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Neurotechnology And Brain Stimulation In Pediatric Psychiatric And Neurodevelopmental Disorders

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Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders

Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders Book
Author : Lindsay M. Oberman,Peter G. Enticott
Publisher : Academic Press
Release : 2018-11-27
ISBN : 0128127783
Language : En, Es, Fr & De

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Book Description :

Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders provides a comprehensive overview of neurotechnological devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents. Many neuropsychiatric disorders are covered such as Autism Spectrum Disorder, ADHD, Depression, Tourette’s Syndrome, and OCD. Different device-based treatments are discussed such as Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, Deep Brain Stimulation, Chronotherapy, and Neurofeedback. Provides an overview of neuromodulatory devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents Gives evidence-based recommendations for non-drug interventions that may be effective for treatment options Discusses different neuromodulatory treatment options, including TMS, tDCS, DBS, chronotherapy and neurofeedback

Non invasive Brain Stimulation NIBS in Neurodevelopmental Disorders

Non invasive Brain Stimulation  NIBS  in Neurodevelopmental Disorders Book
Author : Anonim
Publisher : Elsevier
Release : 2021-06-22
ISBN : 0128223472
Language : En, Es, Fr & De

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Book Description :

Non-invasive Brain Stimulation (NIBS) in Neurodevelopmental Disorders, Volume 264 presents the latest updates on recent techniques used to examine the potential treatment of psychiatric and neurological disorders in adults. In this special issue, the book's authors and contributors provide a unique focus on the potential effects of non-invasive brain stimulation. Topics cover a range of reviews, opinions, methodologies, original research articles, and suggestions on how to better translate scientific knowledge into practice. This new release will help guide basic research and the development of therapeutic interventions for children and adolescents who suffer from neurodevelopmental disorders. Covers the effects of brain stimulation on different neurodevelopmental disorders Includes experimental studies in humans, animals and associated theoretical reviews Provides the most accurate and up-to-date coverage from selected international experts

Frontiers in Brain Based Therapeutic Interventions and Biomarker Research in Child and Adolescent Psychiatry

Frontiers in Brain Based Therapeutic Interventions and Biomarker Research in Child and Adolescent Psychiatry Book
Author : Paul E. Croarkin,Stephanie H. Ameis
Publisher : Frontiers Media SA
Release : 2016-08-05
ISBN : 2889199541
Language : En, Es, Fr & De

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Book Description :

Developmental neuroscience research is on the cusp of unprecedented advances in the understanding of how variations in brain structure and function within neural circuits confer risk for symptoms of childhood psychiatric disorders. Novel dimensional approaches to illness classification, the availability of non-invasive, diverse and increasingly sophisticated methods to measure brain structure and function in humans in vivo, and advances in genetics, animal model and multimodal research now place brain-based biomarkers within reach in the field of psychiatry. These advances hold great promise for moving neuroscience research into the clinical realm. One exciting new area of translational research in child and adolescent psychiatry, is in the use of a variety of neuroscience research tools to track brain response to clinical intervention. Examples of this include: using longitudinal neuroimaging techniques to track changes in white matter microstructure following a training intervention for children with poor reading skills, or using functional imaging to compare brain activity before and after children with bipolar disorder begin taking psychotropic medication treatment. Brain stimulation is another cutting-edge research area where brain response to therapeutic intervention can be closely tracked with electroencephalography or other brain imaging modalities. Research using neuroscience tools to track brain response to clinical interventions is beginning to yield novel insights into the etiopathogenesis of psychiatric illness, and is providing preliminary feedback around how therapeutic interventions work in the brain to bring about symptom improvement. Using these novel approaches, neuroscience research may soon move into the clinical realm to target early pathophysiology, and tailor treatments to both individuals and specific neurodevelopmental trajectories, in an effort to alter the course of development and mitigate risk for a lifetime of morbidity and ineffective treatments. Excitement and progress in these areas must be tempered with safety and ethical considerations for these vulnerable populations. This research topic focuses on efforts to use neuroscience research tools to identify brain-based biomarkers of therapeutic response in child and adolescent psychiatry.

