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Neural Repair And Regeneration After Spinal Cord Injury And Spine Trauma

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Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma Book
Author : Michael Fehlings,Brian Kwon,Alexander Vaccaro,F. Cumhur Oner
Publisher : Academic Press
Release : 2022-02-17
ISBN : 0128198362
Language : En, Es, Fr & De

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Book Description :

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout. These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma. Contains contributions by international authors Covers recent clinical trial advancements and findings and updates on ongoing trials Presents an overview of clinical practice guidelines for the management of traumatic spinal cord injury featured Provides the reader with insights regarding the translation of research from bench to bedside and the skills needed to understand the translational pathway using real-life examples

Neural Repair and Regeneration After Spinal Cord Injury and Spine Trauma

Neural Repair and Regeneration After Spinal Cord Injury and Spine Trauma Book
Author : Michael Fehlings,Brian Kwon,Alexander R. Vaccaro,F. Cumhur Oner
Publisher : Elsevier
Release : 2022-02-21
ISBN : 0128198354
Language : En, Es, Fr & De

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Book Description :

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout. These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma. Contains contributions by international authors Covers recent clinical trial advancements and findings and updates on ongoing trials Presents an overview of clinical practice guidelines for the management of traumatic spinal cord injury featured Provides the reader with insights regarding the translation of research from bench to bedside and the skills needed to understand the translational pathway using real-life examples

Spinal Cord Injury SCI Repair Strategies

Spinal Cord Injury  SCI  Repair Strategies Book
Author : Giuseppe Perale,Filippo Rossi
Publisher : Woodhead Publishing
Release : 2019-10-30
ISBN : 0081028083
Language : En, Es, Fr & De

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Book Description :

Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair. Covers current and future repair strategies for spinal cord injury repair Focuses on key research trends, clinics, biology and engineering Provides fundamentals on regenerative engineering and tissue engineering

Textbook of Neural Repair and Rehabilitation

Textbook of Neural Repair and Rehabilitation Book
Author : Michael Selzer,Stephanie Clarke,Leonardo Cohen,Gert Kwakkel,Robert Miller
Publisher : Cambridge University Press
Release : 2014-04-24
ISBN : 1107011671
Language : En, Es, Fr & De

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Book Description :

Volume 1 of the Textbook of Neural Repair and Rehabilitation covers the basic sciences relevant to recovery of function following injury to the nervous system.

Indwelling Neural Implants

Indwelling Neural Implants Book
Author : William M. Reichert
Publisher : CRC Press
Release : 2007-12-17
ISBN : 9781420009309
Language : En, Es, Fr & De

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Book Description :

Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment examines many of these challenges, paying particular attention to how the healing of tissues surrounding an implant can impact the intended use of a device. The contributions are divided into four sections · Part one examines wound healing from the initial insertion trauma through the inflammatory and repair process, explaining how the action of healing varies throughout different areas of the body. · Part two considers various performance issues specific to particular implant components, including those that arise from the chemical, mechanical, thermal, and electrical impact on surrounding tissues. It discusses challenges that result from chronic tissue stimulation and heat effects that occur with on-chip and telemetric processing. · Part three presents both in vitro and in vivo approaches to assessing wound healing response to materials. It includes the contribution of the developer of a chronic hollow fiber membrane implant who explains how an in vivo model is used to assess molecular transport in brain tissue surrounding the implant. · The final section evaluates molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between the electrode surface and the surrounding tissue. It also presents novel approaches to nerve regeneration and repair. This seminal work provides researchers with an up-to-date account of the progress in the field that they can build upon to bring us closer to realizing the full value of neural implants in combating otherwise intractable human health problems.

Spinal Cord Injury

Spinal Cord Injury Book
Author : National Institute of Neurological Diseases and Blindness (U.S.). Information Office
Publisher : Unknown
Release : 1968
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Spinal Cord Injury book written by National Institute of Neurological Diseases and Blindness (U.S.). Information Office, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

AOSpine Masters Series Volume 7 Spinal Cord Injury and Regeneration

AOSpine Masters Series  Volume 7  Spinal Cord Injury and Regeneration Book
Author : Luiz Roberto Gomes Vialle,Michael G. Fehlings,Norbert Weidner
Publisher : Thieme
Release : 2016-10-30
ISBN : 1626232288
Language : En, Es, Fr & De

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Book Description :

