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Nicotine And Other Tobacco Compounds In Neurodegenerative And Psychiatric Diseases

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Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases

Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases Book
Author : Emilija Veljkovic,Wenhao Xia,Blaine Phillips,Ee Tsin Wong,Jenny Ho,Alberto Oviedo Casado,Julia Hoeng,Manuel Peitsch
Publisher : Academic Press
Release : 2018-01-15
ISBN : 0128129239
Language : En, Es, Fr & De

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Book Description :

Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases: Epidemiological Data on Smoking and Preclinical and Clinical Data on Nicotine provides a comprehensive summary of the epidemiological data on smoking and several neurological disorders, including Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis, Tourette’s syndrome, schizophrenia, anxiety, depression and ADHD, as well as preclinical and clinical data on the effects of nicotine. Despite the obvious and undisputed harmful nature of smoking, evidence suggests that some tobacco and tobacco smoke-derived constituents may offer neuroprotective effects, possibly in combinations, rather than individually. This unprecedented book describes the complex relationships between smoking and neurological disease and the bioactive compounds found in tobacco. It provides a comprehensive review of nicotine and other compounds found in tobacco plant, with scientific evidence of neuroprotective and anti-inflammatory effects that may act in conjunction with nicotine to exert neuroprotective effects observed in smokers. By presenting findings beyond harmful cigarette smoke effects, attention can be drawn to individual compounds of tobacco that may serve as inspiration for further therapy development. Presents the first comprehensive, tabulated summary of literature on the epidemiological data on smoking and neurological disease Includes preclinical and clinical data on nicotine in neurological diseases and mechanisms of action of nicotine in neuroprotection Features a comprehensive summary of non-nicotine smoke constituents with potentially neuroprotective and anti-inflammatory properties Discusses Multiple Sclerosis, Alzheimer’s disease, Parkinson’s Disease, Schizophrenia, Depression, ADHD, Anxiety and Tourette’s Syndrome in the context of smoking and nicotine

Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases

Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases Book
Author : Emilija Veljkovic,Wenhao Xia,Blaine Phillips,Jenny Ho,Ee Tsin Wong,Alberto Oviedo Casado,Julia Hoeng,Manuel Peitsch
Publisher : Academic Press
Release : 2018-01-03
ISBN : 9780128129227
Language : En, Es, Fr & De

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Book Description :

Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases: Epidemiological Data on Smoking and Preclinical and Clinical Data on Nicotine provides a comprehensive summary of the epidemiological data on smoking and several neurological disorders, including Alzheimer's disease, Parkinson's disease, Multiple Sclerosis, Tourette's syndrome, schizophrenia, anxiety, depression and ADHD, as well as preclinical and clinical data on the effects of nicotine. Despite the obvious and undisputed harmful nature of smoking, evidence suggests that some tobacco and tobacco smoke-derived constituents may offer neuroprotective effects, possibly in combinations, rather than individually. This unprecedented book describes the complex relationships between smoking and neurological disease and the bioactive compounds found in tobacco. It provides a comprehensive review of nicotine and other compounds found in tobacco plant, with scientific evidence of neuroprotective and anti-inflammatory effects that may act in conjunction with nicotine to exert neuroprotective effects observed in smokers. By presenting findings beyond harmful cigarette smoke effects, attention can be drawn to individual compounds of tobacco that may serve as inspiration for further therapy development. Presents the first comprehensive, tabulated summary of literature on the epidemiological data on smoking and neurological disease Includes preclinical and clinical data on nicotine in neurological diseases and mechanisms of action of nicotine in neuroprotection Features a comprehensive summary of non-nicotine smoke constituents with potentially neuroprotective and anti-inflammatory properties Discusses Multiple Sclerosis, Alzheimer's disease, Parkinson's Disease, Schizophrenia, Depression, ADHD, Anxiety and Tourette's Syndrome in the context of smoking and nicotine

