Skip to main content

Neurodegenerative Diseases

In Order to Read Online or Download Neurodegenerative Diseases Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Neurodegenerative Diseases

Neurodegenerative Diseases Book
Author : Daniela Galimberti,Elio Scarpini
Publisher : Springer Science & Business
Release : 2014-04-23
ISBN : 144716380X
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic research into biomarkers for early diagnosis. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.

Animal Models of Neurological Disease I

Animal Models of Neurological Disease  I Book
Author : Alan A. Boulton,Glen B. Baker,Roger F. Butterworth
Publisher : Humana Press
Release : 2013-08-18
ISBN : 9781489940223
Language : En, Es, Fr & De

GET BOOK

Book Description :

to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neu- psychiatric disorders. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general preface to these volumes in order to indicate why we think further research using animals is necessary and why animal models of psychi- ric and neurologic disorders, in particular, are so important. We recognize that animals should only be used when suitable alternatives are not available. We think it self-e- dent, however, that humans can only be experimented upon in severely proscribed circumstances and alternative pro- dures using cell or tissue culture are inadequate in any models requiring assessments of behavioral change or of complex in vivo processes. However, when the distress, discomfort, or pain to the animals outweighs the anticipated gains for human welfare, then the research is not ethical and should not be carried out.

Imaging in Neurodegenerative Disorders

Imaging in Neurodegenerative Disorders Book
Author : Luca Saba
Publisher : Oxford University Press, USA
Release : 2014-12-11
ISBN : 0199671613
Language : En, Es, Fr & De

GET BOOK

Book Description :

Diagnosing neurodegenerative diseases can prove particularly intimidating to clinicians, because many times the diagnosis cannot be critically "confirmed" by a simple test. New imaging modalities have advanced to the point of high resolution, morphological, metabolic and functional analysis. Computed tomography, magnetic resonance, nuclear medicine and molecular imaging have recently emerged as outstanding non-invasive techniques for the study of theneurodegenerative disorders. Imaging in Neurodegenerative Disorders covers all the imaging techniques and new exciting methods like new tracers, biomarker, metabolomic and gene-arrayprofiling, potential for applying such techniques clinically, and offers present and future applications as applied to the neurodegenerative disorders with the most world renowned scientists in these fields. The key concepts of pharmacology as well as metabolomic are also covered, making this book an invaluable resource for researchers, clinicians, and trainees in neuroscience, neurology, psychiatry, and radiology.

Neurodegenerative Diseases

Neurodegenerative Diseases Book
Author : M. Flint Beal,Anthony E. Lang,Albert C. Ludolph
Publisher : Cambridge University Press
Release : 2005-06-02
ISBN : 9781139443456
Language : En, Es, Fr & De

GET BOOK

Book Description :

Neurodegenerative diseases are major contributors to disability and disease, with Alzheimer's and Parkinson's diseases the most prevalent. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts in the field internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. The dementias, prion diseases, Parkinson's disease and atypical parkinsonisms, neurodegenerative ataxias, motor neuron diseases, degenerative diseases with chorea, iron and copper disorders, and mitochondrial diseases, are all methodically presented and discussed, with extensive illustrations. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.

Neurodegenerative Diseases

Neurodegenerative Diseases Book
Author : Donald Brian Calne
Publisher : Saunders
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Here is a comprehensive book dedicated to normal neural aging and neurodegenerative disorders. The first section of the text discusses topics relevant to the basic science of neurodegenerative disease such as organic and inorganic neurotoxins, virus and neurodegeneration, lewy bodies, and neurofibrillary tangle. Dr. Calne and over 75 international experts next focus on specific disease entities such as Parkinson's, ALS, Alzheimers, and a host of other common and rare diseases and present the pathology, clinical features, natural history and treatment of each. In addition, emphasis is placed on the practical problems of diagnosis and treatment.

