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Neuroimaging In Parkinsons Disease And Related Disorders

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Imaging in Movement Disorders

Imaging in Movement Disorders Book
Author : Anonim
Publisher : Academic Press
Release : 2018-10-15
ISBN : 9780128154182
Language : En, Es, Fr & De

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Book Description :

Imaging Methodology and Applications in Parkinson's Disease, Volume 141, provides an up-to-date and comprehensive textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools has played a pivotal role in expanding our understanding of disease etiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis, and in the identification of novel targets for therapeutic intervention. This book brings together lessons learned from neuroimaging tools in movement disorders, including chapters on Advances in PET Methodology, Advances in MRI Methodology, Advances in SPECT Methodology, Hybrid PET/MRI Methodology, and more. Provides an up-to-date and comprehensive textbook addressing all aspects of neuroimaging in movement disorders Offers a complete review of advances in core imaging methodology and the application of neuroimaging tools Represents an indispensable educational and research reference of value to all movement disorder specialists, physicians, researchers and students

Imaging in Movement Disorders Imaging in Atypical Parkinsonism and Familial Movement Disorders

Imaging in Movement Disorders  Imaging in Atypical Parkinsonism and Familial Movement Disorders Book
Author : Anonim
Publisher : Academic Press
Release : 2018-11-05
ISBN : 0128151420
Language : En, Es, Fr & De

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Book Description :

Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders, Volume 142, addresses the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools have played a pivotal role in expanding our understanding of disease aetiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis and in the identification of novel targets for therapeutic intervention. This updated volume covers PET Molecular Imaging in Atypical Parkinsonism, SPECT Molecular Imaging in Atypical Parkinsonism, Structural MRI in Atypical Parkinsonism, Functional MRI in Atypical Parkinsonism, and more. Offers a complete review of the applications of neuroimaging tools in Atypical Parkinsonism, familial Parkinson’s disease and Huntington’s disease Discusses the role of neuroimaging modalities, including SPECT, PET, and structural and functional MRI Includes sections on potential clinical applications and future directions

Imaging in Movement Disorders Imaging Applications in Non Parkinsonian and Other Movement Disorders

Imaging in Movement Disorders  Imaging Applications in Non Parkinsonian and Other Movement Disorders Book
Author : Marios Politis
Publisher : Academic Press
Release : 2018-11-21
ISBN : 0128154217
Language : En, Es, Fr & De

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Book Description :

Imaging in Movement Disorders: Imaging in Other Movement Disorders and Dementia, Volume 143 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including idiopathic and sporadic forms of Parkinson’s disease, Huntington’s disease, Atypical Parkinsonism, Dystonia, Essential Tremor, and more. Specific chapters cover Neuroimaging Applications in Dystonia, Neuroimaging Applications in Essential Tremor, Neuroimaging applications in Restless Leg Syndrome, Neuroimaging Application in Tourette's Syndrome and TIC Disorders, Neuroimaging Applications in Functional Movement Disorders, and Neuroimaging Applications in Cerebellar Disorders. Addition sections cover Molecular Imaging of Parkinson's Disease Cognitive Impairment, Structural MRI in Parkinson's Disease Cognitive Impairment, Functional MRI in Parkinson's Disease Cognitive Impairment, Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional MRI of Dementia with Lewy Bodies, Transcranial Sonography in Movement Disorders, Imaging transplantation in Movement Disorders, Hybrid PET-MRI Applications in Movement Disorders, amongst other topics. Offers a complete review of the application of neuroimaging tools in Dystonia, Essential Tremor, Restless Leg Syndrome, Tourette’s syndrome, and Tic and Movement Disorders Covers the role of neuroimaging research in movement disorder dementias Presents the importance of imaging techniques as biomarkers of disease progression and treatment response in therapeutic trials

Imaging in Movement Disorders Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder

Imaging in Movement Disorders  Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder Book
Author : Anonim
Publisher : Academic Press
Release : 2019-01-23
ISBN : 0128187719
Language : En, Es, Fr & De

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Book Description :

Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder, Volume 144 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including chapters on Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional Magnetic Resonance Imaging of Dementia with Lewy Bodies, Network Imaging in Parkinsonian and Other Movement Disorders: Network Dysfunction and Clinical Correlates, Neuroimaging of Rapid Eye Movement Sleep Behavior Disorder, Hybrid PET-MRI Applications in Movement Disorders, and more. Covers the role of neuroimaging research in movement disorder dementias Presents the importance of imaging techniques as biomarkers of disease progression and treatment response in therapeutic trials

Neuroimaging of Movement Disorders

Neuroimaging of Movement Disorders Book
Author : Fatta B. Nahab,Noriaki Hattori
Publisher : Springer Science & Business Media
Release : 2013-06-03
ISBN : 1627034714
Language : En, Es, Fr & De

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Book Description :

In the diagnosis and treatment of movement disorders, the use of neuroimaging has expanded widely and has been an exciting, important modality for unlocking the causes of abnormal motor control. With ever improving machinery, data collection techniques and analysis methods, researchers are now being presented with an exponentially increasing amount of data that they must wade through and interpret in the context of existing knowledge about movement disorders. In Neuroimaging in Movement Disorders, the editors have produced a gold-standard resource that brings together an impressive international group of authorities in their respective fields to outline the current state of knowledge. Controversies, such as conflicting findings and methodological limitations, are covered and provide the reader with a comprehensive yet pragmatic understanding of the state of science. The chapters offer both comprehensive reviews of various neuroimaging methods and also more in-depth summaries of the contributions made by neuroimaging in individual movement disorders. Although many of the neuroimaging methods that are discussed have not been routinely used in clinical practice, the authors skillfully provide the reader with adequate detail to understand the requirements for using these methods and in some cases even the starting knowledge to begin local implementation. Neuroimaging in Movement Disorders is an indispensable reference that will be of value to all physicians and researchers involved in the care of patients with movement disorders.

Metal Related Neurodegenerative Disease

Metal Related Neurodegenerative Disease Book
Author : Anonim
Publisher : Academic Press
Release : 2013-11-07
ISBN : 0124105351
Language : En, Es, Fr & De

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Book Description :

This issue reviews the role of metals in neurodegenerative diseases; including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented. This volume of International Review of Neurobiology brings together cutting-edge research on metal related neurodegenerative disease It reviews the role of metals in neurodegenerative diseases, including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders An update on advances in neuroimaging and pathology of metal related disease is also presented

Clinical and Functional Neuroimaging Studies on Impulse Control Disorders and Related Behaviours in Parkinson s Disease

Clinical and Functional Neuroimaging Studies on Impulse Control Disorders and Related Behaviours in Parkinson s Disease Book
Author : Kit Wu
Publisher : Unknown
Release : 2014
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Clinical and Functional Neuroimaging Studies on Impulse Control Disorders and Related Behaviours in Parkinson s Disease book written by Kit Wu, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Degenerative Disorders of the Brain

Degenerative Disorders of the Brain Book
Author : Darren R. Hocking,John L. Bradshaw,Joanne Fielding
Publisher : Routledge
Release : 2019-04-05
ISBN : 135120890X
Language : En, Es, Fr & De

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Book Description :

Covering a wide range of diverse age-related disorders, Degenerative Disorders of the Brain addresses disabilities that occur or have their roots in the later stages of life. The book brings together an internationally recognised group of contributors to discuss frontostriatal, fronto-cerebellar and other major brain systems and structures which control and direct normal behaviour, and which can fail during the aging process, as well as addressing behavioural, clinical, pathophysiological and technical aspects. Discussing the latest clinical and behavioural findings of disorders which are largely, though not necessarily entirely, age related, including Alzheimer’s disease and other dementias, Parkinson’s disease and related disorders, and Huntington’s disease, the book covers information vital to the understanding, diagnosis, and management of degenerative disorders of the brain. It also considers the role of epigenetics, neural plasticity, and environmental enrichment in neurodegenerative disorders alongside the role of ground-breaking intervention methods, including transcranial magnetic stimulation and deep brain stimulation. Degenerative Disorders of the Brain will be of great interest to, and use for, clinicians, researchers, students, lecturers, and affected individuals and their relatives.

