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Neurobiology Of Psychiatric Disorders

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Neurobiology of Mental Illness

Neurobiology of Mental Illness Book
Author : Dennis S. Charney,Joseph D. Buxbaum,Pamela Sklar,Eric J. Nestler
Publisher : Oxford University Press
Release : 2013-07-04
ISBN : 0199934959
Language : En, Es, Fr & De

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Book Description :

Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.

Neurobiology of Psychiatric Disorders

Neurobiology of Psychiatric Disorders Book
Author : Thomas E Schlaepfer,Charles B. Nemeroff
Publisher : Elsevier
Release : 2012-07-09
ISBN : 0444520023
Language : En, Es, Fr & De

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Book Description :

This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Neurobiology of Brain Disorders

Neurobiology of Brain Disorders Book
Author : Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland
Publisher : Elsevier
Release : 2014-12-03
ISBN : 0123982804
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Charney Nestler s Neurobiology of Mental Illness

Charney   Nestler s Neurobiology of Mental Illness Book
Author : Dennis S. Charney,Pamela B. Sklar,Eric J. Nestler,Joseph D. Buxbaum
Publisher : Oxford University Press
Release : 2018
ISBN : 019068142X
Language : En, Es, Fr & De

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Book Description :

Preceded by Neurobiology of mental illness / edited by Dennis S. Charney ... [et al.]. 4th ed. 2013.

Neurobiology of Bipolar Disorder

Neurobiology of Bipolar Disorder Book
Author : Joao Luciano de Quevedo,Andre Ferrer Carvalho,Eduard Vieta
Publisher : Academic Press
Release : 2020-11-25
ISBN : 012819183X
Language : En, Es, Fr & De

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Book Description :

The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

Neurobiology of Brain Disorders

Neurobiology of Brain Disorders Book
Author : Michael J. Zigmond,Clayton A. Wiley,Marie-Francoise Chesselet
Publisher : Academic Press
Release : 2022-05-27
ISBN : 0323898254
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders, Second Edition provides basic scientists a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases. Topics include developmental, autoimmune, central, and peripheral neurodegeneration, infectious diseases, and diseases of higher function. Organized by individual disorder, each chapter includes coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. This volume reflects progress in the field since publication of the first edition, with fully updated chapters, and new chapters on isolation, aging, global diseases, vascular diseases, and toxic/metabolic disease. New disorder coverage includes fibromyalgia, chronic fatigue, Restless Legs Syndrome, myasthenia gravis, and more. Links basic, translational and clinical research on disorders of the nervous system Covers a vast array of neurological and psychiatric disorders, including Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson's, Huntington's, Alzheimer's, OCD, PTSD, schizophrenia, depression and pain Features new chapters on the effects of aging and isolation on brain health Expands coverage on disorders, including new chapters on fibromyalgia, chronic fatigue, and restless legs syndrome Features in-text summary points, special feature boxes and research questions

The Neuroscience of Clinical Psychiatry

The Neuroscience of Clinical Psychiatry Book
Author : Edmund S. Higgins,Mark S. George
Publisher : Lippincott Williams & Wilkins
Release : 2012-11-05
ISBN : 1469802007
Language : En, Es, Fr & De

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Book Description :

Bringing the latest breakthroughs in neuroscience to the clinician, this text provides resident and practicing psychiatrists with a comprehensive, clinically relevant overview of the brain mechanisms underlying behavior and mental illness. The book presents an integrated perspective on the structures and workings of the brain, the mechanisms governing behaviors such as pleasure, aggression, and intelligence, and the pathophysiology of mental disorders. More than 200 two-color illustrations clarify key concepts. Questions and answers at the end of each chapter facilitate review and board preparation. Readers will also have online access to the complete, fully searchable text and a quiz bank of over 150 questions at www.neuroscienceofclinicalpsychiatry.com.

