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Nuclear Architecture And Dynamics

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Nuclear Architecture and Dynamics

Nuclear Architecture and Dynamics Book
Author : Christophe Lavelle,Jean-Marc Victor
Publisher : Academic Press
Release : 2017-10-27
ISBN : 012803503X
Language : En, Es, Fr & De

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Book Description :

Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines. Highlights the link between the (bio)chemistry and the (bio)physics of chromatin Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds

Nuclear Architecture and Dynamics

Nuclear Architecture and Dynamics Book
Author : Christophe Lavelle,Jean-Marc Victor
Publisher : Academic Press
Release : 2017-10-01
ISBN : 9780128034804
Language : En, Es, Fr & De

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Book Description :

Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists, molecular and cellular biologists whose research involves a deep understanding of the organization of the genome and the mechanisms that pertain its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. A group of international experts, including biologists, physicists, mathematicians, and bioinformaticians have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field and their relevance to nuclear function and physiological processes. Nuclear Architecture and Dynamics provides the uninitiated with an entry point to a highly dynamic but complex issue and the expert with an opportunity to have a fresh look at the viewpoints advocated by the researchers from the different disciplines that have contributed. Highlights the link between the (bio)chemistry and the (bio)physics of chromatin Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds

Nuclear Dynamics

Nuclear Dynamics Book
Author : K. Nagata,K. Takeyasu
Publisher : Springer Science & Business Media
Release : 2007-12-03
ISBN : 4431301305
Language : En, Es, Fr & De

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Book Description :

The dynamics of nuclear structures described in this book furnish the basis for a comprehensive understanding of how the higher-order organization and function of the nucleus is established and how it correlates with the expression of a variety of vital activities such as cell proliferation and differentiation. The resulting volume creates an invaluable source of reference for researchers in the field.

Nuclear Architecture and Dynamics of Stably Integrated Retroviral Sequences

Nuclear Architecture and Dynamics of Stably Integrated Retroviral Sequences Book
Author : Jens Nagel
Publisher : Unknown
Release : 2011
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Nuclear Architecture and Dynamics of Stably Integrated Retroviral Sequences book written by Jens Nagel, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nuclear Architecture and Structural Dynamics

Nuclear Architecture and Structural Dynamics Book
Author : Josef H. Exler
Publisher : Unknown
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Nuclear Architecture and Structural Dynamics book written by Josef H. Exler, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nuclear Envelope Dynamics in Embryos and Somatic Cells

Nuclear Envelope Dynamics in Embryos and Somatic Cells Book
Author : Philippe Collas
Publisher : Springer
Release : 2012-11-01
ISBN : 9781461349372
Language : En, Es, Fr & De

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Book Description :

This volume provides an exhaustive review of the most current knowledge of the composition, architecture and dynamics of the nuclear envelope. In contrast to other comprehensive works on cellular membranes in general, this book is the first to specifically address the nuclear envelope. Experts in the field relate the different domains of the nuclear envelope, their biogenesis, their composition, their mode of targeting to chromosomes and how they dissociate from chromosomes upon cell division. A wealth of information from several experimental systems is provided, such as dividing somatic cells, embryos and nuclear assembly assays in cell-free extracts, in a wide range of vertebrate and invertebrate organisms ranging from humans to yeast. The book also contains up-to-date reviews on the relationship between mutations in proteins of the nuclear envelope and Emery-Dreifuss muscular dystrophy. The breadth of topics covered in what may seem to be a field as narrow as the nuclear envelope makes this volume a valuable reference.

