Skip to main content

Neuroinflammation

In Order to Read Online or Download Neuroinflammation Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Neuroinflammation and CNS Disorders

Neuroinflammation and CNS Disorders Book
Author : Nicola Woodroofe,Sandra Amor
Publisher : John Wiley & Sons
Release : 2014-04-15
ISBN : 1118406540
Language : En, Es, Fr & De

GET BOOK

Book Description :

The last decade has seen an upsurge of information on the role of immune responses in neurodegenerative disorders. In many of these diseases it is still unclear whether the innate and adaptive responses are pathogenic or play a role in repair, and thus understanding their precise roles is key to controlling these diseases by designing immune-therapeutic approaches. The connection between many neurological diseases is the realisation that the immune and nervous systems are inextricable linked, and that perturbations in this delicate balance are involved in many disorders. This has opened up new avenues for therapeutic approaches to treatment of CNS inflammatory and neurodegenerative disorders. Neuroinflammation and CNS Disorders brings together the very latest information on the interactions between the immune system and central nervous system. The first section of the book highlights the basic concepts in the field whilst the second section, the main body of the book, covers the role of the immune response in specific disorders of the central nervous system. Neuroinflammation and CNS Disorders will provide an invaluable guide for both researchers and clinicians working in this complex and dynamic field.

Mechanisms of Neuroinflammation and Inflammatory Neurodegeneration in Acute Brain Injury

Mechanisms of Neuroinflammation and Inflammatory Neurodegeneration in Acute Brain Injury Book
Author : Arthur Liesz,Christoph Kleinschnitz
Publisher : Frontiers Media SA
Release : 2015-11-13
ISBN : 2889196917
Language : En, Es, Fr & De

GET BOOK

Book Description :

Mechanisms of brain-immune interactions became a cutting-edge topic in systemic neurosciences over the past years. Acute lesions of the brain parenchyma, particularly, induce a profound and highly complex neuroinflammatory reaction with similar mechanistic properties between differing disease paradigms like ischemic stroke, intracerebral hemorrhage (ICH) and traumatic brain injury (TBI). Resident microglial cells sense tissue damage and initiate inflammation, activation of the endothelial brain-immune interface promotes recruitment of systemic immune cells to the brain and systemic humoral immune mediators (e.g. complements and cytokines) enter the brain through the damaged blood-brain barrier. These cellular and humoral constituents of the neuroinflammatory reaction to brain injury contribute substantially to secondary brain damage and neurodegeneration. Diverse inflammatory cascades such as pro-inflammatory cytokine secretion of invading leukocytes and direct cell-cell-contact cytotoxicity between lymphocytes and neurons have been demonstrated to mediate the inflammatory ‘collateral damage’ in models of acute brain injury. Besides mediating neuronal cell loss and degeneration, secondary inflammatory mechanisms also contribute to functional modulation of neurons and the impact of post-lesional neuroinflammation can even be detected on the behavioral level. The contribution of several specific immune cell subpopulations to the complex orchestration of secondary neuroinflammation has been revealed just recently. However, the differential vulnerability of specific neuronal cell types and the molecular mechanisms of inflammatory neurodegeneration are still elusive. Furthermore, we are only on the verge of characterizing the control of long-term recovery and neuronal plasticity after brain damage by inflammatory pathways. Yet, a more detailed but also comprehensive understanding of the multifaceted interaction of these two supersystems is of direct translational relevance. Immunotherapeutic strategies currently shift to the center of translational research in acute CNS lesion since all clinical trials investigating direct neuroprotective therapies failed. To advance our knowledge on brain-immune communications after brain damage an interdisciplinary approach covered by cellular neuroscience as well as neuroimmunology, brain imaging and behavioral sciences is crucial to thoroughly depict the intricate mechanisms.