Transcranial Direct Current Stimulation in Neuropsychiatric Disorders

Transcranial Direct Current Stimulation in Neuropsychiatric Disorders Book
Author : André R. Brunoni
Publisher : Springer Nature
Release : 2021-09-25
ISBN : 3030761363
Language : En, Es, Fr & De

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Book Description :

Download Transcranial Direct Current Stimulation in Neuropsychiatric Disorders book written by André R. Brunoni, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neurofeedback and Neuromodulation Techniques and Applications

Neurofeedback and Neuromodulation Techniques and Applications Book
Author : Robert Coben,James R. Evans
Publisher : Academic Press
Release : 2010-11-25
ISBN : 9780123822369
Language : En, Es, Fr & De

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Book Description :

The study of neurofeedback and neuromodulation offer a window into brain physiology and function, suggesting innovative approaches to the improvement of attention, anxiety, pain, mood and behavior. Resources for understanding what neurofeedback and neuromodulation are, how they are used, and to what disorders and patients they can be applied are scarce, and this volume serves as an ideal tool for clinical researchers and practicing clinicians in both neuroscience and psychology to understand techniques, analysis, and their applications to specific patient populations and disorders. The top scholars in the field have been enlisted, and contributions offer both the breadth needed for an introductory scholar and the depth desired by a clinical professional. Includes the practical application of techniques to use with patients Includes integration of neurofeedback with neuromodulation techniques Discusses what the technique is, for which disorders it is effective, and the evidence basis behind its use Written at an appropriate level for clinicians and researchers

The Neuroscience of Hallucinations

The Neuroscience of Hallucinations Book
Author : Renaud Jardri,Arnaud Cachia,Pierre Thomas,Delphine Pins
Publisher : Springer Science & Business Media
Release : 2012-09-25
ISBN : 1461441218
Language : En, Es, Fr & De

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Book Description :

Hallucinatory phenomena have held the fascination of science since the dawn of medicine, and the popular imagination from the beginning of recorded history. Their study has become a critical aspect of our knowledge of the brain, making significant strides in recent years with advances in neuroimaging, and has established common ground among what normally are regarded as disparate fields. The Neuroscience of Hallucinations synthesizes the most up-to-date findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. In recognition of the wide audience for this information among the neuroscientific, medical, and psychology communities, its editors bring a mature evidence base to highly subjective experience. This knowledge is presented in comprehensive detail as leading researchers across the disciplines ground readers in the basics, offer current cognitive, neurobiological, and computational models of hallucinations, analyze the latest neuroimaging technologies, and discuss emerging interventions, including neuromodulation therapies, new antipsychotic drugs, and integrative programs. Among the topics covered: Hallucinations in the healthy individual. A pathophysiology of transdiagnostic hallucinations including computational and connectivity modeling. Molecular mechanisms of hallucinogenic drugs. Structural and functional variations in the hallucinatory brain in schizophrenia. The neurodevelopment of hallucinations. Innovations in brain stimulation techniques and imaging-guided therapy. Psychiatrists, neurologists, neuropsychologists, cognitive neuroscientists, clinical psychologists, and pharmacologists will welcome The Neuroscience of Hallucinations as a vital guide to the current state and promising future of their shared field.

Oxford Handbook of Neuroethics

Oxford Handbook of Neuroethics Book
Author : Judy Illes,Barbara J. Sahakian
Publisher : OUP Oxford
Release : 2011-04-07
ISBN : 0191620912
Language : En, Es, Fr & De

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Book Description :

The past two decades have seen unparalleled developments in our knowledge of the brain and mind. However, these advances have forced us to confront head-on some significant ethical issues regarding our application of this information in the real world- whether using brain images to establish guilt within a court of law, or developing drugs to enhance cognition. Historically, any consideration of the ethical, legal, and social implications of emerging technologies in science and medicine has lagged behind the discovery of the technology itself. These delays have caused problems in the acceptability and potential applications of biomedical advances and posed significant problems for the scientific community and the public alike - for example in the case of genetic screening and human cloning. The field of Neuroethics aims to proactively anticipate ethical, legal and social issues at the intersection of neuroscience and ethics, raising questions about what the brain tells us about ourselves, whether the information is what people want or ought to know, and how best to communicate it. A landmark in the academic literature, the Oxford Handbook of Neuroethics presents a pioneering review of a topic central to the sciences and humanities. It presents a range of chapters considering key issues, discussion, and debate at the intersection of brain and ethics. The handbook contains more than 50 chapters by leaders from around the world and a broad range of sectors of academia and clinical practice spanning the neurosciences, medical sciences and humanities and law. The book focuses on and provides a platform for dialogue of what neuroscience can do, what we might expect neuroscience will do, and what neuroscience ought to do. The major themes include: consciousness and intention; responsibility and determinism; mind and body; neurotechnology; ageing and dementia; law and public policy; and science, society and international perspectives. Tackling some of the most significant ethical issues that face us now and will continue to do so over the coming decades, The Oxford Handbook of Neuroethics will be an essential resource for the field of neuroethics for graduate students and postdoctoral fellows, basic scientists in the neurosciences and psychology, scholars in humanities and law, as well as physicians practising in the areas of primary care in neurological medicine.