Brain Fables

Brain Fables Book
Author : Alberto Espay,Benjamin Stecher
Publisher : Cambridge University Press
Release : 2020-06-30
ISBN : 1108744621
Language : En, Es, Fr & De

GET BOOK

Book Description :

"In Sapiens, Yuval Noah Harari argues that humankind's greatest invention is our ability to create and believe fictions. While all other animals communicate realities with which they interact, humans create a separate layer of subjective, interpretative realities. The fiction most universally embraced today is money. "Dollar bills have absolutely no value except in our collective imagination, but everybody believes in the dollar bill," says Harari. Harari goes on to state that humans have been living in a dual reality. "On the one hand, the objective reality of rivers, trees, and lions; and on the other hand, the imagined reality of gods, nations, and corporations." In medicine, humans have also created two realities. Clinicians describe what they see, an objective reality, but the medical community then tries to explain and give meaning to what they see, creating a second,"--

Neurodegenerative Diseases

Neurodegenerative Diseases Book
Author : Shamim I. Ahmad
Publisher : Springer Science & Business Media
Release : 2012-03-12
ISBN : 1461406536
Language : En, Es, Fr & De

GET BOOK

Book Description :

The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing ·OH scavenging activities details of which are anticipated to be published in the near future as confirmatory experiments are awaited. It is hoped that the information presented in this book on NDs will stimulate both expert and novice researchers in the field with excellent overviews of the current status of research and pointers to future research goals. Clinicians, nurses as well as families and caregivers should also benefit from the material presented in handling and treating their specialised cases. Also the insights gained should be valuable for further understanding of the diseases at molecular levels and should lead to development of new biomarkers, novel diagnostic tools and more effective therapeutic drugs to treat the clinical problems raised by these devastating diseases.

Neurodegenerative Diseases

Neurodegenerative Diseases Book
Author : G. Jolles,J. M. Stutzmann
Publisher : Academic Press
Release : 1994-11-28
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Over the last few years, the considerable progress made in biochemistry, virology, molecular biology and genetics has revealed some of the intimate mechanisms of the neurodegenerative diseases. The present volume is an attempt to review the latest data in the field to illuminate new avenues for future research. This volume gathers together chapters and discussions on the etiology and pathogenesis of the neurodegenerative diseases. Apoptosis of programmed cell death as well as other genetic implications are discussed; special attention is given to the coexistence and interconnection of genetic and environmental factors. There is extensive coverage of prions responsible for bovine spongiform encephalopathy, Cruetzfeld-Jacob disease and kuru. The various aspects of non-conventional transmissible agents are thoroughly reviewed. Further contributions deal with the role of growth factors as well as of free radicals. Consideration is given to the molecular mechanisms of Alzheimer's disease, in particular the role of tau protein. Finally, several pharmacological models now available, which throw light upon aspects of Parkinson's disease, Huntington's chorea and multiple sclerosis, are examined and discussed. It is hoped that recent scientific advances will lead to the discovery of new drugs to fill the current therapeutic void. There are hopes of an early indication of this in the case of amyotrophic lateral sclerosis.

Animal Biotechnology

Animal Biotechnology Book
Author : Ashish S. Verma,Anchal Singh
Publisher : Academic Press
Release : 2020-07-03
ISBN : 0128117109
Language : En, Es, Fr & De

GET BOOK

Book Description :

Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies

Official Gazette of the United States Patent and Trademark Office

Official Gazette of the United States Patent and Trademark Office Book
Author : Anonim
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Official Gazette of the United States Patent and Trademark Office book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Protective Strategies for Neurodegenerative Diseases

Protective Strategies for Neurodegenerative Diseases Book
Author : Debomoy K. Lahiri
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

The incidence of age-related neurodegenerative diseases can be expected to rise dramatically in the future owing to an aging population. Consequently, finding the means of retarding the progression of such diseases becomes increasingly important. This volume focuses on research findings involving both nutritional and pharmacological strategies for slowing normal brain aging and its pathological variants such as Alzheimer's and Parkinson's diseases. Scientists well recognized for their molecular and mechanistic work in this area have contributed chapters to this volume. New concepts concerning neurodegenerative disease and its mitigation are also included in this volume, which is designed to promote the development of fresh research perspectives and therapeutic possibilities directed toward neuroprotection.

