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Neurobiology Of Alcohol Dependence

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Neurobiology of Alcohol Dependence

Neurobiology of Alcohol Dependence Book
Author : Antonio Noronha,Changhai Cui,R. Adron Harris,John C. Crabbe
Publisher : Academic Press
Release : 2014
ISBN : 9780124059412
Language : En, Es, Fr & De

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Book Description :

Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependence Chapters authored by leaders in the field around the globe - the broadest, most expert coverage available

Behavioral Neurobiology of Alcohol Addiction

Behavioral Neurobiology of Alcohol Addiction Book
Author : Wolfgang Sommer,Rainer Spanagel
Publisher : Springer Science & Business Media
Release : 2012-07-28
ISBN : 3642287204
Language : En, Es, Fr & De

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Book Description :

The question how alcohol alters mood states and why this may end up becoming an addiction is puzzling alcohol researchers since decades. In this volume, an assembly of highly distinguished experts and leaders in alcohol addiction research provides lucid presentations of the current knowledge and research challenges as well as interesting viewpoints on future research directions aimed to stimulate communication and convergence between clinical and preclinical researchers, and to renew interest in the vibrant field of alcohol addiction research among a wide scientifically minded audience. Five Current Topics are discussed in this volume: Neurobiological mechanisms of alcoholism, Genetics, Clinical phenotypes and their preclinical models, Brain imaging, and Translational approaches for treatment development, both pharmacological and non-pharmacological. These areas have in our opinion brought alcohol research substantially forward and influenced our thinking about how to reach our common paramount goal, namely to offer effective treatment solutions for an extensive group of patients with largely unmet medical needs.

Neurobiology of Alcohol and the Brain

Neurobiology of Alcohol and the Brain Book
Author : Ashok K. Singh
Publisher : Academic Press
Release : 2020-10-01
ISBN : 0128198915
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Alcohol and the Brain addresses addiction related problems, reviewing both mechanisms and withdrawal systems surrounding alcohol addiction. Chapters discuss mechanisms of rewarding, aversive effects, alcohol’s interaction with other drugs (and ensuing adverse consequences), and current and novel treatments. Lastly, the reader is provided with examples of an experimental study that describes the possible protective effects of gold nanoparticles against alcohol addiction in rats subjected to alcohol self-administration. Provides an exhaustive overview of neurobiology of alcohol addiction, including significant recent advances Discusses the mechanisms underlying the adverse effects of alcohol-drug mixtures Includes recent experimental studies on gold nanoparticles

Neuroscience Pathways to Alcohol Dependence Part I Overview of the Neurobiology of Dependence

Neuroscience  Pathways to Alcohol Dependence  Part I    Overview of the Neurobiology of Dependence Book
Author : Edith V. Sullivan
Publisher : Unknown
Release : 2009-05
ISBN : 9781437913620
Language : En, Es, Fr & De

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Book Description :

Contents: Neurobiology of Alcohol Dependence: Focus on Motivational Mechanisms; Communication Networks in the Brain: Neurons, Receptors, Neurotransmitters, and Alcohol; Translational Studies of Alcoholism: Bridging the Gap; Strategies to Study the Neuroscience of Alcoholism; Positron Emission Tomography as a Tool for Studying Alcohol Abuse; From Event-Related Potential to Oscillations: Genetic Diathesis in Brain (Dys)Function and Alcohol Dependence; The Use of Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging in Alcohol Research; Magnetic Resonance Imaging Approaches for Studying Alcoholism Using Mouse Models; Laser-Assisted Microdissection; Proteomic Solutions for Analytical Challenges Associated with Alcohol Research; On the Use of Short-Interfering RNA to Study Alcohol-Related Genes; Viral Delivery of Small-Hairpin RNAs for Reducing Gene Expression in the Rodent Brain; Quantitative Trait Locus Analysis: Multiple Cross and Heterogeneous Stock Mapping; Interval-Specific Congenic Animals for High-Resolution Quantitative Trait Loci Mapping; Single-Nucleotide Polymorphism Masking; Expression Quantitative Trait Loci and the PhenoGen Database; Integrative Genetic Analysis of Alcohol Dependence; Using the GeneNetwork Web Resources; Conclusions; Glossary. Illus.