Clinical Neuropsychology and Cognitive Neurology of Parkinson s Disease and Other Movement Disorders

Clinical Neuropsychology and Cognitive Neurology of Parkinson s Disease and Other Movement Disorders Book
Author : Alexander I. Troster
Publisher : Oxford University Press
Release : 2014-10-09
ISBN : 0199977593
Language : En, Es, Fr & De

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Book Description :

The book provides an up-to-date account of the neuropsychological, cognitive-neurological, and neuropsychiatric aspects of movement disorders. The past ten years have seen an explosion of research covering non-motor aspects of Parkinson's disease and, more recently, movement disorders such as essential tremor, dystonia, corticobasal syndrome, progressive supranuclear palsy, and multiple system atrophy. It is often these neurobehavioral features that become troubling to the patient: they are sometimes difficult to recognize and treat, are associated with diminished patient and caregiver quality of life, and may hasten disease progression, loss of independence, and institutionalization. This book discusses the most recent diagnostic and treatment guidelines for such cognitive and psychiatric conditions in Parkinson's disease and other movement disorders, while providing practical tips and strategies for general assessment. The rapid accumulation of research in this field makes it increasingly difficult for one or two people to author a comprehensive text in an expert manner. The world-class team assembled for this volume succeeds in covering widely diverse areas such as the pathology, neuroimaging, assessment, and treatment of an ever-growing set of neurobehavioral features of movement disorders -- cognitive impairment and dementia, depression, apathy, anxiety, psychosis, and impulse control disorders. The text also surveys fundamental knowledge about basal ganglia function and dysfunction, assessment and evaluation techniques applicable to a range of movement disorders, and quality of life issues more broadly.

Neuroimaging in Dementia

Neuroimaging in Dementia Book
Author : Frederik Barkhof,Nick C. Fox,António J. Bastos-Leite,Philip Scheltens
Publisher : Springer Science & Business Media
Release : 2011-02-11
ISBN : 9783642008184
Language : En, Es, Fr & De

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Book Description :

This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.

Therapeutics of Parkinson s Disease and Other Movement Disorders

Therapeutics of Parkinson s Disease and Other Movement Disorders Book
Author : Mark Hallett,Werner Poewe
Publisher : John Wiley & Sons
Release : 2008-10-13
ISBN : 047071400X
Language : En, Es, Fr & De

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Book Description :

Provides a comprehensive update on therapies for Parkinson’s disease and other movement disorders Describes the basic mechanisms of neurodegeneration, pharmacologic interventions for motor and non-motor symptoms, and surgical management Features summary tables and algorithms that serve as a quick reference guide for practical treatment decisions The expert guidance of recognised authorities will enable readers of this book to plan their patients’ care with greater confidence

Parkinson s Disease and Related Disorders

Parkinson s Disease and Related Disorders Book
Author : Peter Riederer,Heinz Reichmann,Moussa B. H. Youdim,Manfred Gerlach
Publisher : Springer Science & Business Media
Release : 2006-11-23
ISBN : 3211452958
Language : En, Es, Fr & De

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Book Description :

This book gives a comprehensive overview on current clinical and basic research issues related to Parkinson’s disease and its related disorders. The book is the result of the 16th International Congress of Parkinson’s Disease and Related disorders congress 2005. Its contents are suitable for neurologists, psychiatrists, neurosurgeons, basic researchers, geneticians and patients as well as their relatives.

Diagnostics and Rehabilitation of Parkinson s Disease

Diagnostics and Rehabilitation of Parkinson s Disease Book
Author : Juliana Dushanova
Publisher : BoD – Books on Demand
Release : 2011-12-07
ISBN : 9533077913
Language : En, Es, Fr & De

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Book Description :

