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Nonhuman Primates In Biomedical Research

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Nonhuman Primates in Biomedical Research

Nonhuman Primates in Biomedical Research Book
Author : Christian R. Abee,Keith Mansfield,Suzette D. Tardif,Timothy Morris
Publisher : Academic Press
Release : 2012-06-07
ISBN : 0123978386
Language : En, Es, Fr & De

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Book Description :

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information Includes four color images throughout

Nonhuman Primates in Biomedical Research

Nonhuman Primates in Biomedical Research Book
Author : Christian R. Abee,Keith Mansfield,Suzette D. Tardif,Timothy Morris
Publisher : Academic Press
Release : 2012-03-29
ISBN : 0123813662
Language : En, Es, Fr & De

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Book Description :

Annotation A comprehensive review of the use of nonhuman primates in biomedical research. This volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases.

Nonhuman Primates in Biomedical Research

Nonhuman Primates in Biomedical Research Book
Author : Anonim
Publisher : Academic Press
Release : 1995-08-04
ISBN : 0080537642
Language : En, Es, Fr & De

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Book Description :

This book represents the most comprehensive publication of its type on nonhuman primates. It also provides basic information on the biology and management of primates for anyone responsible for the care and use of these animals. A related book on primate diseases will be published in 1996. Stresses the following major topics: Biology and medical management Reproductive physiology and breeding Nutrition Biohazards

Nonhuman Primates in Biomedical Research

Nonhuman Primates in Biomedical Research Book
Author : Christian R. Abee,Keith Mansfield,Suzette D. Tardif,Timothy Morris
Publisher : Academic Press
Release : 2012-05-09
ISBN : 0123978378
Language : En, Es, Fr & De

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Book Description :

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Now in four color throughout, making the book more visually stimulating to enhance learning and ease of use Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information

Occupational Health and Safety in the Care and Use of Nonhuman Primates

Occupational Health and Safety in the Care and Use of Nonhuman Primates Book
Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee on Occupational Health and Safety in the Care and Use of Nonhuman Primates
Publisher : National Academies Press
Release : 2003-07-13
ISBN : 030908914X
Language : En, Es, Fr & De

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Book Description :

The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.

The Psychological Well Being of Nonhuman Primates

The Psychological Well Being of Nonhuman Primates Book
Author : National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Well-Being of Nonhuman Primates
Publisher : National Academies Press
Release : 1998-11-03
ISBN : 0309176506
Language : En, Es, Fr & De

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Book Description :

A 1985 amendment to the Animal Welfare Act requires those who keep nonhuman primates to develop and follow appropriate plans for promoting the animals' psychological well-being. The amendment, however, provides few specifics. The Psychological Well-Being of Nonhuman Primates recommends practical approaches to meeting those requirements. It focuses on what is known about the psychological needs of primates and makes suggestions for assessing and promoting their well-being. This volume examines the elements of an effective care program--social companionship, opportunities for species-typical activity, housing and sanitation, and daily care routines--and provides a helpful checklist for designing a plan for promoting psychological well-being. The book provides a wealth of specific and useful information about the psychological attributes and needs of the most widely used and exhibited nonhuman primates. Readable and well-organized, it will be welcomed by animal care and use committees, facilities administrators, enforcement inspectors, animal advocates, researchers, veterinarians, and caretakers.

The Laboratory Nonhuman Primate

The Laboratory Nonhuman Primate Book
Author : Jeffrey D. Fortman,Terry A. Hewett,Lisa Halliday
Publisher : CRC Press
Release : 2018
ISBN : 9781138106949
Language : En, Es, Fr & De

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Book Description :

The Laboratory Nonhuman Primate, Second Edition continues the second generation of books in the successful, well-received The Laboratory Animal Pocket Reference Series. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the laboratory setting. It serves as a reference for experienced individuals in the field, as well as students. This newest edition is printed in full color to provide greater clarity to the techniques and concepts discussed. Technical procedures and management practices are illustrated with figures and tables, in a clear, easy-to-read format.

Pocket Handbook of Nonhuman Primate Clinical Medicine

Pocket Handbook of Nonhuman Primate Clinical Medicine Book
Author : Angela Courtney
Publisher : CRC Press
Release : 2012-10-18
ISBN : 1439867283
Language : En, Es, Fr & De

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Book Description :

Sources of clinical treatment information on nonhuman primates are generally scattered across journals, textbooks, conferences, personal conversations, and more. However, when a clinician on the treatment floor is faced with a patient requiring an immediate treatment decision, time spent on making an informed decision becomes a critical factor. An alternative to conducting a literature search in time-sensitive situations, the Pocket Handbook of Nonhuman Primate Clinical Medicine supplies guidance and initial direction on diagnosis and treatment, including working doses based on past case experience. It is the frank, to-the-point nature of the writing that makes readers feel as if they had just asked a colleague how to approach a clinical problem and obtained a quick, "what you need to know" answer. The chapter authors draw on personal experience to describe commonly encountered clinical conditions and how to treat these cases—including not only the "dos" but also the "don’ts." This format gives readers easy access to clinical signs, diagnostic criteria, and options for treatment. The Pocket Handbook of Nonhuman Primate Clinical Medicine is a convenient, concise, case-based handbook written by and for clinicians in charge of the diagnosis and treatment of nonhuman primate patients. Available in both print and electronic formats, this handbook saves readers from having to wade through pages of data and case studies to find answers when time is a factor on the clinic floor.

