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Neurobiology Of Alcohol Dependence

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Neurobiology of Alcohol and the Brain

Neurobiology of Alcohol and the Brain Book
Author : Ashok K. Singh
Publisher : Academic Press
Release : 2020-10-01
ISBN : 0128198915
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Alcohol and the Brain addresses addiction related problems, reviewing both mechanisms and withdrawal systems surrounding alcohol addiction. Chapters discuss mechanisms of rewarding, aversive effects, alcohol’s interaction with other drugs (and ensuing adverse consequences), and current and novel treatments. Lastly, the reader is provided with examples of an experimental study that describes the possible protective effects of gold nanoparticles against alcohol addiction in rats subjected to alcohol self-administration. Provides an exhaustive overview of neurobiology of alcohol addiction, including significant recent advances Discusses the mechanisms underlying the adverse effects of alcohol-drug mixtures Includes recent experimental studies on gold nanoparticles

Neurobiology of Alcohol Dependence

Neurobiology of Alcohol Dependence Book
Author : Antonio Noronha,Changhai Cui,Robert Adron Harris,John C. Crabbe
Publisher : Elsevier
Release : 2014-05-02
ISBN : 0124071554
Language : En, Es, Fr & De

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Book Description :

Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependence Chapters authored by leaders in the field around the globe — the broadest, most expert coverage available

Behavioral Neurobiology of Alcohol Addiction

Behavioral Neurobiology of Alcohol Addiction Book
Author : Wolfgang Sommer,Rainer Spanagel
Publisher : Springer Science & Business Media
Release : 2012-07-28
ISBN : 3642287204
Language : En, Es, Fr & De

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Book Description :

The question how alcohol alters mood states and why this may end up becoming an addiction is puzzling alcohol researchers since decades. In this volume, an assembly of highly distinguished experts and leaders in alcohol addiction research provides lucid presentations of the current knowledge and research challenges as well as interesting viewpoints on future research directions aimed to stimulate communication and convergence between clinical and preclinical researchers, and to renew interest in the vibrant field of alcohol addiction research among a wide scientifically minded audience. Five Current Topics are discussed in this volume: Neurobiological mechanisms of alcoholism, Genetics, Clinical phenotypes and their preclinical models, Brain imaging, and Translational approaches for treatment development, both pharmacological and non-pharmacological. These areas have in our opinion brought alcohol research substantially forward and influenced our thinking about how to reach our common paramount goal, namely to offer effective treatment solutions for an extensive group of patients with largely unmet medical needs.

Alcohol

Alcohol Book
Author : George F. Koob,Michael A. Arends,Mandy McCracken,Michel Le Moal
Publisher : Academic Press
Release : 2021-07-07
ISBN : 0128167947
Language : En, Es, Fr & De

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Book Description :

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. ALCOHOL, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Outlines the history and behavioral mechanism of action of alcohol relevant to the neurobiology of alcohol addiction Includes neurocircuitry, cellular, and molecular neurobiological mechanisms of alcohol addiction in each stage of the addiction cycle Explores evolving areas of research associated with all three stages of the alcohol addiction cycle, including neurobiological studies of neurodevelopmental effects of early exposure to alcohol, sleep disturbances caused by alcohol, pain interactions with alcohol, sex differences in the response to alcohol, and epigenetic/genetic interactions with alcohol.

Neuroscience Pathways to Alcohol Dependence Part I Overview of the Neurobiology of Dependence

Neuroscience  Pathways to Alcohol Dependence  Part I    Overview of the Neurobiology of Dependence Book
Author : Edith V. Sullivan
Publisher : Unknown
Release : 2009-05
ISBN : 9781437913620
Language : En, Es, Fr & De

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Book Description :