Neurobiology of Mental Illness

Neurobiology of Mental Illness Book
Author : Dennis S. Charney,Eric J. Nestler
Publisher : Oxford University Press
Release : 2005-07-21
ISBN : 0195189809
Language : En, Es, Fr & De

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Book Description :

The new edition of this definitive textbook reflects the continuing reintegration of psychiatry into the mainstream of biomedical science. The research tools that are transforming other branches of medicine - epidemiology, genetics, molecular biology, imaging, and medicinal chemistry - are also transforming psychiatry. The field stands poised to make dramatic advances in defining disease pathogenesis, developing diagnostic methods capable of identifying specific and valid disease entities, discovering novel and more effective treatments, and ultimately preventing psychiatric disorders. The Neurobiology of Mental Illness is written by world-renowned experts in basic neuroscience and the pathophysiology and treatment of psychiatric disorders. It begins with a succint overview of the basic neurosciences followed by and evaluation of the tools that are available for the study of mental disorders in humans. The core of the book is a series of consistently organized sections on the major psychiatric disorders that cover their diagnostic classification, molecular genetics, functional neuroanatomy, neurochemistry and pharmacology, neuroimaging, and principles of pharmacotherapy. Chapters are written in a clear style that is easily accessible to practicing psychiatrists, and yet they are detailed enough to interest researchers and academics.For this second edition, every section has been thoroughly updated, and 13 new chapters have been added in areas where significant advances have been made, including functional genomics and animal models of illness; epidemiology; cognitive neuroscience; postmortem investigation of human brain; drug discovery methods for psychiatric disorders; the neurobiology of schizophrenia; animal models of anxiety disorders; neuroimaging studies of anxiety disorders; developmental neurobiology and childhood onset of psychiatric disorders; the neurobiology of mental retardation; the interface between neurological and psychiatric disorders; the neurobiology of circadian rhythms; and the neurobiology of sleep disorders. Both as a textbook and a reference work, Neurobiology of Mental Illness represents a uniquely valuable resource for psychiatrists, neuroscientists, and their students or trainees.

Child and Adolescent Behavioral Health

Child and Adolescent Behavioral Health Book
Author : Edilma L. Yearwood,Geraldine S. Pearson,Jamesetta A. Newland
Publisher : John Wiley & Sons
Release : 2021-02-23
ISBN : 1119487587
Language : En, Es, Fr & De

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Book Description :

Research has shown that a range of adult psychiatric disorders and mental health problems originate at an early age, yet the psychiatric symptoms of an increasing number of children and adolescents are going unrecognized and untreated—there are simply not enough child psychiatric providers to meet this steadily rising demand. It is vital that advanced practice registered nurses (APRNs) and primary care practitioners take active roles in assessing behavioral health presentations and work collaboratively with families and other healthcare professionals to ensure that all children and adolescents receive appropriate treatment. Child and Adolescent Behavioral Health helps APRNs address the mental health needs of this vulnerable population, providing practical guidance on assessment guidelines, intervention and treatment strategies, indications for consultation, collaboration, referral, and more. Now in its second edition, this comprehensive and timely resource has been fully updated to include DSM-5 criteria and the latest guidance on assessing, diagnosing, and treating the most common behavioral health issues facing young people. New and expanded chapters cover topics including eating disorders, bullying and victimization, LGBTQ identity issues, and conducting research with high-risk children and adolescents. Edited and written by a team of accomplished child psychiatric and primary care practitioners, this authoritative volume: Provides state-of-the-art knowledge about specific psychiatric and behavioral health issues in multiple care settings Reviews the clinical manifestation and etiology of behavioral disorders, risk and management issues, and implications for practice, research, and education Offers approaches for interviewing children and adolescents, and strategies for integrating physical and psychiatric screening Discusses special topics such as legal and ethical issues, cultural influences, the needs of immigrant children, and child and adolescent mental health policy Features a new companion website containing clinical case studies to apply concepts from the chapters Designed to specifically address the issues faced by APRNs, Child and Adolescent Behavioral Health is essential reading for nurse practitioners and clinical nurse specialists, particularly those working in family, pediatric, community health, psychiatric, and mental health settings.

