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NMR Metabolomics in Cancer Research

NMR Metabolomics in Cancer Research Book
Author : Miroslava Čuperlović-Culf
Publisher : Elsevier
Release : 2012-12-17
ISBN : 1908818263
Language : En, Es, Fr & De

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Book Description :

The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field. Focused description of NMR spectroscopy needed by cancer biologists who are starting to use metabolomics Current overview of knowledge related to the cancer metabolic phenotype from the perspective of metabolomics applications Information about the best practices in NMR metabolomics experimentation and data preprocessing as applied to different sample types

Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2007-03
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Metabolomics for Biomedical Research

Metabolomics for Biomedical Research Book
Author : Jerzy Adamski
Publisher : Academic Press
Release : 2020-04
ISBN : 0128127848
Language : En, Es, Fr & De

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Book Description :

Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research. Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects. The book discusses topics such as biomarkers and their requirements to be used in medical research, with the parameters and approaches on how to validate their quality; and animal models and other approaches, as stem cells and organoid culture. Additionally, it explains how metabolomics may be applied in prediction of individual response to drug or disease progression. This book is a valuable source for researchers on systems biology and other members of biomedical field interested in metabolism-oriented studies for medical research.

An Omics Perspective on Cancer Research

An Omics Perspective on Cancer Research Book
Author : William C.S. Cho
Publisher : Springer Science & Business Media
Release : 2010-04-07
ISBN : 9789048126750
Language : En, Es, Fr & De

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Book Description :

Omics is an emerging and exciting area in the field of science and medicine. Numerous promising developments have been elucidated using omics (including genomics, transcriptomics, epigenomics, proteomics, metabolomics, interactomics, cytomics and bioinformatics) in cancer research. The development of high-throughput technologies that permit the solution of deciphering cancer from higher dimensionality will provide a knowledge base which changes the face of cancer understanding and therapeutics. This is the first book to provide such a comprehensive coverage of a rapidly evolving area written by leading experts in the field of omics. It complies and details cutting-edge cancer research that covers the broad advances in the field and its application from cancer-associated gene discovery to drug target validation. It also highlights the potential of using integration approach for cancer research. This unique and timely book provides a thorough overview of developing omics, which will appeal to anyone involved in cancer research. It will be a useful reference book for graduate students of different subjects (medicine, biology, engineering, etc) and senior scientists interested in the fascinating area of advanced technologies in cancer research. Readership: This is a precious book for all types of readers – cancer researchers, oncologists, pathologists, biologists, clinical chemists, pharmacologists, pharmaceutical specialists, biostatisticians, and bioinformaticists who want to expand their knowledge in cancer research.

Applications of NMR Spectroscopy

Applications of NMR Spectroscopy  Book
Author : Atta-ur-Rahman,M. Iqbal Choudhary
Publisher : Elsevier
Release : 2015-12-11
ISBN : 1608059626
Language : En, Es, Fr & De

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Book Description :

Applications of NMR Spectroscopy, Volume 1, originally published by Bentham and now distributed by Elsevier, presents the latest developments in the field of NMR spectroscopy, including the analysis of edible oils and lipid content in foods, the role of NMR spectroscopy in the human metabolomics and the diagnosis of autism-related disorders, protein-protein interactions, and NMR spectroscopy of chiral molecules. The fully illustrated chapters contain comprehensive references to the recent literature. The applications presented cover a wide range of the field, such as drug development, medical imaging and diagnostics, food science, mining, petrochemical, process control, materials science, and chemical engineering, making this resource a multi-disciplinary reference with broad applications. The content is ideal for readers who are seeking reviews and updates, as it consolidates scientific articles of a diverse nature into a single volume. Sections are organized based on disciplines, such as food science and medical diagnostics. Each chapter is written by eminent experts in the field. Consolidates the latest developments in NMR spectroscopy into a single volume Authored and edited by world-leading experts in spectroscopy Features comprehensive references to the most recent related literature More than 75 illustrations aid in the retention of key concepts

Cancer Metabolomics

Cancer Metabolomics Book
Author : Shen Hu
Publisher : Springer Nature
Release : 2021-05-03
ISBN : 3030516520
Language : En, Es, Fr & De

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Book Description :

Cancer metabolomics is a rapidly evolving field that aims for a comprehensive dissection of the metabolic phenotypes and functional network of metabolites in human cancers. State of the art metabolomics tools have been developed and applied to studying cancer metabolism and developing metabolic targets for improved diagnosis, prognosis and therapeutic treatment of human cancers. Chapters are written by subject experts in the field of cancer metabolomics with cross-disciplinary contributions. Coverage includes advanced metabolomics technologies and methodologies, including chemical isotope labelling liquid chromatography - mass spectrometry, capillary ion chromatography - mass spectrometry, 2-D gas chromatography – mass spectrometry, capillary electrophoresis – mass spectrometry, nuclear magnetic resonance spectroscopy, shotgun lipidomics, tracer-based metabolomics, microbial metabolomics, mass spectrometry imaging for single cell metabolomics and functional metabolomics. In addition, the book highlights new discoveries in cancer metabolism such as hypoxia inducible factor pathway, isocitrate dehydrogenase 1 mutation and oncometabolites. Finally, contributors focus on the translational applications of metabolomics in human cancers such as glioma, head and neck cancer, and gastric cancer. This new volume will be a unique reference source for cancer researchers and promote applications of metabolomics in understanding cancer metabolism.