Neuroscience of Alcohol

Neuroscience of Alcohol Book
Author : Victor R. Preedy
Publisher : Academic Press
Release : 2019-03-15
ISBN : 9780128131251
Language : En, Es, Fr & De

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Book Description :

Alcohol is one of the world's most common addictive substances, with about 2 billion individuals worldwide consuming it in one form or another and 3 million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. Effective treatments are contingent on a thorough understanding of the neuroscience of ethyl alcohol and the mechanisms of addiction to the substance in the brain. Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain in a single source. Offering thorough coverage of all aspects of alcohol research, treatment, and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Integrates cutting-edge research on the pharmacological, cellular, and molecular aspects of alcohol use along with its effects on neurobiological function Discusses alcohol use as a component of dual-use and poly addictions, and outlines numerous screening and treatment strategies for alcohol misuse Covers both physical and psychological effects of alcohol use and withdrawal to provide fully formed view of alcohol dependency and its effects

Alcohol

Alcohol Book
Author : George F. Koob,Michael A. Arends,Mandy McCracken,Michel Le Moal
Publisher : Academic Press
Release : 2021-07-07
ISBN : 0128167947
Language : En, Es, Fr & De

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Book Description :

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. ALCOHOL, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Outlines the history and behavioral mechanism of action of alcohol relevant to the neurobiology of alcohol addiction Includes neurocircuitry, cellular, and molecular neurobiological mechanisms of alcohol addiction in each stage of the addiction cycle Explores evolving areas of research associated with all three stages of the alcohol addiction cycle, including neurobiological studies of neurodevelopmental effects of early exposure to alcohol, sleep disturbances caused by alcohol, pain interactions with alcohol, sex differences in the response to alcohol, and epigenetic/genetic interactions with alcohol.

Alcohol

Alcohol Book
Author : George F. Koob,Michael A. Arends, BS,Mandy McCracken,Michel Le Moal
Publisher : Elsevier
Release : 2021-07-23
ISBN : 0128167939
Language : En, Es, Fr & De

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Book Description :

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. ALCOHOL, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Outlines the history and behavioral mechanism of action of alcohol relevant to the neurobiology of alcohol addiction? Includes neurocircuitry, cellular, and molecular neurobiological mechanisms of alcohol addiction in each stage of the addiction cycle Explores evolving areas of research associated with all three stages of the alcohol addiction cycle, including neurobiological studies of neurodevelopmental effects of early exposure to alcohol, sleep disturbances caused by alcohol, pain interactions with alcohol, sex differences in the response to alcohol, and epigenetic/genetic interactions with alcohol.

Neurobiology of Alcohol Abuse

Neurobiology of Alcohol Abuse Book
Author : William J. Haugen Light
Publisher : Charles C Thomas Pub Limited
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Neurobiology of Alcohol Abuse book written by William J. Haugen Light, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Alcohol and the Nervous System

Alcohol and the Nervous System Book
Author : Edith V. Sullivan,Adolf Pfefferbaum
Publisher : Elsevier
Release : 2014-10-08
ISBN : 0444626220
Language : En, Es, Fr & De

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Book Description :

Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function

Research on the Neurobiology of Alcohol Use Disorders

Research on the Neurobiology of Alcohol Use Disorders Book
Author : Leo Sher
Publisher : Nova Publishers
Release : 2008
ISBN : 9781604561975
Language : En, Es, Fr & De

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Book Description :

This book describes the neurobiological mechanisms of alcohol abuse and dependence including the role of serotonergeic, dopaminergic, noradrenergic, and hypothalamic-piturary adrenal systems in alcohol use disorders and the results of neuroimaging studies are presented. The neurobiology of comorbidity of alcohol use disorders with other psychiatric disorders are also discussed. Research on the neurobiology of alcohol abuse and dependence is very important. Therefore, this book will be of interest to biomedical researchers, physicians, and other clinicians, students, and anyone who is interested in the mechanisms of addictive disorders.

