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Neurobiology Of Brain Disorders

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Neurobiology of Brain Disorders

Neurobiology of Brain Disorders Book
Author : Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland
Publisher : Elsevier
Release : 2014-12-03
ISBN : 0123982804
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Neurobiology of Mental Illness

Neurobiology of Mental Illness Book
Author : Dennis S. Charney,Eric J. Nestler,Pamela Sklar,Joseph D. Buxbaum
Publisher : Oxford University Press
Release : 2013-07-04
ISBN : 0199934959
Language : En, Es, Fr & De

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Book Description :

Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.

Neurobiology of Mental Disorders

Neurobiology of Mental Disorders Book
Author : Marcus Lira Brandão
Publisher : Nova Publishers
Release : 2006
ISBN : 9781594549144
Language : En, Es, Fr & De

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Book Description :

In writing this book, the authors have emphasised current perspectives on the neurobiology of mental disorders, not attempting to provide an exhaustive coverage of the field. Each chapter of the book represents a synthesis of the subject's state of the art. The first and third chapters were written by one of the Editors (FGG) and the sixth by the other (MLB). Each of the remaining chapters was extensively revised by one the authors. The book is a single-volume overview on the neurobiology of mental disorders, and was written for a broad audience. The authors aimed at the generally educated reader, who enjoys science and is interested in becoming acquainted with the remarkable new discoveries about how the nervous system executes mental functions. For this reason, they have provided, inside text boxes, background knowledge on the most relevant topics of each field. The authors hope that students from many areas will find here a clear and readable introduction to the present topic.

Viral Vector Approaches in Neurobiology and Brain Diseases

Viral Vector Approaches in Neurobiology and Brain Diseases Book
Author : Riccardo Brambilla
Publisher : Humana Press
Release : 2013-10-30
ISBN : 9781627036092
Language : En, Es, Fr & De

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Book Description :

Aiming toward improvement in the safety, efficiency, and specificity of viral vectors for neurobiological research and clinical applications, Viral Vector Approaches in Neurobiology and Brain Diseases covers key aspects related to the use of viral vectors in neuroscience, with a major emphasis on basic mechanisms of synaptic plasticity, learning, and memory, as well as molecular neuropharmacology and experimental animal models of brain disorders. The volume begins by delving into features of the viral vectors currently available in neuroscience and their production methods, and it then continues onward to examples of successful applications of viral vector technology to psychiatric and memory research, current applications of viral vector technology in the context of neurological disorders, as well as various cutting-edge applications of viral vector technology to neuroscience, including optogenetics. Written for the Neuromethods series, the chapters of this book contain the kind of detailed description and implementation advice that promotes successful, repeatable results. Practical and up to date, Viral Vector Approaches in Neurobiology and Brain Diseases will be useful not only to neurobiologists wishing to routinely use viral vectors in the laboratory but also to experienced scientists needing detailed new protocols for a variety of experimental applications.

Neurobiology of Psychiatric Disorders

Neurobiology of Psychiatric Disorders Book
Author : Thomas E. Schlaepfer,Charles B. Nemeroff
Publisher : Elsevier
Release : 2012
ISBN : 0444520023
Language : En, Es, Fr & De

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Book Description :

This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Charney Nestler s Neurobiology of Mental Illness

Charney   Nestler s Neurobiology of Mental Illness Book
Author : Dennis S. Charney,Pamela B. Sklar
Publisher : Oxford University Press
Release : 2018-01-12
ISBN : 019068142X
Language : En, Es, Fr & De

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Book Description :

Preceded by Neurobiology of mental illness / edited by Dennis S. Charney ... [et al.]. 4th ed. 2013.

Computational Models of Brain and Behavior

Computational Models of Brain and Behavior Book
Author : Ahmed A. Moustafa
Publisher : John Wiley & Sons
Release : 2017-11-13
ISBN : 1119159067
Language : En, Es, Fr & De

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Book Description :

A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.

Brain Disorders in Critical Illness

Brain Disorders in Critical Illness Book
Author : Robert D. Stevens,Tarek Sharshar,E. Wesley Ely
Publisher : Cambridge University Press
Release : 2013-09-19
ISBN : 1107029198
Language : En, Es, Fr & De

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Book Description :

Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This concise clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.

CRISP Thesaurus

CRISP Thesaurus Book
Author : Anonim
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download CRISP Thesaurus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neuroscience

Neuroscience Book
Author : Alan Longstaff
Publisher : Garland Science
Release : 2005
ISBN : 9780415351881
Language : En, Es, Fr & De

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Book Description :

This new edition will be an even more tightly constructed overview of the subject that the first edition that will enable easy access to core information making it an ideal resource for learning and studying before exams. New topics include emotion, language, schizophrenia and depression.