Contents: Neurobiology of Alcohol Dependence: Focus on Motivational Mechanisms; Communication Networks in the Brain: Neurons, Receptors, Neurotransmitters, and Alcohol; Translational Studies of Alcoholism: Bridging the Gap; Strategies to Study the Neuroscience of Alcoholism; Positron Emission Tomography as a Tool for Studying Alcohol Abuse; From Event-Related Potential to Oscillations: Genetic Diathesis in Brain (Dys)Function and Alcohol Dependence; The Use of Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging in Alcohol Research; Magnetic Resonance Imaging Approaches for Studying Alcoholism Using Mouse Models; Laser-Assisted Microdissection; Proteomic Solutions for Analytical Challenges Associated with Alcohol Research; On the Use of Short-Interfering RNA to Study Alcohol-Related Genes; Viral Delivery of Small-Hairpin RNAs for Reducing Gene Expression in the Rodent Brain; Quantitative Trait Locus Analysis: Multiple Cross and Heterogeneous Stock Mapping; Interval-Specific Congenic Animals for High-Resolution Quantitative Trait Loci Mapping; Single-Nucleotide Polymorphism Masking; Expression Quantitative Trait Loci and the PhenoGen Database; Integrative Genetic Analysis of Alcohol Dependence; Using the GeneNetwork Web Resources; Conclusions; Glossary. Illus.

Neurobiology of Addiction

Neurobiology of Addiction Book
Author : George F. Koob,Michel Le Moal
Publisher : Elsevier
Release : 2005-11-11
ISBN : 0080497373
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. · Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

The Neurobiology of Addiction

The Neurobiology of Addiction Book
Author : Trevor W. Robbins,Barry J. Everitt,David J. Nutt
Publisher : Oxford University Press, USA
Release : 2010
ISBN : 0199562156
Language : En, Es, Fr & De

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Book Description :

In the past two decades, there have been astonishing advances in our understanding of the neurobiological basis and nature of drug addiction. We now know the initial molecular sites of action, at identified receptors, of virtually all of the major drugs of abuse including cocaine, heroin, and amphetamine, as well as legal drugs such as nicotine and alcohol. We also understand the main components of a 'reward system' and its connections to major brain regions involved in motivation and emotion, such as the amygdala, hippocampus, and prefrontal cortex. The Neurobiology of Addiction describes the latest advances in our understanding of addiction. It brings together world class researchers to debate the nature and extent of addiction, as well as its causes, consequences, and treatment. The focus of the book is on the brain processes underlying addiction, in terms of neural systems, neurochemical basis, and molecular changes. Several types of addiction are discussed ranging from illicit drugs - cocaine, amphetamine, and heroin to legal drugs - alcohol and nicotine. In addition, it explores increasingly common behavioural addictions such as gambling and obesity. Included are chapters on vulnerability to addiction, genetic factors, opponent motivational processes, animal models, relapse, cognitive deficits associated with drug abuse, new pharmacological treatments, and current controversies concerning different neuropsychological theories of addiction. Throughout, it reports on cutting edge research using brain imaging, and state of the art molecular methodology. The book will make fascinating reading for students and teachers in the field of neuroscience, pharmacology and psychology, as well as experts in the field.

Research on the Neurobiology of Alcohol Use Disorders

Research on the Neurobiology of Alcohol Use Disorders Book
Author : Leo Sher
Publisher : Nova Publishers
Release : 2008
ISBN : 9781604561975
Language : En, Es, Fr & De

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Book Description :

This book describes the neurobiological mechanisms of alcohol abuse and dependence including the role of serotonergeic, dopaminergic, noradrenergic, and hypothalamic-piturary adrenal systems in alcohol use disorders and the results of neuroimaging studies are presented. The neurobiology of comorbidity of alcohol use disorders with other psychiatric disorders are also discussed. Research on the neurobiology of alcohol abuse and dependence is very important. Therefore, this book will be of interest to biomedical researchers, physicians, and other clinicians, students, and anyone who is interested in the mechanisms of addictive disorders.

Neurobiology of Addiction and Co Morbid Disorders

Neurobiology of Addiction and Co Morbid Disorders Book
Author : Anonim
Publisher : Academic Press
Release : 2021-03-01
ISBN : 0128203560
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Addiction and Comorbid Disorders, Volume 156, in the International Review of Neurobiology series, highlights new advances in the field of neurobiology, with this new volume presenting interesting chapters on topics such as Pain + Alcohol, Pain + Opioids, Traumatic Stress + Alcohol, Traumatic Stress + Cannabinoids, Traumatic Brain Injury and the Misuse of Alcohol, Opioids, and Cannabis, Depression + Addiction, Microbiome/cytokines + Addiction, Cognitive disorders + Alcohol, Neural stem cells, Neurogenesis and Addiction, Food Addiction, and Poly-drug Addiction. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the International Review of Neurobiology series Updated release includes the latest information on the Neurobiology of Addiction and Co-Morbid Disorders