Neuron Glia Interaction in Neuroinflammation

Neuron Glia Interaction in Neuroinflammation Book
Author : Akio Suzumura,Kazuhiro Ikenaka
Publisher : Springer Science & Business Media
Release : 2013-09-13
ISBN : 1461483131
Language : En, Es, Fr & De

GET BOOK

Book Description :

Accumulation on glia is an active pathological element in many neurological disorders. Gliosis produces neuroinflammation through both neurotrophic and inflammatory means, but the exact mechanism through which this happens remain unclear. It is suspected that damage to neurons activates the growth of glial cells. The proposed book focuses on the interaction between neurons and glia to help elucidate the pathophysiology of neuroinflammation in neurological disorders.​

Neuroinflammation and its Resolution From Molecular Mechanisms to Therapeutic Perspectives

Neuroinflammation and its Resolution  From Molecular Mechanisms to Therapeutic Perspectives Book
Author : Morena Zusso,Stefano Moro,Pietro Giusti,Leanne Stokes
Publisher : Frontiers Media SA
Release : 2020-07-14
ISBN : 2889638545
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Neuroinflammation and its Resolution From Molecular Mechanisms to Therapeutic Perspectives book written by Morena Zusso,Stefano Moro,Pietro Giusti,Leanne Stokes, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neuroinflammation

Neuroinflammation Book
Author : Samuel David
Publisher : John Wiley & Sons
Release : 2015-05-26
ISBN : 1118732820
Language : En, Es, Fr & De

GET BOOK

Book Description :

Neuroinflammation has long been studied in its connection to the development and progression of Multiple Sclerosis. In recent years, the fied has expanded to look at the role of inflammatory processes in a wide range of neurological diseases and cognitive disorders including Alzheimer's Disease, Parkinson's and autism. Researchers have also started to appreciate the beneficial impacts of neuroinflammation in certain diseases. Neuroinflammation in the Central Nervous System looks across the discipline and provides a comprehnsive picture of the field. Neuroinflammation in the Central Nervous System is divided into five sections. The opening section looks at fundamental aspects of neuroinflammation. This is followed by two sections that look at the detrimental and beneficial aspects of inflammation on the brain and nervous system. The final two sections look at emerging research on systemic inflammation and the impact of neuroinflammation on the peripheral nervous system. Providing cross-disciplinary coverage, Neuroinflammation in the Central Nervous System, will be an essential volume for neuroimmulogists, neurobiologists, neurologists and any one interested in the field.

Neuroinflammation

Neuroinflammation Book
Author : Alireza Minagar
Publisher : Academic Press
Release : 2018-07-30
ISBN : 0128117249
Language : En, Es, Fr & De

GET BOOK

Book Description :

Neuroinflammation, Second Edition, discusses the role inflammation plays in neuro-inflammatory diseases. As research in neuroinflammation has dramatically increased in recent years, this new edition covers all of the new developments and findings since the first publication nearly a decade ago. Comprehensive coverage of topics includes chapters on multiple sclerosis, optic neuritis and Susac syndrome. New chapters cover the latest research in Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury, amongst other topics. Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma and meningitis, and it contributes to the generation of pain. Researchers are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage, through tolerance, and to modulation and repair. Comprehensively reviews the latest developments in neuroinflammation and neuro-inflammatory diseases Written for researchers and clinical practitioners in clinical neuroscience, neurology and immunology Includes new chapters on Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury

Neuroinflammation and Neurodegeneration

Neuroinflammation and Neurodegeneration Book
Author : Phillip K. Peterson,Michal Toborek
Publisher : Springer
Release : 2014-07-08
ISBN : 149391071X
Language : En, Es, Fr & De

GET BOOK

Book Description :

State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer’s disease, Parkinson’s disease, stroke, viral encephalitides and substance abuse. In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system. With rare exception, no or inadequate treatment exists for the diseases discussed in this book. An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.

Biomarkers of Neuroinflammation

Biomarkers of Neuroinflammation Book
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Release : 2018-02-16
ISBN : 0309463688
Language : En, Es, Fr & De

GET BOOK

Book Description :

Neuroinflammation is a burgeoning area of interest in academia and biopharma, with a broadly acknowledged role in many central nervous system (CNS) disorders. However, there is little agreement on the pathophysiological mechanisms that underlie the manifestations of neuroinflammation in the CNS compartment and how neuroinflammation operates as a driver and also as a consequence of disease in the brain. Moreover, another unclear area is how to translate increased understanding of the mechanisms that underlie neuroinflammation and its manifestations in the CNS to therapeutics. To address these gaps in understanding mechanisms and how to translate that understanding into therapeutics, the Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop on March 20-21, 2017, bringing together key leaders in the field from industry, academia, and governmental agencies to explore the role and mechanisms of neuroinflammation in a variety of CNS diseases. The workshop also considered strategies to advance the identification and validation of biomarkers of neuroinflammation that could accelerate development of therapies, bringing much-needed treatments to patients with disorders ranging from neuroinflammatory diseases such as multiple sclerosis (MS) to neuropsychiatric disorders such as depression. This publication summarizes the presentations and discussions from the workshop.