Neurobiology of Addiction

Neurobiology of Addiction Book
Author : George F. Koob,Michel Le Moal
Publisher : Elsevier
Release : 2005-11-11
ISBN : 0080497373
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. · Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

Alcohol Problems in Adolescents and Young Adults

Alcohol Problems in Adolescents and Young Adults Book
Author : Marc Galanter
Publisher : Springer Science & Business Media
Release : 2006-03-30
ISBN : 0306486261
Language : En, Es, Fr & De

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Book Description :

Alcohol continues to be the substance of choice for today’s youth, leading to serious physical, psychological, and social consequences. Alcohol Problems in Adolescents and Young Adults ably addresses this growing trend. The latest entry in the Recent Developments in Alcoholism series, it comprehensively presents a wide-ranging clinical picture of teen drinking - epidemiology, neurobiology, behavioral phenomena, diagnostic and assessment issues, prevention and treatment data - in a developmental context. Fifty expert contributors display the scientific rigor, practical wisdom, and nuanced analysis that readers have come to expect from previous volumes. Among the subjects studied in depth: - Initiation of alcohol use/abuse - Risk and protective factors for alcohol dependence - High-risk adolescent populations - Drinking habits of college students - Long-range consequences of teenage drinking - Family-, school-, and community-based prevention programs - Treatment of comorbid substance and psychiatric disorders Clinicians, researchers, and policy makers will find this a bedrock source of evidence-based knowledge, whether one’s goal is choosing an age-appropriate assessment tool for eighth graders, preventing drinking among high school students, or understanding the alcohol-friendliness of campus culture. Here is a critical resource for all professionals dedicated to helping youngsters grow up sober.

Neurobiology of Addiction and Co Morbid Disorders

Neurobiology of Addiction and Co Morbid Disorders Book
Author : Anonim
Publisher : Academic Press
Release : 2021-03-01
ISBN : 0128203560
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Addiction and Comorbid Disorders, Volume 156, in the International Review of Neurobiology series, highlights new advances in the field of neurobiology, with this new volume presenting interesting chapters on topics such as Pain + Alcohol, Pain + Opioids, Traumatic Stress + Alcohol, Traumatic Stress + Cannabinoids, Traumatic Brain Injury and the Misuse of Alcohol, Opioids, and Cannabis, Depression + Addiction, Microbiome/cytokines + Addiction, Cognitive disorders + Alcohol, Neural stem cells, Neurogenesis and Addiction, Food Addiction, and Poly-drug Addiction. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the International Review of Neurobiology series Updated release includes the latest information on the Neurobiology of Addiction and Co-Morbid Disorders

Introduction to Addiction

Introduction to Addiction Book
Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
Publisher : Academic Press
Release : 2019-06-11
ISBN : 0128167955
Language : En, Es, Fr & De

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Book Description :

Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse. Provides neurobiological theories on how addiction works Explains addiction cycle stages of binge, withdrawal and anticipation Reviews the role of dopamine and the frontal cortex in addiction Discusses the neurocircuitry of reward and stress Includes animal models and neuroadaptational views on addiction

Compulsive Eating Behavior and Food Addiction

Compulsive Eating Behavior and Food Addiction Book
Author : Pietro Cottone,Catherine F Moore,Valentina Sabino,George F. Koob
Publisher : Academic Press
Release : 2019-07-24
ISBN : 0128163836
Language : En, Es, Fr & De

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Book Description :

Compulsive Eating Behavior and Food Addiction: Emerging Pathological Constructs is the first book of its kind to emphasize food addiction as an addictive disorder. This book focuses on the preclinical aspects of food addiction research, shifting the focus towards a more complex behavioral expression of pathological feeding and combining it with current research on neurobiological substrates. This book will become an invaluable reference for researchers in food addiction and compulsive eating constructs. Compulsive eating behavior is a pathological form of feeding that phenotypically and neurobiologically resembles the compulsive-like behaviors associated with both drug abuse and behavioral addictions. Compulsive eating behavior, including Binge Eating Disorder (BED), certain forms of obesity, and ‘food addiction’ affect an estimated 70 million individuals worldwide. Synthesizes clinical and preclinical perspectives on addictive eating behavior Identifies how food addiction is similar and/or different from other addictions Focuses on the underlying neurobiological mechanisms Provides information on therapeutic interventions for patients with food addiction

The Neurobiology of Addiction

The Neurobiology of Addiction Book
Author : Trevor W. Robbins,Barry J. Everitt,David J. Nutt
Publisher : Oxford University Press, USA
Release : 2010
ISBN : 0199562156
Language : En, Es, Fr & De