World-renowned experts share the latest updates in translational research as well as surgical and nonsurgical strategies for treating spinal cord injury Spinal cord injury (SCI) is a devastating, clinically challenging injury, leading to varying degrees of neurological function impairment and paralysis. Underlying biological mechanisms either inhibit or promote new growth in the spinal cord. Researchers have been making important discoveries about how neurons and their axons grow in the central nervous system and why they fail to regenerate after SCI. Although progress has been steady, there remains an urgent need to address issues in acute management such as early decompression and the use of biologics, as well as potential solutions for regeneration. Written by renowned experts in the ever-evolving field of SCI research and clinical practice, the 7th volume in the AOSpine Masters series is a state-of-the-art compendium on the latest in SCI diagnosis, spine surgery interventions, and long-term management. Each chapter contains pearls from leading spine specialists gleaned from the research laboratory and years of hands-on experience treating SCI patients in the emergency setting and long term. Key Features: Pathobiology, assessment, and diagnostic considerations The use of biomarkers as predictors of functional recovery Surgical and nonsurgical interventions for traumatic SCI The role of neural stem cells and biologics in spinal cord repair Functional and epidural stimulation and brain-computer interfaces The AOSpine Masters series, a copublication of Thieme and the AOSpine Foundation, addresses current clinical issues featuring international masters sharing their expertise in the core areas in the field. The goal of the series is to contribute to an evolving, dynamic model of evidence-based approach to spine care. This essential textbook delivers invaluable insights to spine surgeons, spinal cord injury clinicians and researchers and trainees, from translational researchers to experienced researchers and clinicians experienced in the operative and non-operative management of spinal cord injury.

Traumatic Brain and Spinal Cord Injury

Traumatic Brain and Spinal Cord Injury Book
Author : Cristina Morganti-Kossmann,Ramesh Raghupathi,Andrew Maas
Publisher : Cambridge University Press
Release : 2012-07-19
ISBN : 1139536354
Language : En, Es, Fr & De

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Book Description :

Traumatic Brain and Spinal Cord Injury comprehensively covers the medical and pathological issues related to neurotrauma and its often devastating consequences. Written by globally renowned experts in the field, both clinicians and researchers will find this book invaluable to update their knowledge. This volume is divided into two sections, one covering the brain, the other the spinal cord. Each section discusses the following topics: • The demographic in the developed and developing world where neurotrauma is witnessing a massive expansion • Major clinical issues including advanced semi-experimental monitoring techniques utilized by neurosurgeons and intensivists and the potential use of identifying markers of tissue injury • Overview of major pathophysiological changes • The development of animal models; successes and limitations • Past, current and future therapeutic strategies including rehabilitative opportunities. Presenting the most up-to-date clinical and experimental research in neurotrauma, this volume is essential reading for neurologists, neurosurgeons, intensive care physicians and rehabilitative physicians.

Essentials of Spinal Cord Injury

Essentials of Spinal Cord Injury Book
Author : Michael G. Fehlings,Alexander R. Vaccaro,Maxwell Boakye
Publisher : Thieme
Release : 2012-10-29
ISBN : 1604067276
Language : En, Es, Fr & De

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Book Description :

Essentials of Spinal Cord Injury is written for the spinal cord injury (SCI) team and reflects the multidisciplinary nature of treating patients with SCI. It integrates emerging medical and surgical approaches to SCI with neuroanatomy, neurophysiology, neuroimaging, neuroplasticity, and cellular transplantation. This comprehensive yet concise reference will enable neurosurgeons, orthopedic surgeons, neurologists, and allied health professionals caring for SCI patients to translate research results into patient care. It is also an excellent resource for those preparing for the board exam in SCI medicine. Key Features: Material is cross-referenced to highlight relationships between the different areas of SCI Chapters are concise, focused, and include key points, pearls, and pitfalls An Overview of the Literature table is provided in most chapters, giving readers a meaningful distillation of each publication referenced Each editor is a world-renowned expert in one of these core disciplines involved in the management of SCI patients: neurosurgery, orthopedic surgery, spinal cord science, and rehabilitative medicine This is a must-have guide that all neurosurgeons, orthopedic surgeons, neurologists, and allied health professionals involved in the care of spinal cord injury patients should have on their bookshelf.

Neuroprotection

Neuroprotection Book
Author : Matilde Otero-Losada,Francisco Capani,Santiago Perez Lloret
Publisher : BoD – Books on Demand
Release : 2020-11-26
ISBN : 1838804390
Language : En, Es, Fr & De

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Book Description :

Neurological disease affects nearly 25%–30% of the world’s population, exerting enormous financial strain on the healthcare system. Estimated current costs are around $800 annual billion, and this number is expected to increase exponentially as the global population ages. As such, new and alternative neuroprotective strategies are urgently needed. This book examines some of the most promising approaches in neuroprotection as well as discusses current goals and prospects. Organized into three sections, chapters cover such topics as the use of cannabinoids, medicinal plants, and essential oils in Alzheimer’s and Parkinson’s; protein misfolding and the neuroprotective potential of vitamin E in cerebral ischemia; and potential new neurological treatments and their mechanisms of action.