Neuroinflammation From Bench to Bedside

Neuroinflammation     From Bench to Bedside Book
Author : H. Kettenmann,G. Burton,U. Moenning
Publisher : Springer Science & Business Media
Release : 2013-03-14
ISBN : 3662050730
Language : En, Es, Fr & De

GET BOOK

Book Description :

Recent work has implicated inflammatory processes in the pathophysiology of a variety of neurodegenerative diseases such as Alzheimer's disease, stroke and multiple sclerosis. In this book leading experts in the field discuss molecular, in vivo and clinical aspects of neuroinflammation. It is hoped, with the wealth of research being conductied in this area, that novel therapeutic targets will be identified which will allow successful therapeutic intervention in a variety of neurodegenerative diseases.

A Role for Neuroinflammation and GST mediated Detoxification in Parkinson s Disease

A Role for Neuroinflammation and GST mediated Detoxification in Parkinson s Disease Book
Author : Angelika D. Wahner
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download A Role for Neuroinflammation and GST mediated Detoxification in Parkinson s Disease book written by Angelika D. Wahner, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neuroinflammation

Neuroinflammation Book
Author : Paul L. Wood
Publisher : Springer Science & Business Media
Release : 2002-12-18
ISBN : 159259297X
Language : En, Es, Fr & De

GET BOOK

Book Description :

In this thoroughly updated and revised edition of his much praised book, Paul L. Wood and a panel of leading researchers capture these new developments in a masterful synthesis of what is known today about the inflammatory mediators and cells involved in neurodegenerative diseases. This second edition contains extensive updates on the mediators produced by microglia and their role in neuroinflammatory-induced neuronal lysis. There is also increased coverage of the animal models used in the study of neuroinflammatory mechanisms, of the new imaging methods that allow the noninvasive evaluation of microglial activation in human neurodegernerative disorders, and of the role of neuroinflammation in amyloid-dependent neuronal lysis.

Neuroinflammation and Cognition

Neuroinflammation and Cognition Book
Author : Ashok Kumar,Brandi K Ormerod,Yogesh Dwivedi,Jakob W Streit
Publisher : Frontiers Media SA
Release : 2019-03-22
ISBN : 2889457605
Language : En, Es, Fr & De

GET BOOK

Book Description :

Aging is one of the major risk factors for the onset and progression of various neurodegenerative diseases. Neuroinflammation is a common feature of virtually every central nervous system disease, and is acknowledged as a likely mediator of cognitive impairments. Systemic inflammation levels are augmented with advanced age and neurodegeneration. The influence of age on neuroinflammatory responses including glial activation, increased production of proinflammatory cytokines, and aberrant neuronal signaling could magnify the deterioration of the central nervous system microenvironment in disease, and may contribute to enhanced cognitive impairment. This eBook is a collection of highly informative original research articles, providing comprehensive aspect of neuroinflammation and possible therapeutic interventions in rescuing cognitive impairments.

Mechanisms of Neuroinflammation

Mechanisms of Neuroinflammation Book
Author : Gonzalo Emiliano Aranda Abreu
Publisher : BoD – Books on Demand
Release : 2017-08-23
ISBN : 9535134515
Language : En, Es, Fr & De

GET BOOK

Book Description :

"Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.

Linking Neuroinflammation and Glial Phenotypic Changes in Neurological Diseases

Linking Neuroinflammation and Glial Phenotypic Changes in Neurological Diseases Book
Author : Yu Tang,Xuping Li,Xiaobo Mao
Publisher : Frontiers Media SA
Release : 2020-01-15
ISBN : 2889634108
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Linking Neuroinflammation and Glial Phenotypic Changes in Neurological Diseases book written by Yu Tang,Xuping Li,Xiaobo Mao, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neuroinflammation and Behaviour

Neuroinflammation and Behaviour Book
Author : Luba Sominsky,Adam K. Walker,Deborah M. Hodgson
Publisher : Frontiers Media SA
Release : 2015-07-21
ISBN : 288919602X
Language : En, Es, Fr & De

GET BOOK

Book Description :