Neuroscience of Nicotine

Neuroscience of Nicotine Book
Author : Victor R. Preedy
Publisher : Academic Press
Release : 2019-03-20
ISBN : 0128130369
Language : En, Es, Fr & De

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Book Description :

Neuroscience of Nicotine: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of nicotine addiction and its effects on the brain. Offering thorough coverage of all aspects of nicotine research, treatment, policy and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of nicotine misuse. With an estimated one billion individuals worldwide classified as tobacco users—and tobacco use often being synonymous with nicotine addiction—nicotine is one of the world’s most common addictive substances, and a frequent comorbidity of misuse of other common addictive substances. Nicotine alters a variety of neurological processes, from molecular biology, to cognition, and quitting is exceedingly difficult because of the number of withdrawal symptoms that accompany the process. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of nicotine use, along with its effects on neurobiological function Discusses nicotine use as a component of dual-use and poly addictions and outlines numerous screening and treatment strategies for misuse Covers both the physical and psychological effects of nicotine use and withdrawal to provide a fully-formed view of nicotine dependency and its effects

Toxicological Evaluation of Electronic Nicotine Delivery Products

Toxicological Evaluation of Electronic Nicotine Delivery Products Book
Author : Manuel Peitsch,Julia Hoeng
Publisher : Academic Press
Release : 2021-01-14
ISBN : 0128209356
Language : En, Es, Fr & De

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Book Description :

Toxicological Evaluation of Electronic Nicotine Delivery Products (ENDP) discusses the scientific basis for the toxicological assessment and evaluation of ENDPs. The book covers aerosol chemistry, in vitro and in vivo studies as well as clinical studies. It provides the basis for the evaluation of short and long term-effects, along with relative risks. It also examines the potential role of ENDPs in tobacco harm reduction and how they may reduce the risk of disease in smokers who switch to them. This book is a comprehensive resource for toxicologists, health practitioners and public health professionals who want the scientific information necessary to assess the relative risk of ENDPs when compared with cigarette smoking and cessation. Delivers a comprehensive overview of current state of science Offers an integrated analysis of e-cigarettes and heated tobacco products Provides guidance for methodologies

Brain effects of Nicotine and derived compounds

Brain effects of Nicotine and derived compounds Book
Author : Valentina Echeverria Moran
Publisher : Frontiers E-books
Release : 2022-01-20
ISBN : 2889191419
Language : En, Es, Fr & De

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Book Description :

Epidemiological studies have associated tobacco consumption with a lower incidence of Alzheimer’s disease (AD) and Parkinson’s disease (PD). The neuroprotective effect of tobacco has been mainly attributed to the stimulation by nicotine of the a7 nicotinic acetylcholine receptors (nAChRs), which are implicated in neuronal survival, attention, and memory. A reduction in cholinergic function including lower levels of the expression of nAChRs in the hippocampus correlates with memory impairment in AD and schizophrenia. nicotine main metabolite cotinine shows similar neuroprotective and mnemonic properties. Also cotinine reduced Alzheimer’s pathology in a mouse model of the disease. Tobacco-derived compounds can be beneficial in a broad range of neurological disorders such as schizophrenia, AD, attention-deficit hyperactivity disorder, and PD as well as in diminishing tobacco withdrawal. In the latest years numerous new discoveries in this research area have been achieved and a Research Topic publication is needed.