Management of Spinal Cord Injuries E Book

Management of Spinal Cord Injuries E Book Book
Author : Lisa Harvey
Publisher : Elsevier Health Sciences
Release : 2008-01-10
ISBN : 0702036153
Language : En, Es, Fr & De

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Book Description :

Combining 25 years of clinical, research and teaching experience, Dr Lisa Harvey provides an innovative 5-step approach to the physiotherapy management of people with spinal cord injury. Based on the International Classification of Functioning, this approach emphasises the importance of setting goals which are purposeful and meaningful to the patient. These goals are related to performance of motor tasks analysed in terms of 6 key impairments. The assessment and treatment performance of each of these impairments for people with spinal cord injury is described in the following chapters: training motor tasks strength training contracture management pain management respiratory management cardiovascular fitness training Dr Harvey develops readers' problem-solving skills equipping them to manage all types of spinal cord injuries. Central to these skills is an understanding of how people with different patterns of paralysis perform motor tasks and the importance of differentmuscles for motor tasks such as: transfers and bed mobility of people wheelchair mobility hand function for people with tetraplegia standing and walking with lower limb paralysis This book is for students and junior physiotherapists with little or no experience in the area of spinal cord injury but with a general understanding of the principles of physiotherapy. It is also a useful tool for experienced clinicians, including those keen to explore the evidence base that supports different physiotherapy interventions.

Essentials of Spinal Cord Injury Medicine

Essentials of Spinal Cord Injury Medicine Book
Author : Yannis Dionyssiotis
Publisher : BoD – Books on Demand
Release : 2018-06-13
ISBN : 1789232481
Language : En, Es, Fr & De

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Book Description :

Spinal cord injury is a severe condition leading to serious neurological dysfunctions and changes a person's life in a sudden way. Understanding the pathophysiology of spinal cord injury will improve the prognosis and reintegration to the society of spinal cord-injured subjects. The book Essentials in Spinal Cord Injury Medicine includes seven chapters with valuable information addressing hot topics related to spinal cord injury, ranging from pathophysiology, nontraumatic spinal cord injury, complications to exoskeletons, and research therapies with mesenchymal stem cells. The book could be a valued reference for physiatrists, neurosurgeons, orthopedic surgeons, neurologists and physical therapists.

Spinal Cord Injury Therapy

Spinal Cord Injury Therapy Book
Author : José Juan Antonio Ibarra Arias,Gabriel Guízar-Sahagún,Elisa García-Vences
Publisher : BoD – Books on Demand
Release : 2019-11-27
ISBN : 1789841615
Language : En, Es, Fr & De

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Book Description :

Spinal cord injury (SCI) is one of the main pathologies causing significant loss of neurological function. Therefore, a variety of pharmacological and non-pharmacological therapies are the aims of several studies. To provide the best care, it is important to know and understand the therapeutic approaches that have shown important progress in this topic. This book contains eight chapters that are divided into three sections: Introduction, Pharmacological Therapies, and Non-Pharmacological Therapies. The authors of the chapters deal with the pathophysiology of SCI, the effect of antioxidant and immunosuppressive agents, stem cell-based therapies, the use of cultured cells for transference or transplantation, and the application of non-invasive modalities (transcutaneous electrical spinal cord stimulation, etc.) for SCI rehabilitation.

Paraplegia

Paraplegia Book
Author : José Juan Antonio Ibarra Arias,Carlos Alberto Cuellar Ramos
Publisher : BoD – Books on Demand
Release : 2021-05-12
ISBN : 1789855411
Language : En, Es, Fr & De

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Book Description :

In the last decade, diverse research areas have developed novel approaches to overcome dysfunctions after a spinal cord injury (SCI). Even though motor restoration attracts the most clinical attention, sensory, autonomic, and mental health are also aspects fundamental to improving the quality of life of SCI patients. Over four sections of therapeutic, rehabilitation, and technological approaches, this book examines preclinical and clinical studies using mesenchymal stem cells and pharmacological or electrical stimulation strategies. Chapters also address the impact of paraplegia and associated loss of autonomic functions, including bowel and sexual dysfunction, as well as the convergence of new technologies aimed at providing postural support and enhancing mobility.