The brain and immune system are involved in an intricate network of bidirectional communication. This relationship is vital for optimal physiological and psychological development and functioning but can also result in unwanted outcomes. In particular, this interaction plays an important role in cognition, mood and behaviour. Neuroinflammation is known to contribute to neurological and affective disorders including impaired learning and memory, depressive, anxiety and schizoaffective symptoms, as well as pain. The development of these conditions often occurs on the backdrop of pre-existing physical illnesses which give rise to increased activation of the immune system, such as cancer, obesity, infection and autoimmune disorders. Similarly, psychological states can alter regulation of the immune system. This has been most extensively studied in the context of stress and immune function. Understanding the underlying mechanisms that lead to the onset of inflammation-induced neuropathology and stress-induced immune suppression will contribute to the development of novel and effective treatment strategies for both the disease and its neurological side effects. In this research topic we explored the relationship between the immune system and the brain throughout life. We include both original research and review papers from animal, clinical and molecular perspectives.

Neuroinflammation Latest Findings

Neuroinflammation  Latest Findings Book
Author : Alfred Galswells
Publisher : Unknown
Release : 2019-06-07
ISBN : 9781632416810
Language : En, Es, Fr & De

GET BOOK

Book Description :

Neuroinflammation refers to the inflammation of the nervous tissue, triggered due to traumatic brain injury, infection, autoimmunity or toxic metabolites. The central nervous system exhibits inflammation due to the activation of microglia. The immune response of the peripheral nervous system is through the expression of major histocompatibility complex molecules. Such an immune response though defensive in nature can present itself as a risk of toxicity and widespread inflammation. There is an association of neuroinflammation and neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and multiple sclerosis. There is thus clinical interest in the strategy of inflammation reduction to reverse neurodegeneration. This book discusses the fundamentals as well as modern approaches in the study of neuroinflammation. The topics included in this book on neuroinflammation are of utmost significance and bound to provide incredible insights to readers. It is an essential guide for both academicians and those who wish to pursue this discipline further.

Neuroinflammation in Neuronal Death and Repair

Neuroinflammation in Neuronal Death and Repair Book
Author : Giacinto Bagetta,M. Tiziana Corasaniti,Stuart A. Lipton
Publisher : Academic Press
Release : 2007
ISBN : 0123739896
Language : En, Es, Fr & De

GET BOOK

Book Description :

A current review of the mechanisms of neuroinflammation and their role in neurodegenerative disorders.

Clinical Progress in Neuroinflammation

Clinical Progress in Neuroinflammation Book
Author : Charlie Romero
Publisher : Unknown
Release : 2020-09-15
ISBN : 9781632429001
Language : En, Es, Fr & De

GET BOOK

Book Description :

The inflammation of the nervous tissue is termed as neuroinflammation. It is generally regarded as a chronic inflammation. It is initiated as a response to infection, aging, toxic metabolites, traumatic brain injury, spinal cord injury or autoimmunity. Microglia are activated in response to such stimuli in the central nervous system. The class of proteins called cytokines regulate inflammation, cell signaling and other cell processes such as cell growth and survival. Neuroinflammation is strongly associated with several neurodegenerative diseases, such as Alzheimer's disease, multiple sclerosis and Parkinson's disease. Drug therapy and exercise are some potential treatment strategies for the management of neuroinflammation. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in neuroinflammation. It presents this complex subject in the most comprehensible and easy to understand language. This book, with its detailed analyses and data, will prove immensely beneficial to professionals and students involved in neurology at various levels.

Neuroinflammation

Neuroinflammation Book
Author : Alireza Minagar
Publisher : Elsevier
Release : 2010-12-17
ISBN : 9780123849144
Language : En, Es, Fr & De

GET BOOK

Book Description :

Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair. This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome. Comprehensive review of the latest developments in neuroinflammation Includes contributions from leading authorities

Neuroinflammation

Neuroinflammation Book
Author : Paul L. Wood
Publisher : Springer Science & Business Media
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

In this thoroughly updated and revised edition of his much praised book, Paul L. Wood and a panel of leading researchers capture these new developments in a masterful synthesis of what is known today about the inflammatory mediators and cells involved in neurodegenerative diseases. This second edition contains extensive updates on the mediators produced by microglia and their role in neuroinflammatory-induced neuronal lysis. There is also increased coverage of the animal models used in the study of neuroinflammatory mechanisms, of the new imaging methods that allow the noninvasive evaluation of microglial activation in human neurodegernerative disorders, and of the role of neuroinflammation in amyloid-dependent neuronal lysis.