The Safety and Efficacy of Noninvasive Brain Stimulation in Development and Neurodevelopmental Disorders

The Safety and Efficacy of Noninvasive Brain Stimulation in Development and Neurodevelopmental Disorders Book
Author : Lindsay M. Oberman,Peter G. Enticott
Publisher : Frontiers Media SA
Release : 2015-12-03
ISBN : 2889196992
Language : En, Es, Fr & De

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Book Description :

Noninvasive brain stimulation (including Transcranial Magnetic Stimulation (TMS) and Transcranial Current Brain Stimulation (TCS)) can be used both experimentally and therapeutically. In the experimental domain TMS can be applied in single pulses to depolarize a small population of neurons in a targeted brain region. This protocol can be used, for example, to map cortical motor outputs, study central motor conduction time, or evaluate the cortical silent period (a measure of intracortical inhibition) all of which are relevant to neurodevelopment. TMS can also be applied in pairs of pulses (paired pulse stimulation, ppTMS) where two pulses are presented in rapid succession to study intracortical inhibition and facilitation. Trains of repeated TMS (rTMS) pulses can be applied at various stimulation frequencies and patterns to modulate local cortical excitability beyond the duration of the stimulation itself. Depending on the parameters of stimulation the excitability can be either facilitated or suppressed. TCS (including Transcranial Direct Current Stimulation (tDCS), alternating current (tACS), and random noise current stimulation (tRNS) also have the potential to modulate cortical excitability and have also been used to study and modulate cortical activity in healthy and patient populations. The after-effects of rTMS and TCS are thought to be related to changes in efficacy (in either the positive or negative direction) of synaptic connections of the neurons being stimulated, thus these techniques have been used to study and modulate cortical plasticity mechanisms in a number of populations. Recently, researchers have begun to apply these techniques to the study of neurodevelopmental mechanisms as well as the pathophysiology and development of novel treatments for neurodevelopmental disorders. Though there is much promise, caution is warranted given the vulnerability of pediatric and clinical populations and the potential that these techniques have to modify circuit development in a cortex that is in a very dynamic state. This Research Topic hopes to provide an opportunity to share ideas across areas (human and animal researchers, clinicians and basic scientists). We are particularly interested in papers that address issues of choosing a protocol (intensity, frequency, location, coil geometry etc.), populations where noninvasive brain stimulation may have direct impact on diagnostics and treatment, as well as the safety and ethics of applying these techniques in pediatric populations. As many may not be aware of the potential and limitations of noninvasive brain stimulation and its use for research and treatment in this area, this Research Topic promises to have broad appeal. Submissions for all Frontiers article types are encouraged.

Rhythmic Stimulation Procedures in Neuromodulation

Rhythmic Stimulation Procedures in Neuromodulation Book
Author : James R. Evans,Robert Turner
Publisher : Academic Press
Release : 2017-06-24
ISBN : 0128037474
Language : En, Es, Fr & De

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Book Description :

Rhythmic Stimulation Procedures in Neuromodulation offers a unique approach to rhythm-related stimulation as it pertains to modulating neural functioning, with the goal of alleviating symptoms of mental disorder. Rhythm and related concepts (frequency, resonance, entrainment) are thought by many to be closely linked to human health and disease. Neurologists and clinical psychologists facilitate neuroplasticity by using pulsed (rhythmic) sensory or electromagnetic stimulation—a group of techniques broadly referred to as neuromodulation. This edited volume describes details of rhythm-related neuromodulation techniques, and experts in the field have detailed the pros and cons of each approach, citing both clinical and scientific support. Each technique chapter provides a detailed description of the procedure, a rationale for application with specific populations, discussion of similarities/differences relative to other approaches, and support for efficacy. This volume offers readers a historical overview of the roles of rhythm and dysrhythmia in health and disease, including examples of past and present therapeutic uses of rhythmic stimulation, entrainment, and/or modification. It also facilitates speculation about potential developments in rhythm-related methods for the future of mental health. Few books published in the general area of rhythm have focused on the scientific study of the significance of biological rhythms. Discusses features of the generally unknown early history of using rhythmic stimulation procedures in treating various disorders Provides an overview of the extent to which rhythmic stimulation of various types are basic to the majority of alternative and complementary medicine fields Provides details of several of today’s more commonly used stimulation techniques for neuromodulation, discussing the theoretical foundations and limitations of each, and providing clinical and scientific research evidence for their treatment efficacy in specific applications Discusses current directions in which stimulation techniques are moving and speculates on the promise they hold for major changes in mental health care

Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders

Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders Book
Author : Moyra Smith
Publisher : Academic Press
Release : 2021-04-25
ISBN : 0128232528
Language : En, Es, Fr & De

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Book Description :

Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders connects neurodevelopment with genetics and behavior to better understand the underlying factors leading to cognitive neurodevelopmental disorders. This book focuses on mechanisms of disease and follows the development of specific brain regions, functions, and gene expression to causes and processes in autism, attention deficit disorder, and learning disabilities. Topics include brain mapping, brain plasticity, epigenetics, neuroimmunology, and many other factors that influence the development of these diseases. This book will promote understanding of recent investigations and developments related to brain development from fetal life onward with specific relevance to neurodevelopmental cognitive disorders and conditions. This is an essential reference for anyone who is looking to learn more about different aspects of neurodevelopment and emerging concepts in psychiatric disorders. Discusses links between brain development, gene expression, and brain function Covers neural stem cells, proliferation, migration, differentiation, and neurogenesis Includes brain mapping, brain plasticity, epigenetics, neuroimmunology, and more Provides insight into causation and brain function in autism, attention deficit disorder, and learning disabilities Examines impact of society and environmental factors on mental health

Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences

Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences Book
Author : Bernardo Dell'Osso,Giorgio Di Lorenzo
Publisher : Springer Nature
Release : 2020-09-01
ISBN : 3030433560
Language : En, Es, Fr & De

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Book Description :

This book presents the state of the art regarding the use of non-invasive brain stimulation (TMS and tDCS) in the research and treatment of neuropsychiatric disorders. The contributions, all of which were prepared by internationally recognized experts in the field, are divided into two main sections (for TMS and tDCS, respectively) across diagnoses, following an introductory section on the mechanisms of action and neurophysiological background. Neuropsychological perspectives and approaches are provided as well. The book is ultimately intended to offer a unique, integrated approach to the use of non-invasive brain stimulation across the clinical neurosciences, providing a comprehensive and updated perspective that will benefit psychiatrists, neurologists, clinical psychologists and neurophysiologists alike.

Neuroethics

Neuroethics Book
Author : Judy Illes
Publisher : Oxford University Press
Release : 2017-08-17
ISBN : 019109045X
Language : En, Es, Fr & De

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Book Description :

Over the last decade, there have been unparalleled advances in our understanding of brain sciences. But with the development of tools that can manipulate brain function, there are pressing ethical implications to this newfound knowledge of how the brain works. In Neuroethics: Anticipating the Future, a distinguished group of contributors tackle current and critical ethical questions and offer forward-looking insights. What new balances should be struck between diagnosis and prediction, or invasive and non-invasive interventions, given the rapid advances in neuroscience? Are new criteria needed for the clinical definition of death for those eligible for organ donation? As data from emerging technologies are made available on public databases, what frameworks will maximize benefits while ensuring privacy of health information? These challenging questions, along with numerous other neuroethical concerns, are discussed in depth. Written by eminent scholars from diverse disciplines including neurology and neuroscience, ethics and law, public health and philosophy, this new volume on neuroethics sets out the many necessary considerations for the future. It is essential reading for the field of neuroethics, neurosciences and psychology, and an invaluable resource for physicians in neurological medicine, academics in humanities and law, and health policy makers.