Brain Protection in Schizophrenia Mood and Cognitive Disorders

Brain Protection in Schizophrenia  Mood and Cognitive Disorders Book
Author : Michael S. Ritsner
Publisher : Springer Science & Business Media
Release : 2010-06-16
ISBN : 904818553X
Language : En, Es, Fr & De

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Book Description :

Neuroprotection is a novel perspective for the treatment of disorders that lead to neurodegeneration and disabilities as a result of deterioration of neurons due to apoptosis, oxidative stress, excitotoxicity, and other mechanisms. These mechanisms have implications not only for neurodegenerative disorders, but also for schizophrenia, mood and cognitive disorders. The purpose of this book is to provide an up-to-date overview of basic and clinical studies concerning the neuroprotective approach, mechanisms, and several compounds with neuroprotective properties that may contribute to more efficacious treatment of major mental health disorders. The book is divided into two sections. The first section serves as an introduction and overview of conceptual issues of the neuroprotective approach, and some neurobiological advances. Chapters in this section review definitions, perspectives, and issues that provide a conceptual base for the rest of the book. In addition, this part includes chapters in which the authors present and discuss the findings from basic studies of neurodegenerative mechanisms that are associated with the pathogenesis of major mental health disorders. The second section focuses on findings obtained from clinical trials with neuroprotective compounds, and neuromodulatory techniques. The take-home message is that principles of the neuroprotective approach may be applied to treatment of schizophrenia, mood and cognitive disorders. Contributors to this book are among the most active investigators and clinicians in the field who provide new perspectives not only clarifying ongoing controversies but also propose diverse aspects and new insights to neuroprotection. This book is intended for a broad readership, which includes a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, graduate students, and policy makers in the fields of mental health.

Neuropsychiatric Disorders and Epigenetics

Neuropsychiatric Disorders and Epigenetics Book
Author : Dag Yasui,Jacob Peedicayil,Dennis R. Grayson
Publisher : Academic Press
Release : 2016-11-15
ISBN : 0128005270
Language : En, Es, Fr & De

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Book Description :

Neuropsychiatric Disorders and Epigenetics is a comprehensive reference for the epigenetic basis of most common neuropsychiatric disorders. The volume is organized into chapters representing individual neuropsychiatric disorders, from addition to obesity contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects of environmental stimuli on epigenetic states is particularly relevant o disease. Recent discoveries in epigenetic research enabled by epic advances in genomic technologies have positioned the field for broad translation to therapeutic interventions for previously unmanageable disorders Neuropsychiatric disorders represent a prime target of epigenetic interventions as they are highly debilitating, often chronic diseases with enormous costs to society. Thus, this volume will help define epigenetics as a key player in neuropsychiatric disorders, highlighting the full spectrum of epigenetic mechanisms underlying such disorders and introducing the vast range of epigenetic therapies under development. Analyzes the effects of environmental stimuli on epigenetic states that correlate with neuropsychiatric disease induction Reviews the epigenetic basis for common neuropsychiatric disorders, thereby guiding translational therapies for clinicians and mechanistic studies for scientists Extensive use of diagrams, illustrations, tables, and graphical abstracts for each section providing rapid assessment

Nicotine in Psychiatry

Nicotine in Psychiatry Book
Author : Melissa P. Piasecki,Paul Newhouse
Publisher : American Psychiatric Pub
Release : 2008-11-01
ISBN : 1585628298
Language : En, Es, Fr & De

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Book Description :

Today, 25% of Americans smoke and 50% of smokers die from tobacco-related illnesses. Meanwhile, little attention has been given to implementing cessation therapies for our patients who smoke. Nicotine in Psychiatry: Psychopathology and Emerging Therapeutics examines this timely subject. The book's contributors, subject matter experts in the growing field of nicotine neurobiology andclinical pharmacology, cover the latest knowledge on The pharmacokinetics and pharmacodynamics of nicotine The effect of nicotinic receptors on the central nervous system (CNS), the recent advances made in understanding the normal function of these receptors, and how this knowledge transfers to the clinical treatment of many CNS disorders Behavioral factors influencing the effects of nicotine and nicotine's addictive capacity The association between smoking and specific mental disorders and the association between nicotine and mood Clinical applications of nicotine as a potential therapeutic agent for a variety of disorders, such as attention deficit, Alzheimer's and Parkinson's diseases, epilepsy, inflammatory bowel disease, schizophrenia, and Tourette's syndrome Nicotine replacement therapies and various smoking-cessation strategies This book makes fascinating reading for anyone interested in the recent tobacco public policy debates, as well as clinicians and researchers looking for current information on nicotine and its clinical applications.