Diagnostics and Rehabilitation of Parkinson's Disease presents the most current information pertaining to news-making topics relating to this disease, including etiology, early biomarkers for the diagnostics, novel methods to evaluate symptoms, research, multidisciplinary rehabilitation, new applications of brain imaging and invasive methods to the study of Parkinson's disease. Researchers have only recently begun to focus on the non-motor symptoms of Parkinson's disease, which are poorly recognized and inadequately treated by clinicians. The non-motor symptoms of Parkinson's disease have a significant impact on patient quality of life and mortality and include cognitive impairments, autonomic, gastrointestinal, and sensory symptoms. In-depth discussion of the use of imaging tools to study disease mechanisms is also provided, with emphasis on the abnormal network organization in parkinsonism. Deep brain stimulation management is a paradigm-shifting therapy for Parkinson's disease, essential tremor, and dystonia. In the recent years, new approaches of early diagnostics, training programmes and treatments have vastly improved the lives of people with Parkinson's disease, substantially reducing symptoms and significantly delaying disability. Written by leading scientists on movement and neurological disorders, this comprehensive book should appeal to a multidisciplinary audience and help people cope with medical, emotional, and practical challenges.

Neuroimaging Biomarkeurs of Structural and Functional Connectivity in Parkinson s Disease

Neuroimaging Biomarkeurs of Structural and Functional Connectivity in Parkinson s Disease Book
Author : Michael Sharman
Publisher : Unknown
Release : 2011
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Parkinson's disease (PD) is a debilitating neurodegenerative disorder involving progressive motor dysfunction, most commonly affecting elderly individuals. A hallmark of disease pathology is a loss of dopaminergic neurons in the substantia nigra and their terminals in the striatum. Neurodegeneration is thought to lead to a destabiliation of the normal signalling that occurs between these, and other cortical and subcortical brain regions. An important challenge for neuroscience lies in differentiating PD neuropathology from similar disorders, as well as those impairments that occur as part of normal aging. The purpose of this thesis was to apply neuroimaging, specifically magnetic resonance imaging (MRI), to identify and evaluate biomarkers of PD. Biomarkers are objective measures of biological state that can be used to quantify a disease, including the symptoms associated with its appearance and progression. Three standalone studies formed the basis of this work. In the first study, outliers in diffusion weighted MRI (DW-MRI) were probed using simulations and real data analyses, to understand their impact on candidate biomarker metrics. Metrics were found to be highly sensitive to error, and data correction was recommended to minimise bias in further analyses. A q-space interpolation method was proposed for identifying and correcting corruptionaffected data, and a decision support system outlined with which to treat this data. In the second study, candidate biomarkers in DW-MRI and resting state functional MRI (rsfMRI) were evaluated to determine their performance as metrics of structural and functional connectivity. A unique, multimodal paradigm demonstrated that anatomical and functional deficits could be attributed to PD for particular connections relevant to the sensorimotor circuit. In the third study, validation of the candidate biomarkers identified in PD was performed in a group of healthy subjects. Here, the objective was to understand the effects of aging on the same associative, limbic and sensorimotor circuitry connecting cortical and subcortical brain regions. Age-related variations in anatomical connectivity were found to differentially affect certain circuits, and nuances in biomarker metrics were observed for particular brain structures. Interestingly, associative circuit functional connections also appeared strengthened. Overall, this thesis successfully identified and evaluated several new candidate biomarkers for PD, as well as furthered an understanding of brain structure and function as it relates to PD, through the development of new analytical pipelines. In addition, tentative conclusions could be drawn regarding the differentiation of PD dysfunction from brain function in healthy elderly subjects.

Cognitive Rehabilitation and Neuroimaging

Cognitive Rehabilitation and Neuroimaging Book
Author : John DeLuca,Nancy D. Chiaravalloti,Erica Weber
Publisher : Springer Nature
Release : 2020-10-05
ISBN : 3030483827
Language : En, Es, Fr & De

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Book Description :

The purpose of this book is to educate readers regarding the efficacy of cognitive rehabilitation across a variety of neurological conditions, with specific emphasis on rehabilitation-related change detectable via neuroimaging. For ease of reference, this information is divided into separate chapters by neurological condition, since the nature of cognitive impairment and mechanism of rehabilitation may differ across populations. Also included are discussions of the use of neuroimaging in cognitive rehabilitation trials, rigorous design of cognitive rehabilitation trials to have greater scientific impact (e.g., obtaining Class I evidence), and future directions for the field. As such, the book is designed to be useful to both clinicians and researchers involved in the rehabilitation of such conditions so that they can make informed decisions regarding evidence-based treatment to deploy in clinical settings or to further study in research endeavors.