Insight and Psychosis

Insight and Psychosis Book
Author : Xavier F. Amador,Anthony S. David
Publisher : Oxford University Press
Release : 2004-07-22
ISBN : 0198525680
Language : En, Es, Fr & De

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Book Description :

The insight a patient shares into their own psychosis is fundamental to their condition - it goes to the heart of what we understand 'madness' to be. Can a person be expected to accept treatment for a condition that they deny they have? Can a person be held responsible for their actions if those actions are inspired by their own unique perceptions and beliefs - beliefs that no-one else shares? The topic of insight in schizophrenia and related disorders has become a major focus of research in psychiatry and psychology. It has important clinical implications in terms of outcome, treatment adherence, competence, and forensic issues. In order to study 'insight' a broad perspective is required. This involves applying knowledge from the cognitive and brain sciences, as well as from philosophy and the social sciences. Insight and Psychosis comprises a series of in-depth, well-referenced, scholarly overviews from each of these perspectives with a strong empirical foundation - including in some cases the presentation of new data and meta-analysis of the published literature. These are integrated and synthesised by the editors, both acknowledged experts in the field. The scope is truly international and spans theoretical perspectives, clinical practice, and consumer views. The book will act as a source for students and researchers interested in pursuing any number of questions and controversies around lack of insight and awareness, and will guide clinical psychologists and psychiatrists who seek a broader view of the many facets of insight that might arise during their day-to-day work.

Catatonia

Catatonia Book
Author : Stanley N. Caroff,Stephan C. Mann,Andrew Francis,Gregory L. Fricchione
Publisher : American Psychiatric Pub
Release : 2007-05-03
ISBN : 1585627127
Language : En, Es, Fr & De

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Book Description :

During the 20th century, catatonia all but dropped off the agenda of mainstream psychiatric research. However, several dedicated research groups, represented in this volume, continued to report original data highlighting catatonia as a relevant and ideal subject for clinical study. This book, which exemplifies the unparalleled breadth of the knowledge gained, will benefit clinicians managing catatonic phenomena as well as researchers interested in pursuing further investigations. This book covers in great detail the psychopathology and neurobiology of catatonia, focusing on the history, epidemiology, etiology, diagnosis and treatment of the disorder. This comprehensive volume Offers a wide representation of the historical and worldwide literature on the many variants of catatonia in a single, well-organized text. Includes work presented by the original investigators, many of whom work outside the United States and have had their previous studies published only in non-English journals. Covers alternative opinions and perspectives on catatonia, contributing novel and illuminating perspectives on the syndrome. Addresses areas of controversy -- including disagreements over treatment and the nosologic status of catatonia -- head-on, in a balanced, evidence-based presentation. Balances practical clinical material with the underlying neurobiology, presenting clinical aspects in the context of history, epidemiology, cross-cultural perspectives, and neurobiological findings and highlighting the richness and intellectual attraction of the study of the disorder. Catatonia is unique in offering a diverse, international group of contributors and such a comprehensive, up-to-date review of the clinical and scientific literature, spanning the breadth of contemporary understanding about the nature, meaning, and importance of the syndrome.

The Neurobiology of Cognition and Behavior

The Neurobiology of Cognition and Behavior Book
Author : John Hart, Jr.
Publisher : Oxford University Press
Release : 2016
ISBN : 0190219033
Language : En, Es, Fr & De

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Book Description :

