulation are important tools in the overall methodology. This book presents an overview of the current investigations and recent contributions in the field of bone tissue engineering. It includes several successful examples of multidisciplinary collaboration in this transversal area of research. The book is intended for students, researchers, and professionals of a number of disciplines, such as engineering, mathematics, physics, chemistry, biomedicine, biology, and veterinary. The book is composed of an editorial section and 16 original research papers authored by leading researchers of this discipline from different laboratories across the world

Book Description :

Encyclopedia of Biomedical Engineering is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers. Provides students with a concise description of the technologies at the interface of the biological sciences and engineering Covers all aspects of biomedical engineering, also incorporating perspectives from experts working within the domains of biomedicine, medical engineering, biology, chemistry, physics, electrical engineering, and more Contains reputable, multidisciplinary content from domain experts Presents a ‘one-stop’ resource for access to information written by world-leading scholars in the field

Book Description :

The Mechanics of Hydrogels: Mechanical Properties, Testing, and Applications offers readers a systematic description of the mechanical properties and characterizations of hydrogels. Practical topics such as manufacturing hydrogels with controlled mechanical properties and the mechanical testing of hydrogels are covered at length, as are areas such as inelastic and nonlinear deformation, rheological characterization, fracture and indentation testing, mechanical properties of cellularly responsive hydrogels, and more. Proper instrumentation and modeling techniques for measuring the mechanical properties of hydrogels are also explored. Links the mechanical and biological behaviors and applications of hydrogels Looks at the manufacturing and mechanical testing of hydrogels Discusses the design and use of hydrogels in a wide array of applications

Book Description :

The combination of readily available computing power and progress in numerical techniques has made nonlinear systems - the kind that only a few years ago were ignored as too complex - open to analysis for the first time. Now realistic models of living systems incorporating the nonlinear variation and anisotropic nature of physical properties can be solved numerically on modern computers to give realistically usable results. This has opened up new and exciting possibilities for the fusing of ideas from physiology and engineering in the burgeoning new field that is biomechanics. Computational Biomechanics presents pioneering work focusing on the areas of orthopedic and circulatory mechanics, using experimental results to confirm or improve the relevant mathematical models and parameters. Together with two companion volumes, Biomechanics: Functional Adaptation and Remodeling and the Data Book on Mechanical Properties of Living Cells, Tissues, and Organs, this monograph will prove invaluable to those working in fields ranging from medical science and clinical medicine to biomedical engineering and applied mechanics.

Book Description :

Advances in Biomechanics and Tissue Regeneration covers a wide range of recent development and advances in the fields of biomechanics and tissue regeneration. It includes computational simulation, soft tissues, microfluidics, the cardiovascular system, experimental methods in biomechanics, mechanobiology and tissue regeneration. The state-of-the-art, theories and application are presented, making this book ideal for anyone who is deciding which direction to take their future research in this field. In addition, it is ideal for everyone who is exploring new fields or currently working on an interdisciplinary project in tissue biomechanics. Combines new trends in biomechanical modelling and tissue regeneration Offers a broad scope, covering the entire field of tissue biomechanics Contains perspectives from engineering, medicine and biology, thus giving a holistic view of the field

Book Description :

This book presents the reader with comprehensive insight into various kinds of mathematical modeling and numerical computation for problems arising in several branches of engineering, such as mechanical engineering, computer science engineering, electrical engineering, electronics and communication engineering, and civil engineering. The book: • Discusses topics related to clean and green energy production and storage • Bridges the gap between core theory and costly industrial experiments • Covers advanced biomechanics and nanodrug delivery topics • Explores diversified applications of mathematical techniques to solve practical engineering problems The text in this book emphasizes mathematical treatment of soft computing, image and signal processing, fluid flows in various geometries, biomechanics, biological modeling, a mathematical description of the solar cell, analytical and numerical treatment of problems in fracture mechanics, and antenna design modeling. It also discusses the numerical computations of biomechanics problems and problems arising in cryptography. The text further covers optimization techniques that are useful for real-world problems. This material is primarily written for graduate students and academic researchers in a number of engineering fields, including electrical, electronics and communication, industrial, manufacturing, mechanical, computer science, and mathematics.