Functional Foods and Nutraceuticals in Metabolic and Non communicable Diseases

Functional Foods and Nutraceuticals in Metabolic and Non communicable Diseases Book
Author : Ram B. Singh
Publisher : Academic Press
Release : 2021-11-30
ISBN : 0128231750
Language : En, Es, Fr & De

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Book Description :

Functional Foods and Nutraceuticals in Metabolic and Non-communicable Diseases presents strategies for the prevention of non-communicable diseases and undernutrition through the use of functional foods and nutraceuticals. Research has shown that the use of certain functional foods and nutraceuticals, including spices, herbs, and millets, animal foods and plant foods can play a role in the treatment and prevention of various diseases and in health promotion. Finally, the book explores epigenetic modulation as a new method for the development of functional foods and functional farming. Intended for nutritionists, food scientists and those working in related health science professions, this book contributes to the discussions focused on nutritional transition, globalization, how to administer foods in the treatment of metabolic syndrome, hypertension, diabetes, heart attacks, neuropsychiatric disorders, bone and joint diseases, and carcinogenesis. Places emphasis on food diversity to provide perfect combinations of nutritional ingredients Presents the utility and necessity of functional food production for health promotion Offers suggestions to increase functional food production while simultaneously decreasing production costs

Biomarkers and Mental Illness

Biomarkers and Mental Illness Book
Author : Paul C. Guest
Publisher : Springer
Release : 2016-12-02
ISBN : 3319460889
Language : En, Es, Fr & De

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Book Description :

Employing accessible language throughout, this book covers the history of psychiatric research, the current state-of-the art in psychiatric practice, the physiological systems affected by psychiatric illnesses, the whole-body nature of these diseases and the impact that this aspect has on emerging biomarker discoveries. Further, it provides descriptions of the major specific psychiatric disorders and the special challenges regarding the diagnosis and treatment of each. The book concludes with insights into the latest developments in hand-held biomarker test devices, which can provide diagnostic information in less than 15 minutes in point-of-care settings. This book investigates the emerging use of biomarkers in the study of psychiatric diseases, a topic of considerable importance for a broad range of people including researchers, clinicians, psychiatrists, university students and even those whose lives are affected in some way by a psychiatric illness. The last category is hardly trivial, since a staggering one in three people worldwide show the criteria for at least one psychiatric disorder at some point in their lifetime.

Endocrine Disruptors and Puberty

Endocrine Disruptors and Puberty Book
Author : Evanthia Diamanti-Kandarakis,Andrea C. Gore
Publisher : Springer Science & Business Media
Release : 2011-12-01
ISBN : 9781607615613
Language : En, Es, Fr & De

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Book Description :

Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole. Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical challenge. In this respect, puberty, a crucial developmental stage, has been definitively identified as a key window of vulnerability with regard to endocrine disruptors. Written by leading authorities in the field, Endocrine Disruptors and Puberty offers an engaging and comprehensive overview of this fascinating and rapidly growing problem. An indispensable resource for all clinicians and scientists interested in this challenging endocrinologic topic, Endocrine Disruptors and Puberty is a timely contribution that will help navigate a path toward understanding the problem and developing solutions.

