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Neurobiology Of Alcohol And The Brain

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Neurobiology of Alcohol and the Brain

Neurobiology of Alcohol and the Brain Book
Author : Ashok K. Singh
Publisher : Academic Press
Release : 2020-10-01
ISBN : 0128198915
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Alcohol and the Brain addresses addiction related problems, reviewing both mechanisms and withdrawal systems surrounding alcohol addiction. Chapters discuss mechanisms of rewarding, aversive effects, alcohol’s interaction with other drugs (and ensuing adverse consequences), and current and novel treatments. Lastly, the reader is provided with examples of an experimental study that describes the possible protective effects of gold nanoparticles against alcohol addiction in rats subjected to alcohol self-administration. Provides an exhaustive overview of neurobiology of alcohol addiction, including significant recent advances Discusses the mechanisms underlying the adverse effects of alcohol-drug mixtures Includes recent experimental studies on gold nanoparticles

Behavioral Neurobiology of Alcohol Addiction

Behavioral Neurobiology of Alcohol Addiction Book
Author : Wolfgang Sommer,Rainer Spanagel
Publisher : Springer Science & Business Media
Release : 2012-07-28
ISBN : 3642287204
Language : En, Es, Fr & De

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Book Description :

The question how alcohol alters mood states and why this may end up becoming an addiction is puzzling alcohol researchers since decades. In this volume, an assembly of highly distinguished experts and leaders in alcohol addiction research provides lucid presentations of the current knowledge and research challenges as well as interesting viewpoints on future research directions aimed to stimulate communication and convergence between clinical and preclinical researchers, and to renew interest in the vibrant field of alcohol addiction research among a wide scientifically minded audience. Five Current Topics are discussed in this volume: Neurobiological mechanisms of alcoholism, Genetics, Clinical phenotypes and their preclinical models, Brain imaging, and Translational approaches for treatment development, both pharmacological and non-pharmacological. These areas have in our opinion brought alcohol research substantially forward and influenced our thinking about how to reach our common paramount goal, namely to offer effective treatment solutions for an extensive group of patients with largely unmet medical needs.

Neurobiology of Alcohol Dependence

Neurobiology of Alcohol Dependence Book
Author : Antonio Noronha,Changhai Cui,R. Adron Harris,John C. Crabbe
Publisher : Academic Press
Release : 2014
ISBN : 9780124059412
Language : En, Es, Fr & De

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Book Description :

Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependence Chapters authored by leaders in the field around the globe - the broadest, most expert coverage available

Alcohol and the Nervous System

Alcohol and the Nervous System Book
Author : Edith V. Sullivan,Adolf Pfefferbaum
Publisher : Elsevier
Release : 2014-10-08
ISBN : 0444626220
Language : En, Es, Fr & De

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Book Description :

Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function

Neuroscience Pathways to Alcohol Dependence Part I Overview of the Neurobiology of Dependence

Neuroscience  Pathways to Alcohol Dependence  Part I    Overview of the Neurobiology of Dependence Book
Author : Edith V. Sullivan
Publisher : Unknown
Release : 2009-05
ISBN : 9781437913620
Language : En, Es, Fr & De

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Book Description :

Contents: Neurobiology of Alcohol Dependence: Focus on Motivational Mechanisms; Communication Networks in the Brain: Neurons, Receptors, Neurotransmitters, and Alcohol; Translational Studies of Alcoholism: Bridging the Gap; Strategies to Study the Neuroscience of Alcoholism; Positron Emission Tomography as a Tool for Studying Alcohol Abuse; From Event-Related Potential to Oscillations: Genetic Diathesis in Brain (Dys)Function and Alcohol Dependence; The Use of Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging in Alcohol Research; Magnetic Resonance Imaging Approaches for Studying Alcoholism Using Mouse Models; Laser-Assisted Microdissection; Proteomic Solutions for Analytical Challenges Associated with Alcohol Research; On the Use of Short-Interfering RNA to Study Alcohol-Related Genes; Viral Delivery of Small-Hairpin RNAs for Reducing Gene Expression in the Rodent Brain; Quantitative Trait Locus Analysis: Multiple Cross and Heterogeneous Stock Mapping; Interval-Specific Congenic Animals for High-Resolution Quantitative Trait Loci Mapping; Single-Nucleotide Polymorphism Masking; Expression Quantitative Trait Loci and the PhenoGen Database; Integrative Genetic Analysis of Alcohol Dependence; Using the GeneNetwork Web Resources; Conclusions; Glossary. Illus.