Book Description :

This book communicates the latest findings in pediatric orthopedics and answers key everyday questions in the field in an informative, readily understandable manner. The scope is comprehensive, encompassing all aspects of diagnosis and therapy. After an opening section on basic principles, the two main sections discuss diseases and injuries by site and cover systemic conditions including trauma, infections, juvenile rheumatoid arthritis, tumors and hereditary diseases. The book is the translation of the latest edition of the well-known classic Kinderorthopädie in der Praxis, which presents the collected knowledge of experts from Basel University Children's Hospital – Fritz Hefti and his co-workers Reinald Brunner, Carol Claudius Hasler, and Gernot Jundt. This edition has been revised and updated in a variety of ways. New findings are incorporated into all chapters, important advances in treatment are presented and the latest concepts in tumor diagnosis and neuro-orthopedics are discussed. The book contains more than 150 additional illustrations, including new clinical images and radiographs and many further amusing cartoons by Franz Freuler. The aim is to make children’s orthopedics fun – in both practice and theory! The book has received several awards.

Book Description :

Biological engineering is a field of engineering in which the emphasis is on life and life-sustaining systems. Biological engineering is an emerging discipline that encompasses engineering theory and practice connected to and derived from the science of biology. The most important trend in biological engineering is the dynamic range of scales at which biotechnology is now able to integrate with biological processes. An explosion in micro/nanoscale technology is allowing the manufacture of nanoparticles for drug delivery into cells, miniaturized implantable microsensors for medical diagnostics, and micro-engineered robots for on-board tissue repairs. This book aims to provide an updated overview of the recent developments in biological engineering from diverse aspects and various applications in clinical and experimental research.

Book Description :

Since dentistry is a branch of medicine with its own peculiarities and very diverse areas of action, it can be considered as an interdisciplinary field. BIODENTAL ENGINEERING IV contains the full papers presented at the 4th International Conference on Biodental Engineering (BIODENTAL 2016, Vila Nova de Famalicão, Portugal, 21—23 June 2016), and covers the use of new techniques and technologies in dentistry. The contributions provide a comprehensive coverage of the state-of-the art in this area, and addresses the following topics: • Aesthetics • Bioengineering • Biomaterials • Biomechanical disorders • Biomedical devices • Computational bio- imaging and visualization • Computational methods • Dental medicine • Experimental mechanics • Signal processing and analysis • Implantology • Minimally invasive devices and techniques • Orthodontics • Prosthesis and orthosis • Simulation • Software development • Telemedicine • Tissue engineering • Virtual reality BIODENTAL ENGINEERING IV will be of interest to academics and professionals involved or interested in dentistry, biomechanical disorders, numerical simulation, orthodontics, implantology, aesthetics, dental medicine, medical devices and medical imaging.

Book Description :

This monograph considers the mathematical modeling of cellular adhesion, a key interaction force in cell biology. While deeply grounded in the biological application of cell adhesion and tissue formation, this monograph focuses on the mathematical analysis of non-local adhesion models. The novel aspect is the non-local term (an integral operator), which accounts for forces generated by long ranged cell interactions. The analysis of non-local models has started only recently, and it has become a vibrant area of applied mathematics. This monograph contributes a systematic analysis of steady states and their bifurcation structure, combining global bifurcation results pioneered by Rabinowitz, equivariant bifurcation theory, and the symmetries of the non-local term. These methods allow readers to analyze and understand cell adhesion on a deep level.

Book Description :

The book is devoted to the 70th birthday of Prof. Sergey M. Aizikovich, which will celebrated on August 2nd 2021. His scientific interests are related to the following topics: Mechanics of contact interactions, Functionally graded materials, Mechanics of fracture, Integral equations of mathematical physics, Inverse problems of the theory of elasticity, and Applications of elasticity to biological and medical problems of mechanics of materials. The papers, collected in the book, are contributions of authors from 10 countries.