Neurodegenerative Diseases

Neurodegenerative Diseases Book
Author : Jagan A. Pillai
Publisher : Oxford University Press
Release : 2016-11-14
ISBN : 0190233567
Language : En, Es, Fr & De

GET BOOK

Book Description :

As the global population ages the impact of neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are significant forces in shaping human health and quality of life in the 21st century. Insights into understanding these diseases, and knowing how to treat them are major frontiers of scientific research. Neurodegenerative Diseases: Unifying Principles is the result of a conceptual revolution over the last decade in our understanding of neurodegenerative diseases as sharing unifying features. There is an increasing appreciation of the common biological and pathological features across seemingly varied neurodegenerative diseases that entail protein misfolding dysfunction and its consequences over time. Providing an overview of this conceptual change is the main theme for the book. Conventional approach emphasize the differences among neurodegenerative disorders, here Drs. Cummings and Pillai compile the increasingly compelling evidence that these disorders share many features and that insights in one may be rapidly translated into advances in another. The goal is to accelerate understanding by showing linkages among biological, pathological, can clinical aspects of this class of diseases. This collection of 19, inter-related chapters, articulates and broadens our view of the unifying features that initiate and drive disease progression across a variety of neurodegenerative diseases over time. This book will serve as an outstanding sourcebook of insights from experts that have played key roles in this story.

Neurodegeneration

Neurodegeneration Book
Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Release : 2013-12-12
ISBN : 0309285704
Language : En, Es, Fr & De

GET BOOK

Book Description :

Neurodegeneration: Exploring Commonalities Across Diseases is the summary of a workshop hosted by the Institute of Medicine\'s (IOM\'s) Forum on Neuroscience and Nervous System Disorders in Spring 2012 to explore commonalities across neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD). Participants from academia; pharmaceutical and biotechnology industries; government agencies such as the National Institutes of Health and the U.S. Department of Veterans Affairs (VA); patient advocacy groups; and private foundations presented and identified potential opportunities for collaboration across the respective research and development communities. This report identifies and discusses commonalities related to genetic and cellular mechanisms, identifies areas of fundamental science needed to facilitate therapeutics development, and explores areas of potential collaboration among the respective research communities. Neurodegenerative diseases, such as Alzheimer\'s disease, Parkinson\'s disease, ALS, and FTD, are becoming increasingly prevalent in the United States due to an aging population. Implications are grave for quality of life and health care costs. Research on neurodegenerative diseases has expanded greatly over the past four decades. Nevertheless, fundamental questions remain about the biology of these diseases, and further insights into the mechanisms of these diseases would help to inform the development of effective means to prevent and to efficiently treat them. Recent findings have revealed certain commonalities in genetic and cellular mechanisms across neurodegenerative diseases. These findings suggest that it might be valuable - at least in some cases - to change the traditional way of studying these diseases by no longer seeing each as an independent entity, but rather as clinical variants of common cellular and molecular biological defects. This approach could help enhance basic scientific understanding of neurodegenerative disease, and could help with the development of biomarkers and new therapeutics.

Molecular Mechanisms of Neurodegenerative Diseases

Molecular Mechanisms of Neurodegenerative Diseases Book
Author : Marie-Francoise Chesselet
Publisher : Springer Science & Business Media
Release : 2000-10-19
ISBN : 1592590063
Language : En, Es, Fr & De

GET BOOK

Book Description :

With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from different yet complementary points of view. Focusing on Alzheimer's, Parkinson's, and CAG triplet repeat diseases, the authors show how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and may lead to the development of new therapeutics. Topics include the role of Ab toxicity, glial cells, and inflammation in Alzheimer's disease; the formation of abnormal protein fragments across several diseases, the impact of dopamine and mitochondrial dysfunction on neurodegeneration; and the potential of genetics to identify the molecular mechanisms of neurodegenerative diseases. Authoritative and insightful, Molecular Mechanisms of Neurodegenerative Diseases synthesizes the novel ideas and concepts now emerging to create a fresh understanding of neurodegenerative disorders, one that promises to lead to powerful new therapies that prevent, delay the onset, slow the progression, or even cure these cruel diseases.