Research Awards Index

Research Awards Index Book
Author : Anonim
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Research Awards Index book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Advanced Practice Psychiatric Nursing

Advanced Practice Psychiatric Nursing Book
Author : Joyce J. Fitzpatrick, PhD, MBA, RN, FAAN
Publisher : Springer Publishing Company
Release : 2012-08-21
ISBN : 0826108717
Language : En, Es, Fr & De

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Book Description :

Named a 2013 Doody's Core Title! "There are few new books to direct PMH-APRN treatment options...Now, this book provides the path to integration of treatment options for the holistic care of psychiatric client by PMH-APRNs."--Doody's Medical Reviews ìThis text is a wonderful compilation of information that is needed within current advanced practice psychiatric mental health nursing. The chapters are informative, have excellent references and provide up to the minute information that is grounded in evidence-based practices.î Barbara Jones Warren, PhD, RN, CNS-BC, PMH, FAAN Professor, Clinical Nursing Director, Psychiatric Nursing Specialty National Institutes of Health/American Nurses Association Ethnic/Racial Minority Fellow The Ohio State College of Nursing This groundbreaking core text fills a void in nursing literature by integrating psychotherapy, psychopharmacology, and complementary and alternative medicine (CAM) approaches into advanced practice nursing. It is organized around psychiatric "syndromes" rather than DSM diagnoses, so it will remain current even after the publication of the DSM-5. The book provides clear and relevant treatment options in the form of decision trees with additional explanatory narratives. These decision trees enable practitioners to distinguish ìnormalî patients from those who require more customized therapeutic interventions. This holistic text integrates neurobiology, theory, and research evidence related to psychotherapy, psychopharmacology, and complementary and alternative medicine interventions. While providing comprehensive information on theory and practice, it simplifies complex aspects of treatment with clarity and provides the depth of content appropriate to support sound clinical reasoning required in advanced practice. The book responds to the current backlash against overmedication in psychiatry. It also fulfills the upcoming requirements by APNA and ISPN that advanced practice psychiatric nurses must have skills in psychotherapy. Additionally, the text focuses on treatment issues across the life span and highlights pertinent clinical differences from the adult population through pediatric pointers and aging alerts. Advanced Practice Psychiatric Nursing reflects the extensive practice and educational experience of editors and contributors from the United States, Canada, and Scotland, all of whom are expert APNs. Key Features: Organized around psychiatric ìsyndromes,î rather than DSM diagnoses, so it will remain relevant after the DSM-5 is published Integrates neurobiology, theory, and research evidence related to psychotherapy. psychopharmacology, and CAM therapies Provides the much-needed content on psychotherapy newly required for all psychiatric advanced practice nurses (APNA & ISPN White Papers) Supports clinical decision skills through thoughtfully designed, easy-to-follow decision trees ICONS highlight life span clinical management differences through Pediatric Pointers and Aging Alerts

Lowinson and Ruiz s Substance Abuse

Lowinson and Ruiz s Substance Abuse Book
Author : Pedro Ruiz,Eric C. Strain
Publisher : Lippincott Williams & Wilkins
Release : 2011
ISBN : 1605472778
Language : En, Es, Fr & De

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Book Description :

"A comprehensive, authoritative text on all aspects of substance abuse and addiction medicine. Scientific topics such as the biology of various addictions and all dimensions of clinical treatment and management are addressed by a wide range of leading contributors. Behavioral addictions are addressed also, so the text is not solely devoted to specific substances and their misuse"--Provided by publisher.

Antioxidants in Food Vitamins and Supplements

Antioxidants in Food  Vitamins and Supplements Book
Author : Amitava Dasgupta,Kimberly Klein
Publisher : Academic Press
Release : 2014-02-11
ISBN : 0124059171
Language : En, Es, Fr & De

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Book Description :

Antioxidants in Food, Vitamins and Supplements bridges the gap between books aimed at consumers and technical volumes written for investigators in antioxidant research. It explores the role of oxidative stress in the pathophysiology of various diseases as well as antioxidant foods, vitamins, and all antioxidant supplements, including herbal supplements. It offers healthcare professionals a rich resource of key clinical information and basic scientific explanations relevant to the development and prevention of specific diseases. The book is written at an intermediate level, and can be easily understood by readers with a college level chemistry and biology background. Covers both oxidative stress-induced diseases as well as antioxidant-rich foods (not the chemistry of antioxidants) Contains easy-to-read tables and figures for quick reference information on antioxidant foods and vitamins Includes a glycemic index and a table of ORAC values of various fruits and vegetables for clinicians to easily make recommendations to patients