Alcohol and Neurobiology

Alcohol and Neurobiology Book
Author : Ronald R. Watson
Publisher : CRC Press
Release : 1992-06-24
ISBN : 9780849379352
Language : En, Es, Fr & De

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Book Description :

The neurological consequences of alcohol abuse need additional research concentrating on prevention and treatment. Public attention and research efforts are being driven by an ever- increasing understanding of the problems and magnitude of alcohol on neurological development. The 10 million alcohol-abusing adults, along with unborn children exposed to alcohol in utero, cost the people of the U.S. more than $100 billion in lost wages, health care, theft, damaged mental functions, and shortened life span. An intimate, detailed knowledge of the effects of alcohol on the biochemical reactions and neurological changes is critical in preventing or treating abuse. We must study the mechanisms of ethanol's effects on the neurological system at a cellular and systematic level to understand its action. These include modifications of hormonal regulation and production with its major functional consequences. Brain development including its cells are a major focus and emphasis of this volume. The progress of research over the past decade is encouraging as we begin to summarize and evaluate in detail advances in understanding changes in the brain's biochemistry and physiology caused by ethanol. This information will assist the researcher, clinician, and student in comprehending the complex changes caused by direct and indirect effects of single drugs at the cellular level.

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption Book
Author : Anonim
Publisher : Academic Press
Release : 2017-10-31
ISBN : 0128124741
Language : En, Es, Fr & De

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Book Description :

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption, Volume 136 in the International Review of Neurobiology series, provides an overview of the top candidate neuropeptides in the modulation of alcohol and drug abuse, also covering eating disorders and obesity. Topics covered in this latest release include Corticotropin Releasing Factor (CRF) and Addictive Behaviors, Dynorphin/Kappa Opioid Receptor Signaling in Pre-clinical Models of Alcohol, Drug, and Food Addiction, The Role of Ghrelin Signaling in Additive Behaviors, The Role of the Melanocortin System in Drug and Eating Disorders, Substance P and the Neurokinin-1 Receptor: The New CRH, and the Role of Neuropeptide Y (NPY) in Drug and Eating Disorders. The book uniquely highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders. Presents a recent overview of some of the top candidate neuropeptides in the modulation of alcohol and drug abuse, and in eating disorders and obesity Highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders Contains chapters that focus on a specific neuropeptide

Neurobiology of Addiction

Neurobiology of Addiction Book
Author : George F. Koob,Michel Le Moal
Publisher : Elsevier
Release : 2005-11-11
ISBN : 0080497373
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. · Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

Drugs Addiction and the Brain

Drugs  Addiction  and the Brain Book
Author : George F. Koob,Michael A. Arends,Michel Le Moal
Publisher : Academic Press
Release : 2014-07-12
ISBN : 0123869595
Language : En, Es, Fr & De

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Book Description :

Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction

Neurobiology of Alcohol Abuse

Neurobiology of Alcohol Abuse Book
Author : William J. Haugen Light
Publisher : Charles C Thomas Pub Limited
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Neurobiology of Alcohol Abuse book written by William J. Haugen Light, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Alcohol and Alcoholism

Alcohol and Alcoholism Book
Author : John H. Hannigan,Linda P. Spear,Norman E. Spear,Charles R. Goodlett
Publisher : Psychology Press
Release : 1999-02-01
ISBN : 1135683980
Language : En, Es, Fr & De

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Book Description :

This is the first volume that focuses on the lifespan neurobehavioral factors likely to determine susceptibility to alcohol abuse and its consequences. The chapters offer careful analysis of the effects of ethanol on the fetus, the infant, the adolescent, and the adult. The authors include behavioral neuroscientists and clinical neuropsychologists. Their topics range from the neurochemical and neuroanatomical consequences of prenatal alcohol to the cognitive consequences of prenatal alcohol on preschool and school-age children. The impact of genetics on sensitivity to alcohol is considered in terms of analytic tests using techniques of behavioral genetics and molecular biology. The consequences of exposure to alcohol during breastfeeding are described in experiments with human infants. The alcoholism that develops in adulthood is analyzed through the experimental study of relapse from alcohol deprivation and assessment of neuropsychological impairments and treatment for alcoholics. Drawing on extensive research that has applied techniques from molecular neurobiology and tests of learning and memory to the clinical assessment and treatment of alcoholics. The volume answers recent questions raised by the National Institute of Alcohol Abuse and Alcoholism and the National Institute of Drug Abuse about the role of early experience in susceptibility to later abuse of alcohol and other drugs. Although epidemiological studies can describe the problem, solutions in terms of mechanisms that mediate these effects will be found only with the kinds of experimentally oriented approaches the chapter authors describe.