Annual Plant Reviews Plant Nuclear Structure Genome Architecture and Gene Regulation

Annual Plant Reviews  Plant Nuclear Structure  Genome Architecture and Gene Regulation Book
Author : David Evans,Katja Graumann,John A. Bryant
Publisher : John Wiley & Sons
Release : 2013-03-27
ISBN : 1118472489
Language : En, Es, Fr & De

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Book Description :

This timely volume brings together expert reviews of the recentsignificant advances in our knowledge and understanding of theorganisation of the higher plant nucleus, and in particular in therelationship between nuclear organisation and the regulation ofgene expression. Rapid progress has been made in a number of keyareas over the last five years, including description andcharacterization of proteins of the nuclear envelope and nuclearpore complex, novel insights into nucleoskeletal structures, aswell as developments related to chromatin organization, functionand gene expression. These advances open the way for new researchinto areas such as stress tolerance, plant-pathogen interactionsand ultimately crop improvement and food security. Continuedresearch into plant nuclear structure, genome architecture and generegulation also enriches our understanding of the origin andevolution of the nucleus and its envelope. Edited by world-class researchers in plant cell biology, andcomprising contributions from internationally-renowned academics,this latest volume in the prestigious Annual Plant Reviews seriesbrings together a wealth of knowledge in the burgeoning field ofplant nuclear structure and genetics. Annual Plant Reviews, Volume 46: Plant Nuclear Structure,Genome Architecture and Gene Regulation is a vitalresource for advanced students, researchers and professionals inplant science and related disciplines. Libraries in all researchestablishments where plant science, biochemistry, molecularbiology, genetics and genomics and agricultural science are taughtand studied will find this excellent volume an essential additionto their shelf.

Advances in Nuclear Architecture

Advances in Nuclear Architecture Book
Author : Niall M. Adams,Paul S. Freemont
Publisher : Springer Science & Business Media
Release : 2010-10-17
ISBN : 9048198992
Language : En, Es, Fr & De

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Book Description :

This book provides a snapshot of the state-of-the art in the study of mammalian cell nuclear architecture, and features a diverse range of chapters written by top researchers. A key aspect is an emphasis on precise and repeatable quantitative analysis and simulation in addition to the more familiar biological perspective. The fusion of such material frames the future of the discipline. Quantitative contributions stress reproducible and robust 3D analysis, using a variety of tools ranging from point pattern analysis to shape registration methods. Biological insights include the role of nuclear subdomains in cancer, nuclear molecular motors, and a holistic view of gene transcription.

Nuclear Chromosomal and Genomic Architecture in Biology and Medicine

Nuclear  Chromosomal  and Genomic Architecture in Biology and Medicine Book
Author : Malgorzata Kloc,Jacek Z. Kubiak
Publisher : Springer Nature
Release : 2022-11-08
ISBN : 3031065735
Language : En, Es, Fr & De

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Book Description :

This volume reviews the latest research on the functional implications of nuclear, chromosomal and genomic organization and architecture on cell and organismal biology, and development and progression of diseases. The architecture of the cell nucleus and non-random arrangement of chromosomes, genes, and the non-membranous nuclear bodies in the three-dimensional (3D) space alters in response to the environmental, mechanical, chemical, and temporal cues. The changes in the nuclear, chromosomal, or genomic compaction and configuration modify the gene expression program and induce or inhibit epigenetic modifications. The intrinsically programmed rearrangements of the nuclear architecture are necessary for cell differentiation, the establishment of cell fate during development and maturation of tissues and organs including the immune, muscle, and nervous systems. The non-programmed changes in the nuclear architecture can lead to fragmentation of the nucleus and instability of the genome and thus cause cancer. Microbial and viral infections can lead to a clustering of centromeres, telomeres and ribosomal DNA and alter the properties of the nuclear membrane, allowing large immobile macromolecules to enter the nucleus. Recent advances in next-generation sequencing technologies combined with nucleus/chromosome conformation capture, super-resolution imaging, chromosomal contact maps methods, integrative modeling, and genetic approaches, are uncovering novel features and importance of nuclear, chromosomal and genomic architecture. This book is an interesting read for cell biologists, researchers studying the structure and function of chromosomes, and anyone else who wants to get an overview of the field of nuclear, chromosomal and genomic architecture.