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Book Description :

In the past two decades, there have been astonishing advances in our understanding of the neurobiological basis and nature of drug addiction. We now know the initial molecular sites of action, at identified receptors, of virtually all of the major drugs of abuse including cocaine, heroin, and amphetamine, as well as legal drugs such as nicotine and alcohol. We also understand the main components of a 'reward system' and its connections to major brain regions involved in motivation and emotion, such as the amygdala, hippocampus, and prefrontal cortex. The Neurobiology of Addiction describes the latest advances in our understanding of addiction. It brings together world class researchers to debate the nature and extent of addiction, as well as its causes, consequences, and treatment. The focus of the book is on the brain processes underlying addiction, in terms of neural systems, neurochemical basis, and molecular changes. Several types of addiction are discussed ranging from illicit drugs - cocaine, amphetamine, and heroin to legal drugs - alcohol and nicotine. In addition, it explores increasingly common behavioural addictions such as gambling and obesity. Included are chapters on vulnerability to addiction, genetic factors, opponent motivational processes, animal models, relapse, cognitive deficits associated with drug abuse, new pharmacological treatments, and current controversies concerning different neuropsychological theories of addiction. Throughout, it reports on cutting edge research using brain imaging, and state of the art molecular methodology. The book will make fascinating reading for students and teachers in the field of neuroscience, pharmacology and psychology, as well as experts in the field.

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption Book
Author : Anonim
Publisher : Academic Press
Release : 2017-10-31
ISBN : 0128124741
Language : En, Es, Fr & De

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Book Description :

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption, Volume 136 in the International Review of Neurobiology series, provides an overview of the top candidate neuropeptides in the modulation of alcohol and drug abuse, also covering eating disorders and obesity. Topics covered in this latest release include Corticotropin Releasing Factor (CRF) and Addictive Behaviors, Dynorphin/Kappa Opioid Receptor Signaling in Pre-clinical Models of Alcohol, Drug, and Food Addiction, The Role of Ghrelin Signaling in Additive Behaviors, The Role of the Melanocortin System in Drug and Eating Disorders, Substance P and the Neurokinin-1 Receptor: The New CRH, and the Role of Neuropeptide Y (NPY) in Drug and Eating Disorders. The book uniquely highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders. Presents a recent overview of some of the top candidate neuropeptides in the modulation of alcohol and drug abuse, and in eating disorders and obesity Highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders Contains chapters that focus on a specific neuropeptide

Functional Plasticity and Genetic Variation

Functional Plasticity and Genetic Variation Book
Author : Anonim
Publisher : Academic Press
Release : 2010-10-28
ISBN : 9780123812773
Language : En, Es, Fr & De

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Book Description :

With recent advances of modern medicine more people reach the 'elderly age' around the globe and the number of dementia cases are ever increasing. This book is about various aspects of dementia and provides its readers with a wide range of thought-provoking sub-topics in the field of dementia. The ultimate goal of this monograph is to stimulate other physicians' and neuroscientists' interest to carry out more research projects into pathogenesis of this devastating group of diseases.

Psychostimulants

Psychostimulants Book
Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
Publisher : Academic Press
Release : 2020-05-05
ISBN : 0128169915
Language : En, Es, Fr & De

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Book Description :

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction are detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Psychostimulants, Volume 2 in the series, explores the molecular and cellular systems in the brain responsible for psychostimulant addiction, including both direct/indirect sympathomimetics and nonsympathomimetics. This volume introduces the readers to the history of psychostimulant use. The authors clearly differentiate the neurobiological effects into three distinct stages of the addiction cycle: binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Highlights recent advances in psychostimulant addiction Includes neurocircuitry, cellular and molecular neurobiological mechanisms of psychostimulant addiction Defines the abuse and addiction potentials of both direct and indirect sympathomimetics and nonsympathomimetics

Neurobiology of Alcohol Dependence

Neurobiology of Alcohol Dependence Book
Author : Antonio Noronha,Changhai Cui,Robert Adron Harris,John C. Crabbe
Publisher : Elsevier
Release : 2014-05-02
ISBN : 0124071554
Language : En, Es, Fr & De

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Book Description :

Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependence Chapters authored by leaders in the field around the globe — the broadest, most expert coverage available