Spinal Cord Medicine

Spinal Cord Medicine Book
Author : Denise I. Campagnolo,Steven Kirshblum,Mark S. Nash,Robert F. Heary,Peter H. Gorman
Publisher : Lippincott Williams & Wilkins
Release : 2011-12-07
ISBN : 1451154275
Language : En, Es, Fr & De

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Book Description :

This comprehensive and practical reference is the perfect resource for the medical specialist treating persons with spinal cord injuries. The book provides detail about all aspects of spinal cord injury and disease. The initial seven chapters present the history, anatomy, imaging, epidemiology, and general acute management of spinal cord injury. The next eleven chapters deal with medical aspects of spinal cord damage, such as pulmonary management and the neurogenic bladder. Chapters on rehabilitation are followed by nine chapters dealing with diseases that cause non-traumatic spinal cord injury. A comprehensive imaging chapter is included with 30 figures which provide the reader with an excellent resource to understand the complex issues of imaging the spine and spinal cord.

Recovery of Motor Function Following Spinal Cord Injury

Recovery of Motor Function Following Spinal Cord Injury Book
Author : Heidi Fuller,Monte Gates
Publisher : BoD – Books on Demand
Release : 2016-08-17
ISBN : 9535124978
Language : En, Es, Fr & De

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Book Description :

Restoration of motor function following spinal cord injury is a complex and challenging task. By reviewing emerging cellular, pharmacological, rehabilitative, as well as surgical approaches, this book seeks to highlight promising therapeutic strategies for the repair and regeneration of motor circuitry. The multidisciplinary nature of these approaches illustrates various routes to bridging the gap between the bench and the bedside and to identify the challenges that must be overcome in order to bring about a viable therapeutic strategy for spinal cord injury patients.

Physical Management in Neurological Rehabilitation

Physical Management in Neurological Rehabilitation Book
Author : Maria Stokes
Publisher : Elsevier Health Sciences
Release : 2004
ISBN : 0723432856
Language : En, Es, Fr & De

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Book Description :

Providing an introduction to the basic concepts of neurology, neurological conditions the differing methods of physiotherapy, this text brings together contributions from an experienced team of experts in the field.

Diagnosis and Treatment of Spinal Cord Injury

Diagnosis and Treatment of Spinal Cord Injury Book
Author : Rajkumar Rajendram,Victor R. Preedy,Colin R. Martin
Publisher : Academic Press
Release : 2022-05-10
ISBN : 0128224991
Language : En, Es, Fr & De

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Book Description :

Diagnosis and Treatment of Spinal Cord Injury will enhance readers’ understanding of the complexities of the diagnosis and management of spinal cord injuries. Featuring chapters on drug delivery, exercise, and rehabilitation, this volume discusses in detail the impact of the clinical features, diagnosis, management, and long-term prognosis of spinal cord injuries on the lives of those affected. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand spinal cord injuries. Covers both the diagnosis and treatment of spinal cord injury Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding Features chapters on epidemiology and pain Includes MRI usage, biomarkers, and stem cell and gene therapy for management of spinal cord injury Discusses pain reduction, drug delivery, and rehabilitation

Neurological Aspects of Spinal Cord Injury

Neurological Aspects of Spinal Cord Injury Book
Author : Norbert Weidner,Rüdiger Rupp,Keith Tansey
Publisher : Springer
Release : 2017-01-06
ISBN : 9783319462912
Language : En, Es, Fr & De

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Book Description :

This clinically focused book aims to cover for the first time all of the neurological aspects relevant to the diagnosis and treatment of spinal cord disease. Furthermore, innovative neurorestorative therapeutic strategies - aiming for repair of the damaged spinal cord and/or reorganization of the remaining nervous system - with significant potential for translation into clinical routine are presented. The book covers a comprehensive list of topics, including epidemiology, neuroanatomy, etiology of compressive and non-compressive spinal cord injury, imaging, neurophysiology, neurological sequelae, and complications with emphasis on dysfunction of the autonomic nervous system. Both clinically established and preclinical therapies are discussed in detail. The book is suited for trainees and practicing clinicians including neurologists, spine surgeons, rehabilitation specialists, neuroradiologists, and occupational/physical therapists; it will also be of value to neuroscientists involved in research into spinal cord disease.

Trends in Cell Signaling Pathways in Neuronal Fate Decision

Trends in Cell Signaling Pathways in Neuronal Fate Decision Book
Author : Anonim
Publisher : Unknown
Release : 2013
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Trends in Cell Signaling Pathways in Neuronal Fate Decision book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.