Cumulated Index Medicus

Cumulated Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cumulated Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neurodegenerative Disease and Micronutrients

Neurodegenerative Disease and Micronutrients Book
Author : Kedar N. Prasad
Publisher : CRC Press
Release : 2014-10-13
ISBN : 1482210479
Language : En, Es, Fr & De

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Book Description :

The book proposes that a preparation of antioxidants and micronutrients, in combination with standard therapy, may reduce progression and improve management better than standard therapy alone for Alzheimer’s, Parkinson’s, and Huntington’s disease, as well as PTSD, traumatic brain injury, concussions, and cerebral vascular insufficiency. The book presents the latest research on the effects of micronutrients and recommends formulations for use in combination with standard therapies for these neurodegenerative diseases and conditions.

Peripheral Markers of Immune Response in Major Psychiatric Disorders Where Are We Now and Where Do We Want to Be

Peripheral Markers of Immune Response in Major Psychiatric Disorders  Where Are We Now and Where Do We Want to Be  Book
Author : Błażej Misiak,Dorota Frydecka,Bartłomiej Stańczykiewicz,Jerzy Samochowiec
Publisher : Frontiers Media SA
Release : 2019-04-03
ISBN : 2889457974
Language : En, Es, Fr & De

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Book Description :

Major psychiatric disorders, including schizophrenia, bipolar disorder and major depression represent complex phenotypes with imprecise diagnostic boundaries. It has been found that these disorders can be characterized by a number of peripheral immune-inflammatory alterations, including, i.e. elevated levels of pro-inflammatory cytokines, increased levels of specific and non-specific antibodies or abnormal counts of lymphocyte subpopulations. Although it has been found that major psychiatric disorders share similar dysregulations of immune-inflammatory response, recent studies have also clearly demonstrated that some differences can be indicated. Interestingly, certain immune-inflammatory disturbances appear to be state markers, since they occur in acute relapse and normalize following pharmacological treatment, while the rest represents trait markers that remain stable regardless of treatment. It is also important to note that peripheral immune-inflammatory markers have been associated with psychopathological manifestation of major psychiatric disorders, response to treatment and long-term outcomes. However, it remains unclear what is the origin of peripheral inflammation in psychiatric disorders. To date, several mechanisms have been proposed, including the gut-brain axis dysregulation, infections in the neurodevelopmental period or immunogenetic factors. This eBook summarizes current evidence from studies investigating peripheral inflammation in schizophrenia, bipolar disorder, major depression and post-traumatic stress disorder as well as it provides future directions for the field.

Parkinson s Disease and Related Disorders

Parkinson s Disease and Related Disorders Book
Author : Peter Riederer,Heinz Reichmann,Moussa B. H. Youdim,Manfred Gerlach
Publisher : Springer Science & Business Media
Release : 2006-11-23
ISBN : 3211452958
Language : En, Es, Fr & De

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Book Description :

This book gives a comprehensive overview on current clinical and basic research issues related to Parkinson’s disease and its related disorders. The book is the result of the 16th International Congress of Parkinson’s Disease and Related disorders congress 2005. Its contents are suitable for neurologists, psychiatrists, neurosurgeons, basic researchers, geneticians and patients as well as their relatives.

Encyclopedia of Psychopharmacology

Encyclopedia of Psychopharmacology Book
Author : Ian Stolerman
Publisher : Springer Science & Business Media
Release : 2010-07-31
ISBN : 3540686983
Language : En, Es, Fr & De

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Book Description :

Here is a broad overview of the central topics and issues in psychopharmacology, biological psychiatry and behavioral neurosciences, with information about developments in the field, including novel drugs and technologies. The more than 2000 entries are written by leading experts in pharmacology and psychiatry and comprise in-depth essays, illustrated with full-color figures, and are presented in a lucid style.