Ethics Dumping

Ethics Dumping Book
Author : Doris Schroeder,Julie Cook,François Hirsch
Publisher : Unknown
Release : 2020-10-08
ISBN : 9781013269400
Language : En, Es, Fr & De

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Book Description :

This book provides original, up-to-date case studies of "ethics dumping" that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the forementioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Laboratory Primate Handbook

Laboratory Primate Handbook Book
Author : Robert Arthur Whitney,Donald J. Johnson,William C. Cole
Publisher : Unknown
Release : 1973
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Laboratory Primate Handbook book written by Robert Arthur Whitney,Donald J. Johnson,William C. Cole, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nonhuman Primate Models in Preclinical Research

Nonhuman Primate Models in Preclinical Research Book
Author : Huifang Chen
Publisher : Unknown
Release : 2021
ISBN : 9781536199147
Language : En, Es, Fr & De

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Book Description :

"Due to the phylogenetic relationship and close genetic and biological similarities with humans, non-human primates (NHP) are regularly used in biomedical and behavioural research. However, because of their highly developed cognitive abilities and social skills, the use of these animals in biomedical research is debated more and more. Although it is acknowledged that in specific research areas NHP are still essential, it is recognized that the use of these animals can only be done under strict conditions under the most optimal welfare aspects. Welfare aspects include housing conditions, non-invasive methods and application of the 3Rs policy. Although many refinement methods have been described in nationally and internationally accepted guidelines on animal laboratory practice, recognition of the guidelines is unfortunately not universal. The present book covers a wide range of NHP models in preclinical research and welfare issues. The following chapters will cover: refinement of the use of NHP in biomedical research; NHP ethics and regulations in Europe; biological basis differences in the human and NHP; the major histocompatibility complex (MHC) immunology in NHP; stem cell biology in NHP; neuro and gliogenesis in an NHP ischemia stroke model; NHP models in autoimmune disease, organ transplantation and infectious disease research; viral diseases in NHP; NHP models in Parkinson's disease, in neurodegenerative disorders research and in cardio-cerebrovascular disease research; islet transplantation; ophthalmic diseases research and neurophysiology in NHP; transgenic engineering in NHP; NHP models of cancers; NHP models in respiratory disease research; NHP models in clinical and non-clinical pharmacology; NHP models in lung transplantation; and aging research in NHP. This book encapsulates a large volume of knowledge scientists have achieved in the field of nonhuman primate models in preclinical research. The editors have invited experts from the United States, Canada, and Europe to contribute 23 chapters in their respective fields of their expertise"--

Essentials of Laboratory Animal Science Principles and Practices

Essentials of Laboratory Animal Science  Principles and Practices Book
Author : P. Nagarajan,Ramachandra Gudde,Ramesh Srinivasan
Publisher : Springer Nature
Release : 2021-07-23
ISBN : 981160987X
Language : En, Es, Fr & De

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Book Description :

This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.

Care Use and Welfare of Marmosets as Animal Models for Gene Editing Based Biomedical Research

Care  Use  and Welfare of Marmosets as Animal Models for Gene Editing Based Biomedical Research Book
Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use
Publisher : National Academies Press
Release : 2019-08-26
ISBN : 0309488516
Language : En, Es, Fr & De

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Book Description :

The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.

Nonhuman Primates in Biomedical Research Two Volume Set

Nonhuman Primates in Biomedical Research Two Volume Set Book
Author : Christian R. Abee,Keith Mansfield,Suzette D. Tardif,Timothy Morris
Publisher : Academic Press
Release : 2012-12-31
ISBN : 0124159729
Language : En, Es, Fr & De

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Book Description :

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The publication emphasizes the biology and management, diseases, and biomedical models for nonhuman primate species most commonly used in research. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Now in four color throughout, making the book more visually stimulating to enhance learning and ease of use Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information

Use of Laboratory Animals in Biomedical and Behavioral Research

Use of Laboratory Animals in Biomedical and Behavioral Research Book
Author : National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research
Publisher : National Academies Press
Release : 1988-02-01
ISBN : 0309038391
Language : En, Es, Fr & De

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Book Description :