"Neurobiology of Cognition and Behavior" is one of the initial textbooks of brain mapping in the field of cognitive neuroscience. This well-researched text by a leading expert in the field provides a foundational map of the human brain for cognition and behavior. This comprehensive map of essential human thinking and emotion is based on the explosion in the field of functional neuroimaging studies (fMRI, PET) in the normally functioning human brain. The approach of this text is to confirm the association of these brain regions by verifying that damage to the activated brain area results in a consistent deficit in the cognitive/behavioral operation under investigation. The approach used to form this view of mapping brain and cognition is based on cognitive neuroscience principles of defining dissociable, fine-grained cognitive units and associating these units with brain regions encoding for these units or aspects of the units from both functional imaging and lesion studies. These cognitive-brain relationships are incorporated into clinical syndromes to account for the behavior of these patients after a lesion occurs, with the added feature of presenting patient videos demonstrating the disrupted cognitive behaviors. This comprehensive textbook provides a framework of the basic architecture of cognition in the brain with this combination of activation and lesion study confirmation of the brain-behavior associations. This basic framework is useful for those students studying the interaction of cognitive science and neuroanatomy as well as being relevant to the experienced neuroscientist researcher or clinician.

Neurobiology of Depression

Neurobiology of Depression Book
Author : Francisco Lopez-Munoz,Cecilio Alamo
Publisher : CRC Press
Release : 2011-09-09
ISBN : 143983850X
Language : En, Es, Fr & De

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Book Description :

Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, molecular biology, genomics, psychiatry, psychology, and pharmacology, Neurobiology of Depression discusses the nature of the central nervous system circuits responsible for the modifications of neuronal functioning that lead to depression. The book begins by discussing animal, neurophysiological, and neuropsychological models of depression as well as neural foundations. It explores genetic factors that contribute to depression and describes the effect of monoaminergic systems in the central nervous system. Next, the book profiles the rise of psychopharmacology in the treatment of depression and the research into serotonin and monoamine reuptake inhibitors. It examines the role of the glutamatergic, endocannabinoid, and opioid systems in the pathophysiology of mood disorders, as well as the effect of biological rhythms on the human body. Later chapters review the role of CRF-related ligands, CRF receptors, HPA axis activity, and glucocorticoid receptors in the regulation of the stress response and depression. They also describe cytokine modulation of molecular mechanisms. They examine the role of neuropeptide Y, nitric oxide, beta-arrestins, BDNF, and phosphodiesterases, and discuss the use of tachykinin antagonists in treatment. Finally, they analyze the neurobiological basis for the development of new antidepressant agents. Exploring myriad aspects of a disease that plagues a large percentage of the population worldwide, this volume captures the state of the science of this debilitating disorder, facilitating further research and discovery.

Genomics Circuits and Pathways in Clinical Neuropsychiatry

Genomics  Circuits  and Pathways in Clinical Neuropsychiatry Book
Author : Thomas Lehner,Bruce L. Miller,Matthew W. State
Publisher : Academic Press
Release : 2016-06-07
ISBN : 0128005300
Language : En, Es, Fr & De

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Book Description :

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment

Neurobiology of Depression

Neurobiology of Depression Book
Author : Joao Luciano de Quevedo,Andre Ferrer Carvalho,Carlos A. Zarate
Publisher : Academic Press
Release : 2019-01-03
ISBN : 0128133341
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments, to antidepressants and novel therapeutics Synthesizes discussions on the cellular and molecular mechanisms underlying symptoms with the clinical aspects of depression

The Neurobiology of Schizophrenia

The Neurobiology of Schizophrenia Book
Author : Ted Abel,Thomas Nickl-Jockschat
Publisher : Academic Press
Release : 2016-07-08
ISBN : 0128018771
Language : En, Es, Fr & De

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Book Description :

The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible

The Neurobiology Psychotherapy Pharmacology Intervention Triangle

The Neurobiology Psychotherapy Pharmacology Intervention Triangle Book
Author : João G. Pereira,Jorge Gonçalves,Valeria Bizzari
Publisher : Vernon Press
Release : 2019-05-30
ISBN : 1622734335
Language : En, Es, Fr & De

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Book Description :