Genome Organization And Function In The Cell Nucleus

Genome Organization And Function In The Cell Nucleus Book
Author : Karsten Rippe
Publisher : John Wiley & Sons
Release : 2012-01-09
ISBN : 3527640002
Language : En, Es, Fr & De

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Book Description :

By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gained knowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair, recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions and non-coding RNAs, chromatin structure, epigenetics and nuclear organization. With its focus on fundamental mechanisms and the associated biomolecules, this will remain essential reading for years to come.

Chromatin Regulation and Dynamics

Chromatin Regulation and Dynamics Book
Author : Anita Göndör
Publisher : Academic Press
Release : 2016-06-01
ISBN : 9780128033951
Language : En, Es, Fr & De

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Book Description :

Chromatin Regulation and Dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The final chapters discuss the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin Regulation and Dynamics, part of the Translational Epigenetics series, facilitates the flow of information between research areas such as chromatin regulation, developmental biology, and epidemiology by focusing on recent findings of the fast-moving field of chromatin regulation. Presents and discusses novel principles of chromatin regulation and dynamics with a cross-disciplinary perspective Promotes crosstalk between basic sciences and their applications in medicine Provides a framework for future studies on complex diseases by integrating various aspects of chromatin biology with cellular metabolic states, with an emphasis on the dynamic nature of chromatin and stochastic principles Integrates knowledge on the dynamic regulation of primary chromatin fiber with 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes

Chromosome Structures Advances in Research and Application 2012 Edition

Chromosome Structures   Advances in Research and Application  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-26
ISBN : 1464991979
Language : En, Es, Fr & De

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Book Description :

Chromosome Structures—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Chromosome Structures. The editors have built Chromosome Structures—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chromosome Structures in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Chromosome Structures—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

New Models of the Cell Nucleus Crowding Entropic Forces Phase Separation and Fractals

New Models of the Cell Nucleus  Crowding  Entropic Forces  Phase Separation  and Fractals Book
Author : Ronald Hancock,Kwang W. Jeon
Publisher : Academic Press
Release : 2013-12-27
ISBN : 0128002522
Language : En, Es, Fr & De

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Book Description :

International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2012: 4.973. Ideas from the fields of biophysics, physical chemistry, of polymer and colloid, and soft matter science have helped clarify the structure and functions of the cell nucleus. The development of powerful methods for modeling conformations and interactions of macromolecules has also contributed. The book aims to encourage cell and molecular biologists to become more familiar with and understand these new concepts and methods, and the crucial contributions they are making to our perception of the nucleus. This is the first volume to present a comprehensive review of New Models of the Cell Nucleus

Multiscale Modeling From Macromolecules to Cell Opportunities and Challenges of Biomolecular Simulations

Multiscale Modeling From Macromolecules to Cell  Opportunities and Challenges of Biomolecular Simulations Book
Author : Valentina Tozzini,Giulia Palermo,Matteo Dal Peraro,Alexandre M. J. J. Bonvin,Rommie E. Amaro
Publisher : Frontiers Media SA
Release : 2020-10-27
ISBN : 2889661091
Language : En, Es, Fr & De

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Book Description :

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Spin Dynamics

Spin Dynamics Book
Author : Malcolm H. Levitt
Publisher : Wiley
Release : 2008-07-31
ISBN : 0470517123
Language : En, Es, Fr & De

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Book Description :