Neurobiology of PTSD

Neurobiology of PTSD Book
Author : Israel Liberzon,Kerry Ressler
Publisher : Oxford University Press
Release : 2016-08-08
ISBN : 0190215429
Language : En, Es, Fr & De

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Book Description :

Neurobiology of PTSD outlines the basic neural mechanisms that mediate complex responses and adaptations to psychological trauma, describing how these biological processes are impaired in individuals with posttraumatic stress disorder (PTSD). Throughout three comprehensive sections, expert authors present detailed analysis of the neural circuitry of emotion, biological findings in post-traumatic stress disorder, and neuroscience informed treatment and prevention. This book is a foundational resource for psychiatrists, neuroscientists, psychologists, and allied health professionals.

Brain Norepinephrine

Brain Norepinephrine Book
Author : Gregory A. Ordway,Michael A. Schwartz,Alan Frazer
Publisher : Cambridge University Press
Release : 2007-02-15
ISBN : 1139461702
Language : En, Es, Fr & De

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Book Description :

This book was first published in 2007. Norepinephrine is a chemical neurotransmitter. Drugs that directly manipulate central nervous system (CNS) norepinephrine are being developed targeting noradrenergic neurons to deliver therapeutic effects. Noradrenergic drugs have been proven effective for depression and ADHD, and new disease indications are being identified. A team of experts provides the reader with a thorough understanding of the anatomy, physiology, molecular biology, pharmacology and therapeutics of norepinephrine in the brain, including an extensive review of the role of norepinephrine in brain diseases. The book is divided into four sections: the basic biology of norepinephrine; the role that norepinephrine plays in behavior; evidence of norepinephrine's role in CNS diseases, and the pharmacology and therapeutics of noradrenergic drugs in the treatment of psychiatric and neurological disorders.

Neurobiology of Disease

Neurobiology of Disease Book
Author : Anonim
Publisher : Elsevier
Release : 2011-09-06
ISBN : 9780080466385
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Disease is aimed at any basic scientist or clinician scientist teaching a course or conducting research on the basic science underlying the major neurological diseases. It provides an excellent overview of cutting-edge research on the fundamental disorders of the nervous system, including physiological and molecular aspects of dysfunction. The major categories of neurological disease are covered, and the chapters provide specific information about particular diseases exemplifying each of these categories. Sufficient clinical information is included to put into perspective the basic mechanisms discussed. The book assembles a world-class team of section editors and chapters written by acknowledged experts in their respective fields. Provides cutting edge information about fundamental mechanisms underlying neurological diseases Amply supplied with tables, illustrations and references Includes supporting clinical information putting the mechanisms of disease into perspective

Imaging of the Human Brain in Health and Disease

Imaging of the Human Brain in Health and Disease Book
Author : Philip Seeman,Bertha Madras
Publisher : Elsevier
Release : 2013-11-15
ISBN : 012418684X
Language : En, Es, Fr & De

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Book Description :

Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. A focused introduction to imaging healthy and diseased brains Focuses on the primary neurotransmitter release Includes sigma, acetylcholine, opioid, and dopamine receptors Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

Biomaterials for Brain Therapy and Repair

Biomaterials for Brain Therapy and Repair Book
Author : Sara Pedron,Brendan A.C. Harley
Publisher : Frontiers Media SA
Release : 2019-02-06
ISBN : 2889457478
Language : En, Es, Fr & De

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Book Description :

Prevalence of brain related diseases is expected to increase significantly in the next decades. Therefore, there is a vital need to develop effective, personalized models of human brain that can provide information about brain development, and the unique neurobiology of brain disorders. The use of biomaterials can play a strategic role for the future understanding and treatment of complex CNS diseases. Three-dimensional brain cultures have shown promise in disease modelling, cell transplantation and modulation of tissue repair.

Neurological Disorders of Children

Neurological Disorders of Children Book
Author : Anonim
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Neurological Disorders of Children book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

MR Spectroscopy of Pediatric Brain Disorders

MR Spectroscopy of Pediatric Brain Disorders Book
Author : Stefan Blüml,Ashok Panigrahy
Publisher : Springer Science & Business Media
Release : 2012-12-02
ISBN : 1441958649
Language : En, Es, Fr & De

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Book Description :

Magnetic resonance spectroscopy (MRS) is a modality available on most clinical MR scanners and readily integrated with standard MR imaging (MRI). For the brain in particular, MRS has been a powerful research tool providing additional clinically relevant information for several disease families such as brain tumors, metabolic disorders, and systemic diseases. The most widely-available MRS method, proton (1H; hydrogen) spectroscopy, is FDA approved for general use in the US and can be ordered by clinicians for patient studies if indicated. There are several books available that describe applications of MRS in adults. However, to the best of our knowledge there is currently no book available that focuses exclusively on applications in pediatrics. MR spectroscopy in the pediatric population is different from adults for two main reasons. Particularly in the newborn phase the brain undergoes biochemical maturation with dramatic changes of the "normal" biochemical fingerprint. Secondly, brain diseases in the pediatric population are different from adult disorders. For example, brain tumors, which are mostly gliomas in the adults, often originate from different cell types and are also more diverse even within the same type and grade of tumor. This diversity of diseases and its implications for MR spectroscopy has not been addressed sufficiently in the literature, we believe. The target audience for "MR Spectroscopy of Pediatric Brain Disorders" are thus both clinicians and researchers involved with pediatric brain disorders. This includes radiologists, neurologists, neurooncologists, neurosurgeons, and more broadly the neuroscience and neurobiology community. This book will provide the necessary background information to understand the basics of MR spectroscopy. This will be followed by a detailed discussion of the normal biochemical maturation which will highlight the metabolic differences between the pediatric and adult brain. Thereafter, in SECTION I individual chapters will address various pediatric brain disease families. Of particular importance for pediatrics are case studies. For that reason, SECTION II will contain a large number of case studies. This will be particularly important for clinicians who may want to see examples of MRS for various conditions. A standardized format will be used for case reports that allow the reader to quickly understand the history of each case presented and the significance of the findings. The case reports will also include information from other imaging modalities to point out any added value of MRS in addition to conventional studies and clinical information. This section is necessary because the format of providing more complete information about individual patients is not practical for the chapters in SECTION I.