The Neurobiology of Addiction

The Neurobiology of Addiction Book
Author : Trevor W. Robbins,Barry J. Everitt,David J. Nutt
Publisher : Oxford University Press, USA
Release : 2010
ISBN : 0199562156
Language : En, Es, Fr & De

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Book Description :

In the past two decades, there have been astonishing advances in our understanding of the neurobiological basis and nature of drug addiction. We now know the initial molecular sites of action, at identified receptors, of virtually all of the major drugs of abuse including cocaine, heroin, and amphetamine, as well as legal drugs such as nicotine and alcohol. We also understand the main components of a 'reward system' and its connections to major brain regions involved in motivation and emotion, such as the amygdala, hippocampus, and prefrontal cortex. The Neurobiology of Addiction describes the latest advances in our understanding of addiction. It brings together world class researchers to debate the nature and extent of addiction, as well as its causes, consequences, and treatment. The focus of the book is on the brain processes underlying addiction, in terms of neural systems, neurochemical basis, and molecular changes. Several types of addiction are discussed ranging from illicit drugs - cocaine, amphetamine, and heroin to legal drugs - alcohol and nicotine. In addition, it explores increasingly common behavioural addictions such as gambling and obesity. Included are chapters on vulnerability to addiction, genetic factors, opponent motivational processes, animal models, relapse, cognitive deficits associated with drug abuse, new pharmacological treatments, and current controversies concerning different neuropsychological theories of addiction. Throughout, it reports on cutting edge research using brain imaging, and state of the art molecular methodology. The book will make fascinating reading for students and teachers in the field of neuroscience, pharmacology and psychology, as well as experts in the field.

Alcohol Addiction

Alcohol Addiction Book
Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
Publisher : Academic Press
Release : 2021-03-15
ISBN : 9780128167939
Language : En, Es, Fr & De

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Book Description :

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in Neurobiology of Addiction series, each volume addressing a specific area of addiction. Neurobiology of Alcohol Addiction, Volume 2 in the series, differentiates alcohol use, alcohol abuse and alcohol addiction, providing a clear path on how alcohol abuse can develop into an addiction. This volume includes thorough descriptions of the physiological and behavioral effects of alcohol abuse and addiction. In addition, the book clearly defines the neurobiological effects of alcohol into three distinct steps: Binge/Intoxication Stage, Withdrawal/Negative Affect Stage and last the Preoccupation/Anticipation Stage Highlights recent advances in understanding alcohol addiction Includes information regarding molecular, cellular, neurocircuitry, and behavioral levels of alcohol addictio Clearly outlines alcohol abuse vs alcohol addiction Defines neurobiological effects of alcohol addiction into 3 clear stages

Introduction to Addiction

Introduction to Addiction Book
Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
Publisher : Academic Press
Release : 2019-06-11
ISBN : 0128167955
Language : En, Es, Fr & De

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Book Description :

Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse. Provides neurobiological theories on how addiction works Explains addiction cycle stages of binge, withdrawal and anticipation Reviews the role of dopamine and the frontal cortex in addiction Discusses the neurocircuitry of reward and stress Includes animal models and neuroadaptational views on addiction

Alcohol Addiction

Alcohol Addiction Book
Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
Publisher : Academic Press
Release : 2021-03-01
ISBN : 0128167947
Language : En, Es, Fr & De

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Book Description :

Alcohol Addiction, Volume Three in the Neurobiology of Addiction series, provides a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction. Sections differentiate alcohol use, alcohol abuse and alcohol addiction, providing a clear path on how alcohol abuse can develop into an addiction. This volume includes thorough descriptions of the physiological and behavioral effects of alcohol abuse and addiction. In addition, the book clearly defines the neurobiological effects of alcohol into three distinct steps: Binge/Intoxication Stage, Withdrawal/Negative Affect Stage, and last the Preoccupation/Anticipation Stage. Highlights recent advances in our understanding of alcohol addiction Includes information regarding molecular, cellular, neurocircuitry and behavioral levels of alcohol addiction Clearly outlines alcohol abuse vs. alcohol addiction Defines the neurobiological effects of alcohol addiction in three clear stages

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption Book
Author : Todd E. Thiele
Publisher : Academic Press
Release : 2017-10-24
ISBN : 9780128124734
Language : En, Es, Fr & De