PET CT and PET MRI in Neurology

PET CT and PET MRI in Neurology Book
Author : Andrea Ciarmiello,Luigi Mansi
Publisher : Springer
Release : 2016-05-26
ISBN : 3319316141
Language : En, Es, Fr & De

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Book Description :

Using SWOT analysis, this book examines in detail the strengths and weaknesses of the hybrid modalities PET-CT and PET-MRI for imaging of the central nervous system, comparing their merits and evaluating their advantages over the stand-alone modalities. The aim is to employ a truly systematic approach in order to define the potential clinical benefit of these modalities and to identify shortcomings, opportunities, and threats. Clinical application of the modalities is explored in a range of conditions, including dementia and related disorders, movement disorders, psychiatric disorders, cerebrovascular disease, infection/inflammation, brain tumors, and pediatric neurologic disorders. In addition, the basics of hybrid imaging are addressed, covering physics, instrumentation, data analysis and quantitation, radiopharmaceuticals, and contrast media. PET-CT and PET-MRI in Neurology, written by experts from Europe and the United States, will be essential reading for imaging specialists and of value for neurologists, psychiatrists, neurosurgeons, and pediatricians.

Recent Advances in Parkinsons Disease

Recent Advances in Parkinsons Disease Book
Author : Anonim
Publisher : Elsevier
Release : 2010-10-13
ISBN : 9780444537515
Language : En, Es, Fr & De

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Book Description :

This second volume follows on from Part I by reviewing the variety of animal models of PD current available (from drosophila to rodents to non-human primate species) and their specific contributions to PD research. This is followed by comprehensive coverage of functional neuroimaging studies that explore different pathophysiological questions and evaluate treatment outcome in PD patients. Different areas of experimental therapeutics and outstanding challenges to PD treatment are presented in a concluding group of articles. Complete overview of hot topics and approaches to current PD research, from molecules, to brain circuits, to clinical and therapeutic applications Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Imaging in Parkinson s Disease

Imaging in Parkinson s Disease Book
Author : David Eidelberg
Publisher : Oxford University Press
Release : 2011-08-30
ISBN : 0199875146
Language : En, Es, Fr & De

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Book Description :

Imaging in Parkinson's Disease provides up-to-date information concerning new applications of brain imaging to the study of Parkinson's disease. Written by experts in the field, the book focuses on structural and functional imaging methodologies that have recently been applied to study the natural history of Parkinson's disease, with emphasis on the development of the major motor manifestations of the illness as well as cognitive impairment and dementia.

The Neuroimaging of Brain Diseases

The Neuroimaging of Brain Diseases Book
Author : Christophe Habas
Publisher : Springer
Release : 2018-06-15
ISBN : 3319789260
Language : En, Es, Fr & De

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Book Description :

Notable experts in the field of neuroimaging provide comprehensive overviews of advances in functional and structural aspects of both common and uncommon brain disorders. Functional imaging is evolving quickly but researchers and clinicians do not always have a strong understanding of the fundamental basis of the imaging techniques that they use. By focusing on both structure and function this book will provide a strong foundation for emerging developments in the field.

Parkinson s Pocketcard Set

Parkinson s Pocketcard Set Book
Author : M.D. Jost,S. v. Stuckrad-Barre,M.D. Reichmann,M.D. Stuckrad-Barre
Publisher : Borm Bruckmeier Pub Llc
Release : 2012-04-01
ISBN : 9781591034858
Language : En, Es, Fr & De

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Book Description :

The Parkinson pocketcard Set provides essential information on topics related to Parkinson's disease including clinical manifestations, workup and diagnostic criterion, differential diagnosis, staging and treatment. The card contains concise tables and classifications, making it a valuable resource during patient evaluation, on hospital rounds, or as a medical reference. Additional information includes: - Diagnostic criteria for Parkinson's disease (PD) - Movement disorders mimicking PD - Features differentiating PD from other movement disorders - Synopsis of neuroimaging methods - Complications of disease progression - Therapy of progressive Parkinson's disease For physicians, residents, nurses, students and all other healthcare professionals.