Neuropsychiatry An Issue of Psychiatric Clinics of North America E Book

Neuropsychiatry  An Issue of Psychiatric Clinics of North America  E Book Book
Author : Vassilis E Koliatsos
Publisher : Elsevier Health Sciences
Release : 2020-05-26
ISBN : 0323789528
Language : En, Es, Fr & De

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Book Description :

This issue of Psychiatric Clinics, guest edited by Dr. Vassilis E. Koliatsos will cover Neuropsychiatry. This issue is one of four each year selected by our series consulting editor, Dr. Harsh Trivedi of Sheppard Pratt Health System. Topics in this issue include: The clinical neurobiology of autism spectrum disorders; New developments in impulse control disorders; Schizophrenia as a neurodevelopmental phenotype; Neuropsychiatric Aspects of Epilepsy; New developments in addiction; The clinical neuroscience of acquired brain injury; New developments in frontotemporal dementia; Lewy body degenerations as neuropsychiatric disorders; Neuropsychiatric challenges in Alzheimer’s disease; and New pharmacological approaches in Neuropsychiatry, among others.

At Risk for Neuropsychiatric Disorders An Affective Neuroscience Approach to Understanding the Spectrum

At Risk for Neuropsychiatric Disorders  An Affective Neuroscience Approach to Understanding the Spectrum Book
Author : Raymond C. K. Chan,Morten L. Kringelbach
Publisher : Frontiers Media SA
Release : 2016-11-17
ISBN : 2889450260
Language : En, Es, Fr & De

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Book Description :

Neuropsychiatric disorders such as schizophrenia, bipolar disorder, depression, anxiety disorders, and other mental disorders constitute about 13% of the global burden of disease surpassing both cardiovascular disease and cancer. The total cost worldwide of these diseases is estimated to exceed 100 million disability-adjusted life years. In order to begin to address this important problem, the present Research Topic brings together a group of leading affective neuroscience researchers to present their state-of-the-art findings using an affective neuroscience approach to investigate the spectrum of neuropsychiatric disorders from patients to those at risk. They focus on different aspects of the emotional and social cognitive disturbances which are core features of neuropsychiatric disorders. While progress has been slow over last couple of decades, we are finally beginning to glimpse some of the underlying neural mechanisms of the emotional and social cognitive disturbances in patients and those at risk. With the technological advances in affective neuroscience and neuroimaging presented in this volume, we hope that progress will be much swifter in the coming years such that we can provide better care for patients and those at risk.

Neuroimaging in Developmental Clinical Neuroscience

Neuroimaging in Developmental Clinical Neuroscience Book
Author : Judith M. Rumsey,Monique Ernst
Publisher : Cambridge University Press
Release : 2009-02-19
ISBN : 0521883571
Language : En, Es, Fr & De

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Book Description :

Covers normative structural and functional brain maturation and mechanisms underlying basic developmental processes through neuroimaging.

Developmental Disorders of the Brain

Developmental Disorders of the Brain Book
Author : Nicole J. Rinehart,John L. Bradshaw,Peter G. Enticott
Publisher : Psychology Press
Release : 2016-10-14
ISBN : 1317432657
Language : En, Es, Fr & De

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Book Description :

Developmental Disorders of the Brain: Brain and Behaviour addresses disabilities that occur or have their roots in the early, developmental phase of life which are of utmost concern to parents, siblings, carers and teachers. This text describes the latest clinical and behavioral findings of disorders which largely or entirely involve the frontostriatal (basal ganglia) system including Tourette’s, Obsessive-Compulsive and Attention-Deficit-Hyperactivity disorders, Schizophrenia, Autism, gambling and addiction, depression, and Conduct, Developmental Motor Co-ordination, and language disorders. Examples of disorders involving the frontocerebellar are also described such as Asperger’s disorder, Williams, Fragile X, and Cerebellar Cognitive Affective syndromes, and Friedreich Ataxia. This book also discusses the relevant anatomy, physiology and pathology, and some of the major functions mediated by affected or relevant structures, together with accounts of the latest recording, brain imaging and stimulating techniques related to these kinds of disorders. Covering both frontostriatal and frontocerebellar, systems which control and direct normal behavior, and which can fail with often distressing consequences during development, as well as addressing behavioural, clinical, pathophysiological and technical aspects, this text is vital to understanding, diagnosis and management of developmental disorders of the brain. This text will be of great interest to clinicians, researchers, teachers and parents.