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Book Description :

"6. Newer Animal Studies on Oxytocin and Addiction" -- "7. Commentary on the Interpretation of Recent Animal Study Findings on Oxytocin and Addiction" -- "8. Oxytocin, Social Bonds, and Addiction" -- "9. Final Comments" -- "References" -- "Chapter Ten: Contribution of Urocortin to the Development of Excessive Drinking" -- "1. Introduction: The Promise of the CRF System" -- "2. The CRF/Urocortin System" -- "3. Complications of Studying Actions of CRF and Ucns" -- "4. Alcohol Sensitivity of the Ucn1 Neuropeptide System" -- "5. Genetic Associations of the EWcp Ucn1 System With Excessive Alcohol Consumption" -- "6. Effects of Excessive Alcohol Consumption on the Ucn1 System and EWcp" -- "7. Effects of Genetic Manipulations of EWcp Ucn1 System on Alcohol Consumption" -- "8. The Critical Role of the EWcp Ucn1 System in Excessive Alcohol Consumption" -- "9. Contrasting the Roles of Ucn1 vs CRF in Contribution to Excessive Alcohol Consumption" -- "Acknowledgments" -- "References

Neuroscience of Alcohol

Neuroscience of Alcohol Book
Author : Victor R. Preedy
Publisher : Academic Press
Release : 2019-03-19
ISBN : 0128131268
Language : En, Es, Fr & De

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Book Description :

Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of alcohol use, along with its effects on neurobiological function Discusses alcohol use as a component of dual-use and poly addictions Outlines numerous screening and treatment strategies for alcohol misuse Covers both the physical and psychological effects of alcohol use and withdrawals to provide a fully-formed view of alcohol dependency and its effects

Pour le Ballet de la desbauche

Pour le Ballet de la desbauche Book
Author : Anonim
Publisher : Unknown
Release : 2021-06-20
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Pour le Ballet de la desbauche book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Science of Addiction From Neurobiology to Treatment

The Science of Addiction  From Neurobiology to Treatment Book
Author : Carlton K. Erickson
Publisher : W. W. Norton & Company
Release : 2007-02-17
ISBN : 9780393076226
Language : En, Es, Fr & De

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Book Description :

Runner-up winner of the Hamilton Book Author Award, this book is a comprehensive overview of the neurobiology behind addictions. Neuroscience is clarifying the causes of compulsive alcohol and drug use––while also shedding light on what addiction is, what it is not, and how it can best be treated––in exciting and innovative ways. Current neurobiological research complements and enhances the approaches to addiction traditionally taken in social work and psychology. However, this important research is generally not presented in a forthright, jargon-free way that clearly illustrates its relevance to addiction professionals. The Science of Addiction presents a comprehensive overview of the roles that brain function and genetics play in addiction. It explains in an easy-to-understand way changes in the terminology and characterization of addiction that are emerging based upon new neurobiological research. The author goes on to describe the neuroanatomy and function of brain reward sites, and the genetics of alcohol and other drug dependence. Chapters on the basic pharmacology of stimulants and depressants, alcohol, and other drugs illustrate the specific and unique ways in which the brain and the central nervous system interact with, and are affected by, each of these substances Erickson discusses current and emerging treatments for chemical dependence, and how neuroscience helps us understand the way they work. The intent is to encourage an understanding of the body-mind connection. The busy clinical practitioner will find the chapter on how to read and interpret new research findings on the neurobiological basis of addiction useful and illuminating. This book will help the almost 21.6 million Americans, and millions more worldwide, who abuse or are dependent on drugs by teaching their caregivers (or them) about the latest addiction science research. It is also intended to help addiction professionals understand the foundations and applications of neuroscience, so that they will be able to better empathize with their patients and apply the science to principles of treatment.

Imaging the Addicted Brain

Imaging the Addicted Brain Book
Author : Anonim
Publisher : Academic Press
Release : 2016-08-05
ISBN : 0128039396
Language : En, Es, Fr & De

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Book Description :

Imaging the Addicted Brain, the latest volume in the International Review of Neurobiology series will appeal to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume focusses on the imaging of the brain addicted to food, gambling, tobacco, and opiates. Offers a unique perspective on how addiction affects the brain Covers a broad scope of addictions, including food, gambling, tobacco, and common psychogenic agents with a focus on their effects on the brain Focuses on the use of medical imaging methods, especially MRI, to explore and explain addiction in the brain