This book intends to open the debate between three main aspects of clinical practice: psychotherapy (including psychological and philosophical influences), neurobiology and pharmacology. These three main themes are clinically applied in what we call the “Intervention Triangle”. The book will first focus on epistemologically distinct frameworks and gradually attempt to consider the integration of these three fundamental vertexes of practice. These vertexes are substantially unbalanced in the mental health field, and thus, this book tries to make sense of this phenomenon. Unique in its interdisciplinary and comprehensive view of mental health problems and approaches, this book offers a new perspective on unidisciplinary integration that previous publications have not considered. As an innovative contribution to its field, this volume will be particularly relevant to practitioners working towards integrative frameworks. It will also be of interest to students, clinicians and researchers, in particular, those working in psychology, medicine, psychiatry, philosophy, social work, and pharmacy.

Bipolar Disorder

Bipolar Disorder Book
Author : Lakshmi N. Yatham,Mario Maj
Publisher : John Wiley & Sons
Release : 2011-06-28
ISBN : 1119956226
Language : En, Es, Fr & De

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Book Description :

Bipolar disorder is the most complex psychiatric disorder with different types of mood episodes, subtypes, varied course, and significant co-morbidity. Not surprisingly, this complexity poses unique challenges to clinicians for optimal management of those with bipolar disorder. There has been an explosion of research into the causes and treatment of this condition over the past two decades. It is a daunting task for a practising clinician to make sense of this research and to remain up to date with progress in the understanding of the neurobiology and treatment of bipolar disorder. This book synthesizes and translates the vast array of research knowledge into information that is clinically relevant and meaningful for a clinician. The book provides a comprehensive, yet focused, reference work on bipolar disorder for both trainees and practising psychiatrists. The two editors are leaders in the field who have published extensively on bipolar disorder. They have assembled a team of experts from around the world: in many instances, chapters are co-authored by people from different continents, bringing a truly international perspective to this important topic. The book covers the basic science of the pathology underlying bipolar disorder but addresses the clinical aspects of the disease throughout. The book comprises four sections: Descriptive Aspects—issues ranging from how the concept of bipolar disorder has evolved over the years to new information about neurocognitive impairment, creativity and economic productivity, and to discussion of the deliberations of the DSM-V committee on changes in diagnostic categories and criteria. Biology—the contribution of genes to this disorder, changes in circadian rhythms, what we know about brain changes and the role of oxidative stress. Biological Treatment and Psychosocial Treatment— all the latest information about pharmacological and psychological treatments and the optimal management of this condition. If you want to provide state-of-the-art care to your bipolar patients, be sure to consult this authoritative reference.

The Bipolar Book

The Bipolar Book Book
Author : Aysegül Yildiz,Pedro Ruiz,Charles B. Nemeroff
Publisher : Oxford University Press, USA
Release : 2015
ISBN : 0199300534
Language : En, Es, Fr & De

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Book Description :

The Bipolar Book covers not only clinical and pathophysiological matters, but also technical aspects of the evidence accumulation for treatment of bipolar disorder.

The Self in Neuroscience and Psychiatry

The Self in Neuroscience and Psychiatry Book
Author : Tilo Kircher,Anthony S. David,Anthony David
Publisher : Cambridge University Press
Release : 2003-08-07
ISBN : 9780521533508
Language : En, Es, Fr & De

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Book Description :

In recent years the clinical and cognitive sciences and neuroscience have contributed important insights to understanding the self. The neuroscientific study of the self and self-consciousness is in its infancy in terms of established models, available data and even vocabulary. However, there are neuropsychiatric conditions, such as schizophrenia, in which the self becomes disordered and this aspect can be studied against healthy controls through experiment, building cognitive models of how the mind works, and imaging brain states. In this 2003 book, the first to address the scientific contribution to an understanding of the self, an eminent, international team focuses on current models of self-consciousness from the neurosciences and psychiatry. These are set against introductory essays describing the philosophical, historical and psychological approaches, making this a uniquely inclusive overview. It will appeal to a wide audience of scientists, clinicians and scholars concerned with the phenomenology and psychopathology of the self.