Updates in Liver Cancer

Updates in Liver Cancer Book
Author : Hesham Abdeldayem
Publisher : BoD – Books on Demand
Release : 2017-04-05
ISBN : 9535130633
Language : En, Es, Fr & De

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Book Description :

Liver cancers result in considerable amount of financial and social burden. On the other hand, researches and clinical studies related to liver cancers continue to advance at a rapid pace. The chapters in this book provide state-of-the-art reviews on the current knowledge and advances in research and management of liver cancers. It includes the most recent advances in that field, particularly, hepatocarcinogenesis and the potential role of intestinal microbiota, nonalcoholic steatohepatitis, cancer stem cells, aldehyde dehydrogenase-1, and hepatitis B virus. This book also discusses the methods of diagnosis of HCC, the minimally invasive therapies for liver cancers, living donor liver transplantation for HCC, surgical management of liver metastases from colorectal cancers, and assessment and optimization for the future liver remnant.

50th ENC Conference

50th ENC Conference Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download 50th ENC Conference book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Methodologies for Metabolomics

Methodologies for Metabolomics Book
Author : Norbert W. Lutz,Jonathan V. Sweedler,Ron A. Wevers
Publisher : Cambridge University Press
Release : 2013-01-21
ISBN : 1139619055
Language : En, Es, Fr & De

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Book Description :

Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.

The Handbook of Metabonomics and Metabolomics

The Handbook of Metabonomics and Metabolomics Book
Author : John C. Lindon,Jeremy K. Nicholson,Elaine Holmes
Publisher : Elsevier
Release : 2011-08-11
ISBN : 9780080468006
Language : En, Es, Fr & De

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Book Description :

Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications. * comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies * aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification * covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.

Wiley Encyclopedia of Chemical Biology Volume 2

Wiley Encyclopedia of Chemical Biology  Volume 2 Book
Author : Tadhg P. Begley
Publisher : Wiley-Blackwell
Release : 2009-02-03
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

Wiley Encyclopedia of Chemical Biology Volume 3

Wiley Encyclopedia of Chemical Biology  Volume 3 Book
Author : Tadhg P. Begley
Publisher : Wiley
Release : 2009-02-03
ISBN : 9780470470190
Language : En, Es, Fr & De

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Book Description :

The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

Wiley encyclopedia of chemical biology

Wiley encyclopedia of chemical biology Book
Author : Tadhg P. Begley,John Wiley & Sons
Publisher : Unknown
Release : 2009
ISBN : 9780471754770
Language : En, Es, Fr & De

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Book Description :

Download Wiley encyclopedia of chemical biology book written by Tadhg P. Begley,John Wiley & Sons, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Wiley Encyclopedia of Chemical Biology Volume 4

Wiley Encyclopedia of Chemical Biology  Volume 4 Book
Author : Tadhg P. Begley
Publisher : Wiley-Blackwell
Release : 2009-02-03
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

New Scientist

New Scientist Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download New Scientist book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Philosophical Transactions

Philosophical Transactions Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Each issue of Transactions B is devoted to a specific area of the biological sciences, including clinical science. All papers are peer reviewed and edited to the highest standards. Published on the 29th of each month, Transactions B is essential reading for all biologists.

Chemistry and Industry

Chemistry and Industry Book
Author : Anonim
Publisher : Unknown
Release : 2012
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Proteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery Book
Author : Haleem J. Issaq,Timothy D. Veenstra
Publisher : Academic Press
Release : 2019-10-24
ISBN : 0128197889
Language : En, Es, Fr & De

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Book Description :

Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. This second edition has been fully updated and revised to address recent advances in MS and NMR instrumentation, high-field NMR, proteomics and metabolomics for biomarker validation, clinical assays of biomarkers and clinical MS and NMR, identifying microRNAs and autoantibodies as biomarkers, MRM-MS assay development, top-down MS, glycosylation-based serum biomarkers, cell surface proteins in biomarker discovery, lipodomics for cancer biomarker discovery, and strategies to design studies to identify predictive biomarkers in cancer research. Addresses the full range of proteomic and metabolomic methods and technologies used for biomarker discovery and validation Covers all steps involved in biomarker discovery, from study design to study execution Serves as a vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals and graduate students

Bioinformatics Methods in Clinical Research

Bioinformatics Methods in Clinical Research Book
Author : Rune Matthiesen
Publisher : Humana
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Integrated bioinformatics solutions have become increasingly valuable in past years, as technological advances have allowed researchers to consider the potential of omics for clinical diagnosis, prognosis, and therapeutic purposes, and as the costs of such techniques have begun to lessen. In Bioinformatics Methods in Clinical Research, experts examine the latest developments impacting clinical omics, and describe in great detail the algorithms that are currently used in publicly available software tools. Chapters discuss statistics, algorithms, automated methods of data retrieval, and experimental consideration in genomics, transcriptomics, proteomics, and metabolomics. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, provides practical examples illustrating methods, results, and conclusions from data mining strategies wherever possible, and includes a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Informative and ground-breaking, Bioinformatics Methods in Clinical Research establishes a much-needed bridge between theory and practice, making it an indispensable resource for bioinformatics researchers.

Pacific Symposium on Biocomputing

Pacific Symposium on Biocomputing Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Pacific Symposium on Biocomputing book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.