Alcohol Problems in Adolescents and Young Adults

Alcohol Problems in Adolescents and Young Adults Book
Author : Marc Galanter
Publisher : Springer Science & Business Media
Release : 2006-03-30
ISBN : 0306486261
Language : En, Es, Fr & De

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Book Description :

Alcohol continues to be the substance of choice for today’s youth, leading to serious physical, psychological, and social consequences. Alcohol Problems in Adolescents and Young Adults ably addresses this growing trend. The latest entry in the Recent Developments in Alcoholism series, it comprehensively presents a wide-ranging clinical picture of teen drinking - epidemiology, neurobiology, behavioral phenomena, diagnostic and assessment issues, prevention and treatment data - in a developmental context. Fifty expert contributors display the scientific rigor, practical wisdom, and nuanced analysis that readers have come to expect from previous volumes. Among the subjects studied in depth: - Initiation of alcohol use/abuse - Risk and protective factors for alcohol dependence - High-risk adolescent populations - Drinking habits of college students - Long-range consequences of teenage drinking - Family-, school-, and community-based prevention programs - Treatment of comorbid substance and psychiatric disorders Clinicians, researchers, and policy makers will find this a bedrock source of evidence-based knowledge, whether one’s goal is choosing an age-appropriate assessment tool for eighth graders, preventing drinking among high school students, or understanding the alcohol-friendliness of campus culture. Here is a critical resource for all professionals dedicated to helping youngsters grow up sober.

Introduction to Addiction

Introduction to Addiction Book
Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
Publisher : Academic Press
Release : 2019-06-11
ISBN : 0128167955
Language : En, Es, Fr & De

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Book Description :

Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse. Provides neurobiological theories on how addiction works Explains addiction cycle stages of binge, withdrawal and anticipation Reviews the role of dopamine and the frontal cortex in addiction Discusses the neurocircuitry of reward and stress Includes animal models and neuroadaptational views on addiction

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption Book
Author : Anonim
Publisher : Academic Press
Release : 2017-10-31
ISBN : 0128124741
Language : En, Es, Fr & De

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Book Description :

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption, Volume 136 in the International Review of Neurobiology series, provides an overview of the top candidate neuropeptides in the modulation of alcohol and drug abuse, also covering eating disorders and obesity. Topics covered in this latest release include Corticotropin Releasing Factor (CRF) and Addictive Behaviors, Dynorphin/Kappa Opioid Receptor Signaling in Pre-clinical Models of Alcohol, Drug, and Food Addiction, The Role of Ghrelin Signaling in Additive Behaviors, The Role of the Melanocortin System in Drug and Eating Disorders, Substance P and the Neurokinin-1 Receptor: The New CRH, and the Role of Neuropeptide Y (NPY) in Drug and Eating Disorders. The book uniquely highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders. Presents a recent overview of some of the top candidate neuropeptides in the modulation of alcohol and drug abuse, and in eating disorders and obesity Highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders Contains chapters that focus on a specific neuropeptide

Alcohol Dependence Neurobiology Diagnosis and Treatment

Alcohol Dependence  Neurobiology Diagnosis and Treatment Book
Author : Anonim
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Alcohol Dependence Neurobiology Diagnosis and Treatment book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neurobiology of Alcohol Abuse

Neurobiology of Alcohol Abuse Book
Author : William J. Haugen Light
Publisher : Charles C Thomas Pub Limited
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Neurobiology of Alcohol Abuse book written by William J. Haugen Light, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neurobiology of Addictions

Neurobiology of Addictions Book
Author : Shulamith L A Straussner,Richard T. Spence,Diana M. Dinitto
Publisher : Routledge
Release : 2014-02-24
ISBN : 131782556X
Language : En, Es, Fr & De

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Book Description :

Bridge the gap between the physical foundations of substance abuse and the psychosocial approaches that can treat it! This groundbreaking book offers helping professionals a thorough introduction to the neurobiological aspects of substance abuse. It presents the basic information on the subject, including the various neurobiological theories of addiction, and places them in a psychosocial context. Its clear and straightforward style connects the theoretical information with practical applications. This is an essential resource for substance abuse counselors, researchers, therapists, and social workers. Neurobiology of Addictions offers sound, tested information on substance abuse issues, including: neurobiological theories of addiction integrating drug treatments and therapeutic interventions using neurobiology to discover substance abuse in clients of various ages perspectives from social work, pharmacology, biology, and neuroscience