Neurodegenerative Diseases

Neurodegenerative Diseases Book
Author : Rommy von Bernhardi,Nibaldo C. Inestrosa
Publisher : Nova Publishers
Release : 2008
ISBN : 9781604561678
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book discusses in detail the different hypothesis and experimental evidence regarding the neurobiological mechanisms involved in neurodegenerative pathology, with an emphasis in Alzheimer's and Parkinson's disease. Since there are many hypotheses for neurodegenerative diseases, there is a real need for a comprehensive view, allowing for integration of the different views for the pathogenic mechanisms of the disease.

Hypersomnolence an Issue of Sleep Medicine Clinics E Book

Hypersomnolence  an Issue of Sleep Medicine Clinics  E Book Book
Author : Ahmed BaHamman
Publisher : Elsevier
Release : 2017-08-17
ISBN : 0323545734
Language : En, Es, Fr & De

GET BOOK

Book Description :

This issue of Sleep Medicine Clinics is edited by Dr.Ahmed BaHammam and focuses on Hypersomnia. Article topics include: Hypersomnia: neurobiological basis; Narcolepsy Immunogenetics: Where is the Evidence?; Genetic markers of sleepiness; Autonomic function instabilities in Narcolepsy; Epidemiology of Excessive Daytime Sleepiness; Evaluation of the sleepy patient: differential diagnosis; Subjective and objective assessment of hypersomnia; Sleepiness in Narcolepsy; Idiopathic hypersomnia; Sleep disordered breathing and excessive daytime sleepiness; Drug-induced excessive sleepiness; Kleine-Levin syndrome and recurrent hypersomnia; Behaviorally induced insufficient sleep syndrome: an underestimated cause of hypersomnia; Sleepiness in children; Sleepiness in Adolescents; Sleepiness in the elderly; Depression and Hypersomnia: a complex association; Neurodegenerative diseases and excessive sleepiness; Sleepiness and traffic safety; Pharmacological management of excessive daytime sleepiness; Non-pharmacological management of excessive daytime sleepiness.

The Benefits of Natural Products for Neurodegenerative Diseases

The Benefits of Natural Products for Neurodegenerative Diseases Book
Author : M. Mohamed Essa,Mohammed Akbar,Gilles Guillemin
Publisher : Springer
Release : 2016-09-20
ISBN : 3319283839
Language : En, Es, Fr & De

GET BOOK

Book Description :

Focuses on the effects of natural products and their active components on brain function and neurodegenerative disease prevention. Phytochemicals such as alkaloids, terpenes, flavanoids, isoflavones, saponins etc are known to possess protective activity against many neurological diseases. The molecular mechanisms behind the curative effects rely mainly on the action of phytonutrients on distinct signaling pathways associated with protein folding and neuro-inflammation. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases, disorders, or insults, such as Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, traumatic brain injury, and other neuronal dysfunctions. However, the use of these antioxidants in the management of neurodegenerative conditions has so far been not well understood. This is a comprehensive collection addressing the effects on the brain of natural products and edible items such as reservatrol, curcumin, gingerol, fruits, vegetables, nuts, and marine products.

Neurodegenerative Disorders Loss of Function Through Gain of Function

Neurodegenerative Disorders  Loss of Function Through Gain of Function Book
Author : K. Beyreuther,Y. Christen,C.L. Masters
Publisher : Springer Science & Business Media
Release : 2001-03-13
ISBN : 9783540412182
Language : En, Es, Fr & De

GET BOOK

Book Description :

The main message from this book is that the different protein aggregation processes may all be amenable to a small number of intervention steps based on a common theme of the modulation of production, turnover and deposition of the corresponding disease gene products. The next few years will prove critical in evaluation the possibilities of rational therapeutic strategies towards regaining the loss of function through the amelioration of the abnormal gain of function.

Handbook of Traumatic Brain Injury and Neurodegeneration

Handbook of Traumatic Brain Injury and Neurodegeneration Book
Author : R.J. Castellani
Publisher : IOS Press
Release : 2020-04-24
ISBN : 164368065X
Language : En, Es, Fr & De

GET BOOK

Book Description :

Holbourne’s theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood ‘punch drunk’ syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.

Index Medicus

Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.