Spin Dynamics: Basics of Nuclear Magnetic Resonance, Second Edition is a comprehensive and modern introduction which focuses on those essential principles and concepts needed for a thorough understanding of the subject, rather than the practical aspects. The quantum theory of nuclear magnets is presented within a strong physical framework, supported by figures. The book assumes only a basic knowledge of complex numbers and matrices, and provides the reader with numerous worked examples and exercises to encourage understanding. With the explicit aim of carefully developing the subject from the beginning, the text starts with coverage of quarks and nucleons and progresses through to a detailed explanation of several important NMR experiments, including NMR imaging, COSY, NOESY and TROSY. Completely revised and updated, the Second Edition features new material on the properties and distributions of isotopes, chemical shift anisotropy and quadrupolar interactions, Pake patterns, spin echoes, slice selection in NMR imaging, and a complete new chapter on the NMR spectroscopy of quadrupolar nuclei. New appendices have been included on Euler angles, and coherence selection by field gradients. As in the first edition, all material is heavily supported by graphics, much of which is new to this edition. Written for undergraduates and postgraduate students taking a first course in NMR spectroscopy and for those needing an up-to-date account of the subject, this multi-disciplinary book will appeal to chemical, physical, material, life, medical, earth and environmental scientists. The detailed physical insights will also make the book of interest for experienced spectroscopists and NMR researchers. • An accessible and carefully written introduction, designed to help students to fully understand this complex and dynamic subject • Takes a multi-disciplinary approach, focusing on basic principles and concepts rather than the more practical aspects • Presents a strong pedagogical approach throughout, with emphasis placed on individual spins to aid understanding • Includes numerous worked examples, problems, further reading and additional notes Praise from the reviews of the First Edition: "This is an excellent book... that many teachers of NMR spectroscopy will cherish... It deserves to be a ‘classic’ among NMR spectroscopy texts." NMR IN BIOMEDICINE "I strongly recommend this book to everyone…it is probably the best modern comprehensive description of the subject." ANGEWANDTE CHEMIE, INTERNATIONAL EDITION

Chromatin Spatial Configuration and Function in Metazoans

Chromatin Spatial Configuration and Function in Metazoans Book
Author : Mayra Furlan-Magaril,Katarzyna Oktaba,Paul Delgado-Olguin
Publisher : Frontiers Media SA
Release : 2021-09-30
ISBN : 2889714314
Language : En, Es, Fr & De

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Book Description :

Download Chromatin Spatial Configuration and Function in Metazoans book written by Mayra Furlan-Magaril,Katarzyna Oktaba,Paul Delgado-Olguin, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cells

Cells Book
Author : Vishwanath R. Lingappa,George Plopper
Publisher : Jones & Bartlett Learning
Release : 2007
ISBN : 9780763739058
Language : En, Es, Fr & De

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Book Description :

"CELLS, the most cutting-edge textbook in the field, is the ideal resource for advanced undergraduate and graduate students entering the world of cell biology, and is a useful tool for scientists who wish to learn more about topics outside their field. This important new text provides full coverage of the structure, organization, growth, regulation, movements, and interaction of cells, with an emphasis on eukaryotic cells. Where they are known, the molecular bases for human diseases are discussed in each chapter.Under the direction of Dr. Benjamin Lewin and three expert lead editors, each chapter was prepared by top scientists who specialize in the subject area. All chapters were carefully edited to maintain consistent use of terminology and to achieve a homogeneous level of detail and rigor."--Publisher's website.

Nuclear Mechanics and Genome Regulation

Nuclear Mechanics and Genome Regulation Book
Author : Anonim
Publisher : Academic Press
Release : 2010-10-12
ISBN : 9780123810106
Language : En, Es, Fr & De

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Book Description :

In recent years new discoveries have made this an exciting and important field of research. This exhaustive volume presents comprehensive chapters and detailed background information for researchers working with in the field of nuclear mechanics and genome regulation. Both classic and state-of-the-art methods readily adaptable and designed to last the test of time Relevant to clinicians and scientists working in a wide range of fields

Modeling the 3D Conformation of Genomes

Modeling the 3D Conformation of Genomes Book
Author : Guido Tiana,Luca Giorgetti
Publisher : CRC Press
Release : 2019-01-15
ISBN : 1351387006
Language : En, Es, Fr & De

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Book Description :

This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the cell nucleus. Chapters explain how to convert raw experimental data into 3D conformations, and how to use models to better understand biophysical mechanisms that control chromosome conformation. The coverage ranges from introductory chapters to modeling aspects related to polymer physics, and data-driven models for genomic domains, the entire human genome, epigenome folding, chromosome structure and dynamics, and predicting 3D genome structure.