Functional Plasticity and Genetic Variation

Functional Plasticity and Genetic Variation Book
Author : Anonim
Publisher : Academic Press
Release : 2010-10-28
ISBN : 9780123812773
Language : En, Es, Fr & De

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Book Description :

With recent advances of modern medicine more people reach the 'elderly age' around the globe and the number of dementia cases are ever increasing. This book is about various aspects of dementia and provides its readers with a wide range of thought-provoking sub-topics in the field of dementia. The ultimate goal of this monograph is to stimulate other physicians' and neuroscientists' interest to carry out more research projects into pathogenesis of this devastating group of diseases.

The Science of Addiction From Neurobiology to Treatment

The Science of Addiction  From Neurobiology to Treatment Book
Author : Carlton K. Erickson
Publisher : W. W. Norton & Company
Release : 2007-02-17
ISBN : 9780393076226
Language : En, Es, Fr & De

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Book Description :

Runner-up winner of the Hamilton Book Author Award, this book is a comprehensive overview of the neurobiology behind addictions. Neuroscience is clarifying the causes of compulsive alcohol and drug use––while also shedding light on what addiction is, what it is not, and how it can best be treated––in exciting and innovative ways. Current neurobiological research complements and enhances the approaches to addiction traditionally taken in social work and psychology. However, this important research is generally not presented in a forthright, jargon-free way that clearly illustrates its relevance to addiction professionals. The Science of Addiction presents a comprehensive overview of the roles that brain function and genetics play in addiction. It explains in an easy-to-understand way changes in the terminology and characterization of addiction that are emerging based upon new neurobiological research. The author goes on to describe the neuroanatomy and function of brain reward sites, and the genetics of alcohol and other drug dependence. Chapters on the basic pharmacology of stimulants and depressants, alcohol, and other drugs illustrate the specific and unique ways in which the brain and the central nervous system interact with, and are affected by, each of these substances Erickson discusses current and emerging treatments for chemical dependence, and how neuroscience helps us understand the way they work. The intent is to encourage an understanding of the body-mind connection. The busy clinical practitioner will find the chapter on how to read and interpret new research findings on the neurobiological basis of addiction useful and illuminating. This book will help the almost 21.6 million Americans, and millions more worldwide, who abuse or are dependent on drugs by teaching their caregivers (or them) about the latest addiction science research. It is also intended to help addiction professionals understand the foundations and applications of neuroscience, so that they will be able to better empathize with their patients and apply the science to principles of treatment.

Special Issue Neurobiology of Addiction

Special Issue  Neurobiology of Addiction Book
Author : Avram Goldstein,Eric J. Nestler
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Special Issue Neurobiology of Addiction book written by Avram Goldstein,Eric J. Nestler, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Neurobiology of Drug and Alcohol Addiction

The Neurobiology of Drug and Alcohol Addiction Book
Author : Peter W. Kalivas,Herman H. Samson
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Papers of a conference on [title] held by the New York Academy of Sciences, July 1991, in Spokane, Washington. No index. Annotation copyrighted by Book News, Inc., Portland, OR

Psychostimulants

Psychostimulants Book
Author : George F. Koob,Michael A. Arends,Many Mccracken,Michel Lemoal
Publisher : Academic Press
Release : 2020-05-05
ISBN : 0128169915
Language : En, Es, Fr & De

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Book Description :

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction are detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Psychostimulants, Volume 2 in the series, explores the molecular and cellular systems in the brain responsible for psychostimulant addiction, including both direct/indirect sympathomimetics and nonsympathomimetics. This volume introduces the readers to the history of psychostimulant use. The authors clearly differentiate the neurobiological effects into three distinct stages of the addiction cycle: binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Highlights recent advances in psychostimulant addiction Includes neurocircuitry, cellular and molecular neurobiological mechanisms of psychostimulant addiction Defines the abuse and addiction potentials of both direct and indirect sympathomimetics and nonsympathomimetics