Neurological Disorders in Famous Artists

Neurological Disorders in Famous Artists   Book
Author : J. Bogousslavsky,L. Tatu
Publisher : Karger Medical and Scientific Publishers
Release : 2018-10-18
ISBN : 3318063940
Language : En, Es, Fr & De

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Book Description :

In this fourth volume of the popular series 'Neurological Disorders in Famous Artists' we once again delve into the minds of writers, painters, and poets in order to gain better insight on how neurological and psychiatric diseases can influence creativity. The issue of schizophrenia, the interaction between psychological instability and drug abuse, and the intricate association between organic wounds and shell-shock disorders are illustrated with the examples of Franz Kafka, Raymond Roussel, and Louis-Ferdinand Céline and their writings. Dementia has been specifically studied before, including in the previous volumes of Neurological Disorders in Famous Artists. It is revisited here in order to present the striking and well-documented case of Willem de Kooning, which inspired a new approach. Apart from issues that sometimes border on neuropsychiatry, purer neurological cases such as post-amputation limb pain (Arthur Rimbaud) or tabetic ataxia (Edouard Manet) are presented as well. Other fascinating life trajectories associated with cerebral or psychological changes include those of the writers Bjornsen, Tolstoi, Turgeniev, Mann, Ibsen, and Pavese.

The Wiley Blackwell Handbook of Forensic Neuroscience

The Wiley Blackwell Handbook of Forensic Neuroscience Book
Author : Anthony R. Beech,Adam J. Carter,Ruth E. Mann,Pia Rotshtein
Publisher : John Wiley & Sons
Release : 2018-03-26
ISBN : 1118650921
Language : En, Es, Fr & De

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Book Description :

Explores how the explosion of neuroscience-based evidence in recent years has led to a fundamental change in how forensic psychology can inform working with criminal populations. This book communicates knowledge and research findings in the neurobiological field to those who work with offenders and those who design policy for offender rehabilitation and criminal justice systems, so that practice and policy can be neurobiologically informed, and research can be enhanced. Starting with an introduction to the subject of neuroscience and forensic settings, The Wiley Blackwell Handbook of Forensic Neuroscience then offers in-depth and enlightening coverage of the neurobiology of sex and sexual attraction, aggressive behavior, and emotion regulation; the neurobiological bases to risk factors for offending such as genetics, developmental, alcohol and drugs, and mental disorders; and the neurobiology of offending, including psychopathy, antisocial personality disorders, and violent and sexual offending. The book also covers rehabilitation techniques such as brain scanning, brain-based therapy for adolescents, and compassion-focused therapy. The book itself: Covers a wide array of neuroscience research Chapters by renowned neuroscientists and criminal justice experts Topics covered include the neurobiology of aggressive behavior, the neuroscience of deception, genetic contributions to psychopathy, and neuroimaging-guided treatment Offers conclusions for practitioners and future directions for the field. The Wiley Blackwell Handbook of Forensic Neuroscience is a welcome book for all researchers, practitioners, and postgraduate students involved with forensic psychology, neuroscience, law, and criminology.

Clinical Neuroscience E Book

Clinical Neuroscience E Book Book
Author : Paul Johns
Publisher : Elsevier Health Sciences
Release : 2014-04-17
ISBN : 1455742120
Language : En, Es, Fr & De

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Book Description :

This book provides a clear and readable introduction to the central concepts of clinical neuroscience. The first part of the book deals with fundamental areas of neuroscience required for a sound understanding of brain disease. This is followed by an account of the neurobiology of the most common and important brain diseases of the western world (stroke, epilepsy, Alzheimer's disease, Parkinson's disease and multiple sclerosis). The book is in the same general style as the successful Crossman: Neuronatomy with extensive colour illustrations. Short, affordable and readable introductory level text in the smae style as Crossman: Neuroanatomy. Assumes little previous neuroscience knowledge. Explains fundamental concepts without overwhelming detail Focuses on clinically relevant material. Includes the most common and important neurological disorders.