Neuroscience Exploring the Brain Enhanced Edition

Neuroscience  Exploring the Brain  Enhanced Edition Book
Author : Mark Bear,Barry Connors,Michael A. Paradiso
Publisher : Jones & Bartlett Learning
Release : 2020-03-25
ISBN : 1284211282
Language : En, Es, Fr & De

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Book Description :

Acclaimed for its clear, friendly style, excellent illustrations, leading author team, and compelling theme of exploration, Neuroscience: Exploring the Brain, Fourth Edition takes a fresh, contemporary approach to the study of neuroscience, emphasizing the biological basis of behavior. The authors’ passion for the dynamic field of neuroscience is evident on every page, engaging students and helping them master the material. In just a few years, the field of neuroscience has been transformed by exciting new technologies and an explosion of knowledge about the brain. The human genome has been sequenced, sophisticated new methods have been developed for genetic engineering, and new methods have been introduced to enable visualization and stimulation of specific types of nerve cells and connections in the brain. The Fourth Edition has been fully updated to reflect these and other rapid advances in the field, while honoring its commitment to be student-friendly with striking new illustrati

The Oxford Handbook of Clinical Child and Adolescent Psychology

The Oxford Handbook of Clinical Child and Adolescent Psychology Book
Author : Thomas H. Ollendick,Susan W. White,Bradley A. White
Publisher : Oxford University Press
Release : 2018-11-13
ISBN : 0190669764
Language : En, Es, Fr & De

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Book Description :

At the founding in 1896 of the first psychological clinic dedicated to children and adolescents, the study of the psychological treatment of young people lagged behind that of adults, and the basic psychopathology underlying mental disorders in this population was largely ignored. Since those early days, the field has evolved steadily and, in recent years, exponentially. The Oxford Handbook of Clinical Child and Adolescent Psychology is a state-of-the-science volume providing comprehensive coverage of the psychological problems and disorders of childhood. International in scope and penned by the discipline's most eminent scientists and practitioners, the handbook begins with a section on conceptual and empirical issues, followed by exceptional content on specific psychiatric disorders such as intellectual disability, externalizing and internalizing disorders, communication disorders, schizophrenia and bipolar disorder, personality disorders, and many more. The third section offers chapters on special problems in childhood and adolescence, including divorce, the incarceration of parents, suicide and non-suicidal self-injury, bullying, and medical illness. A fourth section covers delivery of clinical services in diverse settings, such as schools and prisons, and the handbook concludes with several chapters on emerging trends and future directions for the field. Conceptually rich and evidence-based, this handbook is an essential resource for students, practitioners, and researchers, providing a cutting-edge compendium of the latest theoretical and empirical developments by leaders of the discipline.

The Genetics of Neurodevelopmental Disorders

The Genetics of Neurodevelopmental Disorders Book
Author : Kevin J. Mitchell
Publisher : John Wiley & Sons
Release : 2015-07-21
ISBN : 1118524993
Language : En, Es, Fr & De

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Book Description :

Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pathogenic mutations, which are grouped here based on the neurodevelopmental processes impacted. Subsequent chapters consider the use of cellular and animal models to elucidate the cascading consequences of such mutations, from molecular and cellular levels to emergent effects on neural circuits, brain systems and subsequent psychological development. The text concludes by examining the important clinical implications of the recent advances in the field, from recognition of the genetic causes in individual patients to development of new treatments and interventions. A timely synthesis, The Genetics of Neurodevelopmental Disorders is a unique and essential resource for neuroscientists, geneticists, neurologists and psychiatrists and an accessible and up-to-date overview for medical and science students.

Application of Basic Neuroscience to Child Psychiatry

Application of Basic Neuroscience to Child Psychiatry Book
Author : S.I. Deutsch,A. Weizman,R. Weizman
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 146130525X
Language : En, Es, Fr & De

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Book Description :

The idea for this book developed during the course of several discussions among the editors while we were working together as staff scientists in the laboratories of the Clinical Neuro science Branch of the National Institute of Mental Health. It was a happy coincidence that the three of us, child psychiatrists with predominantly clinical interests, selected a collaborative bench research project involving neurotransmitter receptor characterization and regulation. We appreciated the relevance of our work to child psychiatry and wished for a forum to share the excitement we enjoyed in the laboratory with our clinical colleagues. Moreover, it seemed to us that much of the pharmacological research in child psychiatry proceeded on an empirical basis, often without a compelling neurochemical rationale. This could reflect the paucity of neurochemical data that exists in child psychiatry and the very limited understanding of the pathophysiology in most psychiatric disorders that occur in childhood. Also, we bemoaned the fact that there was a virtual absence of meaningful interchange between clinical investigators in child psychiatry and their colleagues in the neurosciences. We believed that an edited book appealing to clinicians and basic scientists could serve as an initial effort to foster interchange between them. The editors wish to emphasize that this book is viewed as only a beginning in the process of interchange that must take place.