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Nonhuman Primate Welfare

Nonhuman Primate Welfare Book
Author : Lauren M. Robinson,Alexander Weiss
Publisher : Springer
Release : 2022-04-22
ISBN : 9783030827076
Language : En, Es, Fr & De

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Book Description :

This volume reviews the broad topic of welfare in nonhuman primates under human care. Chapters detail the history of primates in captivity, ethical and legal issues surrounding the use of nonhuman primates as entertainment or in research, the different approaches that welfare are measured, and how housing, enrichment, and other conditions can foster or degrade welfare. Since humans began keeping nonhuman primates we have made vast strides in understanding their cognitive abilities, strong social bonds, vibrant personalities, and their capacity for joy and suffering. With an increasing number of countries banning the use of great apes in biomedical research, the welfare of primates in zoos and research facilities has gained increasing attention. This interdisciplinary work features contributors from many of the fields involved and those on both sides of the issue, thus providing an exhaustive overview of primate welfare. Readers from animal welfare science, primatology, animal testing, veterinary medicine, conservation to ethics and legislation will find this an important account.

Chimpanzees in Biomedical and Behavioral Research

Chimpanzees in Biomedical and Behavioral Research Book
Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research
Publisher : National Academies Press
Release : 2012-01-05
ISBN : 0309220394
Language : En, Es, Fr & De

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Book Description :

For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.

Chimpanzees in Research

Chimpanzees in Research Book
Author : National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Long-Term Care of Chimpanzees
Publisher : National Academies Press
Release : 1997-08-18
ISBN : 9780309184762
Language : En, Es, Fr & De

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Book Description :

Chimpanzees in biomedical and behavioral research constitute a national resource that has been valuable in addressing national health needs. Facilities that house chimpanzees owned and supported by the National Institutes of Health (NIH) have successfully met the research requirements of the scientific community. The captive chimpanzee population in the United States has grown substantially, particularly over the last decade. That growth is due primarily to the success of the NIH-sponsored Chimpanzee Breeding and Research Program, which achieved the birth numbers thought necessary to meet the projected needs of biomedical research. However, the expected level of use of the chimpanzee model in biomedical research did not materialize, and that has created a complex problem that threatens both the availability of chimpanzees for research in the future and the infrastructure required to ensure the well-being of captive chimpanzees used in biomedical research. Because the present system is fragmented, it is impossible to formulate an accurate overview of the size and nature of the chimpanzee population. But, if the chimpanzee is to continue to be used in biomedical research responsibly, effectively, and cost-effectively, we must be able to oversee, track, and coordinate the maintenance and use of chimpanzees and to control the size of the population. To assess the long-range situation and to develop, implement, and monitor the application of policies for the proper use and care of chimpanzees, an authoritative, centralized oversight structure is imperative. Once it is in place, it will be possible to refine and implement this report's recommendations.

Personality and Temperament in Nonhuman Primates

Personality and Temperament in Nonhuman Primates Book
Author : Alexander Weiss,James E. King,Lindsay Murray
Publisher : Springer Science & Business Media
Release : 2011-08-10
ISBN : 9781461401766
Language : En, Es, Fr & De

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Book Description :

Recently, there has been an increased interest in research on personality, temperament, and behavioral syndromes (henceforth to be referred to as personality) in nonhuman primates and other animals. This follows, in part, from a general interest in the subject matter and the realization that individual differences, once consigned to ‘error’ terms in statistical analyses, are potentially important predictors, moderators, and mediators of a wide variety of outcomes ranging from the results of experiments to health to enrichment programs. Unfortunately, while there is a burgeoning interest in the subject matter, findings have been reported in a diverse number of journals and most of the methodological and statistical approaches were developed in research on human personality. The proposed volume seeks to gather submissions from a variety of specialists in research on individual differences in primate temperament, personality, or behavioral syndromes. We anticipate that chapters will cover several areas. The first part of this edited volume will focus on methodological considerations including the advantages and disadvantages of different means of assessing these constructs in primates and introduce some statistical approaches that have typically been the domain of human personality research. Another part of this edited volume will focus on present findings including the physiological and genetic bases of personality dimensions in primates; the relationship between personality and age; how personality may moderate or impact various outcomes including behavior, health, and well-being in captive and non-captive environments. For the third part of the volume we hope to obtain summaries of the existing work of the authors on the evolutionary important of personality dimensions and guideposts for future directions in this new and exciting area of research.

The Common Marmoset in Captivity and Biomedical Research

The Common Marmoset in Captivity and Biomedical Research Book
Author : Robert P. Marini,Lynn M. Wachtman,Suzette D. Tardif,Keith Mansfield,James G. Fox
Publisher : Academic Press
Release : 2018-11-19
ISBN : 012811830X
Language : En, Es, Fr & De

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Book Description :

The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the American College of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset (Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such as macaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. The marmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primate model to study a number of poorly understood disorders, like autism. Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications Includes contributions